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Human exercise tolerance and physiological anthropology

Research Project

Project/Area Number 24247046
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied anthropology
Research InstitutionKobe Design University

Principal Investigator

Koga Shunsaku  神戸芸術工科大学, 芸術工学部, 教授 (50125712)

Co-Investigator(Kenkyū-buntansha) 福場 良之  県立広島大学, 人間文化学部, 教授 (00165309)
福岡 義之  同志社大学, スポーツ健康科学部, 教授 (20265028)
近藤 徳彦  神戸大学, 人間発達環境学研究科, 教授 (70215458)
西保 岳  筑波大学, 体育系, 教授 (90237751)
Project Period (FY) 2012-10-31 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥43,940,000 (Direct Cost: ¥33,800,000、Indirect Cost: ¥10,140,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2014: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2013: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2012: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Keywords全身持久的運動能力 / 直立二足歩行 / 非定常状態 / 全身的協関 / 持久的運動能力を支える生理機能の全身的協関 / 運動・環境負荷刺激 / 非定常状態における有酸素運動能力の規定要因 / ヒトの持久的運動能力 / 酸素不足 / 統合生理機能 / 持久的運動能力 / 恒常性の維持 / 全身的な協関 / 酸素摂取動態 / 循環調節 / 体温調節機能 / 筋線維動員パターン / 時間分解近赤外分光装置 / 空間不均一性 / ヒトの全身持久的運動能力
Outline of Final Research Achievements

A key capability in hominid survival arose from the development of an erect, striding bipedal locomotion that could be sustained for prolonged periods and be readily responsive to rapid changes of velocity, i.e. the trait of “exercise tolerance”. We found that acquiring the ability to maintain whole-body integration of the physiological system (cardiopulmonary-, muscle metabolic-, and thermal functions) during exercise enabled human beings to evolve endurance work capacity, which is strongly correlated with health. In particular, systematic study on non-steady state responses to exercise (as seen in our daily life) is a key issue, because the non-steady state stimuli elicit the potentials of the body homeostasis and its polymorphism.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (39 results)

All 2016 2015 2014 2013 Other

All Int'l Joint Research (3 results) Journal Article (21 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 20 results,  Open Access: 2 results,  Acknowledgement Compliant: 15 results) Presentation (9 results) (of which Invited: 2 results) Book (1 results) Remarks (5 results)

  • [Int'l Joint Research] カンザス州立大学/カリフォルニア大学(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] カンザス州立大学(米国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] カリフォルニア大学ロスアンゼルス校(米国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Greater VO2peak is correlated with greater skeletal muscle deoxygenation amplitude and hemoglobin concentration within individual muscles during ramp-incremental cycle exercise.2016

    • Author(s)
      Okushima D, Poole DC, Barstow TJ, Rossiter HB, Kondo N, Bowen TS, Amano T, Koga S.
    • Journal Title

      Physiol Rep

      Volume: 4 Issue: 23 Pages: 1-11

    • DOI

      10.14814/phy2.13065

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Determination of the maximum rate of eccrine sweat glands' ion reabsorption using the galvanic skin conductance to local sweat rate relationship.2016

    • Author(s)
      Amano T, Gerrett N, Inoue Y, Nishiyasu T, Havenith G, and Kondo N.
    • Journal Title

      Eur J Appl Physiol

      Volume: 116 Pages: 281-290

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Influence of forearm muscle metaboreceptor activation on sweating and cutaneous vascular responses during dynamic exercise.2016

    • Author(s)
      Amano T, Ichinose M, Inoue Y, Nishiyasu T, Koga S, Kenny GP, and Kondo N.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 310 Pages: 1332-1339

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Effect of stride frequency on thermoregulatory responses during endurance running in distance runners.2016

    • Author(s)
      Amano T, Ishitobi M, Ogura Y, Inoue Y, Koga S, Nishiyasu T, and Kondo N.
    • Journal Title

      J Therm Biol

      Volume: 61 Pages: 61-66

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The spatial distribution of absolute skeletal muscle deoxygenation during ramp-incremental exercise is not influenced by hypoxia.2016

    • Author(s)
      Bowen TS, Koga S, Amano T, Kondo N, and Rossiter HB.
    • Journal Title

      Adv Exp Med Biol

      Volume: 876 Pages: 19-26

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Effects of meal ingestion on blood pressure and regional hemodynamic responses after exercise.2016

