| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
We have investigated the use of polyvinyl alcohol hydrogels (PVA-H) for hemiarthroplasty. In this project, we studied materials and structures of the artificial bone and cartilage constituting artificial articular cartilages. For this aim, the technique which supplies biocompatibility and suitable cancellous structure to the engineering plastic (EP) as the artificial cancellous bone was studied. And also, tribological properties of PVA-H as the artificial cartilage versus natural articular cartilage was studied.
Deposition of titanium thin film to the EP surface imparted good osteoconduction and the proliferation and differentiation ability of osteoblasts to the EP bone. The wear resistance of the PVA-H mixed in only water (PVA-H/Water) which is developed in this project was compared with that of the PVA-H mixed in a conventional mixture of water and dimethyl sulfoxide (PVA/DMSO). The results indicated no significant difference in the wear resistance between PVA-H/DMSO and PVA-H/Water.
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