| Project/Area Number |
22500788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
|
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| Research Institution | Mukogawa Women's University |
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Principal Investigator |
FUKUDA Mitsuru 武庫川女子大学, 生活環境学部, 教授 (90098517)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Maki 武庫川女子大学, 生活環境学部, 助手 (70550789)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | TNF一α / アグリコン / イソフラボン / ラット / 乳酸発酵 / 大豆 / 炎症性サイトカ / 大豆ヨーグルト / 内臓脂肪 / ＴＮＦ－α / 炎症性サイトカイン / ヨーグルト / ポリアミン / 脂肪組織 / TNF-α |
|---|
| Research Abstract |
In plasma of rats fed a high fat and high cholesterol diet, isofavone level was increased and TNF-a level was decreased by ingestion of soy yogurt. The increase of visceral fat mass was suppressed and the gene expression of TNF-a in visceral fat tissue was down-regulated by ingestion of soy yogurt. It was assumed that the visceral fat mass in rats was decreased by ingestion of soy yogurt and thereby the level of plasma inflammatory cytokine was mainly reduced through modulation of gene expression in visceral fat tissue.
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