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2018 Fiscal Year Annual Research Report

先端モデル動物支援プラットフォーム

Research Project

Project/Area Number 16H06276
Research InstitutionThe University of Tokyo

Principal Investigator

今井 浩三  東京大学, 医科学研究所, 客員教授 (60117603)

Co-Investigator(Kenkyū-buntansha) 中村 卓郎  公益財団法人がん研究会, がん研究所, 副所長 (00180373)
井上 純一郎  東京大学, 医科学研究所, 教授 (70176428)
高田 昌彦  京都大学, 霊長類研究所, 教授 (00236233)
山田 泰広  東京大学, 医科学研究所, 教授 (70313872)
高橋 智  筑波大学, 医学医療系, 教授 (50271896)
伊川 正人  大阪大学, 微生物病研究所, 教授 (20304066)
﨑村 建司  新潟大学, 脳研究所, フェロー (40162325)
荒木 喜美  熊本大学, 生命資源研究・支援センター, 教授 (90211705)
八尾 良司  公益財団法人がん研究会, がん研究所・細胞生物部, 部長 (80291095)
真下 知士  大阪大学, 大学院医学系研究科, 准教授 (80397554)
小林 和人  福島県立医科大学, 医学部, 教授 (90211903)
豊國 伸哉  名古屋大学, 大学院医学系研究科, 教授 (90252460)
鰐渕 英機  大阪市立大学, 大学院医学研究科, 教授 (90220970)
今井田 克己  香川大学, 医学部, 教授 (90160043)
二口 充  長崎大学, 病院(医学系), 准教授 (60275120)
上野 正樹  香川大学, 医学部, 教授 (30322267)
宮崎 龍彦  岐阜大学, 医学部附属病院, 准教授 (80239384)
神田 浩明  埼玉県立がんセンター(臨床腫瘍研究所), 病理診断科, 部長 (90260067)
尾藤 晴彦  東京大学, 大学院医学系研究科, 教授 (00291964)
宮川 剛  藤田保健衛生大学, 総合医科学研究所, 教授 (10301780)
高雄 啓三  富山大学, 研究推進機構・研究推進総合支援センター, 教授 (80420397)
池田 和隆  公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 分野長 (60281656)
虫明 元  東北大学, 大学院医学系研究科, 教授 (80219849)
清宮 啓之  公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 (50280623)
長田 裕之  国立研究開発法人理化学研究所, 環境資源科学研究センター, 副センター長 (80160836)
旦 慎吾  公益財団法人がん研究会, がん化学療法センター・分子薬理部, 部長 (70332202)
井本 正哉  慶應義塾大学, 理工学部, 教授 (60213253)
川田 学  公益財団法人微生物化学研究会, 微生物化学研究所・第1生物活性研究部, 部長 (20300808)
田原 栄俊  広島大学, 大学院医歯薬保健学研究科(薬), 教授 (00271065)
吉田 稔  国立研究開発法人理化学研究所, 環境資源科学研究センター, グループディレクター (80191617)
松浦 正明  帝京大学, 大学院公衆衛生学研究科, 教授 (40173794)
牛嶋 大  公益財団法人がん研究会, 有明病院・臨床研究・開発センター, 研究員 (60328565)
Project Period (FY) 2016 – 2021
Keywordsモデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング
Outline of Annual Research Achievements

①総括支援活動 : ホームページ(HP)に改良を加えながら公募の円滑化をさらに進めた。モデル動物作製解析の講習や若手研究者の交流促進を推進する技術講習会を開催した。また成果発表会を開催、全国から127名の参加があり一般口演ならびにポスター発表など、本活動の支援成果を、より幅広い研究分野にアピールした。
②モデル動物作製支援活動 : 利用者の様々な要望に個別に対応し、相同組換えやゲノム編集など先進的な遺伝子改変技術を用いて、遺伝子改変マウスおよびラットを合計83件、迅速に作製し、学術研究を推進するための研究リソースを提供した。
③病理形態解析支援活動 : 昨年より多い52件の申請を受け、2回の審査の結果、42件に関して病理形態解析を実施した。研究の方向性を裏付ける多くの成果が得られた。論文の図の作成にもかかわり、論文が受理されるまで支援を実施した。
④生理機能解析支援活動 : 行動学的解析では23課題、薬理学的解析では9課題、光技術による操作解析では10課題、多機能電極・計測データ解析では16課題をそれぞれ支援し、動物モデルにおける病態・生理学的基盤の解明推進に関する支援を展開した。
⑤分子プロファイリング支援活動 : 依頼化合物の分子プロファイリング308件、阻害剤キット配付102枚、RNA干渉キット配付・siRNAデザイン合成92件、バーコードshRNAライブラリーによる化合物の標的経路探索24件、を実施した。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

①総括支援活動 : 公募申請と選考作業の効率化が促進された。技術講習会と成果発表会で多くの参加者を得た。参加者対象のアンケートから若手の研究意欲を促進する効果が明らかとなった。参加希望者が前年度よりも増え、参加者の研究分野の多様性が一層顕著になった。
②モデル動物作製支援活動 : 研究実施計画に沿った支援を行うことができている。増加傾向にある応募課題に対し、最新技術を導入することにより効率化を図り、予算が許す範囲で可能な課題数を採択し、支援を行なった。遺伝子改変が複雑あるいは技術的に難しいケースは、必要な技術を導入・開発することにより対応している。
③病理形態解析支援活動 : 年々申請数が増加しており、審査をより厳格に行っている。現在の予算ならびに班員のエフォートにおいてできる最大限の支援活動を実施しており、成果は確実に上がっている。
④生理機能解析支援活動 : 支援対象者のモデルマウスを対象にした感覚・運動・認知機能に関わる「網羅的行動テストバッテリー」を用いた行動解析支援を23課題、依存性薬物等の感受性に関連する行動解析および臨床データと遺伝子多型との関連解析を行う規制薬物作用解析支援を9課題、進展著しい光遺伝学に関する最新技術を活用した研究支援を10課題、多機能集積化電極による最先端の技術提供を行う多元的生理機能計測操作支援を16課題で実施した。
⑤分子プロファイリング支援活動 : 応募課題の審査体制が軌道に乗り、採否決定までの所要日数が前年度と比較して最大10日程度短縮された。応募前の技術相談を積極的に受け付けたことで、幅広い分野から新規ユーザーを獲得することができた。前年度までの支援成果を受けて高次評価に進んだ課題については、複数の支援担当者間での連携が功を奏した。shRNAライブラリー探索支援では実験条件をカスタマイズし、被支援者の特殊なニーズにも応えた。

Strategy for Future Research Activity

①総括支援活動 : 支援により得られた成果の広報にも力を入れるとともに、被支援者にも本支援活動の重要性をアピールしてもらうよう働きかける。技術講習会では4プラットフォームとの連携を推進し、H31年度は先進ゲノム解析研究支援プラットフォームから講師と参加者を受け入れる。
②モデル動物作製支援活動 : 先端的なゲノム編集技術や研究リソース等を用いて、支援活動の拡充を図るとともに、革新的な遺伝子改変技術および周辺技術の導入・開発を進めることにより、学術研究の推進に貢献するとともに、学術基盤としての研究リソースを整備する。
③病理形態解析支援活動 : 現状で予算ならびに支援を担当する班員の対応状況に関して厳しい状態となっていることから、今後は審査をより厳格に行い、成果につながる可能性が高い申請を選択する。基本姿勢として、一旦開始した病理形態支援は論文が受理されるまでサポートするという方針に変化はない。
④生理機能解析支援活動 : 5つの拠点への支援申請が何れも安定して多数あることから、引き続きニーズに応えられるように拠点における技術力を維持・向上させ、支援実施体制をハイレベルに保つ。また、研究者コミュニティーにおける支援事業の認知度を向上させるため、学会等での広報活動を行う。技術支援にとどまらず、支援該当部の論文分担執筆を積極的に進め、成果の公表にも貢献する。
⑤分子プロファイリング支援活動 : H30年度に引き続き、広報活動の強化・解析条件のカスタマイズ対応・支援実施後のフォロー(科学的助言、共同究の斡旋、高次支援の勧奨)に努めるとともに、年2回の定例班会議で問題点を洗い出し、常に最善の運用体制で支援を実施する。支援内容の性質上、個体レベルの研究を行わない研究者層が主要な被支援者層と一致しているが、共同研究や他の支援活動班との連絡を通じて、個体レベルの研究にも展開させたい。

  • Research Products

    (874 results)

All 2019 2018 Other

All Int'l Joint Research (6 results) Journal Article (281 results) (of which Int'l Joint Research: 57 results,  Peer Reviewed: 277 results,  Open Access: 152 results) Presentation (502 results) (of which Int'l Joint Research: 128 results,  Invited: 144 results) Book (12 results) Remarks (62 results) Patent(Industrial Property Rights) (11 results) (of which Overseas: 3 results)

  • [Int'l Joint Research] コロンピア大学/イリノイ大学/タフツ大学(米国)

    • Country Name
      U.S.A.
    • Counterpart Institution
      コロンピア大学/イリノイ大学/タフツ大学
    • # of Other Institutions
      8
  • [Int'l Joint Research] ボルドー大学/マリーキューリー医科大学/グルノーブルアルプス大学(フランス)

    • Country Name
      FRANCE
    • Counterpart Institution
      ボルドー大学/マリーキューリー医科大学/グルノーブルアルプス大学
    • # of Other Institutions
      1
  • [Int'l Joint Research] 江蘇大学/Xi'an Jiaotong University(中国)

    • Country Name
      CHINA
    • Counterpart Institution
      江蘇大学/Xi'an Jiaotong University
  • [Int'l Joint Research] Seoul national University/韓南大学(韓国)

    • Country Name
      KOREA (REP. OF KOREA)
    • Counterpart Institution
      Seoul national University/韓南大学
  • [Int'l Joint Research] シンガポール国立大学(シンガポール)

    • Country Name
      SINGAPORE
    • Counterpart Institution
      シンガポール国立大学
  • [Int'l Joint Research]

    • # of Other Countries
      4
  • [Journal Article] A Polymorphic Variant in p19Arf Confers Resistance to Chemically Induced Skin Tumors by Activating the p53 Pathway2019

    • Author(s)
      Saito M, Okumura K, Isogai E, Araki K, Tanikawa C, Matsuda K, Kamijo T, Kominami R, Wakabayashi Y.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 139 Issue: 7 Pages: 1459-1469

    • DOI

      10.1016/j.jid.2018.12.027

    • Peer Reviewed / Open Access
  • [Journal Article] Concurrent expression of CD47 and CD44 in colorectal cancer promotes malignancy2019

    • Author(s)
      Fujiwara-Tani R, Sasaki T, Ohmori H, Luo Y, Goto K, Nishiguchi Y, Mori S, Nakashima C, Mori T, Miyagawa Y, Kawahara I, Fujii K, Kishi S, Tatsumoto N, Kuniyasu H
    • Journal Title

      Pathobiology

      Volume: 86 Pages: 182-189

    • DOI

      10.1159/000496027

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Iron Addiction with Ferroptosis-resistance in Asbestos-induced Mesothelial Carcinogenesis : Toward the Era of Mesothelioma Prevention.2019

    • Author(s)
      Toyokuni S
    • Journal Title

      Free Radic Biol Med

      Volume: 133 Pages: 206-215

    • DOI

      10.1016/j.freeradbiomed.2018.10.401

    • Peer Reviewed
  • [Journal Article] Targeting claudin-4 enhances CDDP-chemosensitivity of gastric cancer2019

    • Author(s)
      Nishiguchi Y, Fujiwara-Tani R, Sasaki T, Luo Y, Ohmori H, Kishi S, Mori S, Goto K, Yasui W, Sho M*, Kuniyasu H
    • Journal Title

      Oncotarget

      Volume: 10 Pages: 2189-2202

    • DOI

      10.18632/oncotarget.26758

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Functional emergence of a column-like architecture in layer 5 of mouse somatosensory cortex in vivo.2019

    • Author(s)
      Koizumi K, Inoue M, Chowdhury S, Bito H, Yamanaka A, Ishizuka T, Yawo H.
    • Journal Title

      J Physiol Sci.

      Volume: 69 Issue: 1 Pages: 65-77

    • DOI

      10.1007/s12576-018-0618-4

    • Peer Reviewed
  • [Journal Article] Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model2019

    • Author(s)
      Htun Y, Nakamura S, Nakao Y, Mitsuie T, Nakamura M, Yamato S, Jinnai W, Koyano K, Ohta K, Morimoto A, Wakabayashi T, Sugino M, Fujioka K, Kato I, Kondo S, Yasuda S, Miki T, Ueno M, Kusaka T
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 4088

    • DOI

      10.1038/s41598-019-40674-8

    • Peer Reviewed / Open Access
  • [Journal Article] Optogenetic study of the response interaction among multi-afferent inputs in the barrel cortex of rats.2019

    • Author(s)
      Liu Y, Ohshiro T, Sakuragi S, Koizumi K, Mushiake H, Ishizuka T, Yawo H.
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 3917

    • DOI

      10.1038/s41598-019-40688-2

    • Peer Reviewed / Open Access
  • [Journal Article] Scn2a haploinsufficient mice display a spectrum of phenotypes affecting anxiety, sociability, memory flexibility and ampakine CX516 rescues their hyperactivity2019

    • Author(s)
      Tatsukawa T, Raveau M, Ogiwara I, Hattori S, Miyamoto H, Mazaki E, Itohara S, Miyakawa T, Montal M, Yamakawa K*
    • Journal Title

      Mol Autism

      Volume: 10 Pages: 15

    • DOI

      10.1186/s13229-019-0265-5.eCollection2019

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-l, a simplified analog of debromoaplysiatoxin2019

    • Author(s)
      Ashida, Y., Yanagita, R. C., Kawanami, Y., Okamura, M., Dan, S. and Irie, K.
    • Journal Title

      Heterocycles

    • DOI

      10.3987/COM-18-S(F)60

    • Peer Reviewed
  • [Journal Article] Analysis of Neuro-Neuronal Synapses Using Embryonic Chick Ciliary Ganglion via Single-Axon Tracing, Electrophysiology, and Optogenetic Techniques.2019

    • Author(s)
      Egawa R. Yawo H.
    • Journal Title

      Curr Protoc Neurosci.

      Pages: e64

    • DOI

      10.1002/cpns.64

    • Peer Reviewed
  • [Journal Article] Structures and biological activities of new carnosic acid- and carnosolrelated compounds generated by heat treatment of rosemary2019

    • Author(s)
      Yu Buchin, Yuka Sakemi, Ruriko Hamashima, Yuko Morioka, Daisuke Yamanaka, Fumihiko Hakuno, Shin-ichiro Takahashi, Kazutoshi Shindo
    • Journal Title

      Phytochemistry Letters

      Volume: 30 Pages: 43-48

    • DOI

      10.1016/j.phytol.2019.01.005

    • Peer Reviewed
  • [Journal Article] Lineage-specific RUNX2 super-enhancer activates MYC via a chromosomal translocation and promotes the development of blastic plasmacytoid dendritic cell neoplasm2019

    • Author(s)
      Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Oshima M, Tan KT, Yang H, Kanai A. Iwanaga E, Asou N, Maeda T, Nakagata N. Ito T, Iwama A. Ohyashiki K, Osato M, Sashida G.
    • Journal Title

      Nat Commun

      Volume: 10 Issue: 1 Pages: 1653

    • DOI

      10.1038/s41467-019-09710-z

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ipsilateral-dominant control of limb movements in rodent posterior parietal cortex.2019

    • Author(s)
      *Soma S, Yoshida J, Kato S, Takahashi Y, Nonomura S, Sugimura YK, Rfos A, Kawabata M, Kobayashi K, Kato F, Sakai Y, Isomura Y
    • Journal Title

      The Journal of Neuroscience

      Volume: 39 Issue: 3 Pages: 485-502

    • DOI

      10.1523/JNEUROSCI.1584-18.2018

    • Peer Reviewed
  • [Journal Article] TFE3 Xpll. 2 translocation renal cell carcinoma mouse model reveals novel therapeutic targets and identifies GPNMB as a diagnostic marker for human disease2019

    • Author(s)
      Masaya Baba, Mitsuko Furuya, Takanobu Motoshima, Martin Lang, Shintaro Funasaki, Wenjuan Ma, Hong-Wei Sun, Hisashi Hasumi, Ying Huang, Ikuma Kato, Tsuyoshi Kadomatsu, Yorifumi Satou, Nicole Morris, Baktiar O, Karim, Lilia Ileva, Joseph D. Kalen, Luh Ade Wilan Krisna, Kimi Araki, et al.
    • Journal Title

      Molecular Cancer Research

    • DOI

      10.1158/1541-7786

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Stereo-Divergent Synthesis of Bispyrrolidinoindoline Alkaloidal Scaffolds and Generation of a Lead Candidate with Stereospecific Anti-proliferative Activity2019

    • Author(s)
      Mitsuhiro Wada, Hiroyuki Suzuki, Mitsuyasu Kato, Hideaki Oikawa, Akira Tsubouchi, Hiroki Oguri
    • Journal Title

      ChemBioChem

    • DOI

      10.1002/cbic.201800815

    • Peer Reviewed
  • [Journal Article] Forkhead box protein Al confers resistance to transforming growth factor-β-induced apoptosis in breast cancer cells through inhibition of Smad3 nuclear translocation.2019

    • Author(s)
      Hirata K, Takakura Y, Shibazaki M, Morii M, Honda T, Oshima M, Aoyama K, Iwama A, Nakayama Y, Takano H, Yamaguchi N, Yamaguchi N
    • Journal Title

      J Cell Biochem.

      Volume: 120 Pages: 2259-2270

    • DOI

      10.1002/jcb.27551

    • Peer Reviewed
  • [Journal Article] Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo [g] [1] benzopyrano [4, 3-b] indol-6 (13H)-one scaffold2019

    • Author(s)
      Tsutomu Fukuda, Yusuke Nanjo, Masahiro Fujimoto, Kenyu Yoshida, Yuko Natsui, Fumito Ishibashi, Fumiyasu Okazaki, Hideto To, Masatomo Iwao
    • Journal Title

      Bioorganic and Medicinal Chemistry

      Volume: 27 Issue: 2 Pages: 265-277

    • DOI

      10.1016/j.bmc.2018.11.037

    • Peer Reviewed / Open Access
  • [Journal Article] Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.2019

    • Author(s)
      Okada, K., Araki, M., Sakashita, T., Ma, B., Kanda, R., Yanagitani, N., Horiike, A., Koike, S., Oh-Hara, T., Watanabe, K., Tamai, K., Maemondo, M., Nishio, M., Ishikawa, T., Okuno, Y., Fujita, N. and *Katayama, R.
    • Journal Title

      EBioMedicine

    • DOI

      10.1016/j.ebiom.2019.01.019

    • Peer Reviewed / Open Access
  • [Journal Article] High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme.2019

    • Author(s)
      Kamil M, Shinsato Y, Higa N, Hirano T, Idogawa M, Takajo T, Minami K, Shimokawa M, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K.
    • Journal Title

      British Journal of Cancer

    • DOI

      10.1038/s41416-019-0413-x

    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis and evaluation of topoisomerase I inhibitors possessing the 5, 13-dihydro-6H-benzo [6, 7] indolo [3, 2-c] quinolin-6-one scaffold2019

    • Author(s)
      Tsutomu Fukuda, Yuri Matsuo, Fuyuki Matsuoka, Naoki Yoshioka, Gen Onodera, Masanari Kimura, Fumito Ishibashi, Masatomo Iwao
    • Journal Title

      Heterocycles

      Volume: 99

    • DOI

      10.3987/COM-18-S(F)70

    • Peer Reviewed / Open Access
  • [Journal Article] mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.2019

    • Author(s)
      Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H.
    • Journal Title

      Pharmacol Biochem Behav.

      Volume: 176 Pages: 1-5

    • DOI

      10.1016/j.pbb.2018.11.003

    • Peer Reviewed / Open Access
  • [Journal Article] Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluAl C-terminal palmitoylation deficient mice.2019

    • Author(s)
      Itoh M, Okuno H, Yamada D, Yamashita M, Abe M, Natsume R, Kaizuka T, Sakimura K, Hoshino M, Mishina M, Wada K, Sekiguchi M, Hayashi T
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 39 Pages: 61-66

    • DOI

      10.1002/npr2.12044

    • Peer Reviewed / Open Access
  • [Journal Article] Measuring Nonselective and Selective Autophagy in the Liver2019

    • Author(s)
      Ueno T, Kaomatsu M
    • Journal Title

      Methods Mol Biol.

      Volume: 1880

    • DOI

      10.1007/978-1-4939-8873-0_34

    • Peer Reviewed
  • [Journal Article] Reconsolidation/Destabilization, Extinction and Forgetting of Fear Memory as Therapeutic Targets for PTSD.2019

    • Author(s)
      Kida, S
    • Journal Title

      Psychopharmacology

      Volume: 236 Pages: 49-57

    • DOI

      10.1007/s00213-018-5086-2

    • Peer Reviewed / Open Access
  • [Journal Article] NSP-C contributes to the upregulation of CLOCK/BMALl-mediated transcription.2019

    • Author(s)
      Hosoda, H., *Kida, S
    • Journal Title

      Cytotechnology

      Volume: 71 Pages: 453-460

    • DOI

      10.1007/s10616-018-0266-9

    • Peer Reviewed
  • [Journal Article] CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi.2019

    • Author(s)
      Ohta K, Aoyama E, Ahmad SAI, Ito N, Anam MB, Kubota S, Takigawa M.
    • Journal Title

      J Cell Commun Signal.

      Volume: 13 Issue: 1 Pages: 113-118

    • DOI

      10.1007/s12079-018-0487-x

    • Peer Reviewed
  • [Journal Article] Deregulated Polycomb functions in myeloproliferative neoplasms.2019

    • Author(s)
      Sashida G, Oshima M, Iwama A.
    • Journal Title

      Int J Hematol

    • DOI

      10.1007/s12185-019-02600-6

    • Peer Reviewed
  • [Journal Article] Chondroitin sulfate N-acetylgalactosaminyltransferase-2 deletion alleviates lipoprotein retention in early atherosclerosis and attenuates aortic smooth muscle cell migration.2019

    • Author(s)
      Adhikara IM, *Yagi K, Mayasari DS, Ikeda K, Kitagawa H, Miyata O, Igarashi M, Hatakeyama K, Asada Y, Hirata K, Emoto N
    • Journal Title

      Biochem Biophys res Commun

      Volume: 509 Pages: 89-95

    • DOI

      10.1016/j.bbrc.2018.12.068

    • Peer Reviewed
  • [Journal Article] Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-кBsignaling2019

    • Author(s)
      Katsuya K, Oikawa D, Iio K, Obika S, Hori Y, Urashima T, Ayukawa K, Tokunaga F.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 509 Issue: 3 Pages: 700-706

    • DOI

      10.1016/j.bbrc.2018.12.164

    • Peer Reviewed
  • [Journal Article] Role for tyrosine phosphorylation of SUV39H1 histone methyltransferase in enhanced trimethylation of histone H3K9 via neuregulin-1/ErbB4 nuclear signaling.2019

    • Author(s)
      Nakajo H, Ishibashi K, Aoyama K, Kubota S, Hasegawa H, Yamaguchi N, Yamaguchi N
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 511 Pages: 765-771

    • DOI

      10.1016/j.bbrc.2019.02.130

    • Peer Reviewed
  • [Journal Article] Model studies for isolation of G-quadruplex-forming DNA sequences through a pull-down strategy with macrocyclic polyoxazole2019

    • Author(s)
      Keisuke Iida, Yamato Tsushima, Yue Ma, Shadi Sedghi Masoud, Mai Sakuma, Tomomi Yokoyama, Wataru Yoshida, Kazunari Ikebukuro, Kazuo Nagasawa
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 27 Issue: 8 Pages: 1742-1746

    • DOI

      10.1016/j.bmc.2019.02.056

    • Peer Reviewed
  • [Journal Article] Analysis of the neuronal network of the medullary respiratory center in transgenic rats expressing archaerhodopsin-3 in Phox2b-expressing cells.2019

    • Author(s)
      Ikeda K, Kaneko R Yanagawa Y, Ogawa M, et al.
    • Journal Title

      Brain Res Bull

      Volume: 144 Pages: 39-45

    • DOI

      10.1016/j.brainresbull.2018.11.005

    • Peer Reviewed
  • [Journal Article] Dietary magnesium deficiency impairs hippocampus-dependent memories without changes in the spine density and morphology of hippocampal neurons in mice.2019

    • Author(s)
      Serita, T., Miyahara, M., Tanimizu, T., Takahashi, S., Oishi, S., Nagayoshi, T., Tsuji, R., Inoue, H., Uehara, M., Kida, S*.
    • Journal Title

      Brain Res Bull.

      Volume: 144 Pages: 149-157

    • DOI

      10.1016/j.brainresbull.2018.11.019

    • Peer Reviewed / Open Access
  • [Journal Article] Comparative evaluation of genetically encoded voltage indicators2019

    • Author(s)
      Bando Y*, Sakamoto M* (Co-first and corresponding author), Kim S, Ayzenshtat I, Yuste R.
    • Journal Title

      Cell Reports

      Volume: 26 Issue: 3 Pages: 802-813

    • DOI

      10.1016/j.celrep.2018.12.088

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Large Timescale Interrogation of Neuronal Function by Fiberless Optogenetics Using Lanthanide Micro-particles. 26(4) : 1033-1043. e5.2019

    • Author(s)
      Miyazaki T, Chowdhury S, Yamashita T, Matsubara T, Yawo H, Yuasa H, Yamanaka A.
    • Journal Title

      Cell Rep.

      Volume: 26 Issue: 4 Pages: 1033-1043.e5.

    • DOI

      10.1016/j.celrep.2019.01.001

    • Peer Reviewed / Open Access
  • [Journal Article] Ras activation in retinal progenitor cells induces tumor formation in the eye2019

    • Author(s)
      Koso H, Tsuhako A, Matsubara D, Fujita Y, Watanabe S.
    • Journal Title

      Exp, Eye Res.

      Volume: 180 Pages: 39-42

    • DOI

      10.1016/j.exer.2018.11.025

    • Peer Reviewed
  • [Journal Article] Defecation initiates walking in the cricket Gryllus bimaculatus2019

    • Author(s)
      Naniwa K., Sugimoto Y., Osuka K. and Aonuma H.
    • Journal Title

      J. Insect Physiol.

      Volume: 112 Pages: 117-122

    • DOI

      10.1016/j.jinsphys.2018.11.004

    • Peer Reviewed
  • [Journal Article] The translation inhibitor Rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA.2019

    • Author(s)
      Iwasaki S. *, Iwasaki W., Takahashi M., Sakamoto A., Watanabe C., Shichino Y., Floor SN., Fujiwara K., Mito M., Dodo K., Sodeoka M., Imataka H., Honma T., Fukuzawa K., Ito T. *, and Ingolia NT. *
    • Journal Title

      Mol. Cell

      Volume: 73 Pages: 1-10

    • DOI

      10.1016/j.molcel.2018.11.026

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP.2019

    • Author(s)
      Kurosaki H. Yamaguchi K, Man-Yoshi K, Muramatsu SI, Hara S, Ichinose H
    • Journal Title

      Neurochemistry International

      Volume: 125 Pages: 16-24

    • DOI

      10.1016/j.neuint.2019.02.005

    • Peer Reviewed
  • [Journal Article] Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning.2019

    • Author(s)
      Macpherson T, Mizoguchi H, Yamanaka A, Hikida T.
    • Journal Title

      Neurochem Int

      Volume: 126 Pages: 11-18

    • DOI

      10.1016/j.neuint.2019.02.011

    • Peer Reviewed
  • [Journal Article] Carboxymethylation of CRMP2 is associated with decreased Schwann cell myelination efficiency.2019

    • Author(s)
      Saitoh F, Hagiwara H, Wakatsuki S, Araki T.
    • Journal Title

      Neuroscience Resarch

      Volume: 139 Pages: 58-62

    • DOI

      10.1016/j.neures.2018.08.015

    • Peer Reviewed
  • [Journal Article] Inhibition of collapsin response mediator protein-2 phosphorylation ameliorates motor phenotype of ALS model mice expressing SODIG93A.2019

    • Author(s)
      Numata-Uematsu Y, Wakatsuki S, Nagano S, Shibata M, Sakai K, Ichinohe N, Mikoshiba K, Ohshima T, Yamashita N, Goshima Y, Araki T.
    • Journal Title

      Neuroscience Resarch

      Volume: 139 Pages: 63-68

    • DOI

      10.1016/j.neures.2018.08.016

    • Peer Reviewed
  • [Journal Article] Different types of suppression-burst patterns in patients with epilepsy of infancy with migrating focal seizures (EIMFS).2019

    • Author(s)
      Yoshitomi S, Takahashi Y, Imai K, Koshimizu E, Miyatake S, Nakashima M, Saitsu H, Matsumoto N, Kato M, Fujita T, Ishii A, Hirose S, Inoue Y.
    • Journal Title

      Seizure

      Volume: 65 Pages: 118-123

    • DOI

      10.1016/j.seizure.2019.01.009

    • Peer Reviewed
  • [Journal Article] Desuppression of TGF-β signaling via nuclear c-Abl-mediated phosphorylation of TIF1γ/TRJM33 at Tyr-524. -610, and -1048.2019

    • Author(s)
      Yuki R, Tatewaki T, Yamaguchi N, Aoyama K, Honda T, Kubota S, Morii M, Manabe I, Kuga T, Tomonaga T, Yamaguchi N
    • Journal Title

      Oncogene

      Volume: 38 Pages: 635-655

    • DOI

      10.1038/s41388-018-0481-z

    • Peer Reviewed
  • [Journal Article] Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-β and NLRP3 inflammasome signaling pathway.2019

    • Author(s)
      Nam SA, Kim WY, Kim JW, Park SH, Kim Hl, Lee MS, Komatsu M, Ha H, Lim JH, Park CW, Yang CW, Kim J, Kim YK.
    • Journal Title

      Cell Death Dis.

      Volume: 10 Issue: 2 Pages: 535-540

    • DOI

      10.1038/s41419-019-1356-0

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Autophagy regulates lipid metabolism through selective turnover of NCoRl2019

    • Author(s)
      Saito T., Komatsu M. (19人中19番目)
    • Journal Title

      Nat. Commun.

      Volume: 10 Issue: 1 Pages: 1567

    • DOI

      10.1038/s41467-019-08829-3

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cdkl-mediated DIAPHI phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase.2019

    • Author(s)
      Nishimura K, Johmura Y, Deguchi K, Jiang Z, Uchida KSK, Suzuki N, Shimada M, Chiba Y, Hirota T, Yoshimura SH, Kono K, Nakanishi M.
    • Journal Title

      Nautre communications

      Volume: 10 Issue: 1 Pages: 981

    • DOI

      10.1038/s41467-019-08957-w

    • Peer Reviewed / Open Access
  • [Journal Article] Upconversion Amplification through Dielectric Superlensing Modulation.2019

    • Author(s)
      Liang L, Teb D, Dinh ND, Chen W, Chen Q, Wu Y, Chowdhury S, Yamanaka A, Sum TC, Chen CH, Thakor N, All A, Liu X
    • Journal Title

      Nat Commun

      Volume: 10 Issue: 1 Pages: 1391

    • DOI

      10.1038/s41467-019-09345-0

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reversible S-glutathionylation of human 6-pyruvoyl tetrahydropterin synthase protects its enzymatic activity.2019

    • Author(s)
      Hara S, Fukumura S, Ichinose H
    • Journal Title

      J Biol Chem

      Volume: 294 Pages: 1420-1427

    • DOI

      10.1074/jbc.RA118.005280

    • Peer Reviewed
  • [Journal Article] Markerless visual servo control of a servosphere for behavior observation of a variety of wandering animals2019

    • Author(s)
      Iwatani Y, Ogawa, H, Shidara H, Sakura M, Sato T. Hojo MK, Honma A, Tsurui K
    • Journal Title

      Advanced Robotics

      Volume: 33 Pages: 183-194

    • DOI

      10.1080/01691864.2019.1570334

    • Peer Reviewed
  • [Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer.2019

    • Author(s)
      Gong B., Kiyotani K., Sakata S., Nagano S., Kumehara S., Baba S., Besse B., Yanagitani N., Friboulet L., Nishio M., Takeuchi K., Kawamoto H., Fujita N., *Katayama R.
    • Journal Title

      J Exp Med.

