Gene expression analysis on chromosome 17q25.1 in esophageal squamous cell carcinoma

• Project/Area Number: 23591937
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Iwate Medical University (2012-2013); Kyushu University (2011)
• Principal Investigator: IWAYA Takeshi 岩手医科大学, 医学部, 講師 (70405801)
• Co-Investigator(Kenkyū-buntansha): TANAKA Fumiaki 九州大学, 大学病院, 講師 (30332836)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 食道癌 / 遺伝子発現 / 遺伝子変異 / 変異 / 癌抑制遺伝子 / がんゲノム解析 / 発現解析

Research Abstract

Tylosis is an autosomal dominant skin disorder that is associated with the early onset of esophageal squamous cell carcinoma (ESCC) in several families.The tylosis esophageal cancer (TOC) gene locus has been mapped to chromosome 17q25.1 using linkage analyses of pedigrees of such families. This region is also frequently lost in sporadic ESCC. Therefore, genes involved in the development of esophageal cancer may exist in the TOC region on 17q25.1. Among many genes in the region, significant downregulation of ST6GALNAC1 expression in esophageal cancer tissues was confirmed. Frequent mutation, loss of heterozygosity, and hypermethylation in ST6GALNAC1 gene were observed. Our results suggest that downregulation of ST6GALNAC1 via hypermethylation and LOH are associated with the development of ESCC.

Research Products

• [Journal Article] A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines. (2014)
  • Author(s): Endo F, Nishizuka SS, Kume K, Ishida K, Katagiri H, Ishida K, Sato K, Iwaya T, Koeda K, Wakabayashi G.
  • Journal Title: PLoS One Volume: 27; 9 (2)
  • Peer Reviewed
• [Journal Article] Up-regulation of NEK2 by microRNA-128 methylation is associated with poor prognosis in colorectal cancer. (2014)
  • Author(s): Takahashi Y, Iwaya T, Sawada G, Kurashige J, Matsumura T, Uchi R, Ueo H, Takano Y, Eguchi H, Sudo T, Sugimachi K, Yamamoto H, Doki Y, Mori M, Mimori K.
  • Journal Title: Ann Surg Oncol. Volume: 21 (1) Issue: 1 Pages: 205-12
  • DOI: 10.1245/s10434-013-3264-3
  • Peer Reviewed
• [Journal Article] Contrasting expression patterns of histone mRNA and microRNA 760 in patients with gastric cancer (2013)
  • Author(s): Iwaya T, Fukagawa T, Suzuki Y, Nishizuka SS, Wakabayashi G, et al.
  • Journal Title: Clin Cancer Res. Volume: 19(23) Pages: 6438-49
  • Peer Reviewed
• [Journal Article] Up-regulation of NEK2 by MicroRNA-128 Methylation is Associated with Poor Prognosis in Colorectal Cancer (2013)
  • Author(s): Takahashi Y, Iwaya T, et al.
  • Journal Title: Ann Surg Oncol Volume: 21(1) Pages: 205-12
  • Peer Reviewed
• [Journal Article] Tumor-derived tenascin-C promotes the epithelial-mesenchymal transition in colorectal cancer cells (2013)
  • Author(s): Takahashi Y, Sawada G, Kurashige J, Matsumura T, Uchi R, Ueo H, Ishibashi M, Takano Y, Akiyoshi S, Iwaya T, Eguchi H, Sudo T, Sugimachi K, Yamamoto H, Doki Y, Mori M, Mimori K.
  • Journal Title: Anticancer Res. Volume: 33(5) Pages: 1927-34
  • Peer Reviewed
• [Journal Article] Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53 (2013)
  • Author(s): Ishibashi M, Iwaya T, Wakabayashi G, et al.
  • Journal Title: Ann Surg Oncol Volume: 20 Suppl 3 Pages: 537-44
  • Peer Reviewed
• [Journal Article] Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis (2013)
  • Author(s): Yokobori T, Iwaya T, et al.
