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Development of oral probiotics using multi-bacteria

Research Project

Project/Area Number 25670886
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Periodontology
Research InstitutionThe University of Tokushima

Principal Investigator

FUJIWARA Natsumi  徳島大学, 大学院医歯薬学研究部, 助教 (50596913)

Co-Investigator(Kenkyū-buntansha) MURAKAMI Keiji  徳島大学, 大学院医歯薬学研究部, 助教 (10335804)
OZAKI Kazumi  徳島大学, 大学院医歯薬学研究部, 教授 (90214121)
MIYAKE Yoichiro  徳島大学, 大学院医歯薬学研究部, 教授 (80136093)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsプロバイオティクス / 歯周病 / Lactobacillus reuteri / 口臭
Outline of Final Research Achievements

We identified inhibitory effect of periodontopathic bacteria on Lactobacillus reuteri. Moreover, we identified that antimicrobial agents, reuterin produced from L. reuteri have antimicrobial and antibiofilm effects against periodontopathic bacteria.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (3 results)

  • [Journal Article] Significant increase of oral bacteria in the early pregnancy period in Japanese women2016

    • Author(s)
      Natsumi Fujiwara, Tsuruda Keiko, Iwamoto Yuko, Kato Fuminori, Odaki Teruko, Yamane Nobuko, Hori Yuriko, Harashima Yuka, Sakoda Ayako, Tagaya Akira, Komatsuzawa Hitoshi, Motoyuki Sugai and Noguchi Mayumi
    • Journal Title

      Journal of Investigative and Clinical Dentistry

      Volume: in press Issue: 1

    • DOI

      10.1111/jicd.12189

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 歯科衛生士教育におけるOSCE形式実技試験の環境構築2015

    • Author(s)
      湊 晶帆, 尾崎 和美, 藤原 奈津美, 中江 弘美, 薮内 さつき, 松山 美和
    • Journal Title

      日本歯科衛生教育学会雑誌

      Volume: 6 Pages: 30-39

    • NAID

      40020499003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] 歯学部学生の情動知能に対する高齢者交流学習の効果2015

    • Author(s)
      薮内 さつき, 中江 弘美, 日野出 大輔, 伊賀 弘起, 尾崎 和美, 白山 靖彦, 松山 美和, 吉岡 昌美, 柳沢 志津子, 藤原 奈津美, 渡辺 朱理, 土井 登紀子, 河野 文昭, 吉本 勝彦
    • Organizer
      日本歯科医学教育学会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Year and Date
      2015-07-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 歯科衛生士学生の自己教育力に関する実態について2015

    • Author(s)
      藤原 奈津美, 中江 弘美, 薮内 さつき, 尾崎 和美
    • Organizer
      日本歯科医学教育学会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Year and Date
      2015-07-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 全人的医療を支援する歯科衛生士教育としての病棟実習の取り組みとその効果2015

    • Author(s)
      中江 弘美, 藤原 奈津美, 伊賀 弘起, 吉岡 昌美, 日野出 大輔
    • Organizer
      日本歯科医学教育学会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Year and Date
      2015-07-10
    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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