    • DOI

      10.1084/jem.20180870

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.2019

    • Author(s)
      Muto Y., Moroishi T., Ichihara K., Nishiyama M., Shimizu H., Eguchi H., Moriya K., Koike K., Mimori K., Mori M., Katayama Y., Nakayama KI.
    • Journal Title

      J. Exp. Med.

      Volume: 216 Issue: 4 Pages: 950-965

    • DOI

      10.1084/jem.20180900

    • Peer Reviewed / Open Access
  • [Journal Article] Prefrontal-Enriched SLITI Expression in Primate Cortex and its Alteration during Cortical Development2019

    • Author(s)
      Tetsuya Sasaki (Corresponding Author), Yusuke Komatsu, Tetsuo Yamamori (Corresponding Author)
    • Journal Title

      Japanese Journal of Biological Psychiatry

      Volume: 20 Issue: 10 Pages: 2496-2510

    • DOI

      10.1093/cercor/bhp319

    • Peer Reviewed
  • [Journal Article] NPY deficiency prevents postmenopausal adiposity by augmenting estradiol-mediated browning.2019

    • Author(s)
      Park S, Nayantai E, Komatsu T, Hayashi H, Mori R, Shimokawa Ⅰ
    • Journal Title

      J Gerontol A Biol Sci Med Sci.

    • DOI

      10.1093/gerona/gly282

    • Peer Reviewed / Open Access
  • [Journal Article] Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs.2019

    • Author(s)
      Furusho, K., T. Shibata, R. Sato, R. Fukui, Y, Motoi, Y, Zhang, S. I. Saitoh, T. Ichinohe, M. Moriyama, S. Nakamura, and K. Miyake.
    • Journal Title

      Int Immunol.

      Volume: 31 Pages: 167-173

    • DOI

      10.1093/intimm/dxy075

    • Peer Reviewed / Open Access
  • [Journal Article] ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus.2019

    • Author(s)
      Saitoh, S. I., Y. M. Saitoh, K. Kontani, K. Sato, and K. Miyake.
    • Journal Title

      Int Immunol.

      Volume: 31 Issue: 4 Pages: 225-237

    • DOI

      10.1093/intimm/dxy084

    • Peer Reviewed / Open Access
  • [Journal Article] Cholera toxin B induces interleukine-1β production from resident peritoneal macrophages through pyrin as well as NLRP3 inflammasome.2019

    • Author(s)
      Orimo, T., I. Sasaki, H. Hemmi, T. Ozasa, Y. Fukuda-Ohta, T. Ohta, M. Morinaka, M. Kitauchi, T. Yamaguchi, Y. Sato, T. Tanaka, K. Hoshino, K. I. Katayama, S. Fukuda, K. Miyake, M. Yamamoto, T. Satoh, K. Furukawa, E. Kuroda, K. J. Ishii, K. Takeda, and T. Kaisho.
    • Journal Title

      Int Immunol.

    • DOI

      10.1093/intimm/dxz004

    • Peer Reviewed / Open Access
  • [Journal Article] Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice.2019

    • Author(s)
      Zhang T, Yanagida J, Kamii H, Wada S, Domoto M, Sasase H, Deyama S, Takarada T, Hinoi E, Sakimura K, Yamanaka A, Maejima T, Mieda M, Sakurai T, Nishitani N, Nagayasu K, Kaneko S, Minami M, Kaneda K.
    • Journal Title

      Addict Biol

    • DOI

      10.1111/adb.12723

    • Peer Reviewed
  • [Journal Article] TUBB1 dysfunction identified in familial platelet disorder causes impaired proplatelet formation and genome instability2019

    • Author(s)
      Matsumura T, Nakamura-Ishizu A, Maki H, Takaoka K, Muddineni SSNA, Wang CQ, Suzushima H, Kawakita M, Asou N, Matsuoka M, Kurokawa M, Osato M, Suda T
    • Journal Title

      Br J Haematol

    • DOI

      10.1111/bjh.15835

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] SCF(Fbxw7) ubiquilylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation.2019

    • Author(s)
      Sugiyama S., Yumimoto K., Inoue I., Nakayama KI.
    • Journal Title

      Genes Cells

    • DOI

      10.1111/gtc.12680

    • Peer Reviewed / Open Access
  • [Journal Article] RBM10-TFE3 Renal Cell Carcinoma Characterized by Paracentric Inversion with Consistent Closely Split Signals in Break-apart Fluorescence in situ Hybridization : Study of Ten Cases and a Literature Review2019

    • Author(s)
      Ikuma Kato, Mitsuko Furuya, Masaya Baba, Yoichi Kameda, Masanori Yasuda, Koshiro Nishimoto, Masafumi Oyama, Toshinari Yamasaki, Osamu Ogawa, Hitoshi Niino, Noboru Nakaigawa, Yuta Yano, Kazumasa Sakamoto, Yoji Urata, Kazuya Mikami, Shigetaka Yamasaki, Reiko Tanaka, Toshio Takagi, Tsunenori Kondo, Yoji Nagashima
    • Journal Title

      Histopathology

    • DOI

      10.1111/his.13866

    • Peer Reviewed / Open Access
  • [Journal Article] Identification of specific microRNAs in neutrophils of type 2 diabetic mice : overexpression of microRNA-129-2-3p accelerates diabetic wound healing.2019

    • Author(s)
      Umehara T, Mori R, Mace K, Murase T, Abe Y, Yamamoto T, Ikematsu K
    • Journal Title

      Diabetes

      Volume: 68 Issue: 3 Pages: 617-630

    • DOI

      10.1124/jpet.118.253922

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Cap-specific terminal N6-methylation of RNA by an RNA polymerase Ⅱ-associated methyltransferase Cap.2019

    • Author(s)
      Akichika S., Hirano S., Shichino Y., Suzuki T., Nishimasu H., Ishitani R., Sugita A., Hirose Y., Iwasaki S., Nureki O., and Suzuki T.
    • Journal Title

      Science

      Volume: 11 Issue: 363 Pages: 6423

    • DOI

      10.1126/science.aav0080

    • Peer Reviewed
  • [Journal Article] CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy.2019

    • Author(s)
      Kimura H, Yamamoto H, Harada T, Fumoto K, Osugi Y, Sada R, Maehara N, Hikita H, Mori S. Eguchi H, Ikawa M, Takehara T, Kikuchi A.
    • Journal Title

      Clin Cancer Res.

      Volume: 25 Pages: 1936-1947

    • DOI

      10.1158/1078-0432.CCR-18-2124

    • Peer Reviewed
  • [Journal Article] Chemically modified antisense oligonucleotide against ARL4C inhibits primary and metastatic liver tumorgrowth.2019

    • Author(s)
      Harada, T., Matsumoto, S., Hirota, S., Kimura, H., Fujii, S., Kasahara, Y., Gon, H., Yoshida, T., Itoh, T., Haraguchi, N., Mizushima, T., Noda, T., Eguchi, H., Nojima, S., Morii, E., Fukumoto, T., Obika, S., Kikuchi, A.
    • Journal Title

      Mol. Cancer Ther.

      Volume: 18 Pages: 602-612

    • DOI

      10.1158/1535-7163.MCT-18-082

    • Peer Reviewed
  • [Journal Article] Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells.2019

    • Author(s)
      Shimizu H., Takeishi S., Nakatsumi H., Nakayama KI.
    • Journal Title

      JCI Insight

      Volume: 4 Pages: pii-125138

    • DOI

      10.1172/jci.insight.125138

    • Peer Reviewed / Open Access
  • [Journal Article] Motor skills mediated through cerebellothalamic tracts projecting to the central lateral nucleus.2019

    • Author(s)
      Nobuyuki Sakayori, Shigeki Kato, Masateru Sugawara, Susumu Setogawa, Hotaka Fukushima, Rie Ishikawa, Satoshi Kida, Kazuto Kobayashi
    • Journal Title

      Molecular Brain

      Volume: 12 Issue: 13

    • DOI

      10.1186/s13041-019-0431-x

    • Peer Reviewed / Open Access
  • [Journal Article] Motor skills mediated through cerebellothalamic tracts projecting to the central lateral nucleus2019

    • Author(s)
      Sakayori N, Kato S, Sugawara M, Setogawa S, Fukushima H, Ishikawa R, Kida S, Kobayashi K.
    • Journal Title

      Mol Brain

      Volume: 12 Pages: 13

    • DOI

      10.1186/s13041-019-0431-x

    • Peer Reviewed / Open Access
  • [Journal Article] A method of producing genetically manipulated mouse mammary gland2019

    • Author(s)
      Hiroaki Tagaya, Kosuke Ishikawa, Yoshito Hosokawa, Shun Kobayashi, Yukino Ueoka, Mayuna Shimada, Yasuko Ohashi, Hirofumi Mikami, Mizuki Yamamoto, Tatsuya Ihara, Kentaro Kumazawa, Kosuke Sugihara, Naoki Goshima, Shinya Watanabe and Kentaro Semba
    • Journal Title

      Breast Cancer Research

      Volume: 21 Pages: 1

    • DOI

      10.1186/s13058-018-1086-8

    • Peer Reviewed / Open Access
  • [Journal Article] High detection rate of MYD88 mutations in cerebrospinal fluid from patients with central nervous system lymphomas2019

    • Author(s)
      Jun Watanabe, Manabu Natsumeda, Masayasu Okada, Daiki Kobayashi, Yu Kanemaru, Yoshihiro Tsukamoto, Makoto Oishi, Akiyoshi Kakita, Yukihiko Fujii
    • Journal Title

      JCO Precision Oncology

    • DOI

      10.1200/PO.18.00308

    • Peer Reviewed
  • [Journal Article] Quinidine therapy and therapeutic drug monitoring in four patients with KCNTI mutations.2019

    • Author(s)
      Yoshitomi S, Takahashi Y, Yamaguchi T, Oboshi T, Horino A, Ikeda H, Imai K, Okanishi T, Nakashima M, Saitsu H, Matsumoto N, Yoshimoto J, Fujita T, Ishii A, Hirose S, Inoue Y.
    • Journal Title

      Epileptic Disorders

      Volume: 21 Issue: 1 Pages: 48-54

    • DOI

      10.1684/epd.2019.1026

    • Peer Reviewed
  • [Journal Article] EGFRvIII is Expressed in Cellular Areas of Tumor in a Subset of Glioblastoma2019

    • Author(s)
      Takanori NOZAWA, Masayasu OKADA, Manabu NATSUMEDA, Takeyoshi EDA, Hideaki ABE, Yoshihiro TSUKAMOTO, Kouichirou OKAMOTO, Makoto OISHI, Hitoshi TAKAHASHI, Yukihiko FUJII, and Akiyoshi KAKITA
    • Journal Title

      Neurologia medico-chirurgica (Tokyo)

      Volume: 59 Issue: 3 Pages: 89-97

    • DOI

      10.2176/nmc.oa.2018-0078

    • Peer Reviewed / Open Access
  • [Journal Article] Calvarial Bone Implantation and in vivo Imaging of Tumor Cells in Mice2019

    • Author(s)
      Hashimoto K, Sato S, Ochi H, Takeda S, Futakuchi M
    • Journal Title

      Bio Protoc

      Volume: 9 Issue: 3 Pages: e3151

    • DOI

      10.21769/BioProtoc.3151

    • Peer Reviewed / Open Access
  • [Journal Article] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.2019

    • Author(s)
      Imanishi, T., M. Unno, W. Kobayashi, N. Yoneda, S. Matsuda, K. Ikeda, T. Hoshii, A. Hirao, K. Miyake, G. N. Barber, M. Arita, K. J. Ishii, S. Akira, and T, Saito.
    • Journal Title

      Life Sci Alliance

      Volume: 2 Issue: 1 Pages: e201800282

    • DOI

      10.26508/lsa.201800282

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Opposing roles of dopamine receptor D1-and D2-expressing neurons in the anteromedial olfactory tubercle in acquisition of place preference in mice.2019

    • Author(s)
      Murata K, Kinoshita T, Fukazawa Y, Kobayashi K, Yamanaka A, Hikida T, Manabe H, Yamaguchi M.
    • Journal Title

      Front Behav Neurosci

    • DOI

      10.3389/fnbeh.2019.00050.eCollection2019

    • Peer Reviewed
  • [Journal Article] Synthesis and telomeric G-quadruplex-stabilizing ability of macrocyclic hexaoxazoles bearing three side chains2019

    • Author(s)
      Yue Ma, Keisuke Iida, Shogo Sasaki, Takatsugu Hirokawa, Heddi Brahim, Anh Tuan Phan, Kazuo Nagasawa
    • Journal Title

      Molecules

      Volume: 24 Pages: 263

    • DOI

      10.3390/molecules24020263

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] tChIP-Sea : cell-type-specific Eepigenome profiling2019

    • Author(s)
      Mito M, Kadota M., Nakagawa S. *, Iwasaki S. *
    • Journal Title

      J. Vis. Exp

      Volume: 143 Pages: e58298

    • DOI

      10.3791/58298

    • Peer Reviewed
  • [Journal Article] 悪性髄膜腫における個別化医療の可能性2019

    • Author(s)
      平石哲也、棗田学、岡田正康、大石誠、藤井幸彦
    • Journal Title

      Precision Medicine

      Volume: 2 Issue: 1 Pages: 54-58

  • [Journal Article] Magnetic hyperthermia using self-controlled heating elements consisting of Fe-Al milling alloy induces cancer cell apoptosis while preserving skeletal muscle2019

    • Author(s)
      Kawahara I, Goto K, Kodama K, Luo Y, Fujiwara-Tani R, Mori T, Miyagawa Y, Tanaka H, Kodama H, Hirayama A, Hosoito N, Taniguchi Y, Miki Y, Kuniyasu H
    • Journal Title

      Pathobiology

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Intracellular transport of NMDA receptors and Schizophrenia2019

    • Author(s)
      Yosuke Takei, Saki Tome, Tetsuya Sasaki
    • Journal Title

      Japanese Journal of Biological Psychiatry

    • Peer Reviewed
  • [Journal Article] p62/SQSTM1 : ‘Jack of all trades’ in health and cancer.2019

    • Author(s)
      Sánchez-Martin P, Saito T, Komatsu M.
    • Journal Title

      FEBS J.

      Volume: 286 Issue: 1 Pages: 8-23

    • DOI

      10.1111/febs.14712

    • Peer Reviewed / Open Access
  • [Journal Article] Parabrachial-to-amygdala control of aversive learning2019

    • Author(s)
      Nagase, M., Mikami, K., and Watabe, A. M. #(#責任著者)
    • Journal Title

      Current Opinion in Behavioral Sciences

      Volume: 26 Pages: 18-24

    • DOI

      10.1016/j.cobeha.2018.08.005

    • Peer Reviewed
  • [Journal Article] Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.2019

    • Author(s)
      Shirai F, Tsumura T, Yashiroda Y, Yuki H, Niwa H, Sato S, Chikada T, Koda Y, Washizuka K, Yoshimoto N, Abe M, Onuki T, Mazaki Y, Hirama C, Fukami T, Watanabe H, Honma T, Umehara T, Shirouzu M, Mizutani A, et al.
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 62 Issue: 7 Pages: 3407-3427

    • DOI

      10.1021/acs.jmedchem.8b01888

    • Peer Reviewed
  • [Journal Article] CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development.2019

    • Author(s)
      Shirai YT, Mizutani A, Nishijima S, Horie M, Kikuguchi C, Elisseeva O, Yamamoto T.
    • Journal Title

      Oncogene

      Volume: 38 Issue: 14 Pages: 2580-2594

    • DOI

      10.1038/s41388-018-0603-7

    • Peer Reviewed
  • [Journal Article] Encoding prediction signals during appetitive and aversive Pavlovian conditioning in the primate lateral hypothalamus.2019

    • Author(s)
      Noritake A, Nakamura K.
    • Journal Title

      Journal of neurophysiology

      Volume: 121 Issue: 2 Pages: 396-417

    • DOI

      10.1152/jn.00247.2018

    • Peer Reviewed
  • [Journal Article] Reward-enhancing effect of methylphenidate is abolished in dopamine transporter knockout mice : A model of attention-deficit/hyperactivity disorder.2018

    • Author(s)
      Ide S ; Ikekubo Y ; Hua J ; Takamatsu Y ; Uhi GR ; Sora I
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 38 Pages: 149-153

    • DOI

      10.1002/npr2.12020

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Growth cone phosphoproteomics reveals that GAP-43 phosphorylated by JNK is a marker of axon growth and regeneration.2018

    • Author(s)
      Asami Kawasaki*, Masayasu Okada*, Atsushi Tamada*, Shujiro Okuda, Motohiro Nozumi, Yasuyuki Ito, Daiki Kobayashi, Tokiwa Yamasaki, Ryo Yokoyama, Takeshi Shibata, Hiroshi Nishina, Yutaka Yoshida, Yukihiko Fujii, Kosei Takeuchi, Michihiro Igarashi (* : These three authors contributed equally)
    • Journal Title

      iSCIENCE

      Volume: 4 Pages: 190-203

    • DOI

      10.1016/j.isci.2018.05.019

    • Peer Reviewed / Open Access
  • [Journal Article] CDC42EP4, a perisynaptic scaffold protein in Bergmann glia, is required for glutamatergic tripartite synapse configuration.2018

    • Author(s)
      Ageta-Ishihara N, Konno K, Yamazaki M, Abe M, Sakimura K, Watanabe M, Kinoshita M.
    • Journal Title

      Neurochem Int

      Volume: 119 Pages: 190-198

    • DOI

      10.1016/j.neuint.2018.01.003

    • Peer Reviewed / Open Access
  • [Journal Article] Targeted expression of step-function opsins in transgenic rats for optogenetic studies.2018

    • Author(s)
      Igarashi H, Ikeda K, Onimaru H, Kaneko R, Koizumi K, Beppu K, Nishizawa K, Takahashi Y, Kato F, Matsui K, Kobayashi K, Yanagawa Y, Muramatsu SI, Ishizuka T, Yawo H
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 5435

    • DOI

      10.1038/s41598-018-23810-8

    • Peer Reviewed / Open Access
  • [Journal Article] Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells2018

    • Author(s)
      Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, Yamori T, Sugimoto Y, Seimiya H.
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: e14827

    • DOI

      10.1038/s41598-018-33139-x

    • Peer Reviewed / Open Access
  • [Journal Article] Resting-state functional connectivity analysis of the mouse brain using intrinsic optical signal imaging of cerebral blood volume dynamics2018

    • Author(s)
      Yuto Yoshida, Mitsuyuki Nakao, Norihiro Katayama
    • Journal Title

      Physiological Measurement

      Volume: 39 Pages: 054003

    • DOI

      10.1088/1361-6579/aac033

    • Peer Reviewed
  • [Journal Article] α-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 102018

    • Author(s)
      Huizi Li, Aya Sugyo, Atsushi Tsuji, Yukie Morokoshi, Katsuyuki Minegishi, Kotaro Nagatsu, Hiroaki Kanda, Yosuke Harada, Satoshi Nagayama, Toyomasa Katagiri, Yusuke Nakamura, Tatsuya Higashi, Sumitaka Hasegawa
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 7 Pages: 2302-2309

    • DOI

      10.1111/cas.13636

    • Peer Reviewed / Open Access
  • [Journal Article] Task-dependent function of striatal cholinergic interneurons2018

    • Author(s)
      Okada K, Nishizawa K, Setogawa S, Hashimoto K, Kobayashi K.
    • Journal Title

      Eur J Neurosci

      Volume: 47 Issue: 10 Pages: 1174-1183.

    • DOI

      10.1111/ejn.13768

    • Peer Reviewed
  • [Journal Article] Nuclear-cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXKI.2018

    • Author(s)
      Nakatsumi H., Oka T., Higa T., Shirane M., Nakayama KI.
    • Journal Title

      Genes Cells

      Volume: 23 Pages: 599-605

    • DOI

      10.1111/gtc.12597

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Quantitative study of the somatosensory sensitization underlying cross-modal plasticity.2018

    • Author(s)
      Abe K, Yawo H.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 12 Pages: e0208089

    • DOI

      10.1371/journal.pone.0208089

    • Peer Reviewed / Open Access
  • [Journal Article] Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior.2018

    • Author(s)
      Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, Matsumoto H, Miyakawa T, Nakada K.
    • Journal Title

      Journal of Neuroscience

      Volume: 39 Issue: 9 Pages: 1588-1604

    • DOI

      10.1523/JNEUROSCI.2139-18.2018

    • Peer Reviewed
  • [Journal Article] The temporal turning window for rat behavioral phenotypes by rotenone2018

    • Author(s)
      M. Ishido*
    • Journal Title

      Fund. Toxicol. Sci.

      Volume: 5 Pages: 195-202

    • DOI

      10.2131/fts.5.195

    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-l, a potential anti-cancer lead derived from debromoaplysiatoxin2018

    • Author(s)
      Hayakawa, K., Hanaki, Y., Tokuda, H., Yanagita, R. C., Nakagawa, Y., Okamura, M., Dan, S. and Irie, K.
    • Journal Title

      Heterocycles

      Volume: 97 Issue: 1 Pages: 478-492

    • DOI

      10.3987/COM-18-S(T)37

    • Peer Reviewed
  • [Journal Article] 眼位・瞳孔径変動を考慮した内因性光信号イメージングに基づく覚醒時マウス脳視野地図の推定2018

    • Author(s)
      外川 龍之介, 奥畑 大悟, 吉田 侑冬, 中尾 光之, 片山 統裕
    • Journal Title

      生体医工学

      Volume: 56 Issue: 4 Pages: 157-163

    • DOI

      10.11239/jsmbe.56.157

    • Peer Reviewed / Open Access
  • [Journal Article] Self-organizing cortex generated from human iPSCs with combination of FGF2 and ambient oxygen.2018

    • Author(s)
      Eguchi N, Sora I, Muguruma K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 498 Issue: 4 Pages: 729-735

    • DOI

      10.1016/j.bbrc.2018.03.049

    • Peer Reviewed / Open Access
  • [Journal Article] Longer telomeres in elderly schizophrenia are associated with long-term hospitalization in the Japanese population.2018

    • Author(s)
      Zhang Y ; Hishimoto A ; Otsuka I ; Watanabe Y ; Numata S ; Yamamori H ; Boku S ; Horai T ; Someya T ; Ohmori T ; Hashimoto R ; Sora I
    • Journal Title

      J Psychiatr Res

      Volume: 103 Pages: 161-166

    • DOI

      10.1016/j.jpsychires

    • Peer Reviewed / Open Access
  • [Journal Article] Area-specific modulation of functional cortical activity during block-based and trial-based proactive inhibition.2018

    • Author(s)
      Yoshida J, Saiki A, Soma S, Yamanaka K, Nonomura S, Rios A, Kawabata M, Kimura M, Sakai Y, *Isomura Y
    • Journal Title

      Neuroscience

      Volume: 388 Pages: 297-316

    • DOI

      10.1016/j.neuroscience.2018.07.039

    • Peer Reviewed
  • [Journal Article] Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.2018

    • Author(s)
      Okazaki S, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Boku S, Shimmyo N, Kinoshita M, Inoue E, Ohmori T, Someya T, Sora I.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 83 Pages: 33-41

    • DOI

      10.1016/j.pnpbp.2018.01.001

    • Peer Reviewed / Open Access
  • [Journal Article] Mitochondrial DNA copy number of peripheral blood in bipolar disorder : The present study and a meta-analysis.2018

    • Author(s)
      Yamaki N ; Otsuka I ; Numata S ; Yanagi M ; Mouri K ; Okazaki S ; Boku S ; Horai T ; Ohmori T ; Shirakawa O ; Sora I ; Hishimoto A
    • Journal Title

      Psychiatry Res

      Volume: 269 Pages: 115-117

    • DOI

      10.1016/j.psychres

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-12018

    • Author(s)
      Ida-Yonemochi H, Morita W, Sugiura N, Kawakami R, Morioka Y, Takeuchi Y, Sato T, Shibata S, Watanabe H, Imamura T, Igarashi M, Ohshima H, Takeuchi K
    • Journal Title

      Sci Rep

      Volume: 8 Pages: 17134

    • DOI

      10.1038/s41598-018-35412-5

    • Peer Reviewed / Open Access
  • [Journal Article] Formin homology 2 domain-containing 3 (Fhod3) controls neural plate morphogenesis in mouse cranial neurulation by regulating multidirectional apical constriction.2018

    • Author(s)
      Sulistomo HW, Nemoto T, Yanagita T, Takeya R.
    • Journal Title

      J Biol Chem

      Volume: 294 Pages: 2924-2934

    • DOI

      10.1074/jbc.RA118.005471

    • Peer Reviewed
  • [Journal Article] Superiority of rat over murine model for studies on the evolution of cancer genome.2018

    • Author(s)
      Akatsuka S, Li GH, Toyokuni S
    • Journal Title

      Free Radical Research

      Volume: 52 Pages: 1323-1327

    • DOI

      10.1080/10715762.2018.1467562

    • Peer Reviewed
  • [Journal Article] Loss of chromosome Y in blood, but not in brain, of suicide completers.2018

    • Author(s)
      Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 1 Pages: e0190667

    • DOI

      10.1371/journal.pone.0190667

    • Peer Reviewed / Open Access
  • [Journal Article] A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients.2018

    • Author(s)
      Horai T, Hishimoto A, Otsuka I, So T, Mouri K, Shimmyo N, Boku S, Okishio N, Sora I.
    • Journal Title

      Neuropsychiatr Dis Treat

      Volume: 14 Pages: 663-669

    • DOI

      10.2147/NDT.S153360

    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of chromosome Y loss in men with schizophrenia.2018

    • Author(s)
      Hirata T ; Hishimoto A ; Otsuka I ; Okazaki S ; Kimura A ; Horai T ; Sora I
    • Journal Title

      Neuropsychiatr Dis Treat

      Volume: 14 Pages: 2115-2122

    • DOI

      10.2147/NDT.S172886

    • Peer Reviewed / Open Access
  • [Journal Article] MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas and MGMT Silencing to Temozolomide Sensitivity in IDH-Mutant Gliomas2018

    • Author(s)
      Hideaki ABE, Manabu NATSUMEDA, Yu KANEMARU, Jun WATANABE, Yoshihiro TSUKAMOTO, Masayasu OKADA, Junichi YOSHIMURA, Makoto OISHI, and Yukihiko FUJII
    • Journal Title

      Neurol Med Chir (Tokyo)

      Volume: 58 Pages: 290-295

    • DOI

      10.2176/nmc.ra.2018-0044

    • Peer Reviewed
  • [Journal Article] Neurocognitive Impairments Are More Severe in the Binge-Eating/Purging Anorexia Nervosa Subtype Than in the Restricting Subtype.2018

    • Author(s)
      Tamiya Y ; Ouchi A ; Chen R ; Miyazawa S ; Akimoto Y ; Kaneda Y ; Sora I
    • Journal Title

      Front Psychiatry

      Volume: 138 Pages: 9

    • DOI

      10.3389/fpsyt.2018.00138

    • Peer Reviewed / Open Access
  • [Journal Article] Larger Numbers of Glial and Neuronal Cells in the Periaqueductal Gray Matter of μ-Opioid Receptor Knockout Mice.2018

    • Author(s)
      Sasaki K ; Hall FS ; Uhl GR ; Sora I
    • Journal Title

      Front Psychiatry

      Volume: 9 Pages: 441

    • DOI

      10.3389/fpsyt.2018.00441

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Gamma-aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain : An exploratory study.2018

    • Author(s)
      Yokoshima Y, Sumitani M, Nishizawa D, Nagashima M, Ikeda K, Kato R, Hozumi J, Abe H, Azuma K, Tsuchida R, Yamada Y, Japanese TR-Cancer Pain Research Group.
    • Journal Title

      Neuropsychopharmacology Report

      Volume: 38 Pages: 175-181

    • DOI

      10.1002/npr2.12030

    • Peer Reviewed
  • [Journal Article] 3D culture system containing gellan gum restores oncogene dependence in ROSI rearrangements non-small cell lung cancer.2018

    • Author(s)
      Gong, B., Oh-Hara, T., Fujita, N. and *Katayama, R.
    • Journal Title

      Biochem. Biophys. Res. Commun.,

      Volume: 501 Pages: 527-533

    • DOI

      10.1016/j.bbrc.2018.05.031

    • Peer Reviewed
  • [Journal Article] A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice.2018

    • Author(s)
      Zhang Y, Nakano D, Guan Y, Hitomi H, Masaki T, Kobara H, Sugaya Y, Nishiyama A.
    • Journal Title

      Kidney Int.

      Volume: 94 Issue: 3 Pages: 524-535

    • DOI

      10.1016/j.kint.2018.05.002

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCNIA gene.2018

    • Author(s)
      Tanaka Y, Higurashi N, Shirasu N, Yasunaga S, Moreira KM, Okano H, Hirose S.
    • Journal Title

      Stem Cell Research

      Volume: 31 Pages: 11-15

    • DOI

      10.1016/j.scr.2018.06.008

    • Peer Reviewed / Open Access
  • [Journal Article] Persistent Pleural Lesions and Inflammation by Pulmonary Exposure of Multiwalled Carbon Nanotubes2018

    • Author(s)
      Liao D, Wang Q, He J, Alexander DB, Abdelgied M, El-Gazzar AM, Futakuchi M, Suzui M, Kanno J, Hirose A, Xu J, Tsuda H
    • Journal Title

      Chem Res Toxicol

      Volume: 31 Issue: 10 Pages: 1025-1031

    • DOI

      10.1021/acs.chemrestox.8b00067

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm : association with immunoblastoid cytomorphology, MYC expression, and drug response.2018

    • Author(s)
      Sakamoto, K., Katayama, R., Asaka, R., Sakata, S., Baba, S., Nakasone, H., Takakuwa, E., Yamazaki, R., Takizawa, J., Maeda, T., Narita, M., Izutsu, K., Kanda, Y., Ohshima, K, and *Takeuchi, K.,
    • Journal Title

      Leukemia

      Volume: 32 Pages: 2590-2603

    • DOI

      10.1038/s41375-018-0154-5

    • Peer Reviewed / Open Access
  • [Journal Article] Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells.2018

    • Author(s)
      Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Toyoda Y, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama S
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 6760

    • DOI

      10.1038/s41598-018-25189-y

    • Peer Reviewed / Open Access
  • [Journal Article] p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adpocytes and cancer cells.2018

    • Author(s)
      Nagano H, Hashimoto N, Nakayama A, Suzuki S, Miyabayashi Y, Yamato A, Higuchi S, Fujimoto M, Sakuma I, Beppu M, Yokoyama M, Suzuki Y, Sugano S, Ikeda K, Tatsuno I, Manabe I, Yokote K, Inoue S, Tanaka T.
    • Journal Title

      Proc Natl Acad Sci USA.

      Volume: 115 Issue: 33 Pages: 8370-8375

    • DOI

      10.1073/pnas.1804243115

    • Peer Reviewed / Open Access
  • [Journal Article] A new method for identifying mouse pancreatic ducts2018

    • Author(s)
      Nakajima C, Kamimoto K, Miyajima K, Matsumoto M, Okazaki Y, Kobayashi-Hattori K, Shimizu M, Yamane T, Oishi Y, Iwatsuki K.
    • Journal Title

      Tissue Eng.

      Volume: 24 Issue: 8 Pages: 480-485

    • DOI

      10.1089/ten.tec.2018.0127

    • Peer Reviewed / Open Access
  • [Journal Article] MicroRNA-137-mediated Src oncogenic signaling promotes cancer progression2018

    • Author(s)
      Kokuda R, Watanabe R, Okuzaki D, Akamatsu H, Oneyama C.
    • Journal Title

      Genes Cells

      Volume: 23 Issue: 8 Pages: 688-701

    • DOI

      10.1111/gtc.12610

    • Peer Reviewed / Open Access
  • [Journal Article] FEAT enhances INSL3 expression in testicular Leydig cells.2018

    • Author(s)
      Li Y, Kobayashi K, Murayama K, Kawahara K, Shima Y, Suzuki A, Tani K, Takahashi A.
    • Journal Title

      Genes to cells

      Volume: 23 Pages: 952-962

    • DOI

      10.1111/gtc.12644

    • Peer Reviewed
  • [Journal Article] A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of in vitro and in silico analyses.2018

    • Author(s)
      Kamijo Y, Kawahara K, Yoshinaga T, Kurata H, Arima K, Furukawa T.
    • Journal Title

      Oncoscience.

