2016 Fiscal Year Final Research Report
Effect of Synthetic Bone Mineral to Osseointegration in a Rat Model of Osteoporosis
| Project/Area Number |
15H06645
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2015-08-28 – 2017-03-31
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| Keywords | サプリメント / 骨粗鬆症 / インプラント |
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| Outline of Final Research Achievements |
The purpose of the present study was to confirm whether intake of Synthetic bone mineral (SBM) developed for osteoporosis supplement, affect peri-implant bone formation in an ovariectomized rat.
Pull-out strength and BMD for the Diet with SBM group were significantly greater than those without SBM group.Fluorescence microscopy imaging of the Diet with SBM group demonstrated more green fluorescence (indicating bone formation) than that of the Diet without SBM group. BV/TV, BS/BV, TbTh and Vtr in the Diet with SBM group were significantly greater than those in the Diet without SBM group. This study demonstrated that SBM could be effective in accelerating peri-implant bone formation and improve the trabecular structure in an ovariectomized rat.
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| Free Research Field |
インプラント
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