2016 Fiscal Year Final Research Report
PCSK9 and coronary atherosclerosis
| Project/Area Number |
15H06914
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Cardiovascular medicine
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
Kataoka Yu 国立研究開発法人国立循環器病研究センター, 病院, 医長 (70463271)
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| Project Period (FY) |
2015-08-28 – 2017-03-31
|
| Keywords | 動脈硬化症機序解明 |
|---|
| Outline of Final Research Achievements |
We demonstrated that PCSK9 level, especially mature PCSK9 form associated with the extent of coronary atherosclerosis in patients with familial hypercholesterolemia. The association of PCSK9 with atherosclerotic cardiovascular events was also identified in the analysis of cohort study.
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| Free Research Field |
動脈硬化
|
