2017 Fiscal Year Final Research Report
Analysis of implantaion process by using Sox17 heterozygous mouse
| Project/Area Number |
15H04282
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory animal science
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KANAI Masami 東京医科歯科大学, 統合研究機構, 教授 (70321883)
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| Co-Investigator(Kenkyū-buntansha) |
平手 良和 東京医科歯科大学, 統合研究機構, 講師 (70342839)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 着床 / 不妊 / マウス / Sox17 |
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| Outline of Final Research Achievements |
Few basic and systematic research has been done for maternal implantation process of fertilized embryo which is considered to be the factor in the pregnancy failure. In this study, we have done the pathological analysis by using female Sox17 heterozygous mouse. From the result of microarray analysis using endometrial epithelium from female Sox17 heterozygous mouse, we have selected that the gene group in which the signal ratio was significantly decreased as compared with the wild type.
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| Free Research Field |
実験動物学
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