  • Journal Title: Cancer Res. Volume: 73(7) Pages: 2059-69
  • Peer Reviewed
• [Journal Article] Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma (2013)
  • Author(s): Ishibashi M, Kogo R, Shibata K, Sawada G, Takahashi Y, Kurashige J, Akiyoshi S, Sasaki S, Iwaya T, Sudo T, Sugimachi K, Mimori K, Wakabayashi G.
  • Journal Title: Oncol Rep Volume: 29(3) Pages: 946-50
  • Peer Reviewed
• [Journal Article] Contrasting expression patterns of histone mRNA and microRNA 760 in patients with gastric cancer (2013)
  • Author(s): Iwaya T, Fukagawa T, Suzuki Y, Takahashi Y, Sawada G, Ishibashi M, Kurashige J, Sudo T, Tanaka F, Shibata K, Endo F, Katagiri H, Ishida K, Kume K, Nishizuka S, Iinuma H, Wakabayashi G, Mori M, Sasako M, Mimori K.
  • Journal Title: Clin Cancer Res Volume: 19 Issue: 23 Pages: 6438
  • DOI: 10.1158/1078-0432.ccr-12-3186
  • URL: https://pure.teikyo.jp/en/publications/3142205b-c0c7-4f67-9986-fb5d171f1348
  • Peer Reviewed
• [Journal Article] Tumor-derived tenascin-C promotes the epithelial-mesenchymal transition in colorectal cancer cells. (2013)
  • Author(s): Takahashi Y, Sawada G, Kurashige J, Matsumura T, Uchi R, Ueo H, Ishibashi M, Takano Y, Akiyoshi S, Iwaya T, Eguchi H, Sudo T, Sugimachi K, Yamamoto H, Doki Y, Mori M, Mimori K.
  • Journal Title: Anticancer Res. Volume: 33 (5) Pages: 1927-34
  • Peer Reviewed
• [Journal Article] Clinical significance of PICT1 in patients of hepatocellular carcinoma with wild-type TP53. (2013)
  • Author(s): Ishibashi M, Kogo R, Shibata K, Ueo H, Uchi R, Matsumura T, Takano Y, Sawada G, Takahashi Y, Mima K, Kurashige J, Akiyoshi S, Iwaya T, Eguchi H, Sudo T, Sugimachi K, Suzuki A, Wakabayashi G, Mori M, Mimori K.
  • Journal Title: Ann Surg Oncol. Volume: Supple 3: Issue: S3 Pages: 537-544
  • DOI: 10.1245/s10434-013-2958-x
  • Peer Reviewed
• [Journal Article] Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis. (2013)
  • Author(s): Yokobori T, Iinuma H, Shimamura T, Imoto S, Sugimachi K, Ishii H, Iwatsuki M, Ota D, Ohkuma M, Iwaya T, Nishida N, Kogo R, Sudo T, Tanaka F, Shibata K, Toh H, Sato T, Barnard GF, Fukagawa T, Yamamoto S, Nakanishi H, Sasaki S, Miyano S, Watanabe T, Kuwano H, Mimori K, Pantel K, Mori M.
  • Journal Title: Cancer Res Volume: 1; 73(7) Issue: 7 Pages: 2059-69
  • DOI: 10.1158/0008-5472.can-12-0326
  • Peer Reviewed
• [Journal Article] Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma. (2013)
  • Author(s): Ishibashi M, Kogo R, Shibata K, Sawada G, Takahashi Y, Kurashige J, Akiyoshi S, Sasaki S, Iwaya T, Sudo T, Sugimachi K, Mimori K, Wakabayashi G, Mori M.
  • Journal Title: Oncol Rep Volume: 29(3) Issue: 3 Pages: 946-50
  • DOI: 10.3892/or.2012.2219
  • Peer Reviewed
• [Journal Article] Usefulness of esophageal stenting for esophagorespiratory fistula with esophageal cancer (2012)
  • Author(s): Konosu M, Iwaya T, Wakabayashi G, et al.
