• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2016 Fiscal Year Final Research Report

Depicting neural circuit that evokes cataplexy

Research Project

  • PDF
Project/Area Number 15K12768
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Basic / Social brain science
Research InstitutionUniversity of Tsukuba (2016)
Kanazawa University (2015)

Principal Investigator

SAKURAI Takeshi  筑波大学, 医学医療系, 教授 (60251055)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywordsナルコレプシー / オレキシン / 視床下部 / 睡眠障害
Outline of Final Research Achievements

We identified several brain regions that are implicated in the emergence of cataplexy-like episodes in orexin/ataxin-3 mice, a rodent model of narcolepsy. Optogenetic excitation with specific stimulating conditions evoke cataplexy in these mice.

Free Research Field

神経生理学

URL: 

Published: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi