| Project/Area Number |
22791932
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
BAN Seiji 愛知学院大学, 歯学部, 非常勤講師 (10159105)
MACHIGASHIRA Miho 鹿児島大学, 医歯学総合研究科, 講師 (80253897)
MIYAMOTO Motoharu 鹿児島大学, 医歯学総合研究科, 助教 (50452941)
KONO Hiroshi 鹿児島大学, 医歯学総合研究科, 助教 (20507165)
TAKEUCHI Hironobu 鹿児島大学, 医歯学総合研究科, 助教 (70452951)
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| Research Collaborator |
NODA Makoto 鹿児島大学, 医歯学総合研究科, 大学院生
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | ジルコニア / 表面改質 / インプラント / アパタイト / 骨芽細胞 |
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| Research Abstract |
The aim of this study were to develop a novel HA coating method on zirconia using glass coating technique and to investigate the response of osteoblast-like cells to the surface of hydroxyapatite-containing glass coating on zirconia(HA-G-Zr) in comparison to yttria stabilized zirconia(Y-TZP). The hydroxyapatite containing glass-coated zirconia could be systematically produced using the glass coating technique. Osteblast-like cells on HA-G-Zr plates showed higher differentiation and mineralization than Y-TZP. These results demonstrated that HA-G-Zr showed better cellular biocompatibility than Y-TZP.
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