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The effect of glycative stress on functions and signal transduction networks in skeletal muscle

Research Project

Project/Area Number 26560371
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionToyohashi Sozo University

Principal Investigator

EGAWA Tatsuro  豊橋創造大学, 健康科学研究科, 協力研究員 (00722331)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords糖化 / AGEs / 骨格筋 / リン酸化 / タンパク質合成 / タンパク質分解 / 筋形成 / 筋成長 / 筋分化 / 終末糖化産物 / 糖化ストレス / 筋張力 / 逆相タンパク質アレイ / シグナル伝達
Outline of Final Research Achievements

The purpose of this study was to investigate the effect of glycative stress on skeletal muscle functions. The treatment of advanced glycation end products (AGEs) in C2C12 skeletal muscle cells affected phosphorylated state of proteins associated with glucose metabolism and/or muscle development. In addition, the consumption of diets containing high AGEs suppressed skeletal muscle growth via inhibiting muscle development and protein synthesis in mice. These data suggest that glycative stress deteriorates skeletal muscle functions.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (64 results)

All 2017 2016 2015 2014 Other

All Journal Article (8 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 7 results,  Open Access: 6 results,  Acknowledgement Compliant: 3 results) Presentation (50 results) (of which Int'l Joint Research: 9 results,  Invited: 2 results) Book (3 results) Remarks (3 results)

  • [Journal Article] Potential involvement of dietary advanced glycation end products in impairment of skeletal muscle growth and muscle contractile function in mice.2017

    • Author(s)
      Egawa T, Tsuda S, Goto A, Yokoyama S, Ohno Y, Goto K, Hayashi T.
    • Journal Title

      Br J Nutr.

      Volume: 117 Issue: 1 Pages: 21-29

    • DOI

      10.1017/s0007114516004591

    • NAID

      120006305928

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Caffeine affects myotube size as well as regulates protein degradation and protein synthesis pathways in C2C12 skeletal muscle cells.2016

    • Author(s)
      Egawa T, Ohno Y, Goto A, Sugiura T, Ohira Y, Yoshioka T, Hayashi T, Goto K.
    • Journal Title

      J Caffeine Res.

      Volume: 6 Issue: 2 Pages: 88-96

    • DOI

      10.1089/jcr.2015.0034

    • NAID

      120006305927

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Heat shock transcription factor 1-associated expression of slow myosin heavy chain in mouse soleus muscle in response to unloading with or without reloading2016

    • Author(s)
      Yokoyama S, Ohno Y, Egawa T, Yasuhara K, Nakai A, Sugiura T, Ohira Y, Yoshioka T, Okita M, Origuchi T, Goto K
    • Journal Title

      Acta Physiol (Oxf)

      Volume: 217 Issue: 4 Pages: 325-337

    • DOI

      10.1111/apha.12692

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Caffeine and contraction synergistically stimulate 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle2015

    • Author(s)
      Tsuda S, Egawa T, Kitani K, Oshima R, Ma X, Hayashi T
    • Journal Title

      Physiol Rep

      Volume: 3 Issue: 10 Pages: e12592-e12592

    • DOI

      10.14814/phy2.12592

    • NAID

      120006767890

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Heat stress acutely activates insulin-independent glucose transport and 5'-AMP-activated protein kinase prior to an increase in HSP72 in rat skeletal muscle2015

    • Author(s)
      Goto A, Egawa T, Sakon I, Oshima R, Ito K, Serizawa Y, Sekine K, Tsuda S, Goto K, Hayashi T
    • Journal Title

      Physiol Rep

      Volume: 3 Issue: 11 Pages: e12601-e12601

    • DOI

      10.14814/phy2.12601

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Deficiency of heat shock transcription factor 1 suppresses heat stress-associated increase in slow soleus muscle mass of mice2015

    • Author(s)
      Ohno Y, Egawa T, Yokoyama S, Nakai A, Sugiura T, Ohira Y, Yoshioka T, Goto K
    • Journal Title

      Acta Physiol (Oxf)

      Volume: 215 Issue: 4 Pages: 191-203

    • DOI

      10.1111/apha.12600

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Evidence for organic cation transporter-mediated metformin transport and 5'-adenosine monophosphate-activated protein kinase activation in rat skeletal muscles2014

    • Author(s)
      Oshima R, Yamada M, Kurogi K, Ogino Y, Serizawa Y, Tsuda S, Ma X, Egawa T, Hayashi T
    • Journal Title

      Metabolism

      Volume: 64 Issue: 2 Pages: 296-304

    • DOI

      10.1016/j.metabol.2014.10.037

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Regulation mechanism of caffeine on glucose transport and upstream signaling pathways in skeletal muscle2014

    • Author(s)
      江川達郎、後藤勝正、後藤亜由美、大野善隆、林達也
    • Journal Title

      デサントスポーツ科学

      Volume: 35 Pages: 131-139

    • Related Report
      2014 Research-status Report
  • [Presentation] 終末糖化産物AGEs摂取はマウス骨格筋成長を抑制する2017

    • Author(s)
      江川達郎、津田諭志、後藤亜由美、横山真吾、大野善隆、後藤勝正、林達也
    • Organizer
      第71回日本栄養・食糧学会大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2017-05-19
    • Related Report
      2016 Annual Research Report
  • [Presentation] Short-term heat stress stimulates glycogen and protein metabolism in rat skeletal muscle2016

    • Author(s)
      Goto A, Egawa T, Sekine K, Sakon I, Oshima R, Tsuda S, Hayashi T
    • Organizer
      APS Intersociety Meeting: The Integrative Biology of Exercise VII
    • Place of Presentation
      Phoenix, Arizona, USA
    • Year and Date
      2016-11-02
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 代謝センサーAMPKの骨格筋萎縮・肥大調節機構2016

    • Author(s)
      江川達郎、林達也、後藤勝正
    • Organizer
      第62回日本宇宙航空環境医学会大会日本宇宙生物科学会第30回大会合同大会
    • Place of Presentation
      愛知医科大学(愛知県長久手市)
    • Year and Date
      2016-10-13
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 短時間の熱刺激が骨格筋タンパク質ならびにグリコーゲン代謝に及ぼす影響2016

    • Author(s)
      後藤亜由美、江川達郎、関根圭一、大島里詠子、左近一翔、津田諭志、林達也
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県民情報交流センター(アイーナ)(岩手県盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 骨格筋量の調整における乳酸受容体の役割2016

    • Author(s)
      大野善隆、横山真吾、江川達郎、杉浦崇夫、大平充宣、吉岡利忠、後藤勝正
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県民情報交流センター(アイーナ)(岩手県盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] MBLN1発現低下がマウス骨格筋細胞のミオシン重鎖mRNA発現に及ぼす影響2016

    • Author(s)
      横山真吾、大野善隆、江川達郎、中村文音、後藤勝正
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県民情報交流センター(アイーナ)(岩手県盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 高濃度アディポネクチンが骨格筋細胞の分化に及ぼす影響2016

    • Author(s)
      伊藤理香、横山真吾、大野善隆、江川達郎、永富良一、宮田浩文、後藤勝正
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県民情報交流センター(アイーナ)(岩手県盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 食事性AGEsがマウス骨格筋の成長に及ぼす影響2016

    • Author(s)
      江川達郎、津田諭志、後藤亜由美、横山真吾、大野善隆、後藤勝正、林達也
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県民情報交流センター(アイーナ)(岩手県盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 短時間の熱刺激が骨格筋糖代謝に与える影響2016

    • Author(s)
      後藤亜由美、江川達郎、関根圭一、左近一翔、大島里詠子、津田諭志、林達也
    • Organizer
      第51回日本理学療法学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 加齢性の骨格筋萎縮に伴う選択的スプライシング因子muscleblind-like1の変化2016

    • Author(s)
      中村文音、大野善隆、横山真吾、江川達郎、鈴木美穂、鬼村知子、伊藤理香、後藤勝正
    • Organizer
      第51回日本理学療法学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 短時間の熱刺激が骨格筋糖輸送活性ならびに5'-AMP-activated protein kinase(AMPK)に与える影響2016

    • Author(s)
      後藤亜由美、江川達郎、左近一翔、関根圭一、大島里詠子、津田諭志、林達也
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-05-19
    • Related Report
      2016 Annual Research Report
  • [Presentation] 終末糖化産物AGEs蓄積に伴う骨格筋リン酸化タンパク質動態の網羅的解析2016

    • Author(s)
      江川達郎、大野善隆、横山真吾、後藤亜由美、津田諭志、林達也、後藤勝正
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-05-19
    • Related Report
      2016 Annual Research Report
  • [Presentation] Possible role of metabolic sensor in muscle adaptations under microgravity environment2016

    • Author(s)
      Egawa T, Hayashi T, Goto K
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-22
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 高AGEs含有食の長期摂取によるマウス骨格筋量および筋力発揮への影響2016

    • Author(s)
      江川達郎、津田諭志、後藤亜由美、後藤勝正、林達也
    • Organizer
      第55回日本栄養・食糧学会近畿支部大会
    • Place of Presentation
      帝塚山学院大学(大阪府大阪狭山市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] AMPK活性化剤は運動療法による代謝改善効果をどこまで模倣できるか?-メタボローム分析によるAMPK仮説の検証-2015

    • Author(s)
      宮本理人、江川達郎、大島里詠子、黒木英梨子、土屋浩一郎、林達也
    • Organizer
      第128回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2015-11-20
    • Related Report
      2015 Research-status Report
  • [Presentation] Caffeine activates 5'-AMP-activated protein kinase and insulin-independent glucose transport during contractionwith mitigated fatigue in rat skeletal muscle2015

    • Author(s)
      Tsuda S, Egawa T, Kitani K, Oshima R, Ma X, Hayashi T
    • Organizer
      The 8th Asia-Oceania Conference on Obesity (AOCO2015)
    • Place of Presentation
      名古屋国際会議場)愛知県名古屋市)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Possible mechanism of caffeine-induced acute impairment of insulin sensitivity in rat skeletal muscle2015

    • Author(s)
      Egawa T, Tsuda S, Ma X, Hamada T, Goto K, Hayashi T
    • Organizer
      The 8th Asia-Oceania Conference on Obesity (AOCO2015)
    • Place of Presentation
      名古屋国際会議場)愛知県名古屋市)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Acute heat stress (HS) stimulates 5’adenosine monophosphate-activated protein kinase (AMPK) and insulin-independent glucose transport in rat skeletal muscle2015

    • Author(s)
      Goto A, Sakon I, Oshima R, Sekine K, Tsuda S, Egawa T, Hayashi T
    • Organizer
      The 8th Asia-Oceania Conference on Obesity (AOCO2015)
    • Place of Presentation
      名古屋国際会議場)愛知県名古屋市)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] AMPKが廃用性筋萎縮に伴う骨格筋micro RNA発現変化に与える影響2015

    • Author(s)
      江川達郎、後藤亜由美、大野善隆、横山真吾、林達也、後藤勝正
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 熱ショック転写因子1はmicroRNAを介して遅筋型ミオシン重鎖発現を制御する2015

    • Author(s)
      横山真吾、大野善隆、 江川達郎、杉浦崇夫、大平充宣、吉岡利忠、後藤勝正
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 骨格筋におけるアクチン結合タンパク質filamin Cの発現応答2015

    • Author(s)
      鬼村知子、横山真吾、生田旭洋、宅和美穂、江川達郎、大野善隆、池谷直美、伊藤理香、比嘉正輝、中村文音、後藤勝正
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 骨格筋萎縮と再成長に伴うmuscleblind-like 1の挙動2015

