| Project/Area Number |
24791104
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 甲状腺機能 / 早産児 / MCT8 / トランスサイレチン / 早産児一過性低サイロキシン血症 |
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| Outline of Final Research Achievements |
I investigated the expression of placental transthyretin and MCT8, and thyroid function of a preterm infants. In infants born below 28 weeks' gestation, transient low freeT4 without high TSH was observed, but it recovered naturally until 1 month. The expression of placental MCT8 mRNA was not significant by gestational week, or thyroid function of infant. The expression of placental transthyretin mRNA was decline according to gestational weeks, but the difference was not significant. There is a possibility that it reflect development of infant's thyroid function, but as the number of sample was not sufficient, further investigation will be need.
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