    • Author(s)
      Endo MY, Fujihara C, Miura A, Kashima H, and Fukuba Y.
    • Journal Title

      J Appl Physiol

      Volume: 120 Pages: 1343-1348

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Maximal workload but not peak oxygen uptake is decreased during immersed incremental exercise at cooler temperatures.2016

    • Author(s)
      Fujimoto T, Sasaki Y, Wakabayashi H, Sengoku Y, Tsubakimoto S, and Nishiyasu T.
    • Journal Title

      Eur J Appl Physiol

      Volume: 116 Pages: 1819-1827

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Sex differences in age-related changes on peripheral warm and cold innocuous thermal sensitivity.2016

    • Author(s)
      Inoue Y, Gerrett N, Ichinose-Kuwahara T, Umino Y, Kiuchi S, Amano T, Ueda H, Havenith G, and Kondo N.
    • Journal Title

      Physiol Behav

      Volume: 164 Pages: 86-92

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Walking economy at simulated high altitude in human healthy young male lowlanders.2016

    • Author(s)
      Horiuchi M, Handa Y, Abe D, and Fukuoka Y.
    • Journal Title

      Biol Open

      Volume: 5 Pages: 1408-1414

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Diurnal variation in the control of ventilation in response to rising body temperature during exercise in the heat.2016

    • Author(s)
      Tsuji B, Honda Y, Kondo N, and Nishiyasu T.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 311 Pages: 401-409

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Reduction of VO2 slow component by priming exercise: Novel mechanistic insights from time-resolved near-infrared spectroscopy2015

    • Author(s)
      Fukuoka Y, Poole DC, Barstow TJ, Kondo N, Nishiwaki M, Okushima D, Koga S.
    • Journal Title

      Physiol Rep

      Volume: 3 Issue: 6 Pages: 1-13

    • DOI

      10.14814/phy2.12432

    • NAID

      120006358590

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Muscle deoxygenation in the quadriceps during ramp incremental cycling: Deep vs. superficial heterogeneity.2015

    • Author(s)
      Okushima D, Poole DC, Rossiter HB, Barstow TJ, Kondo N, Ohmae E, and Koga S.
    • Journal Title

      J Appl Physiol

      Volume: 119 Issue: 11 Pages: 1313-1319

    • DOI

      10.1152/japplphysiol.00574.2015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Validation of a high-power time resolved near-infrared spectroscopy system for measurement of superficial and deep muscle deoxygenation during exercise.2015

    • Author(s)
      Koga S, Barstow TJ, Okushima D, Rossiter HB, Kondo N, Ohmae E, Poole DC.
    • Journal Title

      J Appl Physiol

      Volume: 未定 Issue: 11 Pages: 1435-1442

    • DOI

      10.1152/japplphysiol.01003.2014

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Changes in whole tissue heme concentration dissociates muscle deoxygenation from muscle oxygen extraction during passive head-up tilt.2015

    • Author(s)
      Adami A, Koga S, Kondo N, Cannon DT, Kowalchuk JM, Amano T, Rossiter HB.
    • Journal Title

      J Appl Physiol

      Volume: 未定 Issue: 9 Pages: 1091-1099

    • DOI

      10.1152/japplphysiol.00918.2014

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Muscle O2 extraction reserve during intense cycling is site-specific.2014

    • Author(s)
      Spencer MD, Amano T, Kondo N, Kowalchuk JM, Koga S.
    • Journal Title

      J Appl Physiol

      Volume: 117 Issue: 10 Pages: 1199-1206

    • DOI

      10.1152/japplphysiol.00060.2014

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Dynamic heterogeneity of exercising muscle blood flow and O2 utilization.2014

    • Author(s)
      Koga S, Rossiter HB, Heinonen I, Musch TI, Poole DC.
    • Journal Title

      Med Sci Sports Exer

      Volume: 46 Issue: 5 Pages: 860-876

    • DOI

      10.1249/mss.0000000000000178

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] ヒトの生理機能の全身的協関2013

    • Author(s)
      古賀 俊策、井上芳光、近藤徳彦
    • Journal Title

      日本生理人類学会誌

      Volume: 18 Pages: 187-194

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Slowed oxygen uptake kinetics in hypoxia correlate with the transient peak and reduced spatial distribution of absolute skeletal muscle deoxygenation.2013

    • Author(s)
      Bowen TS, Rossiter HB, Benson AP, Amano T, Kondo N, Kowalchuk JM, Koga S.
    • Journal Title

