| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
Our new purification method did not change the immune responses to rP34. PBMC_s from allergic subjects, but not from control subjects, showed an enhanced allergen-stimulated proliferation response to endotoxin-free recombinant P34. Furthermore, the ImmunoCAP system using our purified recombinant P34 that retains its tertiary structure may be useful for the identification of patients with soybean allergy or for the indication of outgrown allergy. Purified recombinant P34 may be useful tool for the evaluation of soybean allergies, and a specific immunotherapy for soybean allergy based on recombinant should be considered.
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