2004 Fiscal Year Final Research Report Summary
Formulation and Characterization of Monodispersed Microcapsules and Nanocapsules
| Project/Area Number |
14206016
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
食品科学・栄養科学
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| Research Institution | National Food Research Institute |
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Principal Investigator |
NAKAJIMA Mitsutoshi National Food Research Institute, 食品加工部, 研究部長 (10343815)
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| Project Period (FY) |
2002 – 2004
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| Keywords | Asymmetric through-hole microplate / Straight-Through Microchannel Emulsification / Monodispersed Emulsion / Channel / Slit / Water-in-oil emulsion / Silicon plate / array |
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| Research Abstract |
Research on Formulation and characterization of microcapsules and nanocapsules has been carried out, and summarized as follows.
1.Lipid micro/nanoparticles with relatively monodisperse were successfully obtained from monodispersed oil-in-water emulsion by microchannel emulsification as well as solvent evaporation method.
2.Scale up of microchannel plate was done, and microchannel emulsification capacity was increased one magnitute from former 5ml/h productivity.
3.Monodispersed gelatin-acacia microcapsules were prepared by formation of monodispersed gelatin emulsion with the use of microchannel emulsification as well as coacervate encapsulation with the use of acacia solution.
4.CFD (Computatinal Fluid Dynamics) was applied to the analysis of droplet formation from straight-through microchannel. CFD model of circular (10 μm) and oblong (10 and 40 μm) shaped though holed microchannel was constructed and the simulation results agreed well with the experimental results.
5.New device of asymmetric straight-through microchannel has been developed ; two layers of slit and micro-hole structure, and exhibited higher droplet productivity than conventional symmetric straight-through microchannel.
6.Formulation of nanoparticles was carried out by protein-based emulsion with the use of high-pressure homogenizer, and the method of encapsulation of functional component was newly developed.
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Research Products
(88 results)
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[Book] 熱帯農業事典2003
Author(s)
中嶋光敏
Total Pages
643
Publisher
養賢堂
Description
「研究成果報告書概要(和文)」より
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[Book] 農芸化学の事典2003
Author(s)
中嶋光敏
Total Pages
869(385-386)
Publisher
朝倉書店
Description
「研究成果報告書概要(和文)」より
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