Investigation on screening method of the head and neck carcinogenic risk by expiration air with ethanol drinking.

• Project/Area Number: 21791601
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Otorhinolaryngology
• Research Institution: Chiba Cancer Center (Research Institute) (2011-2012); Sasaki Institute (2009-2010)
• Principal Investigator: HAYASHI Tomomasa 千葉県がんセンター(研究所), 頭頸科, 医長 (20510366)
• Project Period (FY): 2009 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 咽頭科学 / 発がん

Research Abstract

Early detection of the head and neck cancer is very important to preserve function of pharynx and larynx. Detection of high risk character of head and neck cancer is also easy to treat with functional preservation. One of the carcinogens of head and neck is acetaldehyde and the person who is ALDH2 heterogamete type is high risk of head and neck cancer. This research is using to expiration of ethanol drinking person to detect the high risk person. But, instability of acetaldehyde is very difficult to this research and I cannot obtain any result in this research.