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Periosteal expansion osteogenesis combined with bone morphogenetic protein

Research Project

Project/Area Number 21792024
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionKyushu Dental College

Principal Investigator

YAMAUCHI Kensuke  Kyushu Dental College, 歯学部, 助教 (10364150)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords口腔外科学一般 / 人工骨 / 骨膜 / 骨膜伸展 / 骨延長 / 骨造成 / インプラント / 骨形成因子 / 膜性骨化
Research Abstract

The alveolar form at the experimental region was changed dramatically following lateral expansion with the β-TCP block. Newly formed bone was observed in the gap between the bone and the β-TCP block, as well as on the lateral surface of the block. Moreover, the replacement of large parts of the β-TCP with newly formed bone was observed in the β-TCP block area. The β-TCP block worked as space-maker under the soft tissue, including the periosteum, and also acted as a substitute for original bone and this bone substitute was effective material for bone augmentation in both methods. However, BMP induction for the gap between B-TCP block and original bone didn't work as stable accelerator for the bone formation. It seems that some mediums are needed to obtain stable results for new bone formation.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (13 results)

All 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 3 results) Presentation (6 results) Remarks (1 results)

  • [Journal Article] Histological and histomorphometrical comparative study of beta-tricalcium phosphate block grafts and periosteal expansion osteogenesis for alveolar bone augmentation.2010

    • Author(s)
      Yamauchi K, Takahashi T, Funaki K, Hamada Y, Yamashita Y
    • Journal Title

      Int J Oral Maxillofac Surg. 39

      Pages: 1000-1006

    • Related Report
      2010 Final Research Report
  • [Journal Article] Histological and Histomorphometrical Comparative Study of b-Tricalcium Phosphate Block Grafts and Periosteal Expansion Osteogenesis for Alveolar Bone Augmentation2010

    • Author(s)
      Kensuke Yamauchi, Tetsu Takahashi Katsuyuki Funaki, Yusuke Hamada, Yoshihiro Yamashita
    • Journal Title

      International Journal of Oral Maxillofacial Surgery

      Volume: 39 Pages: 1000-1006

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Horizontal Alveolar Ridge Augmentation Using Distraction Osteogenesis : Comparison with a Bone-splitting Method in a Dog Model.2009

    • Author(s)
      Funaki K, Takahashi T, Yamauchi K
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107

      Pages: 350-358

    • Related Report
      2010 Final Research Report
  • [Journal Article] Implant placement for periosteal expansion osteogenesis using beta-tricalcium phosphate block : and experimental study in dogs.2009

    • Author(s)
      Yamauchi K, Takahashi T, Funaki K, Miyamoto I, Yamashita Y
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86

      Pages: 861-869

    • Related Report
      2010 Final Research Report
  • [Journal Article] Implant placement for Periosteal Expansion Osteogenesis using β-tricalcium phophate block : An experimental study in dogs2009

    • Author(s)
      Kensuke Yamauchi, Tetsu Takahashi, Katsuyuki Funaki, lkuya Miyamoto, Yoshihiro Yamashita
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 108

      Pages: 861-866

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Horizontal Alveolar Ridge Augmentation Using Distraction Osteogenes is : Comparison with a Bone-splitting Method in a Dog Model2009

    • Author(s)
      K.Funaki, T.Takahashi, K.Yamauchi
    • Journal Title

      Oral Surgery, Oral Mediclne, Oral Pathology, Oral Radiology, and Endodontology 107

      Pages: 350-358

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 仮骨延長術2010

    • Author(s)
      山内健介、高橋哲
    • Organizer
      臨床再生歯科研究会
    • Year and Date
      2010-11-10
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 下顎骨辺縁切除後に骨移植と歯槽骨延長を同時併用した1例2009

    • Author(s)
      山内健介、菅崎紳、児玉崇、宮本郁也、山下善弘、高橋哲
    • Organizer
      日本顎顔面インプラント学会
    • Year and Date
      2009-12-12
    • Related Report
      2010 Final Research Report
  • [Presentation] β-TCPブロックを用いた歯槽骨造成法-移植と骨膜進展の組織学的比較検討2009

    • Author(s)
      山内健介、児玉崇、宮本郁也、山下善弘、高橋哲
    • Organizer
      日本口腔インプラント学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-09-26
    • Related Report
      2010 Final Research Report
  • [Presentation] β-TCPブロックを用いた歯槽骨造成法-移植と骨膜進展の組織学的比較検討-2009

    • Author(s)
      山内健介、児玉崇、宮本郁也、山下善弘、高橋哲
    • Organizer
      第39回(社)日本口腔インプラント学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] β-TCPブロックを用いた骨膜進展骨形成法の実験的研究2009

    • Author(s)
      山内健介、金氏毅、宮本郁也、山下善弘、高橋哲
    • Organizer
      九州歯科学会総会
    • Place of Presentation
      北九州
    • Year and Date
      2009-05-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Histological and HistomorphometricalComparative Study of β-Tricalcium Phosphate Block Grafts and Periosteal Expansion Osteogenesis for Alveolar Bone Augmentation.2009

    • Author(s)
      K.Yamauchi, K.Funaki, I.Miyamoto, Y.Yamashita, T.Takahashi.
    • Organizer
      49th Korean Congress of Oral and Maxillofacial
    • Place of Presentation
      Surgeons
    • Year and Date
      2009-04-10
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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