The study to clarify the mechanism for the impairment and recovery of taste sensation corresponding with changes in breathing patterns
| Project/Area Number |
26293434
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
ONO Takashi 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30221857)
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| Co-Investigator(Kenkyū-buntansha) |
細道 純 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (00420258)
渡 一平 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (10431941)
誉田 栄一 徳島大学, 大学院医歯薬学研究部(歯学系), 教授 (30192321)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 口呼吸 / 味覚障害 / 濾紙ディスク法 / Functional MRI / 鼻閉モデル動物 / 舌味覚受容体 / functional MRI / 片側鼻閉モデルラット / 臨床調査 / ラット鼻閉モデル / 歯学 / 鼻呼吸障害 / 味覚受容器 / 舌 / ラット |
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| Outline of Final Research Achievements |
Habitual mouth breathing often cause impaired taste sensation. Although habitual mouth breathing is recognized to disturb the orofacial functional development, the relationship between habitual mouth breathing and taste disorders has not been investigated sufficiently. In the present study to clarify the link between habitual mouth breathing and taste disorders, we carried out the clinical survey targeting patients with mouth breathing. To clarify the mechanism for the impairment and recovery of taste sensation corresponding with changes in breathing patterns, animal studies were performed using the rodents with unilateral nasal obstruction. Data suggested that habitual mouth breathing poses a risk for taste deterioration with affecting taste receptors on the tongue.
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Report
(5 results)
Research Products
(8 results)