      Volume: 5 Pages: 88-98

    • DOI

      10.18632/oncoscience.411

    • Peer Reviewed / Open Access
  • [Journal Article] Therapeutic and Preventive Effects of Osteoclastogenesis Inhibitory Factor on Osteolysis, Proliferation of Mammary Tumor Cell and Induction of Cancer Stem Cells in the Bone Microenvironment2018

    • Author(s)
      Futakuchi M, Nitanda T, Ando S, Matsumoto H, Yoshimoto E, Fukamachi K, Suzui M
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 3

    • DOI

      10.3390/ijms19030888

    • Peer Reviewed / Open Access
  • [Journal Article] Steroid sulfatase promotes invasion through epithelial-mesenchymal transition and predicts the progression of bladder cancer.2018

    • Author(s)
      Shimizu Y1, Tamada S1, Kato M1, Takeyama Y1, Fujioka M2, Kakehashi A2, Nakatani T1, Wanibuchi H2, Gi M2.
    • Journal Title

      Exp Ther Med

      Volume: 16 Issue: 6 Pages: 4463-4470

    • DOI

      10.3892/etm.2018.6787

    • Peer Reviewed
  • [Journal Article] An Overview of Development of Quantitative Neurotoxicity Testing In vitro2018

    • Author(s)
      M. Ishido*
    • Journal Title

      J. Applied Life Sci. Intl.

      Volume: 19 Pages: 2394-1103

    • DOI

      10.9734/JALSI/2018/45377

    • Peer Reviewed / Open Access
  • [Journal Article] 細胞突起形成抑制による膠芽腫治療戦略2018

    • Author(s)
      岡田正康, 棗田学, 河嵜麻実, 大石誠, 藤井幸彦, 五十嵐道弘
    • Journal Title

      新潟県医師会報

      Volume: 814 Issue: 1 Pages: 9-10

    • Peer Reviewed
  • [Journal Article] マンガの読みにおける状況モデルの更新2018

    • Author(s)
      和田裕一, 三浦知志, 窪俊一
    • Journal Title

      マンガ研究

      Volume: 24 Pages: 93-114

    • Peer Reviewed
  • [Journal Article] Spredl Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.2018

    • Author(s)
      Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A
    • Journal Title

      Cell Stem Cell

      Volume: 22 Pages: 713-725

    • DOI

      10.1016/j.stem.2018.04.002

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dobutamine treatment reduces inflammation in the preterm fetal sheep brain exposed to acute hypoxia2018

    • Author(s)
      Brew N, Nakamura S, Hale, N. Azhan, A., Davies, G. I. Nitsos, I., Miller, S. I., Walker, D. W., Wong, F. Y.
    • Journal Title

      Pediatr Res

      Volume: 83 Issue: 3 Pages: 442-450

    • DOI

      10.1038/s41390-018-0045-5

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mitochondrial pyruvate carrier I expression controls cancer EMT and radioresistance.2018

    • Author(s)
      Takaoka, Y., Konno, M., Koseki, J., Colvin, H., Asai, A., Tamari, K., Satoh, T., Mori, M., Doki, Y., Ogawa, K., Ishii, H.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 4 Pages: 1331-1339

    • DOI

      10.1111/cas.13980

    • Peer Reviewed / Open Access
  • [Journal Article] Immediate-early promoter-driven transgenic reporter system for neuroethological researches in a hemimetabolous insect2018

    • Author(s)
      Watanabe T., Ugajin A. and Aonuma H.
    • Journal Title

      eNeuro

      Volume: 5 Pages: e0016-18

    • DOI

      10.1523/ENEURO.0061-18.2018

    • Peer Reviewed
  • [Journal Article] Parallel arousal pathways in the lateral hypothalamus.2018

    • Author(s)
      Heiss JE, Yamanaka A, Kilduff TS.
    • Journal Title

      eNeuro

      Volume: 5 Pages: 0228-18

    • DOI

      10.1523/ENEURO.0228-18.2018

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A stable association with PME-1 may be dispensable for PP2A demethylation-implications for the detection of PP2A methylation and immunoprecipitation2018

    • Author(s)
      Yabe R. Tsuji S, Mochida S, Ikehara T, Usui T, Ohama T*, Sato K
    • Journal Title

      FEBS Open Bio

      Volume: 8 Issue: 9 Pages: 1486-1496

    • DOI

      10.1002/2211-5463.12485

    • Peer Reviewed / Open Access
  • [Journal Article] β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.2018

    • Author(s)
      Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H.
    • Journal Title

      PLoS ONE

      Volume: 13 Issue: 5 Pages: e0196946

    • DOI

      10.1371/journal.pone.0196946

    • Peer Reviewed / Open Access
  • [Journal Article] Glycans in stem cell regulation : from Drosophila tissue stem cells to mammalian pluripotent stem cells.2018

    • Author(s)
      Nishihara S
    • Journal Title

      FEBS Lett.

      Volume: 592 Issue: 23 Pages: 3773-3790

    • DOI

      10.1002/1873-3468.1316

    • Peer Reviewed
  • [Journal Article] Structural basis for species-specific activation of mouse Toll-like receptor 9.2018

    • Author(s)
      Ishida, H., U. Ohto, T. Shibata, K, Miyake, and T. Shimizu.
    • Journal Title

      FEBS Lett

      Volume: 592 Issue: 15 Pages: 2636-2646

    • DOI

      10.1002/1873-3468.13176

    • Peer Reviewed / Open Access
  • [Journal Article] Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound2018

    • Author(s)
      Shadi Sedghi Masoud, Yudai Yamaoki, Yue Ma, Adrian Marchand, Fernaldo Richtia Winnerdy, Valerie Gabelica, Anh Tuan Phan, Masato Katahira & Kazuo Nagasawa
    • Journal Title

      ChemBioChem

      Volume: 19 Pages: 2268-2272

    • DOI

      10.1002/cbic.201800425

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Platelet-Derived TGF-β Induces Tissue Factor Expression via the Smad3 Pathway in Osteosarcoma Cells.2018

    • Author(s)
      Saito M, Ichikawa J, Ando T. Schoenecker JG, Ohba T, Koyama K, Suzuki-Inoue K, Haro H.
    • Journal Title

      J Bone Miner Res.

      Volume: 33 Issue: 11 Pages: 2048-2058

    • DOI

      10.1002/jbmr

    • Peer Reviewed
  • [Journal Article] Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation2018

    • Author(s)
      Masaya Baba, Mitsuhiro Endoh. Wenjuan Ma, Hirofumi Toyama. Akiyoshi Hirayama, Keiyo Takubo, Hiroyuki Hano. Hisashi Hasumi, Terumasa Umemoto, Michihiro Hashimoto, Nobuko Irie, Chiharu Esumi, Miho Kataoka, Naomi Nakagata, Tomoyoshi Soga, Masahiro Yao, Tomomi Kamba, Takashi Minami, Masaru Ishii, Toshio Suda
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 33 Issue: 10 Pages: 1785-1798

    • DOI

      10.1002/jbmr.3477

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] HipOP mesenchymal population has high potential for repairing injured peripheral nerves.2018

    • Author(s)
      Yamauchi Y., Itoh S, et al.
    • Journal Title

      J. Cell Biochem.

      Volume: 119 Issue: 6 Pages: 4836-4844

    • DOI

      10.1002/jcb.26684

    • Peer Reviewed
  • [Journal Article] Identification of proteolytic cleavage sites of EphA2 by membrane type-1 matrix metalloproteinase on the surface of cancer cells2018

    • Author(s)
      Kikuchi K, Kozuka-Hata H, Oyama M, Seiki M & Koshikawa N
    • Journal Title

      Methods in Molecular Biology

      Volume: 1731 Pages: 29-37

    • DOI

      10.1007/978-1-4939-7595-2_3

    • Peer Reviewed
  • [Journal Article] Salll regulates microglial morphology cell autonomously in the developing retina2018

    • Author(s)
      Koso H, Nishinakamura R, Watanabe S
    • Journal Title

      Adv Exp Med Biol

      Volume: 1074 Pages: 209-215

    • DOI

      10.1007/978-3-319-75402-4_26

    • Peer Reviewed
  • [Journal Article] Tyraminergic modulation of agonistic outcomes in crayfish2018

    • Author(s)
      Momohara Y., Aonuma H. and Nagayama T.
    • Journal Title

      J. Comp. Physiol.

      Volume: 204 Pages: 465-473

    • DOI

      10.1007/s00359-018-1255-3

    • Peer Reviewed
  • [Journal Article] NIPA-like domain containing l is a novel tumor-promoting factor in oral squamous cell carcinoma.2018

    • Author(s)
      Sasahira T. Nishiguchi Y. Kurihara-Shimomura M, Nakashima C, Kuniyasu H, Kirita T.
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 144 Issue: 5 Pages: 875-882

    • DOI

      10.1007/s00432-018-2612-x

    • Peer Reviewed
  • [Journal Article] Alterations in the reduced pteridine contents in the cerebrospinal fluids of LRRK2 mutation carriers and patients with Parkinson's disease.2018

    • Author(s)
      Ichinose H, Inoue KI. Arakawa S. Watanabe Y, Kurosaki H, Koshiba S, Hustad E, Takada M, Aasly JO
    • Journal Title

      J Neural Transm

      Volume: 125 Pages: 45-52

    • DOI

      10.1007/s00702-017-1784-x

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Systematic review of pre-clinical chronic myeloid leukaemia.2018

    • Author(s)
      Kuan JW, Su AT, Leong CF, Osato M, Sashida G.
    • Journal Title

      Int J Hematol.

      Volume: 108 Issue: 5 Pages: 465-484

    • DOI

      10.1007/s12185-018-2528-x

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Multiple Phases of Climbing Fiber Synapse Elimination in the Developing Cerebellum.2018

    • Author(s)
      Kano M, Watanabe T, Uesaka N, Watanabe M.
    • Journal Title

      Cerebellum.

      Volume: 17 Issue: 6 Pages: 722-734

    • DOI

      10.1007/s12311-018-0964-z

    • Peer Reviewed
  • [Journal Article] Regulation of mitochondrial iron homeostasis by sideroflexin 22018

    • Author(s)
      Non, E.E., *Wei, F.-Y., Ahmad, R.N.R., Yamamoto, T., Moroishi. T., *Tomizawa, K.
    • Journal Title

      J. Physiol. Sci.

      Volume: 69 Pages: 359-373

    • DOI

      10.1007/s12576-018-0652-2

    • Peer Reviewed / Open Access
  • [Journal Article] Biallelic Variants in CNPY3. Encoding an Endoplasmic Reticulum Chaperone, Cause Early-Onset Epileptic Encephalopathy.2018

    • Author(s)
      Mutoh, H., M. Kato. T. Akita, T. Shibata, H. Wakamoto, H. Ikeda, H. Kitaura, K. Aoto, M. Nakashima, T. Wang, C. Ohba, S. Miyatake, N. Miyake, A. Kakita, K. Miyake, A. Fukuda, N. Matsumoto, and H. Saitsu.
    • Journal Title

      Am J Hum Genet

      Volume: 102 Issue: 2 Pages: 321-329

    • DOI

      10.1016/j.ajhg.2018.01.004

    • Peer Reviewed / Open Access
  • [Journal Article] Transglutaminase-mediated cross-linking of WDR54 regulates EGF receptor-signaling.2018

    • Author(s)
      Maeda A. Nishino T, Matsuzaki R, Yokoyama A, Suga H, Yagi T, Konishi H.
    • Journal Title

      Biochim Biophys Acta Mol Cell Res.

      Volume: 1866 Pages: 285-295

    • DOI

      10.1016/j.bbamcr.2018.11.009

    • Peer Reviewed / Open Access
  • [Journal Article] The role of Zhx2 transcription factor in bipolar cell differentiation during mouse retinal development2018

    • Author(s)
      Kawamura Y, Yamanaka K, Poh B, Kuribayashi H. Koso H, Watanabe S
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 503 Issue: 4 Pages: 3023-3030

    • DOI

      10.1016/j.bbrc.2018.08.088

    • Peer Reviewed
  • [Journal Article] Further characterization of CAPOS/CAOS syndrome with the Glu818Lys mutation in the ATP1A3 gene : A case report.2018

    • Author(s)
      Hayashida T, Saito Y, Ishii A, Hirose S, Hiraiwa R. Maegaki Y, Ohno K.
    • Journal Title

      Brain & Development

      Volume: 40 Issue: 7 Pages: 576-581

    • DOI

      10.1016/j.braindev.2018.03.004

    • Peer Reviewed
  • [Journal Article] Relationship between prolonged neural suppression and cerebral hemodynamic dysfunction during hypothermia in asphyxiated piglels2018

    • Author(s)
      Jinnai, W. Nakamura, S. Koyano, K. Yamato, S. Wakabayashi, T. Htun, Y. Nakao, Y. Iwase, T. Nakamura, M. Yasuda, S. Ueno, M. Miki, T. Kusaka T
    • Journal Title

      Brain Dev

      Volume: 40 Issue: 8 Pages: 649-661

    • DOI

      10.1016/j.braindev.2018.04.010

    • Peer Reviewed
  • [Journal Article] A patient with a GNAOI mutation with decreased spontaneous movements, hypotonia, and dystonic features.2018

    • Author(s)
      Okumura A. Naruyama K, Shibata M, Kurahashi H, Ishii A, Numoto S, Hirose S, Kawai T, Iso M, Kataoka S, Okuno Y, Muramatsu H, Kojima S.
    • Journal Title

      Brain & Development

      Volume: 40 Issue: 10 Pages: 926-930

    • DOI

      10.1016/j.braindev.2018.06.005

    • Peer Reviewed
  • [Journal Article] The autism-related protein CHD8 cooperates with C/EBP β to regulate adipogenesis.2018

    • Author(s)
      Kita Y., Katayama Y., Shiraishi T., Oka T., Sato T., Suyama M., Ohkawa Y., Miyata K., Oike Y., Shirane M., Nishiyama M., Nakayama KI.
    • Journal Title

      Cell Rep.

      Volume: 23 Pages: 1988-2000

    • DOI

      10.1016/j.celrep.2018.04.050

    • Peer Reviewed / Open Access
  • [Journal Article] Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells.2018

    • Author(s)
      Hirotaka Watanabe, et al.
    • Journal Title

      Cell Reports

      Volume: 23 Pages: 3721-3729

    • DOI

      10.1016/j.celrep.2018.05.081

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents.2018

    • Author(s)
      Tainaka K. Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T. Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A. Ueda HR.
    • Journal Title

      Cell Reports

      Volume: 24 Pages: 2196-2210

    • DOI

      10.1016/j.celrep.2018.07.056

    • Peer Reviewed / Open Access
  • [Journal Article] Calcium transient dynamics of neural ensembles in the primary motor cortex of naturally behaving monkeys.2018

    • Author(s)
      Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF. Ushiba J. Okano H.
    • Journal Title

      Cell Rep

      Volume: 24 Issue: 8 Pages: 2191-2195

    • DOI

      10.1016/j.celrep.2018.07.057

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output2018

    • Author(s)
      Hashimotodani Y, Karube F, Yanagawa Y, Fujiyama F, Kano M
    • Journal Title

      Cell Rep.

      Volume: 25 Pages: 2704-2715

    • DOI

      10.1016/j.celrep.2018.11.016

    • Peer Reviewed / Open Access
  • [Journal Article] Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.2018

    • Author(s)
      Zhang, Z., U. Ohto, T. Shibata, M. Taoka, Y. Yamauchi, R. Sato, N. M. Shukla, S. A. David, T. Isobe, K. Miyake, and T. Shimizu.
    • Journal Title

      Cell Rep

      Volume: 25 Issue: 12 Pages: 3371-3381

    • DOI

      10.1016/j.celrep.2018.11.081

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.2018

    • Author(s)
      Maruzuru, Y., T. Ichinohe, R. Sato, K. Miyake, T. Okano, T. Suzuki. T. Koshiba, N. Koyanagi, S. Tsuda, M. Watanabe, J. Arii, A. Kato, and Y. Kawaguchi.
    • Journal Title

      Cell Host Microbe

      Volume: 23 Issue: 2 Pages: 254-265

    • DOI

      10.1016/j.chom.2017.12.014

    • Peer Reviewed / Open Access
  • [Journal Article] CD4+ CD521o T-cell expression contributes to the development of systemic lupus erythematosus2018

    • Author(s)
      Umeda M, Koga T, Ichinose K, Igawa T, Sato T, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Birai Y, Kawashiri S. -Y. Iwamoto N, Aramaki T, Tamai M, Nakamura H, Yamamoto K, Abiru N, Origuchi T, Ueki Y and Kawakami A
    • Journal Title

      Clinical Immunology

      Volume: 187 Pages: 50-57

    • DOI

      10.1016/j.clim.2017.10.004

    • Peer Reviewed / Open Access
  • [Journal Article] Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2.2018

    • Author(s)
      Hashimoto Y, Hata T, Tada M, Iida M, Watari A, Okada Y, Doi T, Kuniyasu H, Yagi K, Kondoh M
    • Journal Title

      Eur J Pharm Sci

      Volume: 117 Pages: 161-167

    • DOI

      10.1016/j.ejps.2018.02.016

    • Peer Reviewed
  • [Journal Article] Recurrent autonomic and sensory neuropathy in a patient with anti-ganglionic acetylcholine receptor antibodies.2018

    • Author(s)
      Watanabe E, Fujita T, Shimono M, Koike H, Yasumoto S, Hirose S.
    • Journal Title

      eNeurologicalSci

      Volume: 12 Pages: 36-38

    • DOI

      10.1016/j.ensci.2018.08.001

    • Peer Reviewed / Open Access
  • [Journal Article] Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation.2018

    • Author(s)
      Ohto, U., H. Ishida, T. Shibata, R. Sato, K. Miyake, and T. Shimizu.
    • Journal Title

      Immunity

      Volume: 48 Issue: 4 Pages: 649-658

    • DOI

      10.1016/j.immuni.2018.03.013

    • Peer Reviewed / Open Access
  • [Journal Article] The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.2018

    • Author(s)
      Pelka, K., D. Bertheloot, E. Reimer, K. Phulphagar, S. V. Schmidt, A, Christ, R. Stahl. N. Watson, K. Miyake, N. Hacohen, A. Haas, M. M. Brinkmann, A. Marshak-Rothstein, F. Meissner, and E. Latz.
    • Journal Title

      Immunity

      Volume: 48 Issue: 5 Pages: 911-922

    • DOI

      10.1016/j.immuni.2018.04.011

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ezhl Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.2018

    • Author(s)
      Aoyama K, Oshima M, Koide S, Suzuki E, Mochizuki-Kashio M, Kato Y, Tara S, Shinoda D, Hiura N, Nakajima-Takagi Y, Sashida G, Iwama A.
    • Journal Title

      iScience

      Volume: 9 Pages: 161-174

    • DOI

      10.1016/j.isci.2018.10.008

    • Peer Reviewed / Open Access
  • [Journal Article] USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.2018

    • Author(s)
      Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M. Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.
    • Journal Title

      iScience.

      Volume: 9 Pages: 433-450

    • DOI

      10.1016/j.isci.2018.11.006

    • Peer Reviewed / Open Access
  • [Journal Article] In-frame Va1216-Ser217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response2018

    • Author(s)
      Hattori M, Ishikawa O. Oikawa D, Amano H, Yasuda M, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Terawaki SI, Wakamatsu K, Tokunaga F, Shimizu A.
    • Journal Title

      Journal of Dermatological Science

      Volume: 91 Issue: 1 Pages: 35-42

    • DOI

      10.1016/j.jdermsci.2018.03.012

    • Peer Reviewed
  • [Journal Article] LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.2018

    • Author(s)
      Tsukahara, R., Yamamoto, S., Yoshikawa, K., Gotoh, M., Tsukahara, T., Neyama, H., Ishii, S., Akahoshi, N., Yanagida, K., Sumida, H., Araki, M., Araki, K., Yamamura, K. I., Murakami-Murofushi, K., Ueda, H.
    • Journal Title

      J. Pharmacol. Sci.

      Volume: 136 Pages: 93-96

    • DOI

      10.1016/j.jphs.2018.01.001

    • Peer Reviewed / Open Access
  • [Journal Article] Monitoring and updating of action selection for goal-directed behavior through the striatal direct and indirect pathways2018

    • Author(s)
      Nonomura S, Nishizawa K, ……, Ogawa M, et al.
    • Journal Title

      Neuron

      Volume: 99 Issue: 6 Pages: 1302-1314

    • DOI

      10.1016/j.neuron.2018.08.002

    • Peer Reviewed
  • [Journal Article] Acute aversive stimuli rapidly increase the activity of ventral tegmental area dopamine neurons in awake mice.2018

    • Author(s)
      Moriya S, Yamashita A. Kawashima S, Nishi R, Yamanaka A, Kuwaki T.
    • Journal Title

      Neuroscience

      Volume: 386 Pages: 16-23

    • DOI

      10.1016/j.neuroscience.2018.06.027

    • Peer Reviewed
  • [Journal Article] Reappraising newborn screening for cobalamin C disorder.2018

    • Author(s)
      Tocan V. Ohkubo K, Higashi K, Toda N, Kojima-Ishii K, Nishiyama K, Ishimura M, Takada H, Sakamoto O, Sasaki F, Yoshimura K, Hirose S, Ohga S.
    • Journal Title

      Pediatrics & Neonatology

      Volume: 59 Issue: 4 Pages: 415-417

    • DOI

      10.1016/j.pedneo.2017.11.002

    • Peer Reviewed / Open Access
  • [Journal Article] Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia2018

    • Author(s)
      Yukawa t, Iwakura Y, Takei N, Saito M, Watanabe Y, Toyooka K, Igarashi, M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Iritani S, Niwa S, Takeuchi R. Takahashi H, Kakita A, Someya T, *Nawa H
    • Journal Title

      Psychiarty Res

      Volume: 270 Pages: 940-946

    • DOI

      10.1016/j.psychres.2018.10.062

    • Peer Reviewed
  • [Journal Article] Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men.2018

    • Author(s)
      Fink J, Matsumoto M, Tamura Y.
    • Journal Title

      Steroids

      Volume: 161 Pages: 161-166.

    • DOI

      10.1016/j.steroids.2018.08.002

    • Peer Reviewed / Open Access
  • [Journal Article] Intracellular redox status controls spherogenicity, an in vitro cancer stem cell marker, in thyroid cancer cell lines2018

    • Author(s)
      Shimamura M, Yamamoto K, Kurashige T, Nagayama Y
    • Journal Title

      Experimental Cell research

      Volume: 370 Issue: 2 Pages: 699-707

    • DOI

      10.1016/j.yexcr.2018.07.036

    • Peer Reviewed / Open Access
  • [Journal Article] Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling.2018

    • Author(s)
      Takeuchi Y., Kito A., et al.
    • Journal Title

      Exp. Cell Res.

      Volume: 371 Issue: 2 Pages: 417-425

    • DOI

      10.1016/j.yexcr.2018.09.002

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Red-Tuning of the Channelrhodopsin Spectrum Using Long Conjugated Retinal Analogues.2018

    • Author(s)
      Shen YC, Sasaki T, Matsuyama T, Yamashita T, Shichida Y, Okitsu T, Yamano Y, Wada A, Ishizuka T, Yawo H, Imamoto Y.
    • Journal Title

      Biochemisty

      Volume: 57 Issue: 38 Pages: 5544-5556

    • DOI

      10.1021/acs.biochem.8b00583

    • Peer Reviewed
  • [Journal Article] Chiroptical Inversion of Europium(Ⅲ) Complexes by Changing a Remote Stereogenic Center of a C2-symmetric Bispyrrolidinoindoline Manifold2018

    • Author(s)
      Tomoaki Taniguchi, Akira Tsubouchi, Yuki Imai, Junpei Yuasa, Hiroki Oguri
    • Journal Title

      J. Org. Chem.

      Volume: 83 Issue: 24 Pages: 15284-15296

    • DOI

      10.1021/acs.joc.8b02550

    • Peer Reviewed
  • [Journal Article] Design and De Novo Synthesis of 6-Aza-artemisinins2018

    • Author(s)
      Karnakar Reddy Bonepally, Takahisa Hiruma, Haruki Mizoguchi, Kyohei Ochiai, Shun Suzuki, Hideaki Oikawa, Aki Ishiyama, Rei Hokari, Masato Iwatsuki, Kazuhiko Otoguro, Satoshi Omura, Hiroki Oguri
    • Journal Title

      Org. Lett.

      Volume: 20 Issue: 15 Pages: 4667-4671

    • DOI

      10.1021/acs.orglett.8b01987

    • Peer Reviewed
  • [Journal Article] Chemo-enzymatic Total Syntheses of Jorunnamycin A, Saframycin A. and N-Fmoc Saframycin Y32018

    • Author(s)
      Ryo Tanifuji, Kento Koketsu, Michiko Takakura, Ryutaro Asano, Atsushi Minami, Hideaki Oikawa, Hiroki Oguri
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 140 Issue: 34 Pages: 10705-10709

    • DOI

      10.1021/jacs.8b07161

    • Peer Reviewed
  • [Journal Article] Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-Ⅲ and Racl.2018

    • Author(s)
      Ahmat Amin MKB, Shimizu A, Zankov DP, Sato A, Kurita S, Ito M, Maeda T, Yoshida T, Sakaue T, Higashiyama S, Kawauchi A, Ogita H.
    • Journal Title

      Oncogene

      Volume: 37 Pages: 5416-5434

    • DOI

      10.1038/s41388-018-0286-0

    • Peer Reviewed / Open Access
  • [Journal Article] Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.2018

    • Author(s)
      Toshiyama, R., Konno, M., Eguchi, H., Takemoto, H., Noda, T., Asai, A., Koseki, J., Haraguchi, N., Ueda, Y. Matsushita, K., Asukai, K., Ohashi, T., Iwagami, Y., Yamada, D., Sakai, D., Asaoka, T., Kudo, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Satoh, T., Doki, Y., Nishiyama, N., Mori, M.
    • Journal Title

      Oncogene

      Volume: 38 Issue: 2 Pages: 244-260

    • DOI

      10.1038/s41388-018-0406-x

    • Peer Reviewed / Open Access
  • [Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22018

    • Author(s)
      Tatsunori Nishimura, Asuka Nakata, Xiaoxi Chen, Kurumi Nishi, Makiko Meguro-Horike, Soichiro Sasaki, Kenji Kita, Shin-ichi Horike, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Takahiko Murayama, Susumu Kohno, Chiaki Takahashi, Naofumi Mukaida, Seiji Yano, Tomoyoshi Soga, Arinobu Tojo, Noriko Gotoh
    • Journal Title

      Oncogene

      Volume: 38 Issue: 14 Pages: 2464-2481

    • DOI

      10.1038/s41388-018-0589-1

    • Peer Reviewed / Open Access
  • [Journal Article] Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells.2018

    • Author(s)
      Tamari, K., Konno, M., Asai, A., Koseki., Jun., Hayashi, K., Kawamoto, K., Murai, N., Matsufuji, S., Isohashi, F., Satoh, T., Goto, N., Tanaka, S., Doki, Y., Mori, M., Ogawa, K., Ishii, H.
    • Journal Title

      Cell Death Discovery

      Volume: 4 Issue: 104

    • DOI

      10.1038/s41420-018-0117-7

    • Peer Reviewed / Open Access
  • [Journal Article] In vivo reprogramming drives Kras-induced cancer development2018

    • Author(s)
      Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto, Yasuhiro Yamada
    • Journal Title

      Nature Communications

      Volume: 9 Pages: 2081

    • DOI

      10.1038/s41467-018-04449-5

    • Peer Reviewed / Open Access
  • [Journal Article] Reward probability and timing uncertainty alter the effect of dorsal raphe serotonin neurons on patience.2018

    • Author(s)
      Miyazaki K, Miyazaki KW, Yamanaka A, Tokuda T, Tanaka KF, Doya K.
    • Journal Title

      Nat Commun

      Volume: 9 Pages: 2048

    • DOI

      10.1038/s41467-018-04496-y

    • Peer Reviewed / Open Access
  • [Journal Article] Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis2018

    • Author(s)
      Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, Yonezawa T, Fujino T, Hayashi Y, Kawabata KC, Fukuyama T, Tanaka Y, Yokoyama A, Yamazaki S, Kozuka-Hata H, Oyama M, Kojima S. Kawazu M, Mano H. Kitamura T.
    • Journal Title

      Nature Commun.

      Volume: 9 Issue: 1 Pages: 2733

    • DOI

      10.1038/s41467-018-05085-9

    • Peer Reviewed / Open Access
  • [Journal Article] SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix2018

    • Author(s)
      Fukuda M, Yoshizawa T, et al.
    • Journal Title

      Nat Commun

      Volume: 19 Pages: 2833

    • DOI

      10.1038/s41467-018-05187-4

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] UBL3 modification influences protein sorting to small extracellular vesicles.2018

    • Author(s)
      Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.
    • Journal Title

      Nature Communications

      Volume: 9 Pages: 3936

    • DOI

      10.1038/s41467-018-06197-y

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase l.2018

    • Author(s)
      Kato K, Nishimasu H, Oikawa D, Hirano S, Hirano H, Ishitani R, Tokunaga F, Kasuya G, Nureki O.
    • Journal Title

      Nat Commun.

      Volume: 9 Pages: 4424

    • DOI

      10.1038/s41467-018-06922-7

    • Peer Reviewed / Open Access
  • [Journal Article] Neuronal sirtl regulates macronutrient-based diet selection through fgf21 and oxytocin signalling in mice.2018

    • Author(s)
      Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O. Suga T. Kobayashi M. Yamanaka A, Harada A, Nakagawa T. Onaka T, Kitamura T.
    • Journal Title

      Nat Commun

      Volume: 9 Issue: 1 Pages: 4604

    • DOI

      10.1038/s41467-018-07033-z

    • Peer Reviewed / Open Access
  • [Journal Article] Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.2018

    • Author(s)
      Sato, R., A. Kato, T. Chimura, S. I. Saitoh, T. Shibata, Y. Murakami, R. Fukui, K. Liu, Y. Zhang, J. Arii, G. H. Sun-Wada. Y. Wada, T. Ikenoue, G. N. Barber, T. Manabe, Y. Kawaguchi, and K. Miyake.
    • Journal Title

      Nat Immunol

      Volume: 19 Issue: 10 Pages: 1071-1082

    • DOI

      10.1038/s41590-018-0203-2

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Genome-vide distribution of linker histone H1.0 is independent of MeCP22018

    • Author(s)
      Ito-Ishida A, Yamalanchili HK, Shao Y, Baker SA, Heckman LD, Lavery LA, Kim JY, Lombardi LM, Sun Y, Liu Z, zoghbi HY.
    • Journal Title

      Nature Neuroscience

      Volume: 21 Issue: 6 Pages: 794-798

    • DOI

      10.1038/s41593-018-0155-8

    • Peer Reviewed / Open Access
  • [Journal Article] Sirtuin 7 deficiency ameliorates cisplatin-induced acute kidney injury through regulation of the inflammatory response.2018

    • Author(s)
      Miyasato Y, Yoshizawa T, et al.
    • Journal Title

      Sci. Rep

      Volume: 8 Pages: 5927

    • DOI

      10.1038/s41598-018-24257-7

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Improvement of cerebellar ataxic gait by injecting Cblnl into the cerebellum of cblnl-null mice2018

    • Author(s)
      Takeuchi E, Ito-Ishida A, Yuzaki M, Yanagihara D.
    • Journal Title

      Sci. Rep.

      Volume: 8 Issue: 1 Pages: 6184

    • DOI

      10.1038/s41598-018-24490-0

    • Peer Reviewed / Open Access
  • [Journal Article] Effect of Thrombin-Induced MCP-1 and MMP-3 Production Via PAR1 Expression in Murine Intervertebral Discs.2018

    • Author(s)
      Takayama Y, Ando T, Ichikawa J, Haro H
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 11320

    • DOI

      10.1038/s41598-018-29669-z

    • Peer Reviewed / Open Access
  • [Journal Article] Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model.2018

    • Author(s)
      Aoto Y, Okumura K, Hachiya T, Hase S, Wakabayashi Y, Ishikawa F, Sakakibara Y.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 12994

    • DOI

      10.1038/s41598-018-31349-x

    • Peer Reviewed / Open Access
  • [Journal Article] An extracellular [NiFe] hydrogenase mediating iron corrosion is encoded in a genetically unstable genomic island in Methanococcus maripaludis.2018

    • Author(s)
      Tsurumaru, H., Ito. N., Mori, K., Wakai. S., Uchiyama, T., Iino, T., Hosoyama, A., Ataku, H., Nishijima, K., Mise, M., Shimizu, A., Harada, T., Horikawa, H., Ichikawa, N., Sekigawa, T., Jinno, K., Tanikawa, S., Yamazaki, J., Sasaki, K., Yamazaki, S., Fujita, N., and Harayama, S.,
    • Journal Title

      Scientific Reports 8

      Volume: 8 Pages: 15149

    • DOI

      10.1038/s41598-018-33541-5

    • Peer Reviewed / Open Access
  • [Journal Article] ASXLl and SETBPI mutations promote leukaemogenesis by repressing TGFb pathway genes through histone deacetylation2018

    • Author(s)
      Saika M, Inoue D, Nagase R, Sato N, Tsuchiya A, Yabushita T, Kitamura T, Goyama S.
    • Journal Title

      Sci. Rep.

