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The study to clarify the mechanism for the impairment and recovery of taste sensation corresponding with changes in breathing patterns

Research Project

Project/Area Number 26293434
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Orthodontics/Pediatric dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

ONO Takashi  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30221857)

Co-Investigator(Kenkyū-buntansha) 細道 純  東京医科歯科大学, 大学院医歯学総合研究科, 講師 (00420258)
渡 一平  東京医科歯科大学, 大学院医歯学総合研究科, 助教 (10431941)
誉田 栄一  徳島大学, 大学院医歯薬学研究部(歯学系), 教授 (30192321)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords口呼吸 / 味覚障害 / 濾紙ディスク法 / Functional MRI / 鼻閉モデル動物 / 舌味覚受容体 / functional MRI / 片側鼻閉モデルラット / 臨床調査 / ラット鼻閉モデル / 歯学 / 鼻呼吸障害 / 味覚受容器 / 舌 / ラット
Outline of Final Research Achievements

Habitual mouth breathing often cause impaired taste sensation. Although habitual mouth breathing is recognized to disturb the orofacial functional development, the relationship between habitual mouth breathing and taste disorders has not been investigated sufficiently. In the present study to clarify the link between habitual mouth breathing and taste disorders, we carried out the clinical survey targeting patients with mouth breathing. To clarify the mechanism for the impairment and recovery of taste sensation corresponding with changes in breathing patterns, animal studies were performed using the rodents with unilateral nasal obstruction. Data suggested that habitual mouth breathing poses a risk for taste deterioration with affecting taste receptors on the tongue.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (8 results)

All 2018 2017 2016

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (4 results) (of which Int'l Joint Research: 1 results) Book (1 results)

  • [Journal Article] Influence of habitual mouth breathing on taste sensation2018

    • Author(s)
      Kimura-Ueda Kayo、Shimazaki Kazuo、Sugimoto Kumiko、Ono Takashi
    • Journal Title

      Orthodontic Waves

      Volume: 77 Issue: 1 Pages: 24-30

    • DOI

      10.1016/j.odw.2017.12.003

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of orthodontic appliance-derived artifacts on 3-T MRI movies2018

    • Author(s)
      Ozawa Erika、Honda Ei-ichi、Parakonthun Kulthida Nunthayanon、Ohmori Hiroko、Shimazaki Kazuo、Kurabayashi Tohru、Ono Takashi
    • Journal Title

      Progress in Orthodontics

      Volume: 19 Issue: 1 Pages: 7-7

    • DOI

      10.1186/s40510-018-0204-6

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unilateral nasal obstruction induces degeneration of fungiform and circumvallate papillae in rats2018

    • Author(s)
      Hsu Jui-Chin、Watari Ippei、Funaki Yukiha、Kokai Satoshi、Ono Takashi
    • Journal Title

      Journal of the Formosan Medical Association

      Volume: 117 Issue: 3 Pages: 220-226

    • DOI

      10.1016/j.jfma.2017.04.013

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 習慣的口呼吸が味覚感受性に与える影響について2017

    • Author(s)
      木村佳世, 島崎一夫, 杉本久美子, 小野卓史
    • Organizer
      第82回口腔病学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 磁気共鳴脳血管画像診断における矯正歯科装置の影響2017

    • Author(s)
      小澤英里佳, 小澤常徳, 大森浩子, 島崎一夫, 倉林亨, 小野卓史
    • Organizer
      第76回日本矯正歯科学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 鼻呼吸障害が味覚に与える影響について2017

    • Author(s)
      任尓舒, 渡一平, 許瑞瑾, 井上カタジアンナ, 窪野真理子, 渡部徹郎, 小野卓史
    • Organizer
      第76回日本矯正歯科学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Influences of Habitual Mouth-breathing on Taste Sensation2016

    • Author(s)
      Kayo Kimura, Kazuo Shimazaki, Kumiko Sugimoto, Takashi Ono
    • Organizer
      94th general session and exhibition of the IADR
    • Place of Presentation
      ソウル(大韓民国)
    • Year and Date
      2016-06-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Book] 矯正歯科のための重要16キーワード ベスト320論文2017

    • Author(s)
      小野卓史、小海 暁、細道 純、石田雄之、臼見莉沙、沖原秀政、上杉俊輔、池田侑平、今村俊博
    • Total Pages
      204
    • Publisher
      クインテッセンス出版
    • ISBN
      4781205798
    • Related Report
      2017 Annual Research Report

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Published: 2014-04-04   Modified: 2019-03-29  

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