  • Journal Title: Gan To Kagaku Ryoho Volume: 39(12) Pages: 1849-51
  • Peer Reviewed
• [Journal Article] Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway (2012)
  • Author(s): Iwaya T, Wakabayashi G, et al.
  • Journal Title: Carcinogenesis Volume: 33(12) Pages: 2391-7
  • Peer Reviewed
• [Journal Article] Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers (2012)
  • Author(s): Ishida K, Nishizuka SS, Iwaya T, Wakabayashi G, et al.
  • Journal Title: PLoS One Volume: 7(8)
  • Peer Reviewed
• [Journal Article] Expression of Mesenchymal Markers Vimentin and Fibronectin : The Clinical Significance in Esophageal Squamous Cell Carcinoma (2012)
  • Author(s): Sudo T, Iwaya T, et al.
  • Journal Title: Ann Surg Oncol Volume: 20 Suppl 3 Pages: 324-35
  • Peer Reviewed
• [Journal Article] Current topics in mutations in the cancer genome (2012)
  • Author(s): Iwaya T, Mimori K, Wakabayashi G.
  • Journal Title: Nihon Geka Gakkai Zasshi Volume: 113(2) Pages: 185-90
  • NAID: 110009425991
• [Journal Article] Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma (2012)
  • Author(s): Yokobori T, Iwaya T, et al.
  • Journal Title: Int J Oncol Volume: 41(1) Pages: 253-9
• [Journal Article] Doworegulation of associated with colorectal cancer progression via activation of mTOR signaling pathway. (2012)
  • Author(s): Iwaya T
  • Journal Title: Carcinogenesis Volume: 33 Issue: 12 Pages: 179-517
  • DOI: 10.1093/carcin/bgs288
  • Peer Reviewed
• [Journal Article] Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers. (2012)
  • Author(s): Ishida K, Nishiduka S, Chiba T, Ikeda M, Kume K, Endo F, Katagiri H, Matsuo T, Noda H, Iwaya T, Yamada N, Fujiwara H, Takahashi M, Itabashi T, Uesugi N,Maesawa C, Tamura G, Sugai T, Otsuka K, Koeda K, Wakabayashi G.
  • Journal Title: PLoS One Volume: 7(8) Issue: 8 Pages: e43236-e43236
  • DOI: 10.1371/journal.pone.0043236
  • Peer Reviewed
• [Journal Article] Expression of Mesenchymal Markers Vimentin and Fibronectin: The Clinical Significance in Esophageal Squamous Cell Carcinoma. (2012)
  • Author(s): Sudo T, Iwaya T, Nishida N, Sawada G, Takahashi Y, Ishibashi M, Shibata K, Fujita H, Shirouzu K, Mori M, Mimori K.
  • Journal Title: Ann Surg Oncol Volume: Epub Issue: S3 Pages: 324-335
  • DOI: 10.1245/s10434-012-2418-z
  • Peer Reviewed
• [Journal Article] Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma (2012)
  • Author(s): Mar ; 113(2): 204-9. 2. Yokobori T, Mimori K, Iwatsuki M, Ishii H, Tanaka F, Sato T, Toh H, Sudo T, Iwaya T, Tanaka Y, Onoyama I, Kuwano H, Nakayama KI, Mori M.
  • Journal Title: Int J Oncol Volume: 41(1) Pages: 253-9
  • DOI: 10.3892/ijo.2012.1436
  • Peer Reviewed
• [Journal Article] MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells (2012)
  • Author(s): Naohiro Nishida, Shinya Yamashita, Koshi Mimori, Tomoya Sudo, Fumiaki Tanaka, Kohei Shibata, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Masaki Mori
  • Journal Title: ANNALS OF SURGICAL ONCOLOGY Volume: (Epub) Issue: 9 Pages: 10-10
  • DOI: 10.1245/s10434-012-2246-1
  • Peer Reviewed
• [Journal Article] Review : Single nucleotide polymorphisms associated with the one ogenesis of colorectal cancer (2012)
  • Author(s): Mimori K, Tanaka F, Shibata K, Mori M
  • Journal Title: Surg Today Volume: 42 Issue: 3 Pages: 215-9
  • DOI: 10.1007/s00595-011-0038-z
  • Peer Reviewed
• [Journal Article] Histone deacetylase 1 expression in gastric cancer (2011)
  • Author(s): Sudo T, Mimori K, Nishida N, Kogo R, Iwaya T, et al.
