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2002 Fiscal Year Final Research Report Summary

Intervention-studies in weight control and skeletal muscle characteristics with food restriction and exercise

Research Project

Project/Area Number 13480009
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field 体育学
Research InstitutionKYUSHU UNIVERSITY

Principal Investigator

KUMAGAI Shuzo  Institute of Health Science, Ass. Prof., 健康科学センター, 助教授 (80145193)

Co-Investigator(Kenkyū-buntansha) NAKANO Hiroshi  Department of Human Development, Nakamura Gakuen University, Assist. Prof., 人間発達学部, 講師 (60301678)
HIGAKI Yasuki  Department of Preventive Medicine, Saga Medical School, Assist. Prof., 予防医学, 講師 (10228702)
KATSURA Shigeru  Graduate School of Integrated Science and Art, University of East Asia, Prof., 大学院・総合学術研究科, 教授 (70038446)
ITO Tatsumi  Faculty of Agriculture, Prof., 大学院・農学研究院, 教授 (50038246)
Project Period (FY) 2001 – 2002
Keywordsabdominal fat / food restriction / high fat diet / leptin / obesity / oxidative enzyme / skeletal muscle characteristics / weight reduction
Research Abstract

Skeletal muscle plays an important role in energy metabolism. Therefore, its characteristics have been studied in numerous experiments on obesity as well as diabetes to investigate their contribution. According to the clinical and experimental data mainly obtained from cross-sectional studies, fiber composition, capillarization, enzyme activities in the muscle were considered to be involved in the possible pathogenesis of obesity. However, without interventions, all of these cross-sectional studies were inadequate to clarify any of these hypotheses. Longitudinal studies provided the possibility to reveal the causality between skeletal muscle characteristics and obesity. We carried out studies based on a precise study protocol. In these studies, skeletal muscle adaptation to diet-induced weight control is being investigated in rats. Visceral adipose was chosen to be the classificatory criterion. Energy intake is not significantly different. Muscle samples are collected from the same portion of the same muscle before and after the diet periods. Results which may contribute to the knowledge of obesity/lean-susceptibility are expected.

  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] Zou B.et al.: "Overview of skeletal muscle adaptation to diet-induced weight control"Jpn J Health Prom Sci. 5・1. 1-13 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Zou B.et al.: "Adaptation in skeletal muscle characteristics to a high-fat diet in rats with different intra-abdominal-obesity susceptibilities"J Nutr Sci Vitaminol. 49・4(accepted for publication). (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Zou B. et al.: "Overview of muscle adaptation to diet-induced weight control"Jpn J Health Prom Sci. 5-1. 1-13 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Zou B. et al.: "Adaptation in skeletal muscle characteristics to a high-fat diet in rats with different intra-abdominal-obesity susceptibilities"J Nutr Sci Vitaminol. accepted for publication.

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2004-04-14  

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