Development of N(5)-Unsubstituted Neutral Flavin Catalysts with High Catalytic Activity towards Oxidation Reactions
| Project/Area Number |
25620086
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
IMADA Yasushi 徳島大学, ソシオテクノサイエンス研究部, 教授 (60183191)
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| Co-Investigator(Kenkyū-buntansha) |
MINAGAWA Keiji 徳島大学, 大学院ソシオテクノサイエンス研究部, 准教授 (70250959)
ARAKAWA Yukihiro 徳島大学, 大学院ソシオテクノサイエンス研究部, 助教 (70709203)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | フラビン触媒 / 酸化反応 / 反応場の構築 / 酸素酸化反応 / 担持型触媒 / 反応場 / 酸素添加反応 |
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| Outline of Final Research Achievements |
We have prepared novel N(5)-unsubstituted neutral flavin catalysts bearing effective reaction site as highly active and practical organocatalysts. These include (1) supramolecular flavin gel catalysts by self-assembly of flavin-containing low-molecular-weight gelators, (2) layered double hydroxide-supported flavin catalysts by intercalation of hydrotalcite by flavin carboxylic acid derivatives, and (3) polymer-supported flavin catalysts by co-polymerization of flavin-containing monomers such as flavin-containing styrene and flavin-containing methacrylate. These novel catalysts did not catalyze oxygenation of sulfides; however, they exihibit high catalytic activity towards aerobic hydrogenation reactions due to the reaction site introduced around the flavin molecules.
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Report
(3 results)
Research Products
(22 results)
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[Journal Article] Ring-expanding metathesis oligomerization of cyclic nitrones2014
Author(s)
Yasushi Imada, Chiaki Okita, Hiroki Maeda, Masayuki Kishimoto, Yoshinori Sugano, Hiroyuki Kaneshiro, Yuri Nishida, Soichiro Kawamorita, Naruyoshi Komiya, and Takeshi Naota
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Journal Title
European Journal of Organic Chemistry
Volume: nothing
Issue: 26
Pages: 5670-5674
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Presentation] カチオン性フラビン分子調製法の開発2015
Author(s)
大西崇裕, 幸田貴大, 荒川幸弘, 南川慶二, 今田泰嗣
Organizer
日本化学会第95春季年会
Place of Presentation
日本大学船橋キャンパス（千葉県船橋市）
Year and Date
2015-03-26 – 2015-03-29
Related Report
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[Presentation] 高分子固定化フラビン触媒の開発2014
Author(s)
荒川幸弘, 大西崇裕, 幸田貴大, 佐藤文彬, 南川慶二, 今田泰嗣
Organizer
第63 回高分 子討論会
Place of Presentation
長崎大学文教キャンパス（長崎県長崎市）
Year and Date
2014-09-24 – 2014-09-26
Related Report
Invited
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[Presentation] Flavin Catalysts Captured in Network Polymers2013
Author(s)
Fumiaki Sato, Yukihiro Arakawa, Keiji Minagawa and Yasushi Imada
Organizer
Advanced Molecular Transformations by Organocatalysts 1st International Conference & 6th Symposium on Organocatalysis
Place of Presentation
Otsu Pronce Hotel (Otsu, Shiga, Japan)
Related Report
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