Identification of novel surface marker of cardiac progenitor cells for heart regeneration therapy

2015 Fiscal Year Final Research Report

• Project/Area Number: 15H06370
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Cardiovascular medicine
• Research Institution: Osaka University
• Principal Investigator: ISHIDA HIDEKAZU 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤) (50467552)
• Project Period (FY): 2015-08-28 – 2016-03-31
• Keywords: 心筋前駆細胞 / 次世代シーケンサー / 表面マーカー

Outline of Final Research Achievements

We identified a novel cell surface marker of cardiac progenitor cells by using next generation sequencing of single cell cDNA derived from mouse embryonic heart field. We could purify the cardiac progenitor cells from mouse embryonic stem cells as well as human embryonic / induced pluripotent stem cells. This marker can be applied for the future heart regeneration therapy, such as cardiac progenitor cell transplantation therapy.

Free Research Field

小児循環器学