Longitudinal effects of high-intensity interval training (HIIT) on fat distribution, metabolic parameters and composition of free fatty acids

2016 Fiscal Year Final Research Report

• Project/Area Number: 26350905
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied health science
• Research Institution: Keio University
• Principal Investigator: KAWAI TOSHIHIDE 慶應義塾大学, 医学部(信濃町), 講師(非常勤) (10276230)
• Research Collaborator: AZUMA Koichiro ; FUJII Chikako
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 内臓脂肪 / 脂肪酸分画 / リノール酸 / インスリン抵抗性 / 高強度運動

Outline of Final Research Achievements

We evaluated the relationships between the composition of free fatty acids (FFA) and metabolic parameters, including body fat distribution. The study subjects were 111 Japanese (54 men/ 57 women) who underwent 75g-OGTT. 24 fractions of serum FFA, lipids, and fat distribution by CT scanning were measured. Our data suggest that linoleic acid level was inversely correlated with accumulation of visceral fat in relation to a reduction of insulin resistance. We evaluated an original treadmill protocol “KEIO-SENIOR” which we developed for patients with diabetes who need life-style modification. The study subjects were 50 Japanese. Based on the results, we made an exercise prescription. After 6 months, we found significant weight reduction, decreased blood pressures and improvement of glycemic control. We showed that a combined leg-cycling high-intensity interval training (HIIT) and arm-cranking-HIIT program improves aerobic capacity and muscle hypertrophy in 12 healthy male subjects.

Free Research Field

複合領域