Study of electrical stimulation therapy for optic neuropathies
Project/Area Number |
22791658
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Ophthalmology
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Research Institution | Osaka University |
Principal Investigator |
MORIMOTO Takeshi 大阪大学, 医学(系)研究科(研究院), 准教授 (00530198)
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Project Period (FY) |
2010-04-01 – 2014-03-31
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | 神経保護 / 電気刺激治療 / 網膜神経節細胞 / 視神経疾患 / 網膜神経保護 / 難治性視神経症 / 電気刺激 / IGF-1 / 視神経 |
Research Abstract |
In the present study, I investigated the mechanism underlying electrical stimulation -induced neuroprotection of retinal ganglion cells and examined the effect of electrical stimulation on various optic neuropathies. I elucidated that retinal neurovascular coupling was activated by electrical stimulation to exert neuroprotection. And moreover I found that about 30% of patients improved their vision after electrical stimulation treatment. Finally I established the protocol of electrical stimulation therapy for various optic neuropathies.
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Report
(5 results)
Research Products
(66 results)
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[Journal Article] Feasibility of 2nd generation STS retinal prosthesis in dogs.2013
Author(s)
Fujikado T, Kamei M, Sakaguchi H, Kanda H, Morimoto T, Nishida K, Kishima H, Maruo T, Oosawa K, Ozawa M, Nishida K
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Journal Title
Conf Proc IEEE Eng Med Biol Soc
Volume: Jul
Pages: 3119-3121
DOI
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Peer Reviewed
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[Presentation] 高次収差と弱視2011
Author(s)
森本壮
Organizer
第115回日本眼科学会総会
Place of Presentation
東京国際フォーラム(招待講演)
Year and Date
2011-05-12
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