2016 Fiscal Year Final Research Report
Depicting neural circuit that evokes cataplexy
| Project/Area Number |
15K12768
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic / Social brain science
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| Research Institution | University of Tsukuba (2016)
Kanazawa University (2015) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | ナルコレプシー / オレキシン / 視床下部 / 睡眠障害 |
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| Outline of Final Research Achievements |
We identified several brain regions that are implicated in the emergence of cataplexy-like episodes in orexin/ataxin-3 mice, a rodent model of narcolepsy. Optogenetic excitation with specific stimulating conditions evoke cataplexy in these mice.
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| Free Research Field |
神経生理学
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