  • Journal Title: Oncol Rep Volume: 26(4) Pages: 777-82
  • Peer Reviewed
• [Journal Article] Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models (2011)
  • Author(s): Matsuo T, Nishizuka SS, Iwaya T, Wakabayashi G.
  • Journal Title: BMC Res Notes Volume: 4 Pages: 140-140
  • Peer Reviewed
• [Journal Article] Histone deacetylase 1 expression in gastric cancer (2011)
  • Author(s): Sudo T, Mimori K, Nishida N, Kogo R, Iwaya T, Tanaka F, Shibata K, Fujita H, Shirouzu K, Mori M
  • Journal Title: Oncol Rep Volume: 26 Pages: 777-82
  • DOI: 10.3892/or.2011.1361
  • Peer Reviewed
• [Journal Article] Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers (2011)
  • Author(s): Kogo R, Shimamura T, Mimori K, Kawahara K, Imoto S, Sudo T, Tanaka F, Shibata K, Suzuki A, Komune S, Miyano S, Mori M
  • Journal Title: Cancer Res Volume: 71 Issue: 20 Pages: 6320-6
  • DOI: 10.1158/0008-5472.can-11-1021
  • Peer Reviewed
• [Journal Article] Clinicopathological and biological significance of CDC28 protein kinase regulatory subunit 2 overexpress ion in human gastric cancer (2011)
  • Author(s): Tanaka F, Matsuzaki S, Mimori K, Kita Y, Inoue H, Mori M
  • Journal Title: Int J Oncol Volume: 39 Pages: 361-72
  • DOI: 10.3892/ijo.2011.1056
  • Peer Reviewed
• [Journal Article] FBXO31 determines poor prognosis in esophageal squamous cell carcinoma (2011)
  • Author(s): Kogo R, Mimori K, Tanaka F, Komune S, Mori M
  • Journal Title: Int J Oncol Volume: 39 Pages: 155-9
  • DOI: 10.3892/ijo.2011.1018
  • Peer Reviewed
• [Journal Article] MicroRNA-125a-5p is an independent prognostic factor in gastric cancer, and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab (2011)
  • Author(s): Nishida N, Mimori K, Fabbri M, Yokobori T, Sudo T, Tanaka F, Shibata K, Ishii H, Doki Y, Mori M.]
