Elusidation of a regulatory mechanism by Peroxiredoxin 6 (Prx-6) in inflammatory bowel desease(IBD

Research Project

Project/Area Number	21790680
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Gastroenterology
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	OKADA Hitomi Kyoto Prefectural University of Medicine, 医学研究科, 助教(寄附講座) (60533023)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	腸管炎症性疾患 / 酸化ストレス
Research Abstract	It is suggested that Peroxiredoxin 6 (Prx-6) may provide cytoprotection and wound healing in YAMC cells. Ulcerative colitis (UC) patients were treated using granulocytapheresis (GCAP). After the treatment, Prx6 in the patients, which observed the therapeutic effect, increased. These results show that Prx-6 may be involved in mechanisms of inflammatory bowel disease (IBD) and be used as a marker of examination the therapeutic effect of IBD.

Report

(3 results)