2016 Fiscal Year Final Research Report
Analysis of the mechanism of interferon production in plasmacytoid dendritic cells
| Project/Area Number |
15H06454
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Experimental pathology
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| Research Institution | Kagawa University |
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Principal Investigator |
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| Project Period (FY) |
2015-08-28 – 2017-03-31
|
| Keywords | 形質細胞様樹状細胞 / インターフェロン |
|---|
| Outline of Final Research Achievements |
Plasmacytoid dendritic cells (pDC) secrete type I IFNs, which play an important role in antiviral immune responses. However, the molecular mechanisms of type I IFNs production in pDC are still not completely understood. Here we show that transcription factor HS01 regulates the production of type I IFNs in pDC.
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| Free Research Field |
免疫学
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