Brain metabdic changes for cancer chemotherapy
| Project/Area Number |
22790580
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East |
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Principal Investigator |
OGAWA Asao 独立行政法人国立がん研究センター, 臨床開発センター, 室長 (10466196)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 疫学 / 脳科学 / 神経イメージング / 悪性腫瘍 |
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| Research Abstract |
Although chemotherapy is beneficial in the treatment of a variety of malignancies, it is also associated with a number of adverse effects. In addition, cognitive changes following chemotherapy sometimes referred to as "chemobrain" or chemotherapy-related cognitive impairment. However, the causality of the associations or biologic mechanisms for the cognitive impairments are uncertain. We have measured the metabolic changes of the brain in the cancer treatment with MR spectroscopy. The study proceeded as scheduled, and upon comlpletion of follow up study, carried out the analysis.
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Report
(3 results)
Research Products
(72 results)
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[Journal Article] Usefulness of pharmacist-assisted screening and psychiatric referral program for outpatients with cancer undergoing chemotherapy2011
Author(s)
Ito, T., Shimizu, K., Ichida, Y., Ishibashi, Y., Akizuki, N., Ogawa, A., Fujimori, M., Kaneko, N., Ueda, I., Nakayama, K., and Uchitomi, Y.
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Journal Title
Psychooncology
Volume: 20(6)
Issue: 6
Pages: 647-654
DOI
Related Report
Peer Reviewed
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[Journal Article] Availability of Psychiatric Consultation-Liaison Services as an Integral Component of Palliative Care Programs at Japanese Cancer Hospitals2011
Author(s)
Ogawa, A., Nouno, J., Shirai, Y., Shibayama, O., Kondo, K., Yokoo, M., Takei, H., Koga, H., Fujisawa, D., Shimizu, K., and Uchitomi, Y.
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Journal Title
Jpn J Clin Oncol
Volume: 42
Issue: 1
Pages: 42-52
DOI
Related Report
Peer Reviewed
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[Journal Article] Chronic repetitive transcranial magnetic stimulation increases hippocampal neurogenesis in rats2011
Author(s)
Ueyama, E., Ukai, S., Ogawa, A., Yamamoto, M., Kawaguchi, S., Ishii, R., Shinosaki, K.
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Journal Title
Psychiatry Clin Neurosci
Volume: 65
Issue: 1
Pages: 77-81
DOI
Related Report
Peer Reviewed
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[Journal Article] Patients perception of the usefulness of a question prompt sheet for advanced cancer patients when deciding the initial treatment : a randomized, controlled trial2011
Author(s)
Shirai, Y., Fujimori, M., Ogawa, A., Yamada, Y., Nishiwaki, Y., Ohtsu, A., Uchitomi, Y.
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Journal Title
Psychooncology
Volume: (Epub ahead of print)
Issue: 7
Pages: 706-713
DOI
Related Report
Peer Reviewed
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[Journal Article] Treatment Response to Psychiatric Intervention and Predictors of Response Among Cancer Patients with Adjustment Disorders2011
Author(s)
Shimizu, K., Nobuya, A., Nakaya, N., Fujimori, M., Fujisawa, D., Ogawa, A., Uchitomi, Y.
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Journal Title
Journal of Pain and Symptom Management
Volume: 41(4)
Issue: 4
Pages: 684-691
DOI
Related Report
Peer Reviewed
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[Journal Article] Feasibility and usefulness of the Distress Screening Program in Ambulatory Care in clinical oncology practice2010
Author(s)
Shimizu, K., Ishibashi, Y., Umezawa, S., Izumi, H., Akizuki, N., Ogawa, A., Fujiwara, Y., Ando, M., Katsumata, N., Tamura, K., Kouno, T., Shimizu, C., Yonemori, K., Yunokawa, M., Uchitomi, Y.
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Journal Title
Psychooncology
Volume: 19
Issue: 7
Pages: 718-25
DOI
Related Report
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[Journal Article] Psychiatric disorders and stress factors experienced by staff members in cancer hospitals : a preliminary finding from psychiatric consultation service at National Cancer Center Hospitals in Japan2010
Author(s)
Asai, M., Akizuki, N., Akechi, T., Nakano, T., Shimizu, K., Umezawa, S., Ogawa, A., Matsui, Y., Uchitomi, Y.
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Journal Title
Palliat Support Care
Volume: 8
Issue: 3
Pages: 291-5
DOI
Related Report
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[Journal Article] Feasibility and usefulness of the 'Distress Screening Program in Ambulatory Care' in clinical oncology practice2010
Author(s)
Shimizu, K., Ishibashi, Y., Umezawa, S., Izumi, H., Akizuki, N., Oeawa, A., Fujiwara, Y., Ando, M., Katsumata, N., Tamura, K., Kouno, T., Shimizu, C, Yonemori, K., Yunokawa, M., Uchitomi, Y.
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Journal Title
Psychooncology
Volume: 19
Pages: 718-25
Related Report
Peer Reviewed
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[Book] 精神腫瘍学2011
Author(s)
内富庸介、小川朝生(編)
Total Pages
413
Publisher
医学書院
Related Report
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