Fundamental study on mechanism of pressure ulcer developing.-Response to pressure of skin and muscle cells.-
Project/Area Number |
21792175
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Fundamental nursing
|
Research Institution | Teikyo University (2010) Shiga University of Medical Science (2009) |
Principal Investigator |
TAKADA Naoko Teikyo University, 医療技術学部, 講師 (10432303)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 褥瘡 / 皮膚線維芽細胞 / 筋管細胞 / 機械的刺激 / アポトーシス / 低酸素刺激 / 皮膚繊維芽細胞 / 細胞外マトリックス / BMPファミリー / 発生要因 |
Research Abstract |
The purpose of this study was reveal mechanism of pressure ulcer developing by using the cell that composed the skin and the muscle. As a result, the application of external pressure induced the expression of gene not thought to be related to the generation of the pressure ulcer before. And, the gene that increases by a current research was confirmed by the immunostaining. In addition, I made three-dimensionnal culture model that similar living body.
|
Report
(3 results)
Research Products
(2 results)