      Volume: 8 Issue: 1 Pages: 15873

    • DOI

      10.1038/s41598-018-33881-2

    • Peer Reviewed / Open Access
  • [Journal Article] Recommendation of long-term and systemic management according to the risk factors in rectal NETs patients.2018

    • Author(s)
      Motohiro Kojima, Yu Chen, Koji Ikeda, Yuichiro Tsukada, Daigoro Takahashi, Shingo Kawano, Kota Amemiya, Masaaki Ito, Rieko Ohki, Atsushi Ochiai.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 2404

    • DOI

      10.1038/s41598-018-37707-z

    • Peer Reviewed / Open Access
  • [Journal Article] Development of G-quadruplex ligand for selective induction of parallel-type topology2018

    • Author(s)
      Yue Ma, Yamato Tsushima, Mai Sakuma, Shogo Sasaki, Keisuke Iida, Sachiko Okabe, Hiroyuki Seimiya, Takatsugu Hirokawa, Kazuo Nagasawa
    • Journal Title

      Org. Biomol. Chem.

      Volume: 16 Pages: 7375-7382

    • DOI

      10.1038/C8OB01702F

    • Peer Reviewed
  • [Journal Article] Design of C2-symmetric alkaloidal chiral amphiphiles and configurational effects on self-assembly2018

    • Author(s)
      Nana Tsuchiya, Yunosuke Ryu, Takahiro Muraoka, Hiroki Oguri
    • Journal Title

      Org. Biomol. Chem.

      Volume: 16 Pages: 9305-9313

    • DOI

      10.1039/C8OB02287A

    • Peer Reviewed
  • [Journal Article] Interaction between cardiac myosin-binding protein C and formin Fhod3.2018

    • Author(s)
      Natsuyama S, Kage Y. Fujimoto N, Ushijima T, Tsuruda T, Kitamura K, Shiose A, Asada Y, Sumimoto H, Takeya R.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 115 Issue: 19 Pages: E4386-E4395

    • DOI

      10.1073/pnas.1716498115

    • Peer Reviewed
  • [Journal Article] Transcripts from downstream alternative transcription start sites evade uORF-mediated inhibition of gene expression in Arabidopsis.2018

    • Author(s)
      Kurihara Y. Makita Y. Kawashima M. Fujita T. Iwasaki S. and Matsui M.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 115 Issue: 30 Pages: 7831-7836

    • DOI

      10.1073/pnas.1804971115

    • Peer Reviewed
  • [Journal Article] Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.2018

    • Author(s)
      Tominaga, K., Ninato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K., Tojo, A., Gotoh, N.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 116 Issue: 2 Pages: 625-630

    • DOI

      10.1073/pnas.1806851116.Epub2018Dec26

    • Peer Reviewed / Open Access
  • [Journal Article] Anabolic-androgenic steroids : procurement and administration practices of doping athletes.2018

    • Author(s)
      Fink J, Jackney A, Matsumoto M, Maekawa T, Nakazato K, Horie S.
    • Journal Title

      Physician, Sportsmedicine 2

      Volume: 47 Issue: 1 Pages: 10-14

    • DOI

      10.1080/00913847.2018.1526626

    • Peer Reviewed / Open Access
  • [Journal Article] Generation of rat monoclonal antibodies specific for DZIP32018

    • Author(s)
      Oikawa D, Shiota M, Tokunaga F, Wanibuchi H.
    • Journal Title

      Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

      Volume: 37 Issue: 3 Pages: 153-157

    • DOI

      10.1089/mab.2018.0005

    • Peer Reviewed
  • [Journal Article] Generation of rat monoclonal antibodies against a deubiquitinase, ovarian tumor domain-containing protein 12018

    • Author(s)
      Oikawa D, Shiota M, Wanibuchi H. Tokunaga F.
    • Journal Title

      Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

      Volume: 37 Issue: 4 Pages: 180-184

    • DOI

      10.1089/mab.2018.0023

    • Peer Reviewed
  • [Journal Article] A highly sensitive trap vector system for isolating reporter cells and identification of responsive genes2018

    • Author(s)
      Kosuke Ishikawa, Yuta Kobayashi, Yutaro wakabayashi, Shinya Watanabe and Kentaro Semba
    • Journal Title

      Biology Methods and Protocols

      Volume: 3 Pages: bpy003

    • DOI

      10.1093/biomethods/bpy003

    • Peer Reviewed / Open Access
  • [Journal Article] Biallelic UFMI and UFCI mutations expand the essential role of ufmylation in brain development.2018

    • Author(s)
      Michael S Nahorski, Sateesh Maddirevula, Ryosuke Ishimura, Saud Alsahli, Angela Brady, Anaïs Begemann, Tsunehiro Mizushima, Francisco J. Guzmán-Vega, Miki Obata, Yoshinobu Ichimura, Hessa S Alsaif, Shams Anazi, Niema Ibrahim, Firdous Abdulwahab, Mais Hashem, Dorota Monies, Mohamed Abouelhoda, Brian F Meyer, Majid Alfadhel, Wafa Eyaid, Markus Zweier Katharina Steindl, Anita Rauch, Stefan T. Arold, *C Geoffrey Woods, Masaaki Komatsu, Fowzan S Alkuraya
    • Journal Title

      Brain

      Volume: 141 Pages: 1934-1945

    • DOI

      10.1093/brain/awy135

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.2018

    • Author(s)
      Nakanishi K, Niida H, Tabata H, Ito T, Hori Y, Hattori M, Johmura Y, Yamada C, Ueda T, Takeuchi K, Yamada K, Nagata KI, Wakamatsu N, Kishi M, Pan YA, Ugawa S, Shimada S, Sanes JR, Higashi Y, Nakanishi M.
    • Journal Title

      Cerebral Cortex

    • DOI

      10.1093/cercor/bhy253

    • Peer Reviewed
  • [Journal Article] BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of variants in chromatin remodeling genes2018

    • Author(s)
      Hisashi Hasumi, Mitsuko Furuya, Kenji Tatsuno, Shogo Yamamoto, Masaya Baba, Yukiko Hasumi, Yasuhiro Isono, Kae Suzuki, Ryosuke Jikuya, Shinji Otake, Kentaro Muraoka, Kimito Osaka, Narihiko Hayashi, Kazuhide Makiyama, Yasuhide Miyoshi, Keiichi Kondo, Noboru Nakaigawa, Takashi Kawahara, Koji Izumi, Junichi Teranishi, Yasushi Yumura, Hiroji Uemura, Yoji Nagashima, Adam R Metwalli, Laura S Schmidt,
    • Journal Title

      Human molecular genetics

      Volume: 27 Issue: 15 Pages: 2712-2724

    • DOI

      10.1093/hmg/ddy181

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Partial ablation of the orexin field induces a sub-narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration.2018

    • Author(s)
      Black SW, Sun JD, Santiago P, Laihsu A, Kimura N, Yamanaka A, Bersot R, Humphries PS
    • Journal Title

      Sleep

      Volume: 41 Issue: 9

    • DOI

      10.1093/sleep/zsy116

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Generalized verrucosis caused by various human papillomaviruses in a patient with GATA2 deficiency2018

    • Author(s)
      Kuriyama Y, Hattori M, Mitsui T, Nakano H, Oikawa D, Tokunaga F, Ishikawa O, Shimizu A.
    • Journal Title

      Journal of Dermatology

      Volume: 45 Issue: 5 Pages: e108-e109

    • DOI

      10.1111/1346-8138

    • Peer Reviewed
  • [Journal Article] The orphan nuclear receptor NR4A1 promotes FcepsilonRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis.2018

    • Author(s)
      Jin F, Li X. Deng Y, Timilshina M. Huang B, Kim DY, Chang JH, Ichinose H, Baek SH, Murakami M, Lee YJ, Chang HW
    • Journal Title

      Allergy

    • DOI

      10.1111/all.13702

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Study on the tumor-induced angiogenesis using mathematical models.2018

    • Author(s)
      Suzuki T, Minerva D, Nishiyama K, Koshikawa N, Chaplain MAJ.
    • Journal Title

      Cancer Science

      Volume: 109 Pages: 15-23

    • DOI

      10.1111/cas.13395

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Spontaneous development of intratumoral heterogeneity in a transposon-induced mouse model of glioma2018

    • Author(s)
      Sumiyoshi K, Koso H, Watanabe S.
    • Journal Title

      Cancer Sci.

      Volume: 109 Issue: 5 Pages: 1513-1523

    • DOI

      10.1111/cas.13579

    • Peer Reviewed / Open Access
  • [Journal Article] Expression of cytosolic malic enzyme (ME1) is associated with disease progression in human oral squamous cell carcinoma.2018

    • Author(s)
      Nakashima C, Yamamoto K, Fujiwara-Tani R, Luo Y, Matsushima S, Fujii K, Ohmori H, Sasahira T, Sasaki T, Kitadai Y, Kirita T, Kuniyasu H
    • Journal Title

      Cancer Sci

      Volume: 109 Issue: 6 Pages: 2036-2045

    • DOI

      10.1111/cas.13594

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.2018

    • Author(s)
      Vu HT, Kobayashi M, Hegazy AM, Tadokoro Y, Ueno M, Kasahara A, Takase Y, Nomura N, Peng H, Ito C, Ino Y, Todo T, Nakada M, Hirao A.
    • Journal Title

      Cancer Sci

      Volume: 109 Pages: 2497-2508

    • DOI

      10.1111/cas.13695

    • Peer Reviewed / Open Access
  • [Journal Article] PHLDAI, another PHLDA family protein that inhibits AKt.2018

    • Author(s)
      Yu Chen, Masahiro Takikawa, Shuichi Tsutsumi, Yoko Yamaguchi, Atsushi Okabe, Mayuna Shibata, Tatsuya Kawase, Akane Sada, Issei Ezawa, Yuhei Takano, Kisaburo Nagata, Yutaka Suzuki, Kentaro Semba, Hiroyuki Aburatani, Rieko Ohki.
    • Journal Title

      Cancer Science

      Volume: 109 Pages: 3532-3542

    • DOI

      10.1111/cas.13796

    • Peer Reviewed / Open Access
  • [Journal Article] RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.2018

    • Author(s)
      Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 12 Pages: 4003-4014

    • DOI

      10.1111/cas.13805

    • Peer Reviewed / Open Access
  • [Journal Article] Physiological and pathological relevance of cell competition in fly to mammals.2018

    • Author(s)
      Shunsuke Kon.
    • Journal Title

      Development, Growth and Differentiation

      Volume: 60 Pages: 14-20

    • DOI

      10.1111/dgd.12415

    • Peer Reviewed / Open Access
  • [Journal Article] Transdifferentiation of human somatic cells by ribosome.2018

    • Author(s)
      Ito N., Mohammad B., A., Shah A., I., A., and Ohta K.
    • Journal Title

      Development Growth & Differentiation

      Volume: 60 Pages: 241-247

    • DOI

      10.1111/dgd.12538

    • Peer Reviewed
  • [Journal Article] Identification and functional analysis of inflammation-related miRNAs in skin wound repair.2018

    • Author(s)
      Mori R, Tanaka K, Shimokawa Ⅰ
    • Journal Title

      Dev Growth Differ

      Volume: 60 Issue: 6 Pages: 306-315

    • DOI

      10.1111/dgd.12542

    • Peer Reviewed / Open Access
  • [Journal Article] Pancreatic adenocarcinoma upregulated factor has oncogenic functions in oral squamous cell carcinoma.2018

    • Author(s)
      Sasahira T, Kurihara M, Nishiguchi Y, Nakashima C, Kirita T, Kuniyasu H
    • Journal Title

      Histopathol

      Volume: 70 Issue: 4 Pages: 539-548

    • DOI

      10.1111/his.13097

    • Peer Reviewed
  • [Journal Article] Ectopic positioning of Bergmann glia and impaired cerebellar wiring in Mlcl-over-expressing mice.2018

    • Author(s)
      Kikuchibara S, Sugio S, Tanaka KF, Watanabe T, Kano M, Yamazaki Y, Watanabe M, Ikenaka K.
    • Journal Title

      J Neurochem

      Volume: 147 Issue: 3 Pages: 344-360

    • DOI

      10.1111/jnc.14486

    • Peer Reviewed
  • [Journal Article] Deletion of exons encoding carboxypeptidase domain of Nnal results in Purkinje cell degeneration (pcd) phenotype.2018

    • Author(s)
      Zhou L, Hossain MI, Yamazaki M, Abe M, Natsume R, Konno K, Kageyama S, Komatsu M, Watanabe M, Sakimura K, Takebayashi H.
    • Journal Title

      J Neurochem.

      Volume: 147 Pages: 557-572

    • DOI

      10.1111/jnc.14591

    • Peer Reviewed
  • [Journal Article] Functional characterization of recombinant snake venom rhodocytin : rhodocytin mutant blocks CLEC-2/podoplanin-dependent platelet aggregation and lung metastasis.2018

    • Author(s)
      Sasaki T, Shirai T, Tsukiji N, Otake S, Tamura S, Ichikawa J, Osada M, Satoh K, Ozaki Y, Suzuki-Inoue K.
    • Journal Title

      J Thromb Haemost

      Volume: 16 Issue: 5 Pages: 960-972

    • DOI

      10.1111/jth.13987

    • Peer Reviewed
  • [Journal Article] Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy.2018

    • Author(s)
      Thannickal TC, John J, Shan L, Swaab DF, Wu MF, Ramanathan L, McGregor R, Chew KT, Cornford M, Yamanaka A, Inutsuka A, Fronczek R, Lammers GJ, Worley PF, Siegel JM.
    • Journal Title

      Sci Transl Med

      Volume: 10 Pages: 447

    • DOI

      10.1126/scitranslmed.aao4953

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Multisensory enhancement of burst activity in an insect auditory neuron2018

    • Author(s)
      Someya, M, and Ogawa, H.
    • Journal Title

      J Neurophysiol.

      Volume: 120 Pages: 139-148.

    • DOI

      10.1152/jn.00798.2017

    • Peer Reviewed
  • [Journal Article] Ability of a convolutional neural network to differentiate between mouse and human cell lines and their radioresistant clones using microscopic images.2018

    • Author(s)
      Toratani, M., Konno, M., Asai. A., Koseki, J., Kawamoto, K., Tamari, K., Li, Z., Sakai, D., Kudo, T., Satoh, T., Sato, K., Motooka, D., Okuzaki, D., Doki, Y., Mori, M., Ogawa, K., Ishii, H.
    • Journal Title

      Cancer Res

      Volume: 78

    • DOI

      10.1158/0008-5472

    • Peer Reviewed / Open Access
  • [Journal Article] p63-dependent Dickkopf3 expression promotes esophageal cancer cell proliferation via CKAP42018

    • Author(s)
      Kajiwara C, Fumoto K, Kimura H, Nojima S, Asano K, Odagiri K, Yamasaki M, Hikita H, Takehara T, Doki Y, Morii E, Kikuchi A.
    • Journal Title

      Cancer Res.

      Volume: 78 Pages: 3471-3484

    • DOI

      10.1158/0008-5472.CAN-18-1749

    • Peer Reviewed
  • [Journal Article] Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis.2018

    • Author(s)
      Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T*, Sato K
    • Journal Title

      Mol Cancer Res

      Volume: 16 Issue: 3 Pages: 554-563

    • DOI

      10.1158/1541-7786.MCR-17-0393

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Pathobiologic Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.2018

    • Author(s)
      Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger G, Wang J, Dong Y, Zhou Y, Wang J, Wu LY, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, et al.
    • Journal Title

      Cancer Discovery

      Volume: 8 Issue: 11 Pages: 1438-57

    • DOI

      10.1158/2159-8290.CD-17-1203

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018

    • Author(s)
      Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M.
    • Journal Title

      Jounal of Clinical Investigation

      Volume: 128 Issue: 12 Pages: 5603-5619

    • DOI

      10.1172/JCI121679

    • Peer Reviewed
  • [Journal Article] Ezh2 loss propagates hypermethylation at T-cell differentiation-regulating genes to promote leukemic transformation.2018

    • Author(s)
      Wang C, Oshima M, Sato D, Matsui H, Kubota S, Aoyama K, Nakajima-Takagi Y, Koide S, Matsubayashi J, Mochizuki-Kashio M, Nakano-Yokomizo T, Bai J, Nagao T, Kanai A, Iwama A, Sashida G.
    • Journal Title

      J Clin Invest

      Volume: 128 Issue: 9 Pages: 3872-86

    • DOI

      10.1172/JCI94645

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Predominant synaptic potentiation and activation of the right central amygdala are independent of bilateral paracrachial activation in the hemilateral trigeminal inflammatory pain model of rats2018

    • Author(s)
      Miyazawa, Y., Takahashi, Y., Watabe, A. M. and Kato F.
    • Journal Title

      Molecular Pain

      Volume: 14 Pages: 1744806918807100

    • DOI

      10.1177/1744806918807102

    • Peer Reviewed / Open Access
  • [Journal Article] High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System2018

    • Author(s)
      Katsuya K, Hori Y, Oikawa D, Yamamoto T, Umetani K, Urashima T, Kinoshita T, Ayukawa K, Tokunaga F, Tamaru M.
    • Journal Title

      SLAS Discovery

      Volume: 23 Issue: 10 Pages: 1018-1029

    • DOI

      10.1177/2472555218793066

    • Peer Reviewed
  • [Journal Article] Splice-site mutation causing partial retention of intron in the FLCN gene in Birt-Hogg-Dubé syndrome : a case report2018

    • Author(s)
      Mitsuko Furuya, Hironori Kobayashi, Masaya Baba, Takaaki Ito, Reiko Tanaka, Yukio Nakatani
    • Journal Title

      BMC medical genomics

      Volume: 11

    • DOI

      10.1186/s12920-018-0359-5

    • Peer Reviewed / Open Access
  • [Journal Article] Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation.2018

    • Author(s)
      Ng IK, Lee J, Ng C, Kosmo B, Chiu L, Seah E, Mok MMH, Tan K, Osato M, Chng WJ, Yan B, Tan LK.
    • Journal Title

      Biomark Res.

      Volume: 6 Pages: 16

    • DOI

      10.1186/s40364-018-0130-2

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Glucagonoma With Necrolytic Migratory Erythema : Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene.2018

    • Author(s)
      Tamura A, Ogasawara T, Fujii Y, Kaneko H, Nakayama A, Higuchi S, Hashimoto N, Niyabayashi Y, Fujimoto M, Komai E, Kono T, Sakuma I, Nagano H, Suzuki S, Koide H, Yokote K, Iseki K, Oguma R, Matsue H, Nojima H, Sugiura K, Yoshitomi H, Ohtsuka M, Rahmutulla B, Kaneda A, Inoshita N, Ogawa S, Tanaka T.
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 103 Issue: 7 Pages: 2417-2423

    • DOI

      10.1210/jc.2017-02646

    • Peer Reviewed / Open Access
  • [Journal Article] p62/SQSTM1-steering the cell through health and disease.2018

    • Author(s)
      Sánchez-Martin P, Komatsu M.
    • Journal Title

      J Cell Sci.

      Volume: 131

    • DOI

      10.1242/jcs.222836

    • Peer Reviewed / Open Access
  • [Journal Article] The autism-related protein CHD8 cooperates with C/EBPβ to regulate adipogenesis.2018

    • Author(s)
      Matsumoto A., Nakayama KI.
    • Journal Title

      Cell Struct. Funct.

      Volume: 43 Pages: 75-83

    • DOI

      10.1247/csf.18005

    • Peer Reviewed / Open Access
  • [Journal Article] An Anti-tumorigenic Role of the Warburg Effect at Emergence of Transformed Cells.2018

    • Author(s)
      Kojiro Ishibashi, Riku Egami, Kazuki Nakai, Shunsuke Kon
    • Journal Title

      Cell Structure and Function

      Volume: 43 Pages: 171-176

    • DOI

      10.1247/csf.18018

    • Peer Reviewed / Open Access
  • [Journal Article] i-Motif-binding ligand and their effects on the structure and biological functions of i-motif2018

    • Author(s)
      Shadi Sedghi Masoud, Kazuo Nagasawa
    • Journal Title

      Chem. Pharm. Bull.

      Volume: 66 Pages: 1091-1103

    • DOI

      10.1248/cpb.c18-00720

    • Peer Reviewed / Open Access
  • [Journal Article] UPA-Seq : Prediction of Functional LncRNAs Using Differential Sensitivity to UV Crosslinking.2018

    • Author(s)
      Taiwa K, Yokoi S, Mito M2, Fujii K, Kimura Y, Iwasaki S, Nakagawa S.
    • Journal Title

      RNA

      Volume: 24 Issue: 12 Pages: 1785-1802.

    • DOI

      10.1261/rna.067611.118

    • Peer Reviewed
  • [Journal Article] Freezing sperm in short straws reduces storage space and allows transport in dry ice.2018

    • Author(s)
      Kaneko R, Kakinuma T, Sato S, Jinno-Oue A.
    • Journal Title

      J Reprod Dev.

      Volume: 64 Issue: 6 Pages: 541-545

    • DOI

      10.1262/jrd.2018-100

    • Peer Reviewed / Open Access
  • [Journal Article] Fracture risk assessment tool (FRAX) and for the diagnosis of osteoporosis in Japanese middle-aged and elderly women : Chiba bone survey.2018

    • Author(s)
      Oka R, Ohira M, Suzuki S, Yoshida T, Koide H, Tanaka T, Tatsuno I.
    • Journal Title

      Endocr J

      Volume: 65 Issue: 2 Pages: 193-202

    • DOI

      10.1507/endocrj.EJ17-0331

    • Peer Reviewed / Open Access
  • [Journal Article] Deficiency of AMPA receptor-palmitoylation aggravates seizure susceptibility.2018

    • Author(s)
      Itoh M, Yamashita M, Kaneko M, Okuno H, Abe M, Yamazaki M, Natsume R, Yamada D, Kaizuka T. Suwa R, Sakimura K, Sekiguchi M, Wada K, Hoshino M, Mishina M, Hayashi T
    • Journal Title

      Journal of Neuroscience

      Volume: 38 Pages: 10220-10235

    • DOI

      10.1523/JNEUROSCI.1590-18.2018

    • Peer Reviewed
  • [Journal Article] New observations in neuroscience using superresolution microscopy2018

    • Author(s)
      *Igarashi M, Nozumi M, Wu LG, Cella Zanacchi F, Katona I, Barna L, Xu P, Zhang M, Xue F. Boyden E
    • Journal Title

      J Neurosci

      Volume: 38 Pages: 9459-9467

    • DOI

      10.1523/JNEUROSCI.1678-18.2018

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds.2018

    • Author(s)
      de Kerckhove M, Tanaka K, Umehara T, Okamoto M, Kanematsu S, Hayashi H, Yano H, Nishiura S, Tooyama S, Matsubayashi Y, Komatsu To. Park S, Okada Y, Takahashi R, Kawano Y, Hanawa T, Iwasaki K, Nozaki T, Torigoe H, Ikematsu K, Suzuki Y, Tanaka K, Martin P, Shimokawa I, Mori R
    • Journal Title

      EMBO Mol Med

      Volume: 10 Issue: 10 Pages: e9024

    • DOI

      10.15252/emmm.201809024

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The role of PTH in mouse skin tumorigenesis.2018

    • Author(s)
      Okumura K, Saito M, and Wakabayashi Y.
    • Journal Title

      Integrative Cancer Science and Therapeutics

      Volume: 5 Pages: 2

    • DOI

      10.15761/ICST.1000271

    • Peer Reviewed / Open Access
  • [Journal Article] Regulatory role of resveratrol, a microRNA-controlling compound, in HNRNPA1 expression, which is associated with poor prognosis in breast cancer2018

    • Author(s)
      Kurataka Otsuka, Yusuke Yamamoto, Takahiro Ochiya
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 37 Pages: 24718-24730

    • DOI

      10.18632/oncotarget.25339

    • Peer Reviewed / Open Access
  • [Journal Article] Anti-claudin-4 extracellular domain antibody enhances the antitumoral effects of chemotherapeutic and antibody drugs in colorectal cancer2018

    • Author(s)
      Fujiwara-Tani R, Sasaki T, Luo Y, Ohmori H, Nishiguchi Y, Kishi S, Mori S, Goto K, Kondoh M, Kuniyasu H
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 100 Pages: 37367-37378

    • DOI

      10.18632/oncotarget.26427

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comparison of brain monoamine content in three populations of Lymnaea that correlates with taste-aversive learning ability2018

    • Author(s)
      Aonuma H., Totani Y., Sakakibara M., Lukowiak K. and Ito E.
    • Journal Title

      Biophys. Physicobiol.

      Volume: 15 Pages: 129-135

    • DOI

      10.2142/biophysico.15.0_129

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Prednisolone-responsive Postpartum IgG4-related Hypophysitis.2018

    • Author(s)
      Koide H, Shiga A, Komai E, Yamato A, Fujimoto M, Tamura A, Kono T, Nakayama A, Takiguchi T, Higuchi S, Sakuma I, Nagano H, Hashimoto N, Suzuki S, Takeda Y, Shibuya M, Nishioka H, Yamada S, Inoshita N, Ishiwatari N, Horiguchi K, Yokote K, Tanaka T.
    • Journal Title

      Intern Med

      Volume: 57 Issue: 3 Pages: 367-375

    • DOI

      10.2169/internalmedicine

    • Peer Reviewed / Open Access
  • [Journal Article] Activated EphA2 processing by MT1-MMP is involved in malignant transformation of ovarian tumours in vivo2018

    • Author(s)
      Takahashi Y, Hamasaki M, Aoki M, Koga K, Koshikawa N, Miyamoto S, Nabeshima K.
    • Journal Title

      Anticancer Res

      Volume: 38 Pages: 4257-4266

    • DOI

      10.21873/anticanres.12722

    • Peer Reviewed
  • [Journal Article] Cleavage of Toll-Like Receptor 9 Ectodomain Is Required for In Vivo Responses to Single Strand DNA.2018

    • Author(s)
      Fukui, R., C. Yamamoto, F. Matsumoto, M. Onji, T. Shibata, Y. Murakami, A. Kanno, T. Hayashi, N. Tanimura, N. Yoshida, and K. Miyake.
    • Journal Title

      Front Immunol

      Volume: 9 Pages: 1491

    • DOI

      10.3389/fimmu.2018.01491

    • Peer Reviewed / Open Access
  • [Journal Article] Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function.2018

    • Author(s)
      Tel-Karthaus N, Kers-Rebel ED, Looman MW, Ichinose H, de Vries CJ, Ansems M
    • Journal Title

      Front Immunol

      Volume: 9 Pages: 1797

    • DOI

      10.3389/fimmu.2018.01797

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Organelle Optogenetics : Direct Manipulation of Intercellular Ca2+ Dynamics by Light.2018

    • Author(s)
      Asano T, Igarashi H, Ishizuka T, Yawo H
    • Journal Title

      Front Neurosci.

      Volume: 12 Pages: 561

    • DOI

      10.3389/fnins.2018.00561

    • Peer Reviewed / Open Access
  • [Journal Article] Activation of p62/SQSTM1-Keap1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Cancer.2018

    • Author(s)
      Ichimura Y, Komatsu M.
    • Journal Title

      Front Oncol.

      Volume: 8

    • DOI

      10.3389/fonce.2018.00210

    • Peer Reviewed / Open Access
  • [Journal Article] Inactivation of serotonergic neurons in the rostral medullary raphe attenuates stress-induced tachypnea and tachycardia in mice.2018

    • Author(s)
      Ikoma Y, Kusumoto-Yoshida I, Yamanaka A, Ootsuka Y, Kuwaki T.
    • Journal Title

      Front Physiol

      Volume: 9 Pages: 832

    • DOI

      10.3389/fphys.2018.00832

    • Peer Reviewed
  • [Journal Article] SK-216, a novel inhibitor of plasminogen activator inhibitor-1, suppresses lung metastasis of human osteosarcoma2018

    • Author(s)
      Tsuge M, Osaki M, Sasaki R, Hirahata M, Okada F
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 3 Pages: 736

    • DOI

      10.3390/ijms19030736

    • Peer Reviewed / Open Access
  • [Journal Article] Vascular endothelial growth factor-A exerts diverse cellular effects via small G proteins, Rho and Rap.2018

    • Author(s)
      Shimizu A, Zankov DP, Kurokawa-Seo M, Ogita H.
    • Journal Title

      Int J Mo2 Sci

      Volume: 19 Pages: E1203

    • DOI

      10.3390/ijms19041203

    • Peer Reviewed / Open Access
  • [Journal Article] Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment.2018

    • Author(s)
      Morinaga T, Yamaguchi N, Nakayama Y, Tagawa M, Yamaguchi N
    • Journal Title

      Int J Mo1 Sci.

      Volume: 19 Issue: 6 Pages: E1811

    • DOI

      10.3390/ijms19061811

    • Peer Reviewed / Open Access
  • [Journal Article] The multifarious functions of pyruvate kinase M2 in oral cancer cells.2018

    • Author(s)
      Kurihara-Shimomura M, Sasahira T, Nakashima C, Kuniyasu H, Shimomura H, Kirita T.
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 10 Pages: E2907

    • DOI

      10.3390/ijms19102907

    • Peer Reviewed / Open Access
  • [Journal Article] Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy.2018

    • Author(s)
      Shimizu Y, Tamada S, Kato M, Hirayama Y, Takeyama Y, Iguchi T, Sadar MD, Nakatani T.
    • Journal Title

      J Clin Med

      Volume: 7 Issue: 11 Pages: E444

    • DOI

      10.3390/jcm7110444

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer2018

    • Author(s)
      Noguchi K, Konno M, Eguchi H, Kawamoto K, Mukai R, Nishida N, Koseki J, Wada H, Akita H, Satoh T, Marubashi S, Nagano H, Doki Y, Mori M, Ishii H.
    • Journal Title

      Oncol Lett

      Volume: 16 Issue: 2 Pages: 1892-1898

    • DOI

      10.3892/ol.2018.8793

    • Peer Reviewed
  • [Journal Article] Intake of medium-chain fatty acids induces oxidative stress and to atrophy the myocardium2018

    • Author(s)
      Miyagawa Y, Mori T, Goto K, Fujiwara-Tani R, Kishi S, Sasaki T, Fujii K, Ohmori H, Kawahara I, Kuniyasu H
    • Journal Title

      Lipids in Health and Disease

      Volume: 17 Pages: 258

    • DOI

      10.1186/s12944-018-0908-0

    • Peer Reviewed / Open Access
  • [Journal Article] Significance of intranuclear angiotensin-Ⅱ type 2 receptor in oral squamous cell carcinoma2018

    • Author(s)
      Natsushima-Otsuka S, Fujiwara-Tani R, Sasaki T, Ohmori H Nakashima C, Kishi S, Nishiguchi Y, Fujii K, Luo Y, Kuniyasu H
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 93 Pages: 36561-36574

    • DOI

      10.18632/oncotarget.26337

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] “サイズ”で斬る生物学への誘い2018

    • Author(s)
      山本一男
    • Journal Title

      実験医学

      Volume: 36 Issue: 13 Pages: 2168-2173

  • [Journal Article] 超低周波電磁界の神経幹細胞に及ぼす影響評価に関する研究2018

    • Author(s)
      石堂正美
    • Journal Title

      磁気と健康

      Volume: 30 Pages: 20-25

  • [Journal Article] Generation of functional oocytes of common marmoset by xeno-transplantation of ovarian tssue2018

    • Author(s)
      Shiori Miura, Yoshitaka Maeda, Jun Miyamoto, Ena Nakatsukasa, Nobuyoshi Fujisawa, Miki Miwa, Katsuki Nakamura, Kenji Sakimura and Toshikuni Sasaoka
    • Journal Title

      Proceedings of International Symposium on Animal Production and Conservation for Sustainable Development 2018

      Pages: 31-33

  • [Journal Article] Piwi Nuclear Localization and Its Regulatory Mechanism in Drosophila Ovarian Somatic Cells.2018

    • Author(s)
      Yashiro R, Murota Y, Nishida KM, Yamashiro H, Fujii K, Ogai A, Yamanaka S, Negishi L, Siomi H, Siomi MC.
    • Journal Title

      Cell Reports

      Volume: 23 Pages: 3647-3657

    • DOI

      10.1016/j.celrep.2018.05.051

    • Peer Reviewed / Open Access
  • [Journal Article] Mobility and biomechanical functions in the aging male : testosterone and the Locomotive Syndrome.2018

    • Author(s)
      Fink J, Jackney A, Matsumoto M, Maekawa T, Nkazato K, Horie S.
    • Journal Title

      Aging Male

      Volume: 29 Pages: 1-8

    • DOI

      10.1080/13685538.2018.1504914

    • Peer Reviewed
  • [Journal Article] The interplay between autophagy and tumorigenesis : exploiting autophagy as a means of anticancer therapy.2018

    • Author(s)
      Lorente J. Velandia C, Leal JA, Garcia-Mayea Y, Lyakhovich A, Kondoh H, LLeonart ME.
    • Journal Title

      Biol Rev Camb Philos Soc.

