The research for Mg availability and dynamics during exercise
| Project/Area Number |
24500797
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Josai International University |
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Principal Investigator |
SAKAI Kensuke 城西国際大学, 薬学部, 准教授 (70406784)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 運動 / マグネシウム / TRPM7 / アシドーシス |
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| Outline of Final Research Achievements |
Exercise loading induced the increase in apparent Mg absorption and the expression of TRPM7, which is one of Mg-transporter in rat skeletal muscle. Especially in immediately after exercise, the expression of TRPM7 was elevated, it will be suggested that exercise-induced metabolic acidosis related to the expression of TRPM7. The expression pattern of TRPM7 in metabolic acidosis rat induced administrated 1.5% NH4Cl solution was different from in swimming exercised rat. Moreover other Mg-transporters, such as TRPM6 and CLDN16 were expressed in kidney and intestine. These results suggested that some Mg-transporters affect Mg dynamics in exercised rat.
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Report
(5 results)
Research Products
(4 results)
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[Presentation] Excess dietary Magnesium increases expression of TRPM7, but does not improve the amount of Magnesium in skeletal muscle of swimming exercised rats2014
Author(s)
Sakai, K., Shibata, R., Sugo, T., Shuto, E., Ohta, A.
Organizer
19th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE
Place of Presentation
Amsterdam, Netherlandｓ
Year and Date
2014-07-02 – 2014-07-05
Related Report
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