2014 Fiscal Year Final Research Report
Systematic understanding of genome adaptation
| Project Area | Systematic study of chromosome adaptation |
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| Project/Area Number |
22125001
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2010-04-01 – 2016-03-31
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| Keywords | 染色体適応 / 染色体 / 環境ストレス / ゲノム / 減数分裂 / 組換え |
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| Outline of Final Research Achievements |
Genome adaptation promotes the formation of new traits in next generation such as heterogeneity irrespective of homogenous genome. In this study, we revealed a new mechanism which facilitates genomic variation through chromosome structure or epi-genetic information. Moreover, we showed environmental stress such as heat shock or infection by pathogen as well as mind stress promotes a new trait in a few generation through the propagation and maintenance of specific chromosomal structures without change of DNA information. To promote more efficient analysis for data from chromatin-immunoprecipitation DNA sequence (ChIP-Seq) and genetic variation using next-generation sequencers (NGS) , we have developed a new platform for annotation of the information. To facilitate the interaction with society, we carried out classes to high school students and public in 48 cases in past 5 years.
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| Free Research Field |
分子生物学
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