      Volume: 93 Issue: 1 Pages: 152-165

    • DOI

      10.1111/brv.12337

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Complete Sequences of the HTLV-1 Proviral Genomes from Newly Established ATL cell-lines in Oita Prefecture, Japan2018

    • Author(s)
      Takuro Fukumoto, Emi Ikebe, Masao Ogata, Kazuhiro Kohno, Madoka Kuramitsu, Yusuke Sato, Nichole Fife, Takashi Matsumoto, Takaaki Yahiro, Masanori Ikeda, Shuichi Kusano, Akihiko Okayama, Mitsuo Hori, Naoki Hijiya, Yoshiyuki Tsukamoto, Yuka Hirashita, Masatsugu Moriyama, Kamruddin Ahmed, Hiroo Hasegawa, Akira Nishizono, Masumichi Saito*, and Hidekatsu Iha*
    • Journal Title

      Genome Announcements

      Volume: 6 Issue: 25 Pages: e00090-18

    • DOI

      10.1128/genomeA.00090-18

    • Peer Reviewed / Open Access
  • [Presentation] KLF4によるプロテアーゼ発現制御機構の解析2019

    • Author(s)
      立田咲百合、金井凛、鬼頭昭吉、竹内優斗、阿部真土
    • Organizer
      第12回大阪大学医学系若手フォーラム
  • [Presentation] D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2019

    • Author(s)
      笹岡 俊邦、齊藤 奈英、知見 聡美、佐藤 朝子、大久保 直、福田 七穂、阿部 学、川村 名子、小田 佳奈子、佐藤 俊哉、藤澤 信義、山口 瞬、田井中 一貴、崎村 建司、南部 篤
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム 成果発表会
  • [Presentation] 劣性(潜性)遺伝形式で多血症の症状を示す自然発生突然変異マウス『pocy』の解析2019

    • Author(s)
      北元優梨、古閑成美、林田隆成、慶田貴子、吉信公美子、鳥越大輔、中村直子、中潟直己、高岡裕、柳久美子、要匡、荒木喜美、荒木正健
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム 成果発表会
  • [Presentation] A novel TMEM168 gene mutation in familial Brugada syndrome attenuates Na+ channel function by modulating Nav1.5 expression.2019

    • Author(s)
      Dimitar P. Zankov、扇田久和
    • Organizer
      第83回日本循環器学会学術集会
  • [Presentation] Accelerated climbing fiber synapse elimination in cerebellar Purkinje cells lacking protocadherin 102019

    • Author(s)
      渡邉貴樹, 井上秀太郎, 赤松翼, 鈴木穂香, 佐郡 和人, 阿部学, 崎村建司, 上阪直史, 狩野方伸
    • Organizer
      9th FAOPS
    • Int'l Joint Research
  • [Presentation] Activity-dependent synapse elimination in the developing cerebellum2019

    • Author(s)
      上阪直史
    • Organizer
      9th FAOPS
    • Int'l Joint Research
  • [Presentation] Adeno-associated virus vector micro injection into mice brain to reveal function of neural circuitry involved in the regulation of sleep/wakefulness.2019

    • Author(s)
      Yamanaka A
    • Organizer
      FAOPS2019
    • Int'l Joint Research / Invited
  • [Presentation] Alpha-particle-emitting astatine-211-labeled trastuzumab for targeted cancer cell ablation2019

    • Author(s)
      李 惠子、長谷川 純崇
    • Organizer
      第11回日米合同癌会議
    • Int'l Joint Research
  • [Presentation] Anticancer property and mechanisms of action of newly synthesized drugs2019

    • Author(s)
      安藤さえこ、吉本恵里、深町勝巳、松本晴年、酒々井眞澄
    • Organizer
      第35回日本毒性病理学会総会及び学術集会
  • [Presentation] Brugada syndrome-associated novel TMEM168 gene mutation attenuates Na+ channel function through Nav1.5 degradation.2019

    • Author(s)
      Dimitar P. Zankov、扇田久和
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] Cancer drug screening based on refractoriness of cancer cell reprogramming2019

    • Author(s)
      伊藤 謙治
    • Organizer
      Cellular Plasticity : Reprogramming, Regeneration and Metaplasia
    • Int'l Joint Research
  • [Presentation] Cellular diversity by genetic and non-genetic alteration in cancer induces acquired resistance in NSCLC2019

    • Author(s)
      Ryohei Katayama, Bo Gong, Koutaroh Okada, Makoto Nishio, Naoya Fujita
    • Organizer
      11th AACR-JCA Joint Conference
    • Int'l Joint Research / Invited
  • [Presentation] DYRK2欠損マウスは肺低形成により呼吸不全となり、出生直後致死となる2019

    • Author(s)
      與五沢里美、吉田清嗣
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] Elucidation of motor control mechanism using genetically modified mice harboring tetracycline regulated expression of D1/D2 dopamine receptors2019

    • Author(s)
      齊藤奈英、知見聡美、大久保朝子、阿部学、川村名子、山口瞬、崎村建司、田井中一貴、南部篤、笹岡俊邦
    • Organizer
      第8回生理研-霊長研-脳研合同シンポジウム
  • [Presentation] ITPA欠損によるヒトてんかん性脳症のモデルとしての神経幹細胞特異的Itpaノックアウトマウス2019

    • Author(s)
      土本 大介、古賀 祐一郎、林 良憲、アボルハッサニ ノナ、米嶋 康臣、中西 博、豊國 伸哉、中別府 雄作
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] Metabolic regulation by TFE3 in cell proliferation and differentiation2019

    • Author(s)
      Masaya Baba
    • Organizer
      The 2nd KU-KAIST Joint Symposium
    • Int'l Joint Research / Invited
  • [Presentation] Partially hydrolyzed guar gum improves small intestinal degeneration in association with modulation of intestinal microbiota after massive small bowel resection2019

    • Author(s)
      Takayuki Fujii, Yoichi Chiba, Haruyuki Nakayama-Imaohji, Shun Onishi, Aya Tanaka, Hiroto Katami, Masaki Ueno, Tomomi Kuwahara, Tatsuru Kaji, Satoshi Ieiri, Ryuichi Shmono
    • Organizer
      52nd annual meeting of the pacific association of pediatric surgeons
    • Int'l Joint Research
  • [Presentation] Remote memory traces in the mouse hippocampus revealed by Arc-based functional labeling2019

    • Author(s)
      Hiroyuki Okuno, Anna Araki, Keiichiro Minatohara, Haruhiko Bito, Itaru Imayoshi
    • Organizer
      アジア・オセアニア国際生理学大会(FAOPS2019)
    • Int'l Joint Research
  • [Presentation] Role of an oligosaccharide in the hemagglutinin protein on the pathogenesis of H3N2 influenza A virus2019

    • Author(s)
      Kouji Sakai, Naoya Nagata, Kimie Nomura, Takashi Irie, Kazuaki Takehara, Hiroaki Kanda, Yasushi Ami
    • Organizer
      The lst Influenza and other Infections
    • Int'l Joint Research
  • [Presentation] Septin-dependent entry of smooth endoplasmic reticulum into dendritic spines as a synaptic basis of persistent memory2019

    • Author(s)
      Ageta-Ishihara N, Takao K, Miyakawa T, Hioki H, Bito H, Inokuchi K, Kinoshita M.
    • Organizer
      OIST Mini-Symposium : The 16th International Membrane Research Forum
    • Invited
  • [Presentation] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-1, a simplified analog of debromoaplysiatoxin2019

    • Author(s)
      Ashida, Y., Yanagita, R. C., Kawanami, Y., Okamura, M., Dan, S., Irie, K.
    • Organizer
      新学術領域研究「化学コミュニケーションのフロンティア」第1回国際シンポジウム(ISCC2019)
    • Int'l Joint Research
  • [Presentation] Telomere as the starting point of anticancer drug discovery2019

    • Author(s)
      Seimiya, H.
    • Organizer
      11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research : Biology to Precision Medicine
    • Int'l Joint Research / Invited
  • [Presentation] Transgeneration of environmental chemicals-primed rat hyperactivity2019

    • Author(s)
      Masami Ishido
    • Organizer
      第9回アジア・オセアニア生理学会連合大会
    • Int'l Joint Research
  • [Presentation] Widefield sensory-evoked calcium imaging in excitatory and inhibitory neurons using a G-CaMP9a transgenic mouse2019

    • Author(s)
      Sakamoto M, Inoue M, Sakai K, Kobari S, Takemoto-Kimura S, Abe M, Sakimura K, Bito H
    • Organizer
      Japan-UK Neuroscience Symposium 2019
    • Int'l Joint Research
  • [Presentation] カオスから秩序へ-細胞内Ca2+光操作による機能創発2019

    • Author(s)
      八尾 寛
    • Organizer
      機能物性セミナー
    • Invited
  • [Presentation] グルタミン代謝制御遺伝子Glutaminase2が癌・老化関連疾患に及ぼす影響2019

    • Author(s)
      鈴木佐和子、横手幸太郎
    • Organizer
      第19会日本抗加齢医学会総会
    • Invited
  • [Presentation] シトクロムP450酸化酵素TleBを用いた硫黄を含む新奇indolactam類縁体化合物の創出2019

    • Author(s)
      森田 伊織、森 貴裕、阿部 郁朗
    • Organizer
      日本薬学会第139年会
  • [Presentation] センダイウイルスの宿主マウスでの病原性発現機序と宿主免疫系への貢献2019

    • Author(s)
      酒井宏治
    • Organizer
      8th Negative Strand Virus-Japan Symposium
  • [Presentation] 腸管放射線防護を目的とする末梢性NMDA受容体の解析2019

    • Author(s)
      大神 正次, 高井 伸彦, 二口充, 鵜澤 玲子, 平山 亮一
    • Organizer
      日本薬学会第139年会
  • [Presentation] てんかん~うつ・不安障害に至る分子発症メカニズムの解明2019

    • Author(s)
      藤田明子, 奥野貴哉, Siriporn Tangsdjai, 織田弥伽, 伊川正人, 加藤啓子
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] 沖縄県自生植物糸芭蕉(Musa balbisiana var. liukiuensis)の抗がん効果の検証2019

    • Author(s)
      吉本恵里、松本晴年、安藤さえこ、深町勝巳、酒々井眞澄
    • Organizer
      第139年会日本薬学会
  • [Presentation] 家系を対象とした次世代シーケンス解析による新規男性不妊症原因遺伝子の同定と遺伝子改変マウス作製による精子形成に関する検討2019

    • Author(s)
      野崎瑞貴、上殿千晴、古城公佑、内田将央、土屋春樹、山崎一恭、岩本晃明、佐藤陽一
    • Organizer
      日本アンドロロジー学会 第38回学術大会
  • [Presentation] 核小体による細胞分裂監視と腫瘍化進展制御2019

    • Author(s)
      河原 康一、川畑 拓斗、下川 倫子、白石 岳大、朝日 汰一
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム 成果発表会
  • [Presentation] 希少放射菌Streptoalloteichus tenebrarius NBRC 16177株が産生する二次代謝産物に関する研究2019

    • Author(s)
      星野 翔太郎、淡川 孝義、三橋 隆章、Wong Chin Piow、森田 洋行、阿部 郁朗
    • Organizer
      日本薬学会第139年会
  • [Presentation] 脂肪酸をリードとするSTAT4阻害抗がん物質の開発2019

    • Author(s)
      安藤さえこ、吉本恵里、深町勝巳、松本晴年、酒々井眞澄
    • Organizer
      第139年会日本薬学会
  • [Presentation] 神経細胞を近赤外光操作するバイオ・ナノデバイスシステムの開発2019

    • Author(s)
      八尾 寛
    • Organizer
      戦略的国際共同研究プログラム(SICORP)日本-シンガポール共同研究「バイオデバイス」領域平成27年度採択課題 国内成果報告会(2019/1/29) 東京
    • Invited
  • [Presentation] 睡眠覚醒調節と記憶の制御に関わる神経の活動記録と操作2019

    • Author(s)
      山中章弘
    • Organizer
      平成30年度生命融合科学教育部シンポジウム
    • Invited
  • [Presentation] 睡眠覚醒調節神経の機能的同定2019

    • Author(s)
      山中章弘
    • Organizer
      第92回日本薬理学会年会
    • Invited
  • [Presentation] 生理活性天然物をリードとするグアニン四重鎖を標的とした抗がん剤の創製研究2019

    • Author(s)
      馬悦, 中村貴大, 岡部幸子, 新家一男, 清宮啓之, 長澤和夫
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] 先天的腓骨神経欠損マウスの原因遺伝子の同定2019

    • Author(s)
      桝和子、加藤千賀、三谷優太、石井万由子、林康紀、村谷匡史、水野聖哉、杉山文博、高橋智、加藤秀樹、桝正幸
    • Organizer
      先端モデル動物支援プラットフォーム 成果発表会
  • [Presentation] 染色体整列関連因子CAMPは長期記憶の維持に関与する2019

    • Author(s)
      永井正義、家村顕自、吉川貴子、服部聡子、宮川剛、大隅典子、田中耕三
    • Organizer
      第36回染色体ワークショップ・第17回核ダイナミクス研究会
  • [Presentation] 体細胞分裂から減数分裂への細胞周期の切替え機構2019

    • Author(s)
      石黒啓一郎
    • Organizer
      The 36th Chromosome Workshop and the 17th Nuclear Dynamics
    • Int'l Joint Research
  • [Presentation] 短腸症候群モデルにおけるグアーガムの腸管上皮保護作用と腸内細菌2019

    • Author(s)
      藤井喬之、田中彩、形見祐人、上野正樹、千葉陽一、桑原知巳、今大路治之、大西峻、加治建、家入里志、下野隆一
    • Organizer
      第119回日本外科学会定期学術集会
  • [Presentation] 男性不妊症新規原因遺伝子の同定と遺伝子改変マウス作製による精子形成機能に関する検討2019

    • Author(s)
      野崎瑞貴、上殿千晴、古城公佑、内田将央、土屋春樹、岩本晃明、佐藤陽一
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] 軟骨細胞におけるKLF4のMMP13発現誘導メカニズム2019

    • Author(s)
      鬼頭昭吉、竹内優斗、阿部真土
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] 二量体型アルカロイドの立体化学多様化による中分子リード創製を目指して2019

    • Author(s)
      大栗博毅
    • Organizer
      平成30年度 文部科学省新学術領域 研究学術研究支援基盤形成「先端モデル動物支援プラットフォーム成果発表会」
    • Invited
  • [Presentation] 乳がん細胞のTGF-beta誘導性アポトーシスへの抵抗性に寄与する転写因子の解析.2019

    • Author(s)
      平田健介, 山田千愛, 安斎絵里菜, 柴崎美里, 本田拓也, 森井真理子, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第139回日本薬学会年会
  • [Presentation] 脳腫瘍放射線治療によって生じる脳壊死の作用機序ならびに新規防護剤の探索2019

    • Author(s)
      高井仲彦, 大神正次, 中村沙織, 大庭義史
    • Organizer
      平成30年度「先端モデル動物支援プラットフォーム成果発表会」
  • [Presentation] 排便に伴い誘発するクロコオロギの定型的行動2019

    • Author(s)
      浪花 啓右、杉本 靖博、大須賀 公一、青沼 仁志
    • Organizer
      計測自動制御学会第31回自律分散システムシンポジウム
  • [Presentation] 肺胞上皮細胞に対するメトトレキサートの抗がん効果と上皮間葉転換誘発作用の関連解析2019

    • Author(s)
      川見昌史、原田梨紗子、小島崇路、湯元良子、高野幹久
    • Organizer
      日本薬学会第139年会
  • [Presentation] Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy.2019

    • Author(s)
      Shimizu Y, Tamada S, Kato M, Hirayama Y, Takeyama Y, Iguchi T, Sadar MD, Nakatani T.
    • Organizer
      第28回泌尿器科分子細胞研究会
  • [Presentation] Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy.2019

    • Author(s)
      Shimizu Y, Tamada S, Kato M, Hirayama Y, Takeyama Y, Iguchi T, Sadar MD, Nakatani T.
    • Organizer
      第107回泌尿器科学会総会
  • [Presentation] Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy.2019

    • Author(s)
      Shimizu Y, Tamada S, Kato M, Hirayama Y, Takeyama Y, Iguchi T, Sadar MD, Nakatani T.
    • Organizer
      Genitourinary Cancers Symposium
    • Int'l Joint Research
  • [Presentation] ZO family proteins regulate epithelial polarity independent of Tight Junction strand assembly2019

    • Author(s)
      Tetsuhisa Otani, Shinsaku Tokuda, and Mikio Furuse
    • Organizer
      9th FAOPS Congress
    • Int'l Joint Research
  • [Presentation] Concise and Systematic Synthesis of Skeletally Diverse Indole Alkaloidal Scaffolds Bearing a Michael Acceptor Moiety2019

    • Author(s)
      Hirok, Kubota
    • Organizer
      The Third A3 Young Scientist & Young PI Meeting
  • [Presentation] Concise and Systematic Synthesis of Skeletally Diverse Indole Alkaloidal Scaffolds Bearing a Michael Acceptor Moiety2019

    • Author(s)
      Hiroki Kubota, Haruki Mizoguchi, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] 膜電位感受性蛍光プロープを用いた神経活動イメージング2019

    • Author(s)
      坂本雅行
    • Organizer
      第97回創薬科学セミナー・GTRセミナー
    • Invited
  • [Presentation] 小細胞肺がんの自然転移モデルにおいて転移形成に関与する因子の探索2019

    • Author(s)
      坂本修一、井上裕幸、大庭俊一、宇佐美伊保美、幸田泰子、水谷壮利、川田学
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム「成果発表会」
  • [Presentation] 3D analysis of the intracellular structures in growth cones using superresolution microscopy2019

    • Author(s)
      五十嵐 道弘
    • Organizer
      EMBO Molecular neuroscience
    • Int'l Joint Research
  • [Presentation] APC遺伝子の欠損による細胞競合の機能変容2019

    • Author(s)
      昆 俊亮、中井 一貴、田中 伸也、藤田 恭之
    • Organizer
      先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] Autonomous decentralized coordination in the disk of the green brittle Star2019

    • Author(s)
      脇田 大輝、浪花 啓右、早瀬 友美乃、青沼 仁志
    • Organizer
      計測自動制御学会第31回自律分散システムシンポジウム
  • [Presentation] Autophagy regulates lipid metabolism (Bioenergetics and NAFLD)2019

    • Author(s)
      小松雅明
    • Organizer
      Asia Pacific Association for Study of Liver (APASL) meeting
    • Int'l Joint Research / Invited
  • [Presentation] Causal evidence of BOLD-IMRI signal generation by astrocytes without neuronal activation2019

    • Author(s)
      高田則雄
    • Organizer
      The 2nd FRIS-TFC Joint Symposium : Unlocking the Brain from Engineering Approaches
    • Int'l Joint Research / Invited
  • [Presentation] Cellular mechanism of LUBAC-mediated NF-κB activation pathway2019

    • Author(s)
      Fuminori Tokunaga
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research / Invited
  • [Presentation] Chemo-enzymatic Synthesis of Saframycins : Expansion of substrate tolerance2019

    • Author(s)
      Ryoko Komatsu, Ryo Tanifuji, Takamitsu Honda, Ryutaro Asano, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Control of mRNA translation by hnRNP A/B variants2019

    • Author(s)
      Nanaho Fukuda, Piergiorgio Percipalle, Kevin Czaplinski, Yasumasa Ishida, Tomoyuki Fukuda, and Toshikuni Sasaoka
    • Organizer
      第8回生理研-霊長研-脳研合同シンポジウム
  • [Presentation] Design and Synthesis of C2-Symmetric Alkaloidal Chiral Amphiphiles and Configurational Effects on Self-Assembly2019

    • Author(s)
      Nana Tsuchiya, Yunosuke Ryu, Takahiro Muraoka, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Design, synthesis, temperature dependent self-assembly of aza-artemisinins2019

    • Author(s)
      Hikari Koi, Norihito Takahashi, Yasufumi ; Fuchi, Satoru Karasawa, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Development of innovative method for an all-optical electrophysiology to measure and manipulate neural activity2019

    • Author(s)
      Sakamoto M, Sudo Y
    • Organizer
      International Symposium of Brain/MINDS ISBM2019
    • Int'l Joint Research
  • [Presentation] Development of the Second Generation Synthetic Process of Aza-artemisinins2019

    • Author(s)
      Naoya Matsuoka, Hikari Koi, Norihito Takahashi, BONEPALLY, Karunakar, Reddy, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Differential characteristics of D1 and D2-type medium spiny neuron via cortico-striatal stimulation2019

    • Author(s)
      Inagaki R, Sasagawa M, Homma N, Osanai M
    • Organizer
      9th FAOPS Congress
    • Int'l Joint Research
  • [Presentation] Divergent Synthesis of Skeletally Distinct Alkaloidal Scaffolds via Zn(OTf)2-mediated Alkyne Activation2019

    • Author(s)
      Sadaiwa Yorimoto ; Yoshiaki Tsunekawa, Tomoya Ichino, Akira Tsubouchi, Satoshi Maeda, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Downregulation of MTHFD2, an enzyme of one-carbon metabolism in mitochondria, inhibits tumor growth and cancer stem-like properties.2019

    • Author(s)
      Tatsunori Nishimura, Asuka Nakata, Xiaoxi Chen, Kurumi Nishi, Makiko Meguro-Horike, Soichiro Sasaki, Kenji Kita, Shin-ichi Horike, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Takahiko Murayama, Susumu Kohno, Chiaki Takahashi, Naofumi Mukaida, Seiji Yano, To
    • Organizer
      11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research : From Biology to Precision Medicine
    • Int'l Joint Research
  • [Presentation] Dysfunction of Tsukushi leads to hydrocephalus by altering neurogenesis in the subventricular zone.2019

    • Author(s)
      Naofumi Ito, Mohammad Asrafuzzaman Riyadh, Ayako Ito, Shah Adil Ishtiyaq Ahmad, Mohammad Badrul Anam, Kunimasa Ohta
    • Organizer
      Molecular neurodegeneration joint symposium
    • Invited
  • [Presentation] Genome wide screen for the genes involved in brain tumor formation2019

    • Author(s)
      高祖秀登
    • Organizer
      先端モデル動物支援プラットフォーム成果発表会
  • [Presentation] Identification and characterization of small-molecule LUBAC inhibitors, HOIPINs2019

    • Author(s)
      Oikawa D, Katsuya K, Hanada K, Sakamoto S, Tokunaga F.
    • Organizer
      1st International symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks.
    • Int'l Joint Research
  • [Presentation] Increased level of maternal RORγt enhances effect of poly(I : C) to induce fetal loss2019

    • Author(s)
      當銘幸貴、永田怜、佐々木哲也、高橋智、武井陽介
    • Organizer
      4th Annual Anatomy Group Meeting
  • [Presentation] Interval timing of visual and auditory cues for duration discrimination in monkey prefrontal cortex2019

    • Author(s)
      千葉惇、守田和紀、生塩研一、稲瀬正彦
    • Organizer
      FAOPS2019
    • Int'l Joint Research
  • [Presentation] KLF4は頭頚部正常発生に必須である2019

    • Author(s)
      竹内優斗、藤川順司、立田咲百合、阿部真土
    • Organizer
      第12回大阪大学医学系若手フォーラム
  • [Presentation] MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移に伴う認知・行動異常の解析2019

    • Author(s)
      Razib Hossain, 多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 尾嶋 大喜, 高橋 弘雄, 岸本泰司, 山本 融
    • Organizer
      日本薬学会第139年会
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019

    • Author(s)
      平尾敦
    • Organizer
      11th AACR-JCA joint conference
    • Int'l Joint Research / Invited
  • [Presentation] Ongoing motor information embedded in a network dynamics ofprimate primary somatosensory neurons.2019

    • Author(s)
      望月圭、中陦克己、稲瀬正彦、村田哲
    • Organizer
      FAOPS2019
    • Int'l Joint Research
  • [Presentation] Optical manipulation of intracellular Ca2+ dynamics2019

    • Author(s)
      Hiromu Yawo
    • Organizer
      The 15th German-Japanese Colloquium, “Nano Lifescience”
    • Int'l Joint Research / Invited
  • [Presentation] Organelle-optogenetics-direct manipulation of intracellular Ca2+ dynamics by light.2019

    • Author(s)
      Hiromu Yawo, Toshifumi Asano, Hiroyuki Igarashi, Toru Ishizuka
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019) from March 28-31, 2019, Kobe, Japan
    • Int'l Joint Research / Invited
  • [Presentation] OTUD1, and OTU family deubiquitinase, is involved in innate immune responses2019

    • Author(s)
      Keidai Komakura, Eiji Goto, Daisuke Oikawa, Takanori Abe, Fuminori Tokunaga
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research
  • [Presentation] Prefrontal-Enriched SLITI Expression in Primate Cortex Established during the Postnatal Development2019

    • Author(s)
      Tetsuya Sasaki, Yusuke Komatsu, Akiya Watakabe, Tetsuo Yamamori
    • Organizer
      he 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019)
    • Int'l Joint Research
  • [Presentation] Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution2019

    • Author(s)
      Takayoshi Awakawa, Haruo Ikeda, Kazuo Shinya, Wen Liu. Ikuro Abe
    • Organizer
      2nd China-Japan Joint Symposium on Natural Product Biosynthesis
    • Int'l Joint Research
  • [Presentation] Requirements for multivalent Yb body assembly in piRNA-mediated transposon silencing in Drosophila2019

    • Author(s)
      塩見 美喜子
    • Organizer
      40th LORNE GENOME CONFERENCE 2019
    • Int'l Joint Research / Invited
  • [Presentation] Responses to hypercapnia and hypoxia of Phox2b-positive cells in the ventral medulla of newborn rats.2019

    • Author(s)
      Hiroshi Onimaru, Keiko Ikeda, Hiroyuki Igarashi, Hiromu Yawo, Kazuto Kobayashi, Satoru Arata, Kiyoshi Kawakami.
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019) from March 28-31, 2019, Kobe, Japan
    • Int'l Joint Research
  • [Presentation] RORgt過剩発現マウスにおけるpoly(i : c)誘導性流産率の上昇2019

    • Author(s)
      當銘 幸貴、佐々木 哲也、越田 隆介、武井 陽介
    • Organizer
      第124回 日本解剖学会総会・全国学術集会
  • [Presentation] Screening and analysis of novel linear polyubiquitin chain binding proteins based on wheat cell-free 20K-HUPA2019

    • Author(s)
      Kazuya Nagano, Hirotaka Takahashi, Fuminori Tokunaga, Tatsuya Sawasaki
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research
  • [Presentation] Stereochemical Diversificaion of Dimeric Alkaloids : Towards Integration of Natural Product Chemistry, Chemical Biology, and Supramolecular Chemistry2019

    • Author(s)
      Hiroki Oguri
    • Organizer
      Asian Chemical Biology Initiative 2019 Myanmer Meeting
    • Int'l Joint Research / Invited
  • [Presentation] Stereo-controlled Synthesis of Alkaloidal Scaffolds through Assembly of Aromatic Amino Acid Components2019

    • Author(s)
      Takamitsu Honda, Ryo Tanifuji, Ryoko Komatsu, Hiroki, Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] Subquinocin, a small moleculae inhibitor for USPs, promotes NF-κB signal by stabilization of M1-linked polyubiquitin2019

    • Author(s)
      Hirotaka Takahashi, Satoshi Yamanaka, Yusuke Sato, Daisuke Oikawa, Shuya Fukai, Fuminori Tokunaga, Tatsuya Sawasaki
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research
  • [Presentation] Synthesis of Alkaloidal Skeletons by Regioselective Dimerizations of Dihydropyridines2019

    • Author(s)
      Yuta Arai, Ryo Watanabe, Soushi Fujikawa, Erina Hosono, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
  • [Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019

    • Author(s)
      平尾敦
    • Organizer
      2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
    • Int'l Joint Research / Invited
  • [Presentation] TLR3-mTORシグナルによるヘルペス脳炎の制御2019

    • Author(s)
      佐藤亮太、加藤哲久、千村崇彦、斉藤伸一郎、柴田琢磨、村上祐輔、福井竜太郎、池上恒雄、真鍋俊也、川口寧、三宅健介
    • Organizer
      東京免疫フォーラム
  • [Presentation] Towards Divergent Synthesis of Manzamine-type Alkaloidal Skeletons : Regio-controlled Dimerizations of Dihydropyridines2019

    • Author(s)
      Yuta Arai
    • Organizer
      The Third A3 Young Scientist & Young PI Meeting
  • [Presentation] tRNA modification in translation control and human diseases.2019

    • Author(s)
      魏 范研
    • Organizer
      6th Symposium Smart-Aging Research Center.
    • Invited
  • [Presentation] オートファジー欠損マウスの解析から何がわかったか?2019

    • Author(s)
      小松雅明
    • Organizer
      2019年日本毒性病理学会学術集会
    • Invited
  • [Presentation] がん細胞における染色体不安定性は増殖選択圧を受けた際の増殖優位性獲得に寄与する2019

    • Author(s)
      家村顕自, 田中耕三
    • Organizer
      第36回染色体ワークショップ
  • [Presentation] コンドロイチン硫酸合成酵素ノックアウトマウス解析2019

    • Author(s)
      五十嵐 道弘
    • Organizer
      第3回先端モデル動物支援プラットフォーム成果発表会
    • Invited
  • [Presentation] 細胞のサイズ調節機構と生理的意義2019

    • Author(s)
      山本一男、宮崎利香、早田正和
    • Organizer
      サイズ生物学ワークショップ2019
  • [Presentation] 上皮間葉転換と細胞内代謝リモデリングのクロストーク2019

    • Author(s)
      山口憲孝, 山口直人, 高野博之
    • Organizer
      第139回日本薬学会年会
    • Invited
  • [Presentation] マウスモデルを用いたプラセポおよびノセポ反応条件づけの開発と評価2019

    • Author(s)
      青野 仁美, 藤原 友佳, 尾嶋 大喜, 山本 融, 岸本泰司
    • Organizer
      日本薬学会第139年会
  • [Presentation] 密着結合のジオメトリー制御による傍細胞輸送効率の最適化2019

    • Author(s)
      大谷哲久
    • Organizer
      研究会「数理科学と生命科学の融合」
    • Invited
  • [Presentation] ローズマリーの加熱処理によって生成された新規化合物の構造解析と生理活性について2019

    • Author(s)
      酒見裕香、Bu-chin Yu, 濱島留梨子、森岡優子、山中大介、伯野史彦、高橋伸一郎、新藤一敏
    • Organizer
      2019年度農芸化学会大会
  • [Presentation] 異種間移植マーモセット卵巣由来卵子による受精卵作出法の検討2019

    • Author(s)
      中務胞、宮本純、藤澤信義、夏目里恵、三浦詩織、阿部学、三輪美樹、中村克樹、崎村建司、笹岡俊邦
    • Organizer
      第8回生理研-霊長研-脳研合同シンポジウム
  • [Presentation] 新潟大学における中型実験動物の飼育管理と利用2019

    • Author(s)
      三浦詩織、藤澤信義、宮本純、小田佳奈子、福田七穂、内山澄香、田中稔、山本美丘、作間赳法、阿部光寿、齊藤奈英、鈴木康浩、中務胞、夏目里恵、小林隆、三浦宏平、崎村健司、若井俊文、笹岡俊邦
    • Organizer
      第8回生理研-霊長研-脳研合同シンポジウム
  • [Presentation] 新規LUBAC阻害剤の同定と合成展開による阻害能亢進2019

    • Author(s)
      及川大輔
    • Organizer
      第2回ユビキチン研究会
  • [Presentation] 成長ホルモン産生下垂体腺腫に対する術後照射18年後にsarcomatous transformationを来した一例2019

    • Author(s)
      岡田正康、米岡有一郎、大石誠、藤井幸彦
    • Organizer
      第29回日本間脳下垂体腫瘍学会
  • [Presentation] 先導端におけるアクチン東の空間分布が局所的エンドサイトーシス、受容体局在を決定付ける2019

    • Author(s)
      野住 素広
    • Organizer
      2019年生体運動研究合同会議
  • [Presentation] 転写共役因子VGLL3による上皮間葉転換の制御機構の解析.2019

    • Author(s)
      高倉勇気, 杉野歩美, 岩澤脩斗, 平田健介, 岡田和之, 竹洞裕貴, 平井直人, 堀 直人, 町田萌香, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第139回日本薬学会年会
  • [Presentation] 脳と栄養の学際領域研究-脂質栄養から脳の謎に挑むー2019

    • Author(s)
      酒寄信幸
    • Organizer
      第8回東北脳科学ウィンタースクール
    • Invited
  • [Presentation] 霊長類前頭前皮質に特異的に発現する遺伝子の解析2019

    • Author(s)
      佐々木 哲也、小松 勇介、渡我部 昭哉、山森 哲雄
    • Organizer
      第124回 日本解剖学会総会・全国学術集会
  • [Presentation] D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2018

    • Author(s)
      笹岡 俊邦、佐藤 朝子、知見 聡美、大久保 直、齊藤 奈英、福田 七穂、阿部 学、川村 名子、小田 佳奈子、佐藤 俊哉、藤澤 信義、山口 瞬、田井中 一貴、崎村 建司、南部 篤
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2018

    • Author(s)
      笹岡 俊邦、齊藤 奈英、知見 聡美、佐藤 朝子、大久保 直、福田 七穂、阿部 学、川村 名子、小田 佳奈子、佐藤 俊哉、藤澤 信義、山口 瞬、田井中 一貴、崎村 建司、南部 篤
    • Organizer
      科学研究費補助金「新学術領域研究(研究領域提案型)」非線形発振現象を基盤としたヒューマンネイチャーの理解「オシロロジー」2018年度第2回領域会議
  • [Presentation] マウスにおける減数分裂の開始機構2018

    • Author(s)
      石黒啓一郎
    • Organizer
      エピジェネティクス研究会
  • [Presentation] マウスにおける減数分裂の開始機構2018

    • Author(s)
      石黒啓一郎
    • Organizer
      モロシヌス研究会2018
  • [Presentation] マウスにおける減数分裂の開始機構2018

    • Author(s)
      石黒啓一郎
    • Organizer
      2018日本分子生物学会年会
    • Invited
  • [Presentation] A novel germ cell-specific factor, MEIOSIN, recruits STRA8 to direct initiation of meiosis in mammals2018

    • Author(s)
      Kei-ichiro Ishiguro
    • Organizer
      CSHL Meeting : Germ Cell
    • Int'l Joint Research
  • [Presentation] A novel germ cell-specific factor, MEIOSIN, recruits STRA8 to direct initiation of meiosis in mammals2018

    • Author(s)
      Kei-ichiro Ishiguro
    • Organizer
      第13回生命医科学研究所ネットワーク国際シンポジウム
    • Int'l Joint Research / Invited
  • [Presentation] G-quadruplex as a molecular target for cancer therapy2018

    • Author(s)
      Seimiya, H.
    • Organizer
      The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
    • Int'l Joint Research / Invited
  • [Presentation] G-quadruplex as a molecular target for cancer therapy2018

    • Author(s)
      Seimiya, H.
    • Organizer
      The 41st Annual Meeting of the Molecular Biology Society of Japan
    • Invited
  • [Presentation] 天然脂肪酸を由来とする新規抗がん物質の作用機序解析2018

    • Author(s)
      安藤さえこ、深町勝巳、松本晴年、酒々井眞澄
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 劣性(潜性)遺伝形式で多血症の症状を示す自然発生突然変異マウス『pocy』の解析2018

    • Author(s)
      荒木正健、古閑成美、林田隆成、北元優梨、慶田貴子、吉信公美子、鳥越大輔、中村直子、柳久美子、要匡、荒木喜美
    • Organizer
      日本遺伝学会第90回大会
  • [Presentation] 心不全、肥満における褐色脂肪不全の意義2018

    • Author(s)
      清水 逸平
    • Organizer
      第23回アディポサイエンスシンポジウム
    • Invited
  • [Presentation] 心不全、肥満における褐色脂肪不全の意義2018

    • Author(s)
      清水 逸平
    • Organizer
      第91回日本生化学会大会
  • [Presentation] 新規オートファジー活性計測プローブ発現マウスを用いた生体での活性測定2018

    • Author(s)
      神田侑季、森下英晃、濱祐太郎、阿部学、崎村建司、水島昇
    • Organizer
      第18回東京大学生命科学シンポジウム
  • [Presentation] 新規オートファジー活性計測プローブ発現マウスを用いた生体での活性測定2018

    • Author(s)
      神田侑季、森下英晃、濱祐太郎、阿部学、崎村建司、水島昇
    • Organizer
      新学術領域研究「学術研究支援基盤形成」先端モデル動物支援プラットフォーム 若手支援技術講習会
  • [Presentation] 天然脂肪酸を由来とする新規抗がん物質の作用機序解析2018

    • Author(s)
      安藤さえこ、松本晴年、深町勝巳、酒々井眞澄
    • Organizer
      第45回日本毒性学会学術年会
  • [Presentation] Excessive decrease in cerebral blood volume during hypothermia can indicate adverse neurological outcome in asphyxiated piglet.2018

    • Author(s)
      Nakamura S, Jinnai W, Kusaka T, et al
    • Organizer
      Pediatric Academic Societies Meeting in Toronto 2018
    • Int'l Joint Research
  • [Presentation] A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging in vivo.2018

    • Author(s)
      Sakamoto M, Inoue M, Sakai K, Kobari S, Takemoto-Kimura S, Abe M, Sakimura K, Bito H
    • Organizer
      第41回日本神経科学大会
  • [Presentation] A novel STRA8 interacting factor, MEIOSIN1, directs initiation of meiosis in mammals2018

    • Author(s)
      Kei-ichiro Ishiguro
    • Organizer
      Joint Annual Meeting of 51st JSDB and 70th JSCB
  • [Presentation] A novel therapeutic option for synovial sarcoma using alpha-radiolabeled FZD10 antibody2018

    • Author(s)
      李 惠子, 神田 浩明, 長山 聡, 片桐 豊雅, 中村 祐輔, 長谷川 純崇
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] A novel transcription factor, MEIOSIN, recruits STRA8 to direct initiation of meiosis in mammals2018

    • Author(s)
      Kei-ichiro Ishiguro
    • Organizer
      2018 Meiosis Conference GRC meiosis
    • Int'l Joint Research / Invited
  • [Presentation] A postsynaptic dysregulation in hippocampal granule cells that underlies spatial discrimination defect.2018

    • Author(s)
      Ageta-Ishihara N, Fukazawa Y, Takao K, Miyakawa T, Bito H, Inokuchi K, Kinoshita M.
    • Organizer
      The Joint Congress of the 40th Annual Meeting of Japanese Society of Biological Psychiatry and the 61st Annual Meeting of the Japanese Society for Neurochemistry
  • [Presentation] Alcadein αノックアウトマウスは加齢で網膜神経節細胞が脱落する2018

    • Author(s)
      中野裕貴, 小野葵, 小林守, 高砂縁, 村山千明, 尾嶋大喜, 山本融, 廣岡一行
    • Organizer
      日本眼科学会総会
  • [Presentation] ALK陽性肺がん獲得耐性から考えるキナーゼ進化2018

    • Author(s)
      片山 量平
    • Organizer
      第41回日本呼吸器内視鏡学会学術集会
    • Invited
  • [Presentation] An activity-regulated septin subunit SEPT3 is required for the entry of sER into dendritic spines and spatial discrimination.2018

    • Author(s)
      Ageta-Ishihara N, Fukazawa Y, Takao K, Miyakawa T, Bito H, Inokuchi K, Kinoshita M.
    • Organizer
      Gordon Research Conference “Cell Biology of the Neuron”
    • Int'l Joint Research
  • [Presentation] Anticancer drug resistance caused by cancer cell evolution and diversity2018

    • Author(s)
      片山 量平
    • Organizer
      第41回 日本分子生物学会年会
    • Invited
  • [Presentation] Area-specific laminar organization is regulated by thalamocortical axons through axon-derived NRN1 and VGF in developing neocortex2018

    • Author(s)
      Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Nobuhiko Yamamoto, Kenji Shimamura
    • Organizer
      22nd Biennial Meeting of the International Society of Developmental Neuroscience
    • Int'l Joint Research
  • [Presentation] Biomarker-based screening identified BET inhibitor JQ1 as a neuroprotective compound for Parkinson's disease2018

    • Author(s)
      片浦哲志, 斉木臣二, 服部信孝, 井本正哉
    • Organizer
      The 9th Japan-Korea Chemical Biology Symposium
    • Int'l Joint Research
  • [Presentation] Change in Electromyographic Patterns After Leg Amputation in the Cricket2018

    • Author(s)
      D. Owaki, Y. Sugimoto, A. Ishiguro and H. Aonuma
    • Organizer
      International Congress for Neuroethology
    • Int'l Joint Research
  • [Presentation] Characterization of chimeric TFE3 transcription factors found in Xpll. 2 translocation renal cell carcinoma2018

    • Author(s)
      Takanobu Motoshima, Yorifumi Satou, Paola Miyazato, Hisashi Hasumi, Ying Huang, Tsuyoshi Kadomatsu, Masahiro Yao, Yoji Nagashima, Mitsuko Furuya, Yuchi Oike, Laura S Schmidt, Tomomi Kamba, W Marston Linehan, Masaya Baba
    • Organizer
      American Urological Association's 2018 Annual Meeting
    • Int'l Joint Research
  • [Presentation] Chemical genomic analysis on autophagic regulation mechanism in human lung cancer A549 cells2018

    • Author(s)
      片浦哲志, 井本正哉
    • Organizer
      30th EORTC-NCI-AACR Symposium
    • Int'l Joint Research
  • [Presentation] D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2018

    • Author(s)
      笹岡 俊邦, 佐藤 朝子, 知見 聡美, 大久保 直, 阿部 学, 川村 名子, 齊藤 奈英, 小田 佳奈子, 作間 赳法, 内山 澄香, 阿部 光寿, 田中 稔, 山本 美丘, 神保 幸弘, 佐藤 俊哉, 藤澤 信義, 崎村 建司, 南部 篤
    • Organizer
      第41回日本神経科学大会
  • [Presentation] De novo inheritance of environmental chemicals-primed rat hyperactivity2018

    • Author(s)
      Masami Ishido
    • Organizer
      第41回日本神経科学会
  • [Presentation] Detection, prediction, and investigation of the resistance mechanisms to EGFR-TKIs in EGFR mutated NSCLC2018

    • Author(s)
      片山 量平、内堀 健、有安 亮、栁谷 典子、西尾 誠人
    • Organizer
      第59回 日本肺癌学会学術集会
    • Invited
  • [Presentation] Disease Modeling of Refractory Epilepsy using iPSCs2018

    • Author(s)
      Hirose S
    • Organizer
      The 40th Annual Meeting of Japanese Society of Biological Psychiatry/The 61st Annual Meeting of the Japanese Society for Neurochmistry
  • [Presentation] Disoriented choline metabolism promotes pathologies in the failing heart.2018

    • Author(s)
      清水 逸平
    • Organizer
      The 62nd Annual Scientific Meeting of The Korean Society of Cardiology
  • [Presentation] DNA polymerase β is required for postnatal hippocampal development and function.2018

    • Author(s)
      Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
    • Organizer
      Cold Spring Harbor Asia meeting on Latest Advance in Development & Function of Neuronal Circuit
    • Int'l Joint Research
  • [Presentation] Drug repurposing : overcoming the acquired resistance with other target inhibitors2018

    • Author(s)
      Ryohei Katayama, Bo Gong, Koutaroh Okada, Ken Uchibori, Makoto Nishio, Naoya Fujita
    • Organizer
      The 6th JCA-AACR Special Joint Conference
    • Int'l Joint Research / Invited
  • [Presentation] Effectiveness of Hydrogen Inhalation in Neonatal Hypoxic-ischemic Piglet Model2018

    • Author(s)
      Htun Y, Nakamura S, Kusaka T, et al.
    • Organizer
      Pediatric Academic Societies Meeting in Toronto 2018
    • Int'l Joint Research
  • [Presentation] Effectiveness of Hydrogen Inhalation in neonatal hypoxic-ischemic piglet model.2018

    • Author(s)
      Htun Y, Nakamura S, Kusaka T, et al.
    • Organizer
      The 43th Annual Meeting of Japanese Society for Microcirculation
    • Int'l Joint Research
  • [Presentation] EGFRチロシンキナーゼを標的とするラメラリンN誘導体の設計・合成・活性評価2018

    • Author(s)
      福田勉、石橋郁人、奥裕介、西谷直之、上原至雅、岩尾正倫
    • Organizer
      第48回複素環化学討論会
  • [Presentation] ER陽性乳癌細胞におけるFOXA1によるTGF-beta誘導性細胞死の抑制機構の解析2018

    • Author(s)
      山口憲孝, 山口直人.
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] From molecule to mind-disentangling the brain with light.2018

    • Author(s)
      Hiromu Yawo, Toru Ishizuka
    • Organizer
      第41回日本神経科学大会
    • Invited
  • [Presentation] Functional analysis of the novel WASP mutation resulting in X-linked congenital neutropenia2018

    • Author(s)
      Masayuki Kobayashi, Chanda Bidisha, Muneyoshi Futami., Mizuho Yamashita, Mitsuhiro Hirano, Kazuaki Yokoyama, Yoichi Imai, Eigo Yusa, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Arinobu Tojo
    • Organizer
      80th annual meeting of the JSH
  • [Presentation] GAD knockout rats for a model of psychiatric disorders2018

    • Author(s)
      Kazuyuki Fujihara, Yuchio Yanagawa
    • Organizer
      第40回日本生物学的精神医学会、第61回日本神経化学会大会 合同年会
    • Invited
  • [Presentation] GAD65/67二重変異ラットの作製と解析2018

    • Author(s)
      姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、宮坂佳樹、真下知士、柳川右千夫
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Genome Stability by DNA polymerase b in Cortical Development2018

    • Author(s)
      菅生紀之
    • Organizer
      第41回日本神経科学大会 シンポジウム「大脳皮質の形成と機能発現を担う遺伝子制御システムの新展開」
    • Invited
  • [Presentation] G-quadruplex nucleic acid as a molecular target for cancer therapy2018

    • Author(s)
      Seimiya, H.
    • Organizer
      The 77th Annual Meeting of Japanese Cancer Association (JCA), Symposium
    • Invited
  • [Presentation] Growth cone phosphoproteomics reveals that JNK-dependent phosphorylation of GAP-43 is specific to the growing axon2018

    • Author(s)
      河嵜 麻実
    • Organizer
      コールドスプリングハーバーアジアミーティング
    • Int'l Joint Research
  • [Presentation] Hmga2 promotes the development of MDS/MPN in the absence of Tet22018

    • Author(s)
      Bai J. Yokomizo-Nakano T, Kubota S, Iwama A, Harada H, Sashida G
    • Organizer
      第80回日本血液学会学術集会
  • [Presentation] Hydrogen Inhalation improved Motor Function in Neonatal Hypoxic Ischemic Piglet Model.2018

    • Author(s)
      Htun Y, Nakamura S, Kusaka T, et al.
    • Organizer
      第54回日本周産期・新生児医学会学術集会
  • [Presentation] Identification and arrhythmogenic significance of a novel TMEM168 mutation in Brugada syndrome.2018

    • Author(s)
      Dimitar P. Zankov、扇田久和
    • Organizer
      第2回日本循環器学会基礎研究フォーラム
  • [Presentation] Identification of a novel nuclear factor for initiation of meiosis2018

    • Author(s)
      Kei-ichiro Ishiguro
    • Organizer
      8th International Symposium on the Biology of Vertebrate Sex Determination
    • Int'l Joint Research
  • [Presentation] Inheritance of environmental chemicals-primed rat hyperactivity2018

    • Author(s)
      Masam Ishido
    • Organizer
      第91回日本生化学会
  • [Presentation] Inhibitors of pituitary differentiation reduce cell proliferation of small cell lung carcinomas2018

    • Author(s)
      Yusuke Suenaga, Masato Shingyoji, Sotaro Kanematsu, Toshihiko Iizasa, Mamoru Kato, Sana Yokoi
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Integarting neuronal ensembles constitute and replay hippocampal engram.2018

    • Author(s)
      Ghandour K, Ohkawa N, Fung CCA, Asai H, Saitoh Y, Takekawa T, Okubo-Suzuki R, Soya S, Nishizono H, Matsuo M, Sato M, Ohkura M, Nakai J, Hayashi Y, Sakurai T, Osanai M, Kitamura T, Fukai T, Inokuchi K
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Involvement of FOXAI in resistance to TGF-beta-induced apoptosis in estrogen receptor-positive breast cancer cells.2018

    • Author(s)
      Yamaguchi, N, Takakura, Y., Hirata, K., Takano, H., and Yamaguchi, N.
    • Organizer
      The 2018 ASCB/EMBO Meeting
    • Int'l Joint Research
  • [Presentation] JNK-dependent phosphorylation sites of GAP-43 is a marker of axon growth/regeneration, revealed by growth cone phosphoproteomics2018

    • Author(s)
      河嵜 麻実
    • Organizer
      Society for neuroscience
    • Int'l Joint Research / Invited
  • [Presentation] KLF4 in skeletal development and disease2018

    • Author(s)
      Abe M
    • Organizer
      Yonsei Biomedical Dialogue
    • Int'l Joint Research / Invited
  • [Presentation] KLF4は軟骨細胞においてHDAC3を介してMMP13の発現を制御する2018

    • Author(s)
      鬼頭昭吉、竹内優斗、阿部真土
    • Organizer
      第36回日本骨代謝学会学術集会
  • [Presentation] Maintenance of genome stability by DNA polymerase β in necessary for postnatal development in cortical and hippocampal neurons2018

    • Author(s)
      Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
    • Organizer
      第41回日本神経科学大会
  • [Presentation] MEIOSIN-STRA8複合体は体細胞分裂型から減数分裂型のcell cycleへの切り替えを制御する2018

    • Author(s)
      石黒啓一郎
    • Organizer
      成果取りまとめ公開シンポジウム 「生殖細胞のエビゲノムダイナミクスとその制御」
  • [Presentation] Models of cancer stem cells to understand the tumor population dynamics and develop novel therapy2018

    • Author(s)
      Nobuhiro Okada
    • Organizer
      国立六大学とタイの大学等とのジョイントシンポジウム
    • Int'l Joint Research
  • [Presentation] Molecular analysis of the mutant gene for the peroneal muscular atrophy mouse先天的腓骨神経欠損マウスの原因遺伝子の同定2018

    • Author(s)
      桝和子, 加藤千賀, 三谷優太, 林康紀, 村谷匡史, 水野聖哉, 高橋智, 加藤秀樹, 桝正幸
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Novel urinary biomarker for Xpll. 2 translocation renal cell carcinoma2018

    • Author(s)
      Ryoma Kurahashi, Tsuyoshi Kadomatsu, Masaya Baba, Chiaki Hara, Motoyoshi Endo, Yuichi Oike, Tomomi Kamba
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] p19Arfに存在する非同義置換多型は腫瘍悪性化を制御する2018

    • Author(s)
      齋藤 慈、奥村 和弘、磯貝恵理子、荒木 喜美、若林 雄一
    • Organizer
      第77回日本癌学会総会
  • [Presentation] p19Arfに存在する非同義置換多型は腫瘍悪性化を制御する2018

    • Author(s)
      斎藤慈、奥村和弘、磯貝恵理子、荒木喜美、若林雄一
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Phosphoproteomics of the mammalian growth cone reveals that phosphorylation of GAP-43 by JNK is specific to the growing/regenerating axon2018

    • Author(s)
      五十嵐 道弘
    • Organizer
      ASCB/EMBO2018 meeting
    • Int'l Joint Research
  • [Presentation] Phosphorylation profiles of neuronal growth cones revealed by phosphoproteomics2018

    • Author(s)
      五十嵐 道弘
    • Organizer
      Gordon Ressearch Conference
    • Int'l Joint Research
  • [Presentation] Phosphorylation-dependent molecular marker for axon growth/regeneration in rodents and primates2018

    • Author(s)
      Masayasu Okada, Asami Kawasaki, Atsushi Tamada, Yutaka Yoshida, Takeuchi Kosei, Yukihiko Fujii, Michihiro Igarashi.
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Precision medicine though stem cells2018

    • Author(s)
      Hirose S
    • Organizer
      12th Asian and Oceanian epilepsy congress
    • Int'l Joint Research
  • [Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons2018

    • Author(s)
      Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Mito T, Matsumoto H, Miyakawa T, Nakada K.
    • Organizer
      第41回日本分子生物学会年会
    • Invited
  • [Presentation] Pterostilbene inhibits cancer stem cells by increase of oxidative stress2018

    • Author(s)
      Mori S, Kishi S, Fujiwara-Tani R, Kondo Y, Honoki K, Kuniyasu H
    • Organizer
      77th Annual Meeting of Japanese Association for Cancer
  • [Presentation] Quantitative study of cross-modal plasticity in the rat somatosensory perception using optogenetics.2018

    • Author(s)
      Kenta Abe, Hiromu Yawo
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Regulation of hypoxia response pathway by chimeric TFE3s in Xp11. 2 translocation renal cell carcinoma2018

    • Author(s)
      Wenjuan Ma, Takanobu Motoshima, Yorifumi Satou, Hisashi Hasumi, Tsuyoshi Kadomatsu, Ryoma Kurahashi, Mitsuko Furuya, Masahiro Yao, Laura S Schmidt, W Marston Linehan, Yuichi Oike, Tomomi Kamba, Masaya Baba
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Resistance mechanisms of ALK/EGFR-TKIs or immune checkpoint inhibitors in lung cancer, and the potential therapeutic strategies to overcome the resistance.2018

    • Author(s)
      Ryohei Katayama, Koutaroh Okada, Bo Gong, Ken Uchibori, Makoto Nishio, and Naoya Fujita
    • Organizer
      The 23rdTaiwan Joint Cancer Conference
    • Int'l Joint Research / Invited
  • [Presentation] Retinal Ganglion Cell Loss in Alcadein α Knockout Mice2018

    • Author(s)
      Yuki Nakano, Aoi Ono, Mamoru Kobayashi, Yukari Takasago, Chiaki Murakami, Daiki Ozima, Tohru Yamamoto, Kazuyuki Hirooka
    • Organizer
      ARVO 2018 : The Association for Research in Vision and Ophthalmology Annual Meeting
    • Int'l Joint Research
  • [Presentation] SGLT2阻害薬は腎貧血モデルラットの血中エリスロボエチン濃度に影響を与えない2018

    • Author(s)
      山﨑大輔、中野大介、小西啓夫、西山 成
    • Organizer
      第41回日本高血圧学会総会
  • [Presentation] Spatial discrimination defects caused by chronic, systemic loss of a septin subunit is recapitulated by its acute, local depletion in the hippocampal dentate gyrus2018

    • Author(s)
      Ageta-Ishihara N, Takao K, Miyakawa T, Hioki H, Bito H, Inokuchi K, Kinoshita M.
    • Organizer
      第1回国際シンポジウム “Towards Understanding INDIVIDUALITY”
    • Int'l Joint Research
  • [Presentation] Studies to uncover the molecular mechanism for cancer development in Xp11. 2 translocation renal cell carcinoma2018

    • Author(s)
      Masaya Baba, Wenjaun Ma, Takanobu Motoshima, Yorifumi Satou, Hisashi Hasumi, Tsuyoshi Kadomatsu, Mitsuko Furuya, Yoji Nagashima, Masahiro Yao, Masatoshi Eto, W Marston Linehan, Yuichi Oike, Tomomi Kamba
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] The Growth Cone phosphoproteomics reveals an Axonal Regeneration Marker2018

    • Author(s)
      Masayasu Okada, Asami Kawasaki, Atsushi Tamada, Yutaka Yoshida, Takeuchi Kosei, Yukihiko Fujii, Michihiro Igarashi.
    • Organizer
      Cold Spring Harbor Asia Conference in Awaji
    • Int'l Joint Research
  • [Presentation] The role of SET in Gastric Cancer2018

    • Author(s)
      Ohama T
    • Organizer
      Workshop on Frontiers in Phosphatase Research and Drug Discovery
    • Int'l Joint Research / Invited
  • [Presentation] Tumor-stromal interaction during bone metastasis2018

    • Author(s)
      Shingo Sato
    • Organizer
      8th Seoul Breast Cancer 2018
    • Int'l Joint Research / Invited
  • [Presentation] Unexpected motor and histopathological phenotype found in mice that lack SEPT7 in the cerebellum2018

    • Author(s)
      Sakakibara K, Fukumasu N, Ageta-Ishihara N, Fukazawa Y, Takao K, Miyakawa T, Bito H, Kinoshita M.
    • Organizer
      The 6th Neural Circuits Joint Workshop
  • [Presentation] アビカル膜へのスフィンゴミエリン輸送を制御する分子機構の解明2018

    • Author(s)
      小野由美子、池ノ内順一
    • Organizer
      平成30年度日本生化学会九州支部例会
  • [Presentation] がんのエネルギー代謝-がん悪性形質との関連2018

    • Author(s)
      國安弘基、森汐莉、谷里奈、岸真吾、西口由希子、森拓也、宮川良博、後藤桂、川原勲、大森斉
    • Organizer
      第29回日本消化器癌発生学会、シンポジウム : がんメタポロームーマルチオミクスによる複雑性の統一
    • Invited
  • [Presentation] がん抑制遺伝子p19Arfに存在する非同義置換多型における機能解析2018

    • Author(s)
      斎藤慈、奥村和弘、磯貝恵理子、若林雄一
    • Organizer
      第27回日本癌病態治療研究会
  • [Presentation] がん抑制遺伝子p19Arfに存在する非同義置換多型の機能解析2018

    • Author(s)
      斎藤慈、奥村和弘、磯貝恵理子、若林雄一
    • Organizer
      第65回実験動物学会総会
  • [Presentation] がん抑制遺伝子p19Arfに存在する非同義置換多型の腫瘍悪性化における役割2018

    • Author(s)
      斎藤慈
    • Organizer
      第31回モロシヌス研究会
  • [Presentation] がん細胞が分泌するマイクロRNAが造骨型/溶骨型骨転移を誘導する2018

    • Author(s)
      佐藤信吾
    • Organizer
      第265回関東骨軟部腫瘍研究会
    • Invited
  • [Presentation] がん抑制遺伝子p19Arf に存在する非同義置換多型の腫瘍悪性化における役2018

    • Author(s)
      齋藤 慈
    • Organizer
      第31回モロシヌス研究会
  • [Presentation] グルタミン代謝の生活習慣病と癌における役割とその分子病態2018

    • Author(s)
      鈴木佐和子
    • Organizer
      第18回TCカンファランス
  • [Presentation] ゲノム編集で作製したグルタミン酸脱炭酸酵素ノックアウトラットの表現型2018

    • Author(s)
      柳川右千夫、藤原和之、柿崎利和、宮田茂雄、渡辺雅彦、大城朝一、虫明元、宮坂佳樹、真下知士
    • Organizer
      日本ゲノム編集学会第3回大会
  • [Presentation] ケミカルゲノミクスによるオートファジー制御機構の解析2018

    • Author(s)
      片浦哲志
    • Organizer
      第29回新薬創製談話会
  • [Presentation] 小細胞肺がんの悪性化における細胞接着分子CADM1の機能解析2018

    • Author(s)
      舩城桐子、伊東剛、村上善則
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] ストレス応答性翻訳制御因子NFAR2の天然変性領域欠損マウスの網羅的行動解析2018

    • Author(s)
      山下映、藤井一希、腰高由美恵、安達真由美、笹川恵理、中川真一、高雄啓三、椎名伸之
    • Organizer
      第41回日本分子生物学会
  • [Presentation] 自然免疫制御に関わる新規RING型E3(RNF126)の同定と機能解析2018

    • Author(s)
      阿部貴則、及川大輔、寺脇正剛、後藤栄治、高橋宏隆、大竹史明、川原裕之、堀居拓郎、畑田出穂、佐伯泰、田中啓二、澤崎達也、徳永文稔
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 阻害剤ライブラリーを用いたKLF4によるMMP13発現誘導メカニズムの解析2018

    • Author(s)
      鬼頭昭吉、竹内優斗、阿部真土
    • Organizer
      第11回大阪大学医学系若手フォーラム
  • [Presentation] ドーパミン受容体及びNMDA受容体変異マウスを用いた大脳基底核回路の機能解析2018

    • Author(s)
      笹岡 俊邦, 佐藤 朝子, 知見 聡美, 大久保 直, 齊藤 奈英, 福田七穂, 内山 澄香, 作間 赳法, 阿部 光寿, 田中 稔, 山本 美丘, 三浦詩織, 阿部 学, 川村 名子, 小田 佳奈子, 佐藤 俊哉, 岡本浩嗣, 藤澤 信義, 田井中一貴, 崎村 建司, 南部 篤
    • Organizer
      科学研究費補助金「新学術領域研究(研究領域提案型)」非線形発振現象を基盤としたヒューマンネイチャーの理解「オシロロジー」2018年度第1回領域会議
  • [Presentation] トポイソメラーゼ阻害薬lamellarinの化学修飾による耐性EGFR T790M/C797S阻害薬の創製2018

    • Author(s)
      西谷直之、奥裕介、福田勉、旦慎吾、石橋郁人、矢守隆夫、上原至雅、岩尾正倫
    • Organizer
      第22回日本がん分子標的治療学会学術集会
  • [Presentation] トレハロースと類縁体化合物の神経変性疾患治療薬としての可能性2018

    • Author(s)
      和田俊一
    • Organizer
      第22回トレハロースシンポジウム
    • Invited
  • [Presentation] パーキンソン病バイオマーカーを指標とする新規治療薬シードの探索2018

    • Author(s)
      片浦哲志, 井本正哉
    • Organizer
      第9回スクリーニング学研究会
  • [Presentation] バイオマーカーを指標とするパーキンソン病治療薬の探索とBET阻害剤JQIによる神経保護活性2018

    • Author(s)
      片浦哲志, 斉木臣二, 服部信孝, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第13年会
  • [Presentation] パルミトイルピペリジノピペリジンの抗がん効果発現機序2018

    • Author(s)
      安藤さえこ、松本晴年、深町勝巳、二口充、酒々井眞澄
    • Organizer
      第25回日本がん予防学会総会
  • [Presentation] 皮膚早期腫瘍抵抗性遺伝子座Stmmlaの原因遺伝子の同定2018

    • Author(s)
      奥村和弘、斎藤慈、磯貝恵理子、荒木喜美、若林雄一
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] マウス胎児被曝による脳の組織障害と認知機能への影響2018

    • Author(s)
      高井 伸彦、大神 正次
    • Organizer
      第55回放射線影響懇話会
  • [Presentation] ミトコンドリアオートファジー : 分子機構と生理的意義2018

    • Author(s)
      神吉智丈
    • Organizer
      Advans研究会2018
    • Invited
  • [Presentation] 潜性遺伝形式を示す自然発生突然変異多血症モデルマウス『pocy』の解析2018

    • Author(s)
      北元優梨、古閑成美、林田隆成、慶田貴子、吉信公美子、柳久美子、要匡、荒木喜美、荒木正健
    • Organizer
      第31回モロシヌス研究会
  • [Presentation] 劣性(潜性)遺伝形式を示す自然発生t血症モデルマウス『pocy』の解析2018

    • Author(s)
      北元優梨、古閑成美、林田隆成、慶田貴子、吉信公美子、柳久美子、要匡、荒木喜美、荒木正健
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 劣性(潜性)遺伝形式を示す自然発生多血症モデルマウス『pocy』の解析2018

    • Author(s)
      荒木正健、古閑成美、林田隆成、北元優梨、慶田貴子、吉信公美子、柳久美子、要匡、荒木喜美
    • Organizer
      第65回日本実験動物学会総会
  • [Presentation] 悪性がんのバイオマーカーとしてのラミニンγ2単鎖2018

    • Author(s)
      越川直彦
    • Organizer
      第27回日本がん転移学会学術集会会長講演
    • Invited
  • [Presentation] 胃癌におけるRegⅣ及びMCOLN3の化学療法治療効果予測因子としての有用性2018

    • Author(s)
      西口由希子、谷 里奈、笹平智則、庄 雅之、國安弘基
    • Organizer
      第118回日本外科学会
  • [Presentation] 塩の摂り過ぎで生じる全身の異常2018

    • Author(s)
      西山 成
    • Organizer
      第39回日本妊娠高血圧学会学術集会
    • Invited
  • [Presentation] 海洋天然物ラメラリンNの構造改変によるT790M/C797S耐性変異EGFRに有効な可逆型チロシンキナーゼ阻害剤の開発2018

    • Author(s)
      福田勉、石橋郁人、奥裕介、西谷直之、旦慎吾、矢守隆夫、上原至雅、岩尾正倫
    • Organizer
      第36回メディシナルケミストリーシンポジウム
  • [Presentation] 核小体ストレス応答による分裂期監視と癌治療戦略2018

    • Author(s)
      河原康一、川畑拓斗、古川龍彦
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 核小体を標的としたp53活性化機構による新たな癌治療2018

    • Author(s)
      河原康一、古川龍彦
    • Organizer
      第22回日本がん分子標的治療学会学術集会
  • [Presentation] 核小体再編成により細胞分裂を監視する新たなオルガネラストレス応答2018

    • Author(s)
      河原 康一、古川 龍彦
    • Organizer
      第91回日本生化学会大会
  • [Presentation] 環境温度変化に応答した脂肪組織におけるミトコンドリア分解2018

    • Author(s)
      神吉智丈
    • Organizer
      BIOTHERMOLOGY WORKSHOP
    • Invited
  • [Presentation] 癌抑制因子p53を制御する機構の解明と新たな癌治療戦略2018

    • Author(s)
      河原康一
    • Organizer
      JSBi九州地域部会セミナー
    • Invited
  • [Presentation] 空間弁別の分子・細胞学的基盤 -個性の階層的理解を目指して-2018

    • Author(s)
      上田(石原)奈津実
    • Organizer
      次世代脳冬のシンポジウム4領域合同若手シンポジウム
    • Invited
  • [Presentation] 減数分裂の開始機構と染色体構築2018

    • Author(s)
      石黒啓一郎
    • Organizer
      第63回日本生殖医学会学術講演会
    • Invited
  • [Presentation] 光による脳・神経系の時空間パターニング2018

    • Author(s)
      八尾 寛
    • Organizer
      第19回山形ニューロサイエンス・医工学研究会
    • Invited
  • [Presentation] 抗 claudin-4 抗体のがん治療への応用2018

    • Author(s)
      國安弘基、西口由希子、谷 里奈、岸 真五、近藤昌夫
    • Organizer
      第107回日本病理学会総会、ワークショップ : 多機能な細胞接着分子が関わるがんの理解-診断・治療への応用をめざして
    • Invited
  • [Presentation] 抗腫瘍性Aplysiatoxin単純化アナログ・10-Me-Aplog-1のアセタール型アナログの合成と生物活性2018

    • Author(s)
      早川皓太郎、花木祐輔、徳田春邦、柳田 亮、中川 優、入江一浩
    • Organizer
      第60回天然有機化合物討論会
  • [Presentation] 心不全における過剰なインスリンシグナルの意義2018

    • Author(s)
      清水 逸平
    • Organizer
      心臓病学会
  • [Presentation] 新生仔豚仮死モデルにおける水素ガス吸入療法による神経学的予後改善効果について.2018

    • Author(s)
      中村信嗣、インモン トゥン、日下隆, 他
    • Organizer
      第8回日本分子状水素医学生物学会大会
  • [Presentation] 新生児蘇生中の脳循環モニタリングによる脳障害重症度判定法 ~時間分解分光装置を用いた新生仔豚仮死モデル実験~2018

    • Author(s)
      光家努、日下隆, 他
    • Organizer
      第21回日本光機能イメージング学会学術集会
  • [Presentation] 成熟膵島で抑制されている遺伝子の解析2018

    • Author(s)
      西村 渉, 安田 和基, 松本征仁, 岡崎康司, 野田泰子
    • Organizer
      第61回日本糖尿病学会
  • [Presentation] 成長円錐リン酸化プロテオミクスにより神経成長のシグナル伝達2018

    • Author(s)
      河嵜 麻実
    • Organizer
      第91回日本生化学大会
  • [Presentation] 生合成経路の再構築と再設計による糸状菌ジテルペノイドピロンライブラリーの構築と生物活性評価2018

    • Author(s)
      塚田健人, 金子秋穂, 新木翔之, 河治久実, 児玉栄一, 倉石貴透, 村上一馬, 入江一浩, 平田尚也, 諫田泰成, 浅井禎吾
    • Organizer
      第18回メディシナルケミストリーシンポジウム
  • [Presentation] 生殖細胞の減数分裂開始を決定する新規因子2018

    • Author(s)
      石黒啓一郎
    • Organizer
      湯島性分化勉強会2018
    • Invited
  • [Presentation] 長鎖非翻訳RNAを標的としたがん治療薬の開発2018

    • Author(s)
      勝島啓佑、夏目敦至、大岡史治、新城恵子、柴田龍弘、宮田完二郎、片岡一則、近藤豊
    • Organizer
      第77回日本癌学会学術総会
    • Invited
  • [Presentation] 転移巣にTAMを呼び寄せるメカニズムとそれを阻害する既存薬2018

    • Author(s)
      中山 敬一
    • Organizer
      第16回がんとハイポキシア研究会
    • Invited
  • [Presentation] 脳におけるグルタミン酸脱炭酸酵素アイソフォームの役割 : ノックアウトマウスとノックアウトラットの表現型の比較研究2018

    • Author(s)
      柳川右千夫
    • Organizer
      第41回日本分子生物学会年会
    • Invited
  • [Presentation] 肺がんにおける分子標的薬耐性機構解析と耐性克服法予測の可能性2018

    • Author(s)
      片山 量平、藤田 直也
    • Organizer
      第77回 日本癌学会学術総会
    • Invited
  • [Presentation] 肺がん分子標的薬耐性メカニズムの探索と耐性機構予測への挑戦2018

    • Author(s)
      片山 量平、岡田 康太郎、藤田 直也
    • Organizer
      第22回 日本がん分子標的治療学会学術総会
    • Invited
  • [Presentation] 肺癌の神経内分泌性格を制御する分子機構の解析2018

    • Author(s)
      末永 雄介、新行内 雅斗、兼松 宗太郎、飯笹 俊彦、加藤 護、横井 左奈
    • Organizer
      第27回日本癌病態治療研究会
  • [Presentation] 尾動脈注射手法を用いたLuminal乳がん骨高転移株とその遺伝子発現解析2018

    • Author(s)
      Yuxuan Han、中山淳、二口充、仙波憲太郎
    • Organizer
      第27回日本がん転移学会学術集会・総会
  • [Presentation] 腹側被蓋野(VTA)のGABA作動性神経はノンレム睡眠を調節する2018

    • Author(s)
      山中章弘
    • Organizer
      平成30年度脳研究所共同利用共同研究合同セミナー
    • Invited
  • [Presentation] 分裂期核小体の再編成によって制御される分裂期監視機構と腫瘍化制御2018

    • Author(s)
      河原康一、川畑拓斗、朝日汰一、古川龍彦
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 老化・癌化におけるメタポライトと解糖系代謝研究2018

    • Author(s)
      近藤祥司
    • Organizer
      第60回日本老年医学会
    • Invited
  • [Presentation] Involvement of Pol β in postnatal neuronal development and function via active DNA demethylation2018

    • Author(s)
      Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto and Noriyuki Sugo
    • Organizer
      国立遺伝学研究所研究会「哺乳類脳の機能的神経回路の構築メカニズム」
  • [Presentation] 腸管センシングの可視化解析2018

    • Author(s)
      安達貴弘
    • Organizer
      第8回オルソオルガノジェネシス検討会
  • [Presentation] ZO family proteins regulate epithelial polarity independent of Tight Junction strand assembly2018

    • Author(s)
      Tetsuhisa Otani, Shinsaku Tokuda, and Mikio Furuse
    • Organizer
      第70回日本細胞生物学会大会・第51回日本発生生物学会大会合同大会
  • [Presentation] ZO family proteins regulate epithelial polarity independent of Tight Junction strand assembly2018

    • Author(s)
      Tetsuhisa Otani, Shinsaku Tokuda, and Mikio Furuse
    • Organizer
      ASCB EMBO 2018 meeting
    • Int'l Joint Research
  • [Presentation] Attenuation of Synaptic Potentials in Dendritc Spines2018

    • Author(s)
      Sakamoto M, Kwon T, Peterka DS, Yuste R.
    • Organizer
      Research PlaNet 2018
    • Invited
  • [Presentation] Attenuation of Synaptic Potentials in Dendritc Spines2018

    • Author(s)
      Sakamoto M, Kwon T, Peterka DS, Yuste R.
    • Organizer
      第10回光操作研究会・第2回脳情報動態合同国際シンポジウム
    • Int'l Joint Research
  • [Presentation] Chemo-enzymatic Total Syntheses of Tetrahydroisoquinoline Alkaloids2018

    • Author(s)
      Ryo Tanifuji
    • Organizer
      Otsu Conference 2018
  • [Presentation] Chemo-enzymatic Total Syntheses of Tetrahydroisoquinoline Alkaloids2018

    • Author(s)
      Hiroki Oguri
    • Organizer
      The 3rd A3 Roundtable Meeting on Chemical Probe Research Hub
    • Int'l Joint Research / Invited
  • [Presentation] Design and Modular De Novo Synthesis of 6-Aza-artemisinins2018

    • Author(s)
      高橋紀人
    • Organizer
      JSPS日中韓フォーサイト事業「A3アジア化学プロープ研究拠点事業若手研究者ミーティング」
  • [Presentation] Design and Modular De Novo Synthesis of 6-Aza-artemisinins2018

    • Author(s)
      Norihito Takahashi, Bonepally Karunakar Reddy, Naoya Matsuoka, Hiroki Oguri
    • Organizer
      The Third A3 Roundtable Meeting on Chemical Probe Research Hub
    • Int'l Joint Research
  • [Presentation] Ferroptosis in cancer research.2018

    • Author(s)
      Toyokuni S.
    • Organizer
      The 10th Internaitonal Coference on Heme Oxygenase 2018
    • Int'l Joint Research / Invited
  • [Presentation] Ferroptosis in cancer research.2018

    • Author(s)
      Toyokuni S.
    • Organizer
      Cold Spring Harbor Conferences Asia : Iron, Reactive Oxygen Species & Ferroptosis.
    • Int'l Joint Research / Invited
  • [Presentation] Phospholipase C β3 mediates climbing fiber synapse elimination in aldolase C-positive compartments of the developing mouse cerebellum2018

    • Author(s)
      渡邉貴樹, 賴友梨恵, 狩野方伸
    • Organizer
      The 75th Fujihara Seminar
  • [Presentation] Phospholipase C β3 mediates climbing fiber synapse elimination in aldolase C-positive compartments of the developing mouse cerebellum2018

    • Author(s)
      渡邉貴樹, 賴友梨恵, 狩野方伸
    • Organizer
      次世代脳プロジェクト冬のシンポジウム2018
  • [Presentation] T細胞受容体を介したNF-кBシグナル制御の数理シミュレーション2018

    • Author(s)
      後藤栄治、濱田大輔、及川大輔、鈴木貴、徳永文稔
    • Organizer
      第91回日本生化学会大会
    • Invited
  • [Presentation] 上皮バリアと上皮極性形成における密着結合の役割2018

    • Author(s)
      大谷哲久、徳田深作、古瀬幹夫
    • Organizer
      第8回生理研・名古屋大学医学部合同シンポジウム
  • [Presentation] 上皮バリアと上皮極性形成における密着結合の役割2018

    • Author(s)
      大谷哲久、古瀬幹夫
    • Organizer
      生理学研究所研究会「体内環境の維持機構における上皮膜輸送の多角的・統合的理解」
  • [Presentation] 睡眠と記憶を制御する神経活動の操作と記録2018

    • Author(s)
      山中章弘
    • Organizer
      第8回生理学研究所・名古屋大学医学系研究科合同シンポジウム
    • Invited
  • [Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節2018

    • Author(s)
      伊藤志帆, 杉田愛, 石黒尋保, 田渕圭章, 大熊芳明, 廣瀬豊
    • Organizer
      第20回日本RNA学会年会
  • [Presentation] リン酸化CTD結合因子PCIF1による遺伝子発現調節2018

    • Author(s)
      伊藤志帆, 杉田愛, 柳澤奈月, 石黒尋保, 佐藤崇之, 田渕圭章, 大熊芳明, 廣瀬豊
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 自然免疫制御に関わる新規脱ユビキチン化酵素(OTUD1)の同定と生理機能解析2018

    • Author(s)
      駒倉啓大、後藤栄治、及川大輔、阿部貴則、徳永文稔
    • Organizer
      第13回臨床ストレス応答学会
  • [Presentation] 新規LUBAC阻害剤の探索と機能評価2018

    • Author(s)
      及川大輔、花田和希、勝矢健、菅原弘二、水上裕加里、鶴田大輔、坂本信二、徳永文稔
    • Organizer
      第41回日本分子生物学会
  • [Presentation] 睡眠と記憶を制御する神経活動の操作と記録2018

    • Author(s)
      山中章弘
    • Organizer
      星薬科大学セミナー
    • Invited
  • [Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018

    • Author(s)
      安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
    • Organizer
      日本ケミカルバイオロジー学会 第13回年会
  • [Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018

    • Author(s)
      安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
    • Organizer
      第13回 化学生態学研究会
  • [Presentation] 直鎖状ユビキチン鎖生成酵素(LUBAC)に対する新規阻害剤の開発と炎症病態抑制2018

    • Author(s)
      及川大輔、花田和希、勝矢健、菅原弘二、水上裕加里、鶴田大輔、坂本信二、徳永文稔
    • Organizer
      第13回臨床ストレス応答学会
  • [Presentation] 膜電位感受性蛍光プローブを用いた神経活動イメージング2018

    • Author(s)
      坂本雅行
    • Organizer
      生命科学セミナー
    • Invited
  • [Presentation] Development of Red-Shifted Channelrhodopsin Variants Using Long-Conjugated Retinal Analogues.2018

    • Author(s)
      Yi-Chung Shen, Toshikazu Sasaki, Take Matsuyama, Takahiro Yamashita, Yoshinori Shichida, Takashi Okitsu, Yumiko Yamano, Akimori Wada, Toru Ishizuka, Hiromu Yawo, Yasushi Imamoto.
    • Organizer
      18th International Conference on Retinal Proteins
    • Int'l Joint Research
  • [Presentation] ヒト小細胞肺癌の自然転移モデルを活用した転移関与因子の同定2018

    • Author(s)
      坂本修一、川田学
    • Organizer
      第27回日本がん転移学会学術集会・総会
  • [Presentation] 255症例の悪性胸膜中皮腫の網 羅的遺伝子解析2018

    • Author(s)
      竹下 純平、辰野 健二、松本 大地、栗林 康造、近藤 展行、長谷川 誠紀、佐藤 鮎子、辻村 亨、大多 茂樹、河上 裕、中野 孝司、油谷 浩幸
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 3-アルキニル1H-ピロール-2-カルボキシラートのヨウ素を用いた環化を経由するビラノ[3, 4-b]ピロールー7(1H)-オンの合成2018

    • Author(s)
      小牟禮稔、福田勉、小野寺玄、木村正成
    • Organizer
      第21回ヨウ素学会シンポジウム
  • [Presentation] 6-アザーアルテミシニン群の設計とモジュラ一式迅速合成プロセスの開発2018

    • Author(s)
      高橋紀人、Bonepally Karunakar Reddy、松岡直弥、岩月正人、石山亜紀、穂苅玲、乙黒一彦、大村智、大栗博毅
    • Organizer
      第60回天然有機化合物討論会
  • [Presentation] A novel treatment and preventive method for Down syndrome-related acute megakayoblastic leukemia2018

    • Author(s)
      大里元美
    • Organizer
      第41回日本分子生物学会
    • Invited
  • [Presentation] A translation inhibitor targets a bimolecular cavity between eIF4A and polypurine RNA2018

    • Author(s)
      岩崎信太郎
    • Organizer
      International Symposium on “Proteins ; from the Cradle to the Grave”
  • [Presentation] Aberration of the Soluble protein Tsukushi leads altera-(P3-071) tion of adult neurogenesis resulting lateral ventriculeexpansion with neuronal disease.2018

    • Author(s)
      Naofumi Ito, M. Asrafuzzaman Riyadh, Ayako Ito, Shah Adil Ishtiyaq, Mohamad Badrul Anam, Yonehiro Kanemura Yohei Shinmyo, Athary Felemban, Jun Hatakeyama, Hiroshi Kiyonari, Kenji Shimamura, Yoshiko Takahashi, Kazunobu, Sawamoto and Kunimasa Ohta
    • Organizer
      第70回日本細胞生物学会・第51回日本発生生物学会合同大会学会
  • [Presentation] Action polymerization factor Fhod3 formin protein in the mouse cerebrocortical neurons2018

    • Author(s)
      Takayuki Nemoto, Hikmawan Wahyu Sulistomo, Ryu Takeya
    • Organizer
      第18回国際薬理学会
    • Int'l Joint Research
  • [Presentation] Application of Genetics to Epilepsy after Gene-Hunting2018

    • Author(s)
      Hirose S
    • Organizer
      ANZCNS 7th Annual Scientific Meeting
    • Int'l Joint Research
  • [Presentation] BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of mutations in chromatin remodeling genes2018

    • Author(s)
      Ryosuke Jikuya, Mitsuko Furuya, Masaya Baba, Hiroyuki Aburatani, Adam R Metwalli, Laura S Schmidt, W Marston Linehan, Masahiro Yao, Hisashi Hasumi
    • Organizer
      AACR Annual Meeting 2018
    • Int'l Joint Research
  • [Presentation] Bridging the gap in child health services : Japan experience2018

    • Author(s)
      Hirose S
    • Organizer
      18th Myanmar Pediatric and Allied Medical Specialties Conference
    • Int'l Joint Research
  • [Presentation] C2対称型中分子アルカロイド骨格を活用する機能性分子の創製2018

    • Author(s)
      大栗博毅
    • Organizer
      新学術領域研究「反応集積化が導く中分子戦略 : 高次生物機能分子の創製」第6回公開成果報告会
    • Invited
  • [Presentation] Cardio- and reno-protective effect of dipeptidyl peptidase Ⅲ.2018

    • Author(s)
      扇田久和、Xiaoling Pang、清水昭男
    • Organizer
      American Heart Association Scientific Sessions 2018
    • Int'l Joint Research
  • [Presentation] Central thermoregulatory circuits to defend homeostasis from environmental stressors2018

    • Author(s)
      Nakamura, K.
    • Organizer
      Mini-Symposium on Temperature and Metabolism
    • Int'l Joint Research / Invited
  • [Presentation] Challenges and Opportunities in Pediatric Neurological Disease in Low Income Countries like Nepal2018

    • Author(s)
      Hirose S
    • Organizer
      XIXtb Nepalese Congress of Paediatrics, NEPCON 2018 & 37th Anniversary NEPAS (Nepal Paediatric Society) Nepcon-2018
    • Int'l Joint Research
  • [Presentation] Chemo-enzymatic Total Syntheses of Saframycins and Jorunnamycins2018

    • Author(s)
      Hiroki Oguri
    • Organizer
      The 18th Tateshina Conference on organic Chemistry
    • Invited
  • [Presentation] Clinicopathological Analyses of 17 Cases of XpllTranslocation Renal Cell Carcinomas2018

    • Author(s)
      Mitsuko Furuya, Masaya Baba, Ikuma Kato, Tsunenori Kondo, Yoji Nagashima, Takao Kamai, Toshinari Yamasaki, Osamu Ogawa, Koushiro Nishimoto, Msafumi Koyama, Tomomi Kamba, Takanobu Motoshima, Masatoshi Eto
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.2018

    • Author(s)
      Ryota Sato, Akihisa Kato, Takahiko Chimura, Shin-Ichiroh Saitoh, Takuma Shibata, Yusuke Murakami, Ryutaro, Fukui, Kaiwen Liu, Yun Zhang, Jun Arii, Ge-Hong Sun-Wada, Yoh Wada, Tsuneo Ikenoue, Glen N Barber, Toshiya Manabe, Yasushi Kawaguchi, Kensuke Miyake
    • Organizer
      日本免疫学会
  • [Presentation] Comprehensive identification of wound healing and inflammation miRNAs reveals a key role for miR-223 in neutrophilic clearance of S. aureus at wound sites2018

    • Author(s)
      森亮一
    • Organizer
      EMBL Symposia The Complex Life of RNA
    • Int'l Joint Research
  • [Presentation] Comprehensive molecular charatcterization of malignant pleural mesothelioma2018

    • Author(s)
      Takeshita J, Yamamoto S, Tatsuno K, Shiraishi Y, Kuribayashi K, Kondo N, Hasegawa S, Sato A, Tsujimura T, Matsumoto D, Ohta S, Kawakami Y, Nakano T, Sekido Y, Aburatani H.
    • Organizer
      第16回日本臨床腫瘍学会学術集会
  • [Presentation] Deficiency of AMPA receptor-palmitoylation aggravates the seizure susceptibility2018

    • Author(s)
      Masayuki Itoh, Mariko Yamashita, Masaki Kaneko, Hiroyuki Okuno, Manabu Abe, Maya Yamazaki, Rie Natsume, Daisuke Yamada, Toshie Kaizuka, Reiko Suwa, Kenji Sakimura, Masayuki Sekiguchi, Keiji Wada, Mikio Hoshino, Masayoshi Mishina, Takashi Hayashi
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] Department of Neurochemistry and Molecular Cell Biology2018

    • Author(s)
      五十嵐 道弘
    • Organizer
      第61回日本神経化学会大会
    • Invited
  • [Presentation] Design and Synthesis of DNA Alkylationg Natural Products : A Chemo-enzymatic Approach2018

    • Author(s)
      Hiroki Oguri
    • Organizer
      International Syntheposis on Biosensing for Next Generation ; Design and Development of Molecular Recognition Element, TUAT GIR International Symposium
    • Int'l Joint Research / Invited
  • [Presentation] Development of linear hexaoxazoles as topology as topology-selective G-quadruplex stabilizing ligandsv2018

    • Author(s)
      Shogo Sasaki, Yue Ma, Kazuo Nagasawa
    • Organizer
      BIONIC 2018
    • Int'l Joint Research
  • [Presentation] Development of Red-Shifted Channelrhodopsin Variants Using Long-Conjugated Retinal Analogues.2018

    • Author(s)
      Yi-Chung Shen, Toshikazu Sasaki, Takesi Matsuyama Hoyos, Takahiro Yamashita, Yoshinori Shichida, Takashi Okitsu, Yumiko Yamano, Akimori Wada, Toru Ishizuka, Hiromu Yawo, Yasushi Imamoto
    • Organizer
      生物物理学会第56回年会
  • [Presentation] Differential properties of dopamine D1 and D2-type medium spiny neuron via cortico-striatal stimulation in the beta frequency range.2018

    • Author(s)
      稲垣 良, 笹川 正人, 本間 経康, 小山内 実
    • Organizer
      次世代脳プロジェクト冬のシンポジウム
  • [Presentation] Differential roles of dopamine D1 and D2 receptor function in the primate caudate for decision making under aversive context2018

    • Author(s)
      Ueda Y, Yasuda M, Nakamura K
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Dissociating orexin-dependent and -independent functions of orexin neurons using novel orexin-Flp knck-in mice2018

    • Author(s)
      Yamanaka A
    • Organizer
      7th International Symposium on Narcolepsy
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of neuronal signals in primate midbrain dopamine neurons and orbitofrontal cortex neurons during value-to-decision transformation2018

    • Author(s)
      M. YUN, T. KAWAI, M, NEJIME, H. YAMADA, M. MATSUMOTO
    • Organizer
      2018年度北米神経科学大会
    • Int'l Joint Research
  • [Presentation] Effect of combination intake of glucose and lauric acid on tumor growth and skeletal muscle atrophy in CT26 mouse model2018

    • Author(s)
      Mori T, Miyagawa Y, Kawahara I, Goto K, Mori S, Kishi S, Fujiwara-Tani R, Kuniyasu H
    • Organizer
      77th Annual Meeting of Japanese Association for Cancer
  • [Presentation] EMP1 signaling promotes cancer invasiveness and metastasis.2018

    • Author(s)
      Mohammad Khusni Bin Ahmat Amin、清水昭男、Dimitar P. Zankov、佐藤朗、扇田久和
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Ensemble representation of contextual memory in hippocampal engram cells2018

    • Author(s)
      大川 宜昭、井ノ口 馨
    • Organizer
      第41回日本神経科学大会・シンポジウム : 最先端光イメージングによる深部脳観察へのアプローチ(Seeing the invisible : the art of deep brain imaging)
    • Invited
  • [Presentation] Evolution of palmitoylation sites of 5-HT (serotonin) receptors in vertebrates2018

    • Author(s)
      Takashi Hayashi
    • Organizer
      11th FENS Forum of Neuroscience
    • Int'l Joint Research
  • [Presentation] Expression of claudin 1 and 4 in renal cell carcinoma2018

    • Author(s)
      Owari T, Kishi S, Fujiwara-Tani R. Mori S, Miyake M, Nakai Y, Kondou M, Fujimoto H, Kuniyasu H
    • Organizer
      77th Annual Meeting of Japanese Association for Cancer
  • [Presentation] Expression of cytosolic malic enzyme (ME1) is associated with disease progression in human oral squamous cell carcinoma2018

    • Author(s)
      Nakashima C, Yamamoto K, Tani R, Bhawal UK, Sasahira T, Kirita T, Kuniyasu H
    • Organizer
      77th Annual Meeting of Japanese Association for Cancer
  • [Presentation] Ferroptosis in carcinogenesis and tumor biology.2018

    • Author(s)
      Toyokuni S.
    • Organizer
      19th Biennial meeting of the Society for Free Radical Research International.
    • Int'l Joint Research / Invited
  • [Presentation] Foxr2 promotes formation of CNS-embryonal tumors in a Trp53-deficient background2018

    • Author(s)
      高祖 秀登
    • Organizer
      19th International Congress of Neuropathology (ICN 2018)
    • Int'l Joint Research
  • [Presentation] Functional analysis of the kinase module of human Mediator complex using a Baculovirus-insect cell expression system2018

    • Author(s)
      Harako S, Hayasi H, Tanzawa M, Fujita C, Iida S, Tanaka A, Hirose Y, Ohkuma Y
    • Organizer
      The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network
    • Int'l Joint Research
  • [Presentation] Functional Relevance of cell competition in intestinal neoplasms2018

    • Author(s)
      昆 俊亮、中井 一貴、田中 伸也、藤田 恭之
    • Organizer
      第41回日本分子生物学会
    • Invited
  • [Presentation] Functional validation of macaque promoter in mouse brain2018

    • Author(s)
      Nagai Y, Nishitani S, Yasuda M, Ueda Y, Shirakawa H, Nagayasu K, Nakamura K, Kaneko S
    • Organizer
      第41回日本神経科学大会
  • [Presentation] Genes in Focal Epilepsy2018

    • Author(s)
      Hirose S
    • Organizer
      ANZCNS 7th Annual Scientific Meeting
    • Int'l Joint Research
  • [Presentation] Genetic background of developmental and epileptic encephalopathies2018

    • Author(s)
      Hirose S
    • Organizer
      KEC2018 23th Korean Epilepsy Congress
    • Int'l Joint Research
  • [Presentation] Genetic regulation of RUNX2 induce apoptotic cell death through regulating the expression of SOX2 in CRPC-NE cells2018

    • Author(s)
      Yuki Noguchi, Natsuki Wariishi, Shiina Iwai, Gengo Kashiwazaki, Junichi Taniguchi, Toshikazu Bando, Masaya Baba, Souichi Adachi, Hiroshi Sugiyama, Yasuhiko Kamikubo
    • Organizer
      AACR Annual Meeting 2018
    • Int'l Joint Research
  • [Presentation] Genetic, epidemiologic and clinicopathologic studies of Japanese patients with Birt-Hogg-Dube syndrome, 2018 update2018

    • Author(s)
      Yasuhiro Iribe, Masahiro Yao, Yoji Nagashima, Masaya Baba, Yukio Nakatani, Mitsuko Furuya
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] hermosensory afferent neural pathways for autonmous and behavioral thermoregulation2018

    • Author(s)
      Nakamura, K.
    • Organizer
      7th International Meeting of the Physiology and Pharmacology of Temperature Regulation
    • Int'l Joint Research / Invited
  • [Presentation] Hierarchical roles of mitochondrial PAPI and Zucchini in Bombyx germline piRNA biogenesis2018

    • Author(s)
      塩見 美喜子
    • Organizer
      CSHA/Chromation, Epigenetics & Transcription
    • Int'l Joint Research / Invited
  • [Presentation] hnRNP A/Bパリアントによる mRNA局在化の制御2018

    • Author(s)
      福田 七穂、石田 靖雅、福田 智行、笹岡 俊邦
    • Organizer
      第41回日本分子生物学会年会 ワークショップ 新たな機能が明らかになる RNA結合タンバク質の生物学一原
  • [Presentation] How does neurotransmission contribute to axon reorganization? - Intervention in axonal competition by sparse gene knockout.2018

    • Author(s)
      Teppei Kanaya, Ryo Egawa, Hiromu Yawo.
    • Organizer
      Cold Spring Harbor meeting : Neuronal Circuits
    • Int'l Joint Research
  • [Presentation] HPC-1/syntaxin 1A regulates the cortical signal propagation by affecting the GABAergic transmission.2018

    • Author(s)
      Osanai M, Matsumura A, Fujiwara T, Kikuta S, Yagi T. Akagawa K
    • Organizer
      11th FENS Forum of Neuroscience
    • Int'l Joint Research
  • [Presentation] In situ Click反応を基盤とする生細胞中でのG4の可視化2018

    • Author(s)
      安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
    • Organizer
      第36回 メディシナルケミストリーシンポジウム
  • [Presentation] Involvement of VGLL3 in TGF-beta-induced epithelial-to-mesenchymal transition.2018

    • Author(s)
      Yamaguchi. N., Takakura. Y., Sugino. A., Yamaguchi, N., and Takano, H.
    • Organizer
      第2回日本循環器学会基礎研究フォーラム
  • [Presentation] iPS細胞関連技術とヒト型疾患モデルマウスを用いた精神疾患の分子病態解析2018

    • Author(s)
      中澤敬信、橋本亮太、田熊一敞、橋本均
    • Organizer
      第28回日本臨床精神神経薬理学会 第48回日本神経精神薬理学会 合同年会
    • Invited
  • [Presentation] KLF4による骨芽細胞分化の抑制はヘッジホッグシグナルの活性化でレスキューできる2018

    • Author(s)
      鬼頭昭吉、阿部真土
    • Organizer
      第11回大阪大学医学系若手フォーラム
  • [Presentation] KLF4は一次絨毛におけるヘッジホッグシグナルを介して骨芽細胞の分化を抑制する2018

    • Author(s)
      竹内優斗、鬼頭昭吉、阿部真土
    • Organizer
      第36回日本骨代謝学会学術集会
  • [Presentation] KLF4はヘッジホッグシグナルの減弱を介して骨芽細胞分化を抑制する2018

    • Author(s)
      竹内優斗、鬼頭昭吉、阿部真土、脇坂聡
    • Organizer
      第126回大阪大学歯学会
  • [Presentation] Latching mechanisms to generate ultrafast movement of the trap jaw in the ant Odontomachus kuroiwae2018

    • Author(s)
      H. Aonuma, K. Naniwa, K. Kagaya and K. Osuka
    • Organizer
      International Congress for Neuroethology
    • Int'l Joint Research
  • [Presentation] Lineage-specific RUNX2 super-enhancer activates MYC via translocation (6 ; 8) to promote the development of blastic plasmacytoid dendritic cell neoplasm2018

    • Author(s)
      Kubota S, Tokunaga K, Umezu T, Yokomizo T, Oshima M, Iwanaga E, Asou N, Iwama A, Ohyashiki K, Osato M, Sashida G.
    • Organizer
      60th ASH Annual Meeting-American Society of Hematology
    • Int'l Joint Research
  • [Presentation] Metabolic Control of Cancer Stemness2018

    • Author(s)
      平尾敦
    • Organizer
      The 2nd NanoLSI Symposium in London Towards Establishment of New Research Field : Nanoprobe Life Science-
    • Int'l Joint Research / Invited
  • [Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2018

    • Author(s)
      平尾敦
    • Organizer
      International symposium on drug discovery
    • Int'l Joint Research / Invited
  • [Presentation] miR-223 発現抑制は皮膚創傷部位の感染予防に効果的である2018

    • Author(s)
      森亮一
    • Organizer
      第8回臨床ゲノム医療学会
  • [Presentation] miR-27bに制御されるCSF1 による腎癌組織マクロファージの浸潤2018

    • Author(s)
      松本 大地, 田中 敬祐, 新井 恵吏, 金井 弥栄, 大多 茂樹, 河上 裕
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Molecular Characteristics of Renal Cell Carcinomas in Patients with Birt-Hogg-Dube Syndrome2018

    • Author(s)
      Mitsuko Furuya, Hasumi Hisashi, Ikuma Kato, Masaya Baba, Yoji Nagashima, Yasuhiro Iribe, Yukio Nakatani, Masahiro Yao
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] MPTPによるin vivoドーパミン生合成の低下はピオプテリン添加により回復する2018

    • Author(s)
      一瀬宏, 黒崎宏貴, 山口健太郎, 萬好晃平, 原怜
    • Organizer
      第22回活性アミンに関するワークショップ
  • [Presentation] Neural activity manipulation and behavior control by using fiber-less optogenetics2018

    • Author(s)
      Yamanaka A
    • Organizer
      National University of Singapore, Department of Chemistry, Research Seminar
    • Int'l Joint Research / Invited
  • [Presentation] Neural representation for right and left limb movements in rodent cerebral cortex2018

    • Author(s)
      Yoshikazu Isomura
    • Organizer
      The 8th CIN-NIPS Joint Symposium
    • Int'l Joint Research / Invited
  • [Presentation] New relationships between F-actin organization and memberance in the growth cone revealed by SIM2018

    • Author(s)
      野住 素広
    • Organizer
      Society for neuroscience
    • Int'l Joint Research / Invited
  • [Presentation] NFkB inhibitors as a novel therapeutic agent in the acute phase of Kawasaki disease2018

