Fundamental study on mechanism of pressure ulcer developing.-Response to pressure of skin and muscle cells.-
| Project/Area Number |
21792175
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fundamental nursing
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| Research Institution | Teikyo University (2010)
Shiga University of Medical Science (2009) |
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Principal Investigator |
TAKADA Naoko Teikyo University, 医療技術学部, 講師 (10432303)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 褥瘡 / 皮膚線維芽細胞 / 筋管細胞 / 機械的刺激 / アポトーシス / 低酸素刺激 / 皮膚繊維芽細胞 / 細胞外マトリックス / BMPファミリー / 発生要因 |
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| Research Abstract |
The purpose of this study was reveal mechanism of pressure ulcer developing by using the cell that composed the skin and the muscle. As a result, the application of external pressure induced the expression of gene not thought to be related to the generation of the pressure ulcer before. And, the gene that increases by a current research was confirmed by the immunostaining. In addition, I made three-dimensionnal culture model that similar living body.
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Report
(3 results)
Research Products
(2 results)
