2003 Fiscal Year Final Research Report Summary
Synthesis and Reactivity of C-and N-Bound Transitionmetal α-Cyanocarbanions
| Project/Area Number |
13450371
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
NAOTA Takeshi Osaka University, Department of Chemistry Graduate School of Engineering Science, Professor, 大学院・基礎工学研究科, 教授 (20164113)
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| Project Period (FY) |
2001 – 2003
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| Keywords | cyanocarbanion / ruthenium / Michael reaction / Aldol reaction |
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| Research Abstract |
A novel N-bound Cp ruthenium carbanion complex was synthesized to apply for the C-C bond formation reactions such as Aldol and Michael reactions. The complex can be reacted with various olefins bearing electron-withdrawing substituents to give the corresponding N-bound ruthenium complex, of which ligand was converted to Michael type adducts. Furthermore, N-bound hydrido ruthenium carbanion complex with α-alkoxycarbonyl group, as well as the complex mentioned above, was found to react with an electron deficient olefin without loss of metal-hydrido. The result suggests that catalytic Michael addition of metal-hydrido, which is generated by C-H activation of substrates, proceeds with ionic mechanism rather than hydrometalation.
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