    • Author(s)
      Yoshikane Y, Koga M, Bhatnagar R, Cho T, Haraoka S, Hashimoto J, Miyamoto T, Hirose S, Ogawa A
    • Organizer
      American Heart Association Scientific Sessions 2018
  • [Presentation] NOTCH mutation in AML M72018

    • Author(s)
      大里元美
    • Organizer
      Singapore Society of Haematology and Targeted Therapy for Blood Cancer
    • Int'l Joint Research / Invited
  • [Presentation] Novel therapeutic role for dipeptidyl peptidase Ⅲ in the treatment of diabetic nephropathy.2018

    • Author(s)
      Xiaoling Pang、清水昭男、Dimitar P. Zankov、佐藤朗、石田哲夫、扇田久和
    • Organizer
      第91回日本生化学会大会
  • [Presentation] NRPSを活用した化学一酵素ハイプリッド合成を目指して2018

    • Author(s)
      大栗博毅
    • Organizer
      新学術領域研究「生合成リデザイン」第2回若手シンポジウム
    • Invited
  • [Presentation] Orexin and MCH neurons double ablation mice. Isolation of effect of orexin using orexin-Flippase mice.2018

    • Author(s)
      Yamanaka A
    • Organizer
      7th International Symposium on Narcolepsy
    • Int'l Joint Research / Invited
  • [Presentation] OTUD1は自然免疫制御に関わる脱ユピキチン化酵素である2018

    • Author(s)
      駒倉啓大、後藤栄治、及川大輔、阿部貴則、徳永文稔
    • Organizer
      第41回日本分子生物学会
  • [Presentation] Pathogenesis and genetic substrate2018

    • Author(s)
      Hirose S
    • Organizer
      19th International symposium on severe infantile epilepsies : old and new treatments
  • [Presentation] Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluAl C-terminal palmitoylation deficient mice2018

    • Author(s)
      Masayuki Itoh, Hiroyuki Okuno, Daisuke Yamada, Mariko Yamashita, Manabu Abe, Rie Natsume, Toshie Kaizuka, Kenji Sakimura, Mikio Hoshino, Masayoshi Mishina, Keiji Wada, Masayuki Sekiguchi, Takashi Hayashi
    • Organizer
      「次世代脳」 プロジェクト 冬のシンポジウム
  • [Presentation] piRNA biogenesis and function2018

    • Author(s)
      塩見 美喜子
    • Organizer
      CSHL/Regulatory & Non-coding RNA
    • Int'l Joint Research / Invited
  • [Presentation] Predicting non-responders to the steroid combination therapy in very severe Kawasaki disease2018

    • Author(s)
      Yoshikane Y, Hashimoto J, Miyamaoto T, Hirose S, Ogawa A
    • Organizer
      12th Interrnational Kawasaki Disease Symposium
    • Int'l Joint Research
  • [Presentation] Protective role of intercalated disk protein afadin in the pressure-overloaded heart.2018

    • Author(s)
      扇田久和
    • Organizer
      第2回日本循環器学会基礎研究フォーラム
    • Invited
  • [Presentation] Recognition of phospholipids on dead cells via inhibitory C-type lectin receptor.2018

    • Author(s)
      C. Motozono, T. Shimane, S. Torigoe, N. Nishimura, and S. Yamasaki.
    • Organizer
      第47回日本免疫学会学術集会
  • [Presentation] Regulation of sleep and memory2018

    • Author(s)
      山中章弘
    • Organizer
      Joint symposium of 10th Optogenetics Research Conference and Second International Symposium on Brain Information Dynamics 2018
    • Int'l Joint Research / Invited
  • [Presentation] Regulatory mechanism of sleep/wakefulness and memory by the hypothalamic neurons2018

    • Author(s)
      山中章弘
    • Organizer
      島根大学セミナー
    • Invited
  • [Presentation] Ribosome conformational dynamics surveyed by ribosome profiling2018

    • Author(s)
      岩崎信太郎
    • Organizer
      2nd JAJ (Joint Australia-Japan/Japan-Australia Joint) RNA Meeting
    • Int'l Joint Research
  • [Presentation] Role of C/EBP α-miR-223-Interleukin-6 secretion pathway at Staphylococcus aureus-infected wound sites2018

    • Author(s)
      森亮一
    • Organizer
      第41回日本基礎老化学会大会
  • [Presentation] Role of cholinergic neurons in the septum on the regulation of sleep and memory2018

    • Author(s)
      山中章弘
    • Organizer
      第41回日本神経科学大会 シンポジウム
    • Invited
  • [Presentation] Role of dopamine in the primate caudate for the decision making under different emotional context.2018

    • Author(s)
      Ueda Y, Yasuda M, Nakamura K
    • Organizer
      Neuroscience 2018
    • Int'l Joint Research
  • [Presentation] Role of Mammalian Formin Fhod3 in Neural Tube Closure2018

    • Author(s)
      Hikmawan W Sulistomo, Yohko Kage, Takayuki Nemoto, Ryu Takeya
    • Organizer
      第18回国際薬理学会
    • Int'l Joint Research
  • [Presentation] RUN-domainタンパク質Rufy3の役割2018

    • Author(s)
      本多 敦子
    • Organizer
      第59回新潟生化学懇話会
  • [Presentation] Selective Autophagy Regulates Lipid Metabolism2018

    • Author(s)
      小松雅明
    • Organizer
      Keystone Symposium
    • Int'l Joint Research / Invited
  • [Presentation] Selective Autophagy Regulates Lipid-oxidation2018

    • Author(s)
      小松雅明
    • Organizer
      24th IUBMB-15th FAOBMB Congress
    • Int'l Joint Research / Invited
  • [Presentation] Selective autophagy regulates lipid-oxidation through NCoRl-PPAR α-axis2018

    • Author(s)
      小松雅明
    • Organizer
      Cold Spring Harbor Asia meeting on Ubiquitin Family, Autophagy & Disease
    • Int'l Joint Research / Invited
  • [Presentation] Sleep/wakefulness analysis of orexin and MCH neurons double ablated mice2018

    • Author(s)
      Hung CJ, Ono D, Yamanaka A
    • Organizer
      7th International Symposium on Narcolepsy
    • Int'l Joint Research / Invited
  • [Presentation] Spontaneous development of intratumoral heterogeneity in a transposon-induced mouse model of glioma2018

    • Author(s)
      高祖 秀登
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Study of regulatory mechanism of sleep/wakefulness and memory by optogenetical neural activity manipulation2018

    • Author(s)
      山中章弘
    • Organizer
      第91回日本生化学会大会
    • Invited
  • [Presentation] Synaptopathies associated with loss of MDGAs2018

    • Author(s)
      Steven Connor, Ina Ammendrup-Johnsen, Yasushi Kishimoto, Parisa Karimi Tari, Vedrana Cvetkovska, Takashi Harada, Daiki Ojima, Tohru Yamamoto, Yu Tian Wang, Ann Marie Craig
    • Organizer
      17th Annual Molecular and Cellular Cognition Society Meeting
    • Int'l Joint Research
  • [Presentation] Targeting miR-223 in neutrophils enhances the clearance of S. aureus in infected wounds2018

    • Author(s)
      森亮一
    • Organizer
      東京理科大学トランスレーショナルリサーチセンター・ハワイ大学 合同シンポジウム
    • Int'l Joint Research
  • [Presentation] Taurine-modification of mitochondrial tRNA regulates proteostatic network and contribute to the quality of embryonic stem cells.2018

    • Author(s)
      魏 范研
    • Organizer
      lst International Mitochondria Meeting for Young Scientists
    • Int'l Joint Research / Invited
  • [Presentation] TEADの転写共役因子によるHippo経路活性化メカニズム解析.2018

    • Author(s)
      岡田和之, 高倉勇気, 竹洞裕貴, 堀 直人, 平井直人, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第17回 次世代を担う若手ファーマ・パイオフォーラム2018
  • [Presentation] TGF-betaにより発現誘導される転写共役因子VGLL3によるEMT制御機構の解析.2018

    • Author(s)
      山口憲孝.
    • Organizer
      第91回日本生化学会大会
    • Invited
  • [Presentation] The Dickkopfl-CKAP4 pathway, a novel cancer signaling, represents a therapeutic target for cancer therapy.2018

    • Author(s)
      Akira Kikuchi
    • Organizer
      IUBMB Congress 2018
    • Int'l Joint Research / Invited
  • [Presentation] The Dickkopfl-CKAP4 pathway, a novel cancer signaling, represents molecular targets for cancer therapy.2018

    • Author(s)
      Akira Kikuchi
    • Organizer
      第77回日本癌学会学術総会
    • Int'l Joint Research / Invited
  • [Presentation] The interaction analysis of a cyclic tetraoxazole with telomeric i-motif DNA2018

    • Author(s)
      Shadi Sedghi Masoud, Yudai Yamaoki, Yue Ma, Adrian Marchand, Fernaldo Richtia Winnerdy, Valerie Gabelica, Anh Tuan Phan, Masato Katahira, Kazuo Nagasawa
    • Organizer
      The 45rd International Symposium on Nucleic Acids Chemistry
    • Int'l Joint Research
  • [Presentation] The novel Dickkopfs-CKAP4 signaling pathway represents diagnostic and therapeutic targets for cancer.2018

    • Author(s)
      Akira Kikuchi
    • Organizer
      European Wnt Meeting2018
    • Int'l Joint Research / Invited
  • [Presentation] The serine protease TMPRSS2 plays a major role for in vivo replication of mouse parainfluenza viruses in a natural host.2018

    • Author(s)
      Kouji Sakai, Takashi Irie, Naoya Nagata, Yuriko Suzaki, Kazuaki Takehara, Yasushi Ami
    • Organizer
      第66回日本ウイルス学会学術集会
  • [Presentation] The serine protease TMPRSS2 plays a major role for in vivo replication of sendai virus in a natural host.2018

    • Author(s)
      Kouji Sakai, Takashi Irie, Naoya Nagata, Kazuaki Takehara, Yasushi Ami
    • Organizer
      The 17th Awaji International Forum on Infection and Immunity
    • Int'l Joint Research
  • [Presentation] TLR9 is a promising target for the neutralizing antibody in allergic airway inflammation2018

    • Author(s)
      村上祐輔、布川寛樹、三宅健介、山下直美
    • Organizer
      第47回日本免疫学会学術集会
  • [Presentation] Translational buffering upon splicing inhibition2018

    • Author(s)
      岩崎信太郎
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] tRNA modification in mitochondria disease2018

    • Author(s)
      魏 范研
    • Organizer
      15th Conference of the Asian Society of Mitochondrial Research and Medicine
    • Int'l Joint Research / Invited
  • [Presentation] Xp11.2転座型腎細胞癌で認めるキメラTFE3転写因子の機能解析2018

    • Author(s)
      馬場理也、元島崇信、馬 文娟、蓮見壽史、黄 榮、佐藤賢文、宮里パオラ、長嶋洋治、古屋充子、矢尾正祐、神波大己
    • Organizer
      第106回日本泌尿器科学会総会
  • [Presentation] X染色体不活化機構解明に向けた人工染色体の活用2018

    • Author(s)
      稲岡大悟, 大平崇人, 押村光雄, 中山祐二, 久郷裕之
    • Organizer
      第41回日本分子生物学会
  • [Presentation] ω3多価不飽和脂肪酸高含有餌摂取マウスにおける強制水泳試験無動時間の減少 : 腹側被蓋野-側坐核ドパミン神経系の関与2018

    • Author(s)
      竹内絵理、山田大輔、斎藤顕宜、伊藤政之、林崇、山田光彦、和田圭司、関口正幸
    • Organizer
      日本脂質栄養学会第27回大会
  • [Presentation] アクチン細胞骨格による樹状突起スパインの形態制御2018

    • Author(s)
      根本隆行、Hikmawan Wahyu Sulistomo、武谷 立
    • Organizer
      第71回日本薬理学会西南部会
  • [Presentation] アザラメラリンN誘導体のモジュール合成法の開発2018

    • Author(s)
      中野悠香、安在瑞穂、中原茜、山下健太朗、高翔、松倉一晃、福田勉、小野寺玄、木村正成、石橋郁人、岩尾正倫
    • Organizer
      第48回複素環化学討論会
  • [Presentation] アニリン型側鎖を有する大環状ヘキサオキサゾール化合物の合成とグアニン四重鎖の安定可能2018

    • Author(s)
      松田未沙子, 馬悦, 小林美月, 岡部幸子, 広川貴次, 清宮啓之, 長澤和夫
    • Organizer
      第62回 日本薬学会 関東支部大会
  • [Presentation] アルキニルボレートを介したα, β-不飽和エノンの新規合成法の開発2018

    • Author(s)
      藤田勇輝、阿嘉由樹、布田旭、福田勉、小野寺玄、木村正成
    • Organizer
      第65回有機金属化学討論会
  • [Presentation] マウスゲノムにおける遺伝子および転写産物の存在しない領域に集積するトラップクローンの探索2018

    • Author(s)
      齋藤桂花、堤成美、原田実穂、吉信公美子、荒木喜美、荒木正健
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] イノシトールリン脂質・PI(4)Pの新しい生理機能 : 膜接触部位形成と脂質交換輸送制御2018

    • Author(s)
      中津 史
    • Organizer
      2018年 生理学研究所研究会「オルガネラ膜ナノドメインの機能と動態」
    • Invited
  • [Presentation] イノシトールリン脂質によるメンプレンコンタクト形成と脂質交換輸送制御2018

    • Author(s)
      中津 史
    • Organizer
      日本分子生物学会年会
  • [Presentation] 内側中核アセチルコリン作動性神経による睡眠と記憶の制御2018

    • Author(s)
      山中章弘
    • Organizer
      記憶研究会2018 記憶・学習の基盤機構と回路研究の新展開へのアプローチ
    • Invited
  • [Presentation] オートファジー-分子機構と疾患との関わりー2018

    • Author(s)
      小松雅明
    • Organizer
      第40回 獣医学学術交流基金群講演会
    • Invited
  • [Presentation] オートファジーアダブターNDP52による新規NF-κB・細胞死制御機構2018

    • Author(s)
      及川大輔、駒倉啓大、徳永文稔
    • Organizer
      第91回日本生化学会大会
  • [Presentation] オートファジーシステムの作動原理と多様性2018

    • Author(s)
      小松雅明
    • Organizer
      第91回日本生化学会
    • Invited
  • [Presentation] オートファジーと疾患「選択的オートファジーによる転写制御」2018

    • Author(s)
      小松雅明
    • Organizer
      千里ライフサイエンスセミナー
    • Invited
  • [Presentation] オートファジーの生理機能2018

    • Author(s)
      小松雅明
    • Organizer
      第91回日本整形外科学会学術総会
    • Invited
  • [Presentation] オーバーシュート型シナプス形成異常による自閉症発現機構の解明2018

    • Author(s)
      佐々木 哲也
    • Organizer
      第2回 先進医薬研究報告会
  • [Presentation] オキサポロールを介したα, β-不飽和エノンの新規合成法の開発2018

    • Author(s)
      藤田勇輝、阿嘉由樹、布田旭、福田勉、小野寺玄、木村正成
    • Organizer
      第48回複素環化学討論会
  • [Presentation] オルガネラ Ca2+ ダイナミクスの光操作 ダイナミクスの光操作2018

    • Author(s)
      八尾 寛
    • Organizer
      生理学研究所研究会「神経回路の構築から機能発現に至る統合的理解」
  • [Presentation] オルガネラ光操作2018

    • Author(s)
      八尾 寛
    • Organizer
      第3回ルミノジェネティクス研究会, 2018/20-21, 蔵王町
    • Invited
  • [Presentation] がんとオートファジー2018

    • Author(s)
      小松雅明
    • Organizer
      第77回日本癌学会学術総会
    • Invited
  • [Presentation] がんの骨転移2018

    • Author(s)
      佐藤信吾
    • Organizer
      Juntendo Orthopedic Oncology Collaboration (JOOC)
    • Invited
  • [Presentation] がん研究におけるフェロトーシスの意義 ; シンポジウム1 : がん細胞と正常細胞の代謝機構2018

    • Author(s)
      豊國 仲哉
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] がん抑制遺伝子p53機能喪失とがん微小環境は協調的に胃がん悪性化を促進する2018

    • Author(s)
      大木理恵子
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] がん抑制因子から促進因子に変換するEphA2プロセシングの解明2018

    • Author(s)
      越川直彦
    • Organizer
      第77回日本癌学会学術総会
    • Invited
  • [Presentation] キノノイドジヒドロプテリジン還元酵素のリガンド認識機構のin silico解析2018

    • Author(s)
      河野はるか, 古田忠臣, 原怜, 一瀬宏
    • Organizer
      第91回日本生化学会大会
  • [Presentation] コンディショナルノックアウトを効率良く行うためのタモキシフェン投与法の検討2018

    • Author(s)
      吉信公美子、荒木美幸、森田彩花、国場訓、荒木喜美、荒木正健
    • Organizer
      日本遺伝学会第90回大会
  • [Presentation] サル背内側前頭皮質の神経細胞における時間認知機構2018

    • Author(s)
      千葉惇、生塩研一、稲瀬正彦
    • Organizer
      第41回日本神経科学大会
  • [Presentation] シアル酸転移酵素ST3Ga14欠損・オスマウスにおける生殖行動と代謝産物の関連性2018

    • Author(s)
      奥野貴哉、藤田明子, 織田弥伽、Paitoon Srimontri、加藤啓子
    • Organizer
      第65回日本実験動物学会
  • [Presentation] シアル酸転移性酵素ST3Ga14欠損オスマウスにおける生殖行動と代謝変化について2018

    • Author(s)
      奥野貴哉, 藤田明子, Siriporn Tangsdjai, 織田弥伽, 加藤啓子
    • Organizer
      第140回関西実験動物研究会
  • [Presentation] シアル酸転移性酵素ST3GalⅣ欠損マウスの統合失調症陰性症状について2018

    • Author(s)
      加藤啓子, 太田知沙, 廣田暖奈, 藤田明子
    • Organizer
      第161回獣医学会
  • [Presentation] シナプス形成抑制因子MDGA1の欠損は興奮/抑制バランスの抑制側へのシフトによる学習・記憶障害をもたらす2018

    • Author(s)
      山本 融, Steven A. Connor, Ina Ammendrup-Johnsen, 岸本 泰司, 原田 岳, 尾嶋 大喜, Razib Hossain Ann Marie Craig
    • Organizer
      第41回日本神経科学大会
  • [Presentation] 順遺伝学的手法より明らかとなったマウス副甲状腺ホルモンの腫瘍抑制効果2018

    • Author(s)
      奥村和弘、斎藤慈、磯貝恵理子、三浦 郁夫、若菜茂晴、山口碧、設楽浩志、多屋長治、木南凌、若林雄一
    • Organizer
      第65回実験動物学会総会
  • [Presentation] 新規タンキラーゼ阻害剤RK-287107は非臨床モデルで大腸がんを抑制する2018

    • Author(s)
      水谷アンナ、村松由起子、吉田喜香、清宮啓之
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 睡眠覚醒調節におけるオレキシンの役割2018

    • Author(s)
      山中章弘
    • Organizer
      第41回日本神経科学大会 ランチョンセミナー
    • Invited
  • [Presentation] 生活習慣病と睡眠覚醒とのただならぬ関係2018

    • Author(s)
      山中章弘
    • Organizer
      第3回Cortin Conference
    • Invited
  • [Presentation] TCRシグナルにおける直鎖状ユビキチン化の数理モデル解析2018

    • Author(s)
      後藤栄治、浜田大輔、及川大輔、鈴木貴、徳永文稔
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] トリソミー関連遺伝子による細胞サイズの調節2018

    • Author(s)
      山本一男、浅井将
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] パラジウム触媒作用を活用した3-ヒドロキシー4-ペンテン酸を共役ジエン等価体として用いるアルデヒドとの新形式炭素-炭素結合形成反応2018

    • Author(s)
      二ノ方亮、神路祇里歩、仲尾純弥、ラ エイ、福田勉、小野寺玄、木村正成
    • Organizer
      第67回有機金属化学討論会
  • [Presentation] パルミトイル化によるAMPA受容体制御の異常は発作感受性を上昇させる2018

    • Author(s)
      伊藤政之、金子雅規、阿部学、山崎真弥、夏目里恵、山田大輔、崎村建司、関口正幸、和田圭司、三品昌美、林 崇
    • Organizer
      第139回日本薬理学会関東部会
  • [Presentation] ビタミンC欠乏ODSラット脳におけるビオプテリン代謝の変化2018

    • Author(s)
      竹下直輝, 川出野絵, 鈴木若菜, 原怜, 堀尾文彦, 一瀬宏
    • Organizer
      日本ビタミン学会第70回大会
  • [Presentation] ファイバーレス光遺伝学を用いた睡眠覚醒と記憶制御のメカニズム解明2018

    • Author(s)
      山中章弘
    • Organizer
      第三回ルミノジェネティクス研究会
    • Invited
  • [Presentation] HSP72複合体の単離による血中微量タンパク質の同定2018

    • Author(s)
      塩田正之、田中昌子、鰐渕英機、徳永文稔
    • Organizer
      第13回臨床ストレス応答学会大会
  • [Presentation] 副甲状腺ホルモンPTHの腫瘍増殖抑制効果2018

    • Author(s)
      奥村和弘、斎藤慈、磯貝恵理子、若林雄一
    • Organizer
      第27回日本癌病態治療研究会
  • [Presentation] ホスフィンーボラン配位子を用いたイリジウム触媒による 2-アリールピリジン類のオルト位シリル化反応2018

    • Author(s)
      松添哲、阿野山恵多、小野寺玄、福田勉、木村正成
    • Organizer
      第66回有機金属化学討論会
  • [Presentation] マウスうつによる環境, 医薬, 食品のスクリーニング2018

    • Author(s)
      加藤啓子
    • Organizer
      イノベーション・ジャパン
  • [Presentation] ミトコンドリア機能制御と健康長寿への応用について2018

    • Author(s)
      魏 范研
    • Organizer
      ライフエンジニアリング部門シンポジウム2018
    • Invited
  • [Presentation] ミトコンドリア代謝を標的とした肉腫治療の可能性2018

    • Author(s)
      岸 真五、朴木寛也、城戸顕、辻内俊文、田中康仁、國安弘基
    • Organizer
      第3回日本整形外科学会基礎学術集会
    • Invited
  • [Presentation] コムギ無細胞系を用いて作製した脱ユビキチン化酵素(DUB)プロテインアレイによるポリユビキチン鎖基質特異性とDUB阻害剤の選択性評価2018

    • Author(s)
      高橋宏隆、山中聡士、桒田翔平、後藤栄治、今井賢一郎、富井健太郎、佐藤裕介、深井周也、徳永文稔、澤崎達也
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] メンブレンコンタクトにおける脂質交換輸送とその生理機能2018

    • Author(s)
      中津 史
    • Organizer
      第91回日本生化学大会
  • [Presentation] 薬学生に対する放射線健康リスク科学教育の現状と問題点2018

    • Author(s)
      高井伸彦
    • Organizer
      第61回日本放射線影響学会
    • Invited
  • [Presentation] ユビキチン様ドメインを有するPol Ⅱ-CTD脱リン酸化酵素による遺伝子発現制御2018

    • Author(s)
      加藤ありさ, 和仁翔太郎, 加納未由希, 石黒尋保, 杉田愛, 田渕圭章, 大熊芳明, 廣瀬豊
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 亜鉛(Ⅱ)トリフラートによるアルキン活性化を基盤とした含窒素スキャフォールド群の骨格多様化合成2018

    • Author(s)
      頼元 貞巖・恒川 佳諒・市野 智也・坪内 彰・前田 理・大栗博毅
    • Organizer
      第114回有機合成シンポジウム
  • [Presentation] 意思決定時におけるサル中脳ドーパミンニューロンと前頭眼窩ニューロンの報酬価値と選択行動の表現形式2018

    • Author(s)
      惲夢曦、川合隆嗣、禰占雅史、山田洋、松本正幸
    • Organizer
      第41回日本神経科学大会
  • [Presentation] 遺伝子異常からコルチゾール産生副腎腫瘍の病態に迫る2018

    • Author(s)
      鈴木佐和子
    • Organizer
      第28回臨床内分泌代謝update
    • Invited
  • [Presentation] 黄色ブドウ球菌感染創における C/EBP α-miR-223-IL6分泌経路の機能解析2018

    • Author(s)
      森亮一
    • Organizer
      第107回日本病理学会総会
  • [Presentation] 下垂体神経内分泌腫瘍で同定されたがん抑制遺伝子PHLDA3変異の機能解析2018

    • Author(s)
      冨永 航平、山口 陽子、永田 喜三郎、大木 理恵子
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 核酸アルキル化能を有する天然物群の化学-酵素ハイブリッド合成2018

    • Author(s)
      谷藤 涼・浅野 竜太郎・南 篤志・及川英秋・大栗博毅
    • Organizer
      日本化学会 生体機能関連化学部会若手の会 第30回サマースクール
  • [Presentation] 機能性下垂体腺腫の手術について2018

    • Author(s)
      岡田正康
    • Organizer
      第72回新潟脳神経外科懇話会
  • [Presentation] 興奮性シナプスにおける神経伝達物質受容体のパルミトイル化による膜局在制御2018

    • Author(s)
      林 崇
    • Organizer
      第40回日本生物学的精神医学会・第61回日本神経化学会大会 合同年会
    • Invited
  • [Presentation] 蛍光標識を用いたドーパミン結合に応答するチロシン水酸化酵素の構造変化の解析2018

    • Author(s)
      犬飼駿弥, 原怜, 一瀬宏
    • Organizer
      第91回日本生化学会大会
  • [Presentation] 血小板由来TGF-βによる骨肉腫細胞の凝固系の調節2018

    • Author(s)
      市川 二郎(山梨大学 大学院整形), 安藤 隆, 齋藤 正憲, 波呂 浩孝
    • Organizer
      第51回日本整形外科学会骨・軟部腫瘍学術集会
  • [Presentation] 血小板由来TGF-βはsmad3を介して骨肉腫細胞の組織因子発現を誘導する2018

    • Author(s)
      齋藤 正憲, 市川 二郎, 安藤 隆, 波呂 浩孝
    • Organizer
      第34回日本整形外科学会基礎学術集会
  • [Presentation] 元素置換戦略による抗感染症リード化合物群の創製2018

    • Author(s)
      大栗博毅
    • Organizer
      第62回日本薬学会関東支部大会 シンポジウムS1 創薬を支える有機合成化学
    • Invited
  • [Presentation] 好中球由来miR-223の発現抑制は皮膚感染創における黄色ブドウ球菌排除を促進する2018

    • Author(s)
      森亮一
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 構造化照明による超解像顕微鏡(SIM)で明らかになった神経突起先端の3次元構造2018

    • Author(s)
      野住 素広
    • Organizer
      日本分子生物学会年会
    • Invited
  • [Presentation] 高ω3多価不飽和脂肪酸食摂取の抗うつ様効果には側坐核のドパミン神経系が関与する2018

    • Author(s)
      竹内 絵理、山田 大輔、斎藤 顕宜、伊藤 政之、林 崇、山田 光彦、和田 圭司、関口 正幸
    • Organizer
      第41回日本神経科学大会
  • [Presentation] 高頻度チロシリン酸化MAP1Bの神経発生過程における機能解析2018

    • Author(s)
      伊藤 泰行
    • Organizer
      次世代脳プロジェクト 冬のシンポジウム
  • [Presentation] 細菌によるヒト細胞分化の乗っ取り2018

    • Author(s)
      Naofumi Ito, Shah Adil Ishtiyaq Ahmad, Mohammad Badrul Anam, Kunimasa Ohta.
    • Organizer
      くまだい研究フェア
    • Invited
  • [Presentation] 細菌感染による細胞分化可塑性の誘導2018

    • Author(s)
      伊藤尚文、Shah Adil Ishtiyaq Ahmad、Mohammad Badrul Anam、太田訓正
    • Organizer
      第39回日本分子生物学会
  • [Presentation] 細胞内で架橋形成する機能未知タンパク質WDR(WD-like repeat) 54の機能解析2018

    • Author(s)
      前田 朱音, 西野 扶, 菅 裕, 八木 俊樹, 小西 博昭
    • Organizer
      第91回日本生化学会大会
  • [Presentation] 細胞内領域によるDectin-1の種特異的リガンドスペクトラム調節機構2018

    • Author(s)
      本園 千尋、高野 智嗣、今井 崇史、園田 康平、山崎 晶
    • Organizer
      第91回日本生化学学会大会
    • Invited
  • [Presentation] 子どもの病気と薬「放射線ひばくと子供への影響」2018

    • Author(s)
      高井伸彦
    • Organizer
      H30教員免許状更新講習会
    • Invited
  • [Presentation] 視床を抑制する視床網様核の集合Ca2+活動は新規発振現象を示す2018

    • Author(s)
      高田則雄、夏堀晃世、三村將、田中謙二
    • Organizer
      第41回日本神経科学会
  • [Presentation] 次世代HTLV-1クロナリティ解析法の開発とその応用に向けて2018

    • Author(s)
      斎藤益満、山内俊輔、佐々木大介、長谷川寛雄
    • Organizer
      第5回日本HTLV-1学会
  • [Presentation] 治療に難渋しているACTH産生下垂体腺腫の1例2018

    • Author(s)
      岡田正康、米岡有一郎、温城太郎、本橋邦夫、菊池文平、長谷川仁、大石誠、藤井幸彦
    • Organizer
      第108回新潟内分泌代謝同好会
  • [Presentation] 自然免疫制御に関わる新規RING型E3(RNF126)の同定と機能解析2018

    • Author(s)
      阿部貴則、及川大輔、寺脇正剛、後藤栄治、高橋宏隆、大竹史明、川原裕之、堀居拓郎、畑田出穂、佐伯泰、田中啓二、澤崎達也、徳永文稔
    • Organizer
      第41回日本分子生物学会
  • [Presentation] 自発運動の感覚フィードバック処理における運動野-体性感覚野相互作用2018

    • Author(s)
      望月圭、中陦克己、稲瀬正彦、村田哲
    • Organizer
      第41回日本神経科学大会
  • [Presentation] 順遺伝学に基づくMSMマウスのがん耐性に関与する遺伝子の同定2018

    • Author(s)
      奥村和弘
    • Organizer
      第31回モロシヌス研究会
    • Invited
  • [Presentation] 小細胞肺癌の同所移植モデルの転移巣において高発現する遺伝子の探索2018

    • Author(s)
      坂本修一、川田学
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 上皮間葉転換誘導因子の細胞内代謝における機能解析.2018

    • Author(s)
      竹洞裕貴, 高倉勇気, 岡田和之, 杉野歩美, 堀 直人, 町田萌香, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第62回日本薬学会関東支部大会
  • [Presentation] 上皮間葉転換誘導因子の細胞内代謝における役割.2018

    • Author(s)
      竹洞裕貴, 高倉勇気, 岡田和之, 杉野歩美, 堀 直人, 町田萌香, 尾間萌歌, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 新規LUBAC阻害剤、HOIPIN-1の作用機序と病態抑制効果2018

    • Author(s)
      及川大輔、花田和希、菅原弘二、寺脇正剛、水上裕加里、鶴田大輔、坂本信二、徳永文稔
    • Organizer
      第65回日本生化学会近畿支部例会
  • [Presentation] 新規がんシグナルDickkopfl-CKAP4経路は、がん治療および診断のための分子標的となる。2018

    • Author(s)
      Akira Kikuchi
    • Organizer
      第41回日本分子生物学会
    • Invited
  • [Presentation] 神経成長における超解像度レベルの脂質ドメイン可視化とその構成脂質特性の解析2018

    • Author(s)
      五十嵐 道弘
    • Organizer
      第4回リポクオリティ班会議
  • [Presentation] 睡眠覚醒調節、痛み調節におけるオレキシンの役割2018

    • Author(s)
      山中章弘
    • Organizer
      第12回日本緩和医療薬学会年会
    • Invited
  • [Presentation] 成年マウスの低酸素症後の100%酸素による再酸素化は肝障害を引き起こす2018

    • Author(s)
      植木正明
    • Organizer
      日本麻酔科学会第65回学術集会
  • [Presentation] 生理活性天然物の迅速合成・骨格改変の新戦略2018

    • Author(s)
      大栗博毅
    • Organizer
      第29回万有仙台シンポジウム 未来を指向した有機合成化学
    • Invited
  • [Presentation] 線虫のダイサー関連へリカーゼDRH-1とDRH-3の生化学的研究2018

    • Author(s)
      小林大士、村上匠蔵、木村康誠、白木 隼、広瀬 侑、浴 俊彦
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 選択的オートファジー : 創薬ターゲットとなるか?2018

    • Author(s)
      小松雅明
    • Organizer
      日本分析化学会第67年会
    • Invited
  • [Presentation] 選択的オートファジーによるエピジェネティクス制御2018

    • Author(s)
      小松雅明
    • Organizer
      第11回オートファジー研究会
  • [Presentation] 選択的オートファジーによる脂肪酸酸化