Longitudinal effects of high-intensity interval training (HIIT) on fat distribution, metabolic parameters and composition of free fatty acids
| Project/Area Number |
26350905
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Keio University |
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Principal Investigator |
KAWAI TOSHIHIDE 慶應義塾大学, 医学部(信濃町), 講師(非常勤) (10276230)
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| Research Collaborator |
AZUMA Koichiro
FUJII Chikako
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 内臓脂肪 / 脂肪酸分画 / リノール酸 / インスリン抵抗性 / 高強度運動 / 運動療法 / 体脂肪分布 |
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| Outline of Final Research Achievements |
We evaluated the relationships between the composition of free fatty acids (FFA) and metabolic parameters, including body fat distribution. The study subjects were 111 Japanese (54 men/ 57 women) who underwent 75g-OGTT. 24 fractions of serum FFA, lipids, and fat distribution by CT scanning were measured. Our data suggest that linoleic acid level was inversely correlated with accumulation of visceral fat in relation to a reduction of insulin resistance. We evaluated an original treadmill protocol “KEIO-SENIOR” which we developed for patients with diabetes who need life-style modification. The study subjects were 50 Japanese. Based on the results, we made an exercise prescription. After 6 months, we found significant weight reduction, decreased blood pressures and improvement of glycemic control. We showed that a combined leg-cycling high-intensity interval training (HIIT) and arm-cranking-HIIT program improves aerobic capacity and muscle hypertrophy in 12 healthy male subjects.
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] Relationships between composition of major fatty acids and fat distribution, and insulin resistance in Japanese2017
Author(s)
Fujii C, Kawai T, Azuma K, Oguma Y, Katsukawa F, Hirose H, Tanaka K, Meguro S, Matsumoto H, Itoh H
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Journal Title
J Diabetes Res
Volume: ID1567467
Pages: 1-9
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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