    • Author(s)
      中村文音、後藤勝正、大野善隆、横山真吾、江川達郎、生田旭洋、宅和美穂、伊藤理香、鬼村知子
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 骨格筋細胞の分化におけるアディポネクチン-アディポネクチン受容体1シグナルの関与2015

    • Author(s)
      伊藤理香、横山真吾、大野善隆、 江川達郎、宅和美穂、生田旭洋、杉浦崇夫、大平充宣、吉岡利忠、後藤勝正
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 急性的な熱刺激が骨格筋糖代謝ならびにAMPK動態に及ぼす影響2015

    • Author(s)
      後藤亜由美、左近一翔、大島里詠子、関根圭一、津田諭志、江川達郎、林達也
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] カフェインは収縮時骨格筋の疲労を軽減しAMPキナーゼ活性化を増強する2015

    • Author(s)
      津田諭志、江川達郎、大島里詠子、木谷一登、林達也
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館(和歌山県和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] Caffeine increases contraction-stimulated 5’-AMP-activated protein kinase activity and insulin-independent glucose transport in rat skeletal muscle2015

    • Author(s)
      Tsuda S, Egawa T, Kitani K, Oshima R, Ma X, Hayashi T
    • Organizer
      2nd Congress, International Academy of Sportology
    • Place of Presentation
      順天堂大学(東京都文京区)
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] AMPK-mediated regulation of protein degradation systems in unloaded mouse skeletal muscle2015

    • Author(s)
      Egawa T, Goto A, Ohno Y, Yokoyama S, Suzuki-Takuwa M, Ikuta A, Hayashi T, Goto K
    • Organizer
      2nd Congress, International Academy of Sportology
    • Place of Presentation
      順天堂大学(東京都文京区)
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Typical responses of nuclear shape and distribution in skeletal muscle fibers in senescence-accelerated mice2015

    • Author(s)
      Goto K, Yokoyama S, Suzuki M, Ikuta A, Ito R, Ikegaya N, Onimura T, Higa M, Egawa T, Ohno Y, Sugiura T, Ohira Y, Yoshioka T
    • Organizer
      International Conference on Biochemistry of Exercise (IBEC 2015)
    • Place of Presentation
      Sao Pulo, Brazil
    • Year and Date
      2015-09-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] AMPK活性化剤はどこまで運動療法の代謝改善効果を模倣できるか?-メタボローム分析による検証-2015

    • Author(s)
      宮本理人、江川達郎、大島里詠子、黒木英梨子、土屋浩一郎、林達也
    • Organizer
      次世代を担う創薬・医療薬理シンポジウム2015
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
  • [Presentation] Acute heat stress activates glucose transport and 5’adenosine monophosphate-activated protein kinase in rat skeletal muscle2015

    • Author(s)
      Goto A, Sakon I, Oshima R, Egawa T, Serizawa S, Tsuda S, Hayashi T
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2015-06-05
    • Related Report
      2015 Research-status Report
  • [Presentation] Involvment of AMPK on hindlimb unloading-induced adaptation of muscle mass in mice2015

    • Author(s)
      Egawa T, Goto A, Ohno Y, Yokoyama S, Suzuki-Takuwa M, Ikuta A, Hayashi T, Sugiura T, Ohira Y, Yoshioka T, Goto K
    • Organizer
      The 11th World Congress of the International Society for Adaptive Medicine (ISAM 2015)
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2015-05-27
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] メタボローム解析による、骨格筋収縮時のメタボローム変化におけるAMPKの意義2015

    • Author(s)
      宮本理人、江川達郎、大島里詠子、黒木英梨子、土屋浩一郎、林達也
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Research-status Report
  • [Presentation] Caffeine stimulates protein degradation systems and inhibits muscle hypertrophy in skeletal muscle cells. 12th Asian Congress of Nutrition2015

