2015 Fiscal Year Final Research Report
Neuronal basis of prediction and decision in the basal ganglia and amygdala.
Project Area | Elucidation of neural computation for prediction and decision making: toward better human understanding and applications |
Project/Area Number |
23120010
|
Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
|
Allocation Type | Single-year Grants |
Review Section |
Complex systems
|
Research Institution | Tamagawa University |
Principal Investigator |
KIMURA Minoru 玉川大学, 脳科学研究所, 教授 (40118451)
|
Co-Investigator(Kenkyū-buntansha) |
HARUNO Masahiko 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳情報通信融合研究室, 主任研究員 (40395124)
|
Co-Investigator(Renkei-kenkyūsha) |
SAMEJIMA Kazuyuki 玉川大学, 脳科学研究所, 教授 (30395131)
ENOMOTO Kazuki 玉川大学, 脳科学研究所, 科研費研究員 (10585904)
|
Research Collaborator |
YAMANAKA Ko 順天堂大学, スポーツ健康科学部, 助教 (40551479)
|
Project Period (FY) |
2011-04-01 – 2016-03-31
|
Keywords | 神経科学 / 生理学 / 意思決定 / 大脳基底核 / 扁桃体 |
Outline of Final Research Achievements |
We made new findings about neuronal basis of prediction and decision by conducting animal experiments and functional brain imaging of human subjects. 1.Japanese monkeys are able to make optimal decisions based on reward histories of their own as well as another monkey sitting side by side. 2.Activity of midbrain dopamine neurons and neurons in the striatum evaluate whether decision and action are rewarded or not and predict multiple future rewards through multi-step actions toward a goal. 3.Neurons in the centromedian (CM) nucleus of thalamus encode response bias to large-reward action, binding of response bias into action and unexpected change of behavioral state. 4.Activity of human amygdala and accumbens represents inequity in monetary resources delivered between oneself and another person.
|
Free Research Field |
神経生理学
|