      Exp Physiol

      Volume: 98 Issue: 11 Pages: 1585-1596

    • DOI

      10.1113/expphysiol.2013.073270

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Muscle metaboreflex activation speeds the recovery of arterial blood pressure following acute hypotension in humans.2013

    • Author(s)
      Ichinose M, Watanabe K, Fujii N, Kondo N, Nishiyasu T.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 304 Pages: 1568-1575

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of sweating responses and peripheral sweat gland function during passive heating in sprinters.2013

    • Author(s)
      Amano T, Koga S, Inoue Y, Nishiyasu T, Kondo N.
    • Journal Title

      Eur J Appl Physiol.

      Volume: online Issue: 8 Pages: 2067-2075

    • DOI

      10.1007/s00421-013-2641-8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phosphocreatine resynthesis during recovery in different muscles of the exercising leg by 31P-nuclear magnetic resonance spectroscopy.2013

    • Author(s)
      Yoshida Y, Abe D, and Fukuoka Y.
    • Journal Title

      Scand J Med Sci Sports

      Volume: online Issue: 5 Pages: 313-319

    • DOI

      10.1111/sms.12081

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 活動筋における酸素不足の不均一性2015

    • Author(s)
      古賀 俊策
    • Organizer
      呼吸研究会
    • Place of Presentation
      ホテルアパローム紀の国
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Human adaptability to endurance exercise.2015

    • Author(s)
      Koga S, Okushima D, Poole DC.
    • Organizer
      日本生理人類学会・国際シンポジウム
    • Place of Presentation
      神戸大学発達科学部
    • Year and Date
      2015-03-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大腿筋表層部と深層部における運動強度と筋酸素動態との関連性2014

    • Author(s)
      奥島大、天野達郎、小田元樹、鈴木裕昭、大前悦子、近藤徳彦、古賀俊策
    • Organizer
      日本体力医学会
    • Place of Presentation
      長崎大学環境科学部
    • Year and Date
      2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Brachial and middle cerebral artery blood flows during sinusoidal leg cycling exercise.

    • Author(s)
      Y Fukuba, A Kondo, Y Kikugawa, M Y Endo, K Miura, N Hayashi, Y Fukuoka, S Koga.
    • Organizer
      Experimental Biology
    • Place of Presentation
      Boston (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of period of sinusoidal leg exercises on brachial and middle cerebral artery blood flows.

    • Author(s)
      Fukuba Y, K Miura, A Kondo, S Watanabe, MY Endo, H. Kashima, N. Hayashi, Y Fukuoka, S Koga.
    • Organizer
      日本生理学会大会
    • Place of Presentation
      鹿児島市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Characteristics of heat-induced hyperventilation in humans: implications for SBC?,Therapeutic Cranial Cooling and Selective Brain Cooling in Humans.

    • Author(s)
      T Nishiyasu
    • Organizer
      Experimental Biology Meeting
    • Place of Presentation
      Boston (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヒトの体温上昇時に見られる過換気反応

    • Author(s)
      辻 文、本田 靖、藤井直人、林 恵嗣、近藤徳彦、西保 岳
    • Organizer
      運動と体温の研究会
    • Place of Presentation
      立教大学池袋キャンパス
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 間欠的低酸素暴露下における中枢性呼吸調節の身体トレーニングの影響

    • Author(s)
      小又亮、堀田明日香、中村由紀、福岡義之
    • Organizer
      日本生理人類学会大会
    • Place of Presentation
      同志社大学京田辺キャンパス
    • Related Report
      2013 Annual Research Report
  • [Presentation] Circulatory dynamics during sinusoidal work rate forcing of bilateral knee extension exercise.

    • Author(s)
      Fukuba Y
    • Organizer
      日本生理学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Book] 人間科学の百科事典2014

    • Author(s)
      古賀 俊策
    • Total Pages
      800
    • Publisher
      丸善出版
    • Related Report
      2013 Annual Research Report
  • [Remarks]

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 神戸芸術工科大学 教員紹介研究業績

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 神戸芸術工科大学・大学院芸術工学研究科 教員サイト

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 神戸芸術工科大学・大学院芸術工学研究科 教員サイト

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 神戸芸術工科大学・大学院芸術工学研究科 教員サイト

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2012 Annual Research Report

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Published: 2012-11-27   Modified: 2022-01-28  

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