| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Proleg is abdominal appendage that develops in the larval abdomen of Lepidoptera, Mecoptera and Symphyta of Hymenoptera. The limited distribution of proleg-baring species raises the question whether prolegs are homologous structures or convergent traits. To address this issue we analyzed the molecular mechanisms underlying the proleg development. Dll expression is detected at their tips during embryonic development in Bombyx mori.
The development of appendages in abdominal segments are suppressed by the expression of Ubx, abd-A and Abd-B. Strange enough, the abd-A null mutant strain of Bombyx fail to develop prolegs . Moreover, knocking-down Dll made no effects on proleg development while gnathal appendages and thoracic legs are greatly reduced. Prolegs of Athalia rosae (Hymenoptera) are also segmented but lack crochets or any distal-most structures and no Dll expression was detected. These results suggest prolegs of Lepidoptera and Hymenoptera are of different origin.
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