Analysis of periostin isoform expressed uniquely in periodontal ligament tissue
| Project/Area Number |
21890137
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Periodontal dentistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
MAEDA Kenichiro Osaka University, 歯学部附属病院, 医員 (90552068)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥2,561,000 (Direct Cost: ¥1,970,000、Indirect Cost: ¥591,000)
Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000)
Fiscal Year 2009: ¥1,326,000 (Direct Cost: ¥1,020,000、Indirect Cost: ¥306,000)
|
|---|
| Keywords | 歯根膜組織 / ペリオスチン |
|---|
| Research Abstract |
We were enable to collect very high purity both periostin isofrom uniquely expressed in periodontal ligament (PDL-POSTIN) and full length periostin proteins (FULL-POSTIN) with adenovirus infection. Using these both purified proteins, we have found that affinity to Integrin αvβ3 of PDL-POSTIN is higher than that of FULL-POSTIN. These results suggest that PDL-POSTIN may have an important role in homeostatic mechanism and regeneration of periodontal tissue.
|
Report
(3 results)
Research Products
(2 results)
