Association of oral health with lifestyle-related diseases: cohort studies of dentists and the elderly

• Project/Area Number: 23590788
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Nagoya University
• Principal Investigator: Kenji Wakai 名古屋大学, 医学(系)研究科(研究院), 教授 (50270989)
• Co-Investigator(Kenkyū-buntansha): NAITO MARIKO 名古屋大学, 大学院医学系研究科, 准教授 (10378010) ; KAWAMURA TAKASHI 京都大学, 環境安全保健機構健康科学センター, 教授 (10252230)
• Project Period (FY): 2011-04-28 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 口腔状態 / 口腔衛生習慣 / コホート研究 / 虚血性心疾患 / 脳卒中 / 肺炎 / 大腿骨頚部骨折 / 糖尿病 / 死亡リスク / 歯磨き習慣 / 歯間部清掃器具 / 歯牙喪失 / 高血圧症

Outline of Final Research Achievements

We conducted a cohort or follow-up study of 21,260 dentists with a mean follow-up of 9.5 years. The risk was significantly increased among respondents with many teeth lost for total and pneumonia mortality and stroke incidence whereas no such a significant association was found for incidence of ischemic heart disease. In addition, the frequency of blushing teeth was inversely correlated with the risk of stroke incidence.

Research Products

• [Journal Article] Tooth loss and risk of hip fracture: a prospective study of male Japanese dentists. (2013)
  • Author(s): Wakai K, Naito M, Naito T, Kojima M, Nakagaki H, Umemura O, Yokota M, Hanada N, Kawamura T
  • Journal Title: Community Dent Oral Epidemiol Volume: 印刷中 Issue: 1 Pages: 48-54
  • DOI: 10.1111/j.1600-0528.2012.00706.x
  • Peer Reviewed
• [Presentation] 喪失歯数、歯磨き回数と脳血管疾患、虚血性心疾患リスクとの関連：歯科医師コホート研究 (2016)
  • Author(s): 若井建志、内藤真理子、内藤 徹、小島正彰、梅村長生、横田 誠、花田信弘、川村 孝
  • Organizer: 第26回日本疫学会学術総会
  • Place of Presentation: 米子コンベンションセンター（鳥取県米子市）
  • Year and Date: 2016-01-21
• [Presentation] The impact of oral health-related quality of life on total mortality (2015)
  • Author(s): Mariko Naito, Kenji Wakai, Toru Naito, Haruo Nakagaki, Nobuhiro Hanada, Takashi Kawamura
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち（名古屋市）
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] 歯牙喪失と肺炎による死亡の関連ー歯科医師集団のコホート研究による検討ー (2014)
  • Author(s): 須磨紫乃、若井建志、内藤真理子、内藤 徹、川村 孝、小島正彰、梅村長生、中垣晴男、横田 誠、花田信弘
  • Organizer: 第24回 日本疫学会学術総会
  • Place of Presentation: 日立システムズホール仙台（仙台市）
• [Presentation] 微量栄養素摂取と全死亡リスクの関連と、歯牙喪失と死亡リスクの関連への寄与：LEMONADE Study (2012)
  • Author(s): 若井 建志
  • Organizer: 第22回日本疫学会学術総会
  • Place of Presentation: 東京都千代田区
• [Presentation] The association between tooth loss and body mass index among Japanese adults: LEMONADE Study. (2011)
  • Author(s): 内藤 真理子
  • Organizer: 第60回日本口腔衛生学会・総会
  • Place of Presentation: 松戸市
• [Presentation] Association between smoking status and oral health-related quality of life among Japanese adults: LEMONADE study
  • Author(s): Mariko Naito, Kenji Wakai, Toru Naito, Haruo Nakagaki, Nobuhiro Hanada, Takashi Kawamura
  • Organizer: ISOQOL 19th Annual Conference
  • Place of Presentation: Budapest(Hungary)
• [Presentation] 喪失歯数と全死亡、肺炎死亡、虚血性心疾患・脳卒中罹患との関連ー歯科医師を対象としたコホート研究による検討ー
  • Author(s): 若井建志
  • Organizer: 日本老年歯科医学会 第24回学術大会(招待講演)
  • Place of Presentation: 大阪市
  • Invited
• [Remarks] LEMONADE Study
  • URL: http://www.med.nagoya-u.ac.jp/yobo/lemonade/lemonade/
• [Remarks] LEMONADE Study 歯科医師を対象とした歯と全身の健康、栄養との関連に関する研究
  • URL: http://www.med.nagoya-u.ac.jp/yobo/lemonade/lemonade/
• [Remarks] LEMONADE Study 歯科医師を対象とした歯と全身の健康、栄養との関連に関する研究
  • URL: http://www.med.nagoya-u.ac.jp/yobo/lemonade/lemonade/
• [Remarks]
  • URL: http://www.med.nagoya-u.ac.jp/yobo/lemonade/lemonade/index.html