A study on biomarker of dementia of Lewy bodies with dopamine transporter imaging
| Project/Area Number |
24591733
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Nippon Medical School |
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Principal Investigator |
UEDA Satoshi 日本医科大学, 医学部, 講師 (80465294)
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| Co-Investigator(Kenkyū-buntansha) |
OKUBO Yoshiro 日本医科大学, 医学(系)研究科, 教授 (20213663)
TATENO Amane 日本医科大学, 医学部, 准教授 (50297917)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | DLB / DAT imaging / dopamine transportaer / レビー小体型認知症 / PETイメージング / ドパミントランスポーター / 国際研究者交流 / 国際情報交換 |
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| Outline of Final Research Achievements |
It does not appear easy to correctly diagnose patients with dementia with Lewy bodies (DLB). Although there is no definite diagnostic biomarkers for DLB, dopamine transporter (DAT) imaging using PET is considered possibly usuful as one of the strong biomarkers.
DAT imaging was conducted for patients with depression or parkinsonism, which DLB often accompanies. DAT imaging made it very easy to diagnose DLB among depressive or parkinsonic patients. These findings suggest that DAT imaging using PET may be a clinically useful biomarker for DLB.
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Report
(4 results)
Research Products
(15 results)
