2002 Fiscal Year Final Research Report Summary
Infection with New Type Hepatitis Viruses G and TTV, and Oral Malignant Tumors
| Project/Area Number |
12671959
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
TAKATA Yutaka Kyushu Dental College, Dentistry, Professor, 歯学部, 教授 (40163208)
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| Co-Investigator(Kenkyū-buntansha) |
KUROKAWA Hideo Kyushu Dental College, Dentistry, Associate Professor, 歯学部, 助教授 (40161781)
FUKUDA Junichi Kyushu Dental College, Dentistry, Professor, 歯学部, 教授 (00106270)
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| Project Period (FY) |
2000 – 2002
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| Keywords | Dental / Hepatitis virus / HGV / TTV / Oral cancer / Oral cyst / Oral surgery / Infection |
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| Research Abstract |
Prevalences of infection with new type hepatitis viruses G and transfusion transmitted virus (TTV) as well as with hepatitis B and C were evaluated in association with oral diseases including oral cancers. HCV antibody was more prevalent in patients with oral cancers than in those with oral cysts (8.6% vs. 4.0%), but this difference was disappeared with age adjustment. On the other hand, HBs antigen was more prevalent in patients with oral cysts than in those with oral cancers (2.1% vs. 0%), whether or not adjustment was made for age. No differences in HGV RNA or TTV DNA were found between oral cancers and oral cysts (3.2% vs. 2.8% for HGV RNA, 29.7% vs. 32.1% for TTV DNA ). There were no differences in HBs antigen, HCV antibody, HGV RNA, or TTV DNA between patients with impacted teeth and jaw deformities (1.1% vs. 0% for HBs antigen, 4.1% vs. 3.2% for HCV antibody, 1.8% vs. 0% for HGV RNA, 22.9% vs. 21.4% for TTV DNA). In conclusion, TTV DNA was much more prevalent than the other viruses. No etiological association was found between HCV infection and oral cancer.
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Research Products
(14 results)
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[Publications] Takata Y, Simoda T: "Obesity, Diabetes mellitus, Hyperlipidemia, Atherosclerosis, Cerebrovascular disease, Hypertension, Hyperuricemia, Heart disease, Renal disease"Manual of nutritional guidance, 3rd revision, Nanzando. 88-114 (2002)
Description
「研究成果報告書概要(欧文)」より
