2004 Fiscal Year Final Research Report Summary
Development and application of artificial acyltransferase models based on host compounds
| Project/Area Number |
14572025
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
KUNISHIMA Munetaka Kobe Gakuin University, Pharmaceutical Chemistry, Associate Professor, 薬学部, 助教授 (10214975)
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| Project Period (FY) |
2002 – 2004
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| Keywords | Host-Guest / enzyme models / amides / acyltransfer / molecular recognistion / dehydrocondensation / bioorganic chemistry |
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| Research Abstract |
Following Results are successfully obtained.
1.Development of synthetic technology utilizing for the preparation of functionalized dehydrocondensing agents available in water
2.Cyclotransferase model based on 18-crown-6
3.Development of fatty acids-specific acyl CoA transferase models in micelles.
4.Substrate-specific reactions utilizing liquid-liquid biphasic system as a reaction field
5.Novel immobilizing systems of dehydrocondensing agents, which are useful to utilize enzyme models.
6.Peptide synthesis of unprotected amino acids by use of fluorous solvents
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Research Products
(22 results)