  • Journal Title: Clin Cancer Res Volume: 17(9) Issue: 9 Pages: 2725-33
  • DOI: 10.1158/1078-0432.ccr-10-2132
  • Peer Reviewed
• [Presentation] MicroRNA 760 regulates gastric cancer progression by downregulation of histone mRNA expression (2014)
  • Author(s): Takeshi Iwaya, Takeo Fukagawa, Yutaka Suzuki, Tomoya Sudo, Kaoru Ishida, Kohei Kume, Satoshi Nishizuka, Hisae Iinuma, Masaki Mori, Mitsuru Sasako, Go Wakabayashi, Koshi Mimori
  • Organizer: アメリカ癌学会
  • Place of Presentation: サンディエゴ
• [Presentation] 胃癌患者骨髄/末梢血中遊離癌細胞・宿主細胞における遺伝子発現解析 (2013)
  • Author(s): 岩谷岳、深川剛生ら
  • Organizer: 第113回日本外科学会
• [Presentation] 大腸癌の予後に関わるlong non-coding RNAの解析 (2013)
  • Author(s): 岩谷岳、高橋佑典ら
  • Organizer: 第68回日本消化器外科学会
• [Presentation] Gene expression analysis of bone marrow cells in gastric cancer patients (2013)
  • Author(s): 岩谷岳、深川剛生ら
  • Organizer: 第72回日本癌学会
• [Presentation] 食道扁平上皮癌におけるNOTCH1遺伝子異常の解析 (2013)
  • Author(s): 岩谷岳、澤田元太ら
  • Organizer: 第67回日本食道学会
• [Presentation] 大腸癌の予後に関わるlong non-coding RNAの解析 (2013)
  • Author(s): 岩谷 岳、高橋佑典、澤田元太、石橋正久、 木村裕輔、秋山有史、鴻巣正史、 片桐弘勝、遠藤史隆、石田 馨、西塚 哲、 水野 大、佐々木章、肥田圭介、大塚幸喜、新田浩幸 森正樹、三森功士、若林剛
  • Organizer: 日本消化器外科学会
  • Place of Presentation: 宮崎
• [Presentation] Gene expression analysis of bone marrow cells in gastric cancer patients (2013)
  • Author(s): Takeshi Iwaya, Takeo Fukagawa, Yutaka Suzuki, Yusuke Takahashi, Genta Sawada, Kohei Kume, Satoshi Nishizuka, Hisae Iinuma, Go Wakabayashi, Mitsuru Sasako, Masaki Mori, Koshi Mimori
  • Organizer: 日本癌学会
  • Place of Presentation: 横浜
• [Presentation] 食道扁平上皮癌におけるNOTCH1遺伝子異常の解析 (2013)
  • Author(s): 岩谷 岳, 澤田 元太, 高橋 佑典, 鴻巣 正史, 秋山 有史, 木村 祐輔, 佐々木 章, 森 正樹, 三森 功士, 若林 剛
  • Organizer: 日本食道学会
  • Place of Presentation: 大阪
• [Presentation] 胃癌患者 骨髄/末梢血中 遊離癌細胞・宿主細胞における遺伝子発現解析 (2013)
  • Author(s): 岩谷 岳、 深川 剛生、 高橋 佑典、 澤田 元太、 石橋 正久、 藏重 淳二、 主藤 朝也、 遠藤 史隆、 片桐 弘勝、 石田 馨、 久米浩平、 西塚 哲、 鴻巣 正史、 秋山 有史、 木村 祐輔、 飯沼 久恵、 若林 剛、 森 正樹、 笹子 三満留、三森 功士
  • Organizer: 日本外科学会
  • Place of Presentation: 福岡
• [Presentation] Analysis of Notch1 gene in esophageal squamous cell carcinoma (2012)
  • Author(s): 岩谷岳、澤田元太ら
  • Organizer: 第66回日本癌学会学術
• [Presentation] Analysis of Notch1 gene in esophageal squamous cell carcinoma. (2012)
  • Author(s): Iwaya T, Sawada T, Takahashi Y, Ishibashi M, et al.
  • Organizer: 第71日本癌学会
  • Place of Presentation: 札幌
• [Presentation] 胃癌骨髄・原発巣におけるHistone mRNAおよびmiR-760発現変化 (2012)
  • Author(s): 岩谷岳, 三森功士, 西田尚弘, 古後龍之介, 赤木智徳, 高橋佑典, 澤田元太, 石橋正久, 柴田浩平, 田中文明, 主藤智也, 若林剛, 深川剛生, 笹子三津留, 森正樹.
  • Organizer: 第112回日本外科学会
  • Place of Presentation: 幕張
• [Presentation] 胃癌におけるHER2/neuを制御するマイクロRNAの臨床病理学的意義 (2012)
  • Author(s): 西田尚弘, 三森功士, 石橋正久, 高橋祐典, 澤田元太, 岩谷岳, 主藤朝也, 田中文明, 柴田浩平, 石井秀始, 森正樹.
