Study of regulation of anti-diuretic hormone gene expression
Project/Area Number |
23580388
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Applied animal science
|
Research Institution | Okayama University (2013) Nagoya University (2011-2012) |
Principal Investigator |
SAITO Noboru 岡山大学, その他の研究科, 教授 (40211924)
|
Co-Investigator(Renkei-kenkyūsha) |
HARADA Nobuhiro 藤田保険衛生大学, 医学部, 教授 (00189705)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | ニワトリ / 浸透圧調節 / 抗利尿ホルモン / 遺伝子発現 / 浸透圧刺激 / 転写調節因子 / TPR / TonEBP / アルギニンバソトシン / TRPファミリー / 転写因子 / 高浸透圧刺激 / 脳 |
Research Abstract |
We suggested that Tonicity-responsive Enhancer Binding Protein (TonEBP) participated in expression of birds adjustment by the osmoregulation of arginine vasotocin (AVT) which was antidiuretic hormone. We revealed that TonEBP bound to the upper region of the AVT gene by the gel mobility shift assay method. In addition, an immunoreactive localization of TonEBP was observed in PVN (para-ventricular nucleus) and SON (supra optic nucleus) with many VT-positive cells. It was suggested that TRPV (Transient Receptor Potential Vanilloid) participated in the osmoregulation of birds.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Sex differences in brain aromatase activity : genomic and non-genomic controls2011
Author(s)
Balthazart, J., Charlier, T.D., Cornil, C.A., Dickens, M.J., Harada, N., Konkle, A.T.M., Voigt, C., Ball, G.F.
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Journal Title
Front. Neuroendocrin
Volume: 2
Pages: 34-34
DOI
Related Report
Peer Reviewed
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[Journal Article] 1-(2,4-Dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl) propane inhibits melanin synthesis by dual mechanism2011
Author(s)
Niki, Y., Yoshida, M., Ando, H., Wakamatsu, K., et al
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Journal Title
J.Dermatol.Sci.
Volume: 63
Pages: 115-121
DOI
Related Report
Peer Reviewed
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[Journal Article] Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathological role of androstene-3b, 17b-diol2011
Author(s)
Honma, N., Saji, S., Hirose, M., Horiguchi, S., Kuroi, K., Hayashi, S., Utsumi, T., & Harada, N.
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Journal Title
Cancer Sci
Volume: 102
Issue: 10
Pages: 1848-1854
DOI
Related Report
Peer Reviewed
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