    • Author(s)
      Egawa T, Ohno Y, Yokoyama S, Suzuki-Takuwa M, Ikuta A, Goto A, Goto K
    • Organizer
      12th Asian Congress of Nutrition
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-05-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] AMPK活性抑制がマウス骨格筋の廃用性萎縮の進行に及ぼす影響2015

    • Author(s)
      江川達郎、大野善隆、後藤亜由美、横山真吾、生田旭洋、鈴木美穂、林達也、後藤勝正
    • Organizer
      第19回日本体力医学会東海地方会学術集会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] コーヒー成分(カフェイン・カフェ酸・クロロゲン酸)が収縮時の骨格筋糖輸送活性および関連シグナルに及ぼす影響2014

    • Author(s)
      津田諭志、江川達郎、大島里詠子、木谷一登、林達也
    • Organizer
      第12回日本機能性食品医用学会総会
    • Place of Presentation
      京都国際会館(京都市)
    • Year and Date
      2014-12-13 – 2014-12-14
    • Related Report
      2014 Research-status Report
  • [Presentation] Responses of circulating microRNAs to unloading-associated atrophy and reloading-induced regrowth of mouse hindlimb skeletal muscle2014

    • Author(s)
      Suzuki M, Egawa T, Ikuta A, Goto A, Yokoyama S, Ohno Y, Sugiura T, Ohira Y, Yoshioka T, Goto K
    • Organizer
      2014 Australian Physiological Society (AuPS) Meeting
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2014-11-30 – 2014-12-03
    • Related Report
      2014 Research-status Report
  • [Presentation] Heat stress acutely stimulates insulin-independent glucose transport and 5′ adenosine monophosphate -activated protein kinase in rat skeletal muscle2014

    • Author(s)
      Goto A, Sakon I, Oshima R, Egawa T, Serizawa S, Tsuda S, Hayashi T
    • Organizer
      2014 Australian Physiological Society (AuPS) Meeting
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2014-11-30 – 2014-12-03
    • Related Report
      2014 Research-status Report
  • [Presentation] AICAR stimulation mimics metabolomic effects of electrical contraction in isolated rat epitrochlearis muscle2014

    • Author(s)
      Miyamoto L, Egawa T, Oshima R, Kurogi E, Tsuchiya K, Hayashi T
    • Organizer
      10th International Diabetes Federation-Western Pacific Region Congress and the 6th AASD Scientific Meeting
    • Place of Presentation
      Singapore, Singapore
    • Year and Date
      2014-11-21 – 2014-11-24
    • Related Report
      2014 Research-status Report
  • [Presentation] 骨格筋収縮時のメタボローム変化におけるAMPKの意義2014

    • Author(s)
      宮本理人、江川達郎、大島里詠子、黒木英梨子、土屋浩一郎、林達也
    • Organizer
      第35回日本肥満学会
    • Place of Presentation
      フェニックスシーガイアリゾート コンベンションセンター(宮崎市)
    • Year and Date
      2014-10-24 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] Expressions of angiopoietin 1/Tie-2 expressions in unloading-associated atrophied mouse skeletal muscles2014

    • Author(s)
      Ikuta A, Suzuki M, Egawa T, Ohno Y, Sugiura T, Ohira Y, Yoshioka T, Goto K
    • Organizer
      The 30th Annual Meeting of the American Society for Gravitational and Space Research (ASGSR)
    • Place of Presentation
      Pasadena, California, USA
    • Year and Date
      2014-10-22 – 2014-10-26
    • Related Report
      2014 Research-status Report
  • [Presentation] コーヒー含有成分が筋収縮時の骨格筋AMPキナーゼ活性化に及ぼす影響2014

    • Author(s)
      津田諭志、江川達郎、大島里詠子、木谷一登、林達也
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 骨格筋への急性的な熱刺激がAMPKならびに代謝変化に与える影響2014

