| Project/Area Number |
22700595
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical education
|
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| Research Institution | Matsusho Gakuen Junior College |
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Principal Investigator |
|
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
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| Keywords | 運動 / 海馬 / 神経新生 / microRNA |
|---|
| Research Abstract |
Voluntary exercise has been reported to promote neurogenesis in the hippocampus and to improve learning and memory, the function of hippocampus. However, the mechanisms is yet unknown. Recently, it is suggested that short forms of RNA, microRNA(miRNA), may be involved in the neuronal differentiation and neurogenesis. In the present study, the expression level of miRNAs in the hippocampus was investigated after 12 days of voluntary running exercise in the mouse. As the result, no significant change was detected in the hippocampal miRNAs investigated. There may be a possibility that the expression of miRNAs would be changed in the early phase of voluntary exercise or acute exercise.
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