  • Organizer: 第112回日本外科学会
  • Place of Presentation: 幕張
• [Presentation] 大腸癌におけるmicroRNA 144によるmTOR signaling pathwayの制御. (2012)
  • Author(s): 石丸神矢, 岩谷岳, 高橋佑典, 石橋正久, 澤田元太, 古後龍之介, 西田尚弘, 主藤朝也, 田中文明, 柴田浩平, 三森功士, 森正樹.
  • Organizer: 第112回日本外科学会
  • Place of Presentation: 幕張
• [Presentation] 胃癌症例におけるRFWD2の機能解析と臨床的意義について. (2012)
  • Author(s): 澤田 元太, 石橋 正久, 高橋 佑典, 岩谷 岳, 首藤 朝也, 田中文明, 柴田浩平, 三森功士, 森正樹, 土岐 祐一郎.
  • Organizer: 第67回日本消化器外科学会
  • Place of Presentation: 富山
• [Presentation] Analysis of all transcripts in TOC locus on chromosome 17q25.1 in esophageal squamous cell carcinoma (2011)
  • Author(s): 岩谷岳、三森功士ら
  • Organizer: 第65回日本癌学会学術
• [Presentation] miR-144によるmTOR制御と大腸癌の予後 (2011)
  • Author(s): 岩谷岳、横堀武彦、三森功士、主藤朝也、田中文明、柴田浩平、石丸神矢、古後龍之介、西田尚弘、森正樹
  • Organizer: 第111回日本外科学会定期学術集会
  • Place of Presentation: 紙上開催
• [Presentation] 大腸癌におけるmiR-144発現とmTOR制御に関する検討 (2011)
  • Author(s): 岩谷岳、横堀武彦、三森功士、西田尚弘、古後龍之介、石丸神矢、主藤朝也、田中文明、柴田浩平、森正樹
  • Organizer: 第20回日本がん転移学会学術集会
  • Place of Presentation: 浜松
• [Presentation] 胃癌原発巣・骨髄におけるhistone family 遺伝子発現の検討 (2011)
  • Author(s): 岩谷岳、三森功士、田中文明、柴田浩平、石丸神矢、西田尚弘、古後龍之介、主藤朝也、若林剛、森正樹
  • Organizer: 第66回日本消化器外科学会
  • Place of Presentation: 名古屋
• [Presentation] 胃癌骨髄・原発巣におけるHistone mRNAおよびmiR-760発現変化 (2011)
  • Author(s): 岩谷岳、三森功士、西田尚弘、古後龍之介、赤木智徳、高橋佑典、澤田元太、石橋正久、柴田浩平、田中文明、主藤朝也、森正樹
  • Organizer: 第6回GCOE理医連携リトリート（第14回九州大学生体防御医学研究所リトリート）
  • Place of Presentation: 阿蘇
• [Presentation] Histone mRNAs and miRNA-760 expression predict gastric cancer patient prognosis (2011)
  • Author(s): T Iwaya, K Mimori, N Nishida, R Kogo, K Shibata, F Tanaka, T Sudo, T Akagi, G Sawada, Y Takahashi, M Ishibashi, G Wakabayashi, M Mori.
  • Organizer: ISMRC
  • Place of Presentation: 大阪
• [Presentation] 食道扁平上皮癌における17q25.1 TOC locus上の全転写産物解析 (2011)
  • Author(s): 岩谷岳、三森功士、西田尚弘、古後龍之介、柴田浩平、田中文明、主藤朝也、澤田元太、高橋佑典、石橋正久、森正樹
  • Organizer: 第70回日本癌学会学術総会
  • Place of Presentation: 名古屋
• [Presentation] 早期・進行胃癌症例骨髄のWhole transcriptome解析による検討 (2011)
  • Author(s): 岩谷岳、深川剛生、三森功士、西田尚弘、古後龍之介、柴田浩平、田中文明、主藤朝也、赤木智徳、高橋佑典、澤田元太、石橋正久、笹子三津留、森正樹
  • Organizer: 第49回日本癌治療学会学術集会
  • Place of Presentation: 名古屋