Analysis of hemoglobin transport in Plasmodium falciparum
| Project/Area Number |
25860309
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Parasitology (including sanitary zoology)
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| Research Institution | Kobe University (2014)
Tottori University (2013) |
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Principal Investigator |
IRIKO HIDEYUKI 神戸大学, 保健学研究科, 准教授 (60346674)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | マラリア / ヘモグロビン輸送 / 寄生胞膜 / 熱帯熱マラリア原虫 |
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| Outline of Final Research Achievements |
To elucidate the molecular mechanism and membrane dynamics of hemoglobin transport, I focused in ETRAMP4 (Early Transcribed Protein 4), the membrane proteins expressed in trophozoite stage of Plasmodium falciparum. By immunoelectron microscopy, ETRAMP4 localized in parasitophorous vacuole membrane and uptake by cytostomes, hemoglobin transport vesicles.
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Report
(3 results)
Research Products
(5 results)