    • Author(s)
      後藤亜由美、左近一翔、大島里詠子、江川達郎、芹澤康浩、津田諭志、林達也
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] ラット骨格筋におけるレスベラトロールのグリコーゲン合成及び蛋白質合成の抑制2014

    • Author(s)
      大島里詠子、荻野陽平、黒木英梨子、津田諭志、馬嘯、江川達郎、林達也
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 骨格筋細胞由来アディポネクチンが筋細胞の分化に及ぼす影響2014

    • Author(s)
      伊藤理香、横山真吾、大野善隆、江川達郎、鈴木美穂、生田旭洋、杉浦崇夫、大平充宣、吉岡利忠、後藤勝正
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] マウス骨格筋量の変化に伴う血中マイクロRNAの応答2014

    • Author(s)
      鈴木美穂、江川達郎、生田旭洋、後藤亜由美、横山真吾、大野善隆、吉岡利忠、大平充宣、後藤勝正
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] マウスヒラメ筋の筋線維タイプ構成における熱ショック転写因子12014

    • Author(s)
      横山真吾、大野善隆、江川達郎、生田旭洋、鈴木美穂、後藤勝正
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] AMPKが後肢懸垂処置によるマウスヒラメ筋の廃用性萎縮におよぼす影響2014

    • Author(s)
      江川達郎、後藤亜由美、大野善隆、横山真吾、生田旭洋、鈴木美穂、後藤勝正
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] Inhibition of C2C12 myotube hypertrophy via heat shock protein-dependent 5’AMP-activated protein kinase activation2014

    • Author(s)
      Goto K, Egawa T, Sugiura T,Ohira Y, Yoshioka T
    • Organizer
      FASEB Scientific Research Conferences 2014 Skeletal Muscle Satellite & Stem Cells
    • Place of Presentation
      Steamboat Springs, Colorado, USA
    • Year and Date
      2014-07-20 – 2014-07-25
    • Related Report
      2014 Research-status Report
  • [Presentation] カフェインは収縮時骨格筋AMPキナーゼ活性化および糖輸送活性を増強する2014

    • Author(s)
      津田諭志、江川達郎、大島里詠子、木谷一登、馬嘯、林達也
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2014-05-22 – 2014-05-24
    • Related Report
      2014 Research-status Report
  • [Presentation] ラット骨格筋におけるメトホルミンによるAMPキナーゼの急性的活性化2014

    • Author(s)
      大島里詠子、山田麻友美、黒木英梨子、荻野陽平、津田諭志、馬嘯、江川達郎、林達也
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2014-05-22 – 2014-05-24
    • Related Report
      2014 Research-status Report
  • [Book] The Plasticity of Skeletal Muscle - From Molecular Mechanism to Clinical Applications2017

    • Author(s)
      Egawa T
    • Total Pages
      292
    • Publisher
      Springer
    • Related Report
      2016 Annual Research Report
  • [Book] Phenolic Compounds2017

    • Author(s)
      Egawa T, Tsuda S, Oshima R, Goto A, Ma X, Goto K, Hayashi T
    • Total Pages
      240
    • Publisher
      InTech
    • Related Report
      2016 Annual Research Report
  • [Book] Caffeine: Consumption, Side Effects and Impact on Performance and Mood2014

    • Author(s)
      Egawa T, Tsuda S, Hamada T, Goto K, Hayashi T
    • Total Pages
      228
    • Publisher
      Nova Science Publishers
    • Related Report
      2014 Research-status Report
  • [Remarks] 研究室ホームページ

    • URL

      https://sites.google.com/site/tatsuroegawa/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 京都大学運動医科学研究室

    • URL

      http://www.hayashilab.org/

    • Related Report
      2015 Research-status Report
  • [Remarks] 豊橋創造大学生理学研究室

    • URL

      http://www.sozo.ac.jp/professor/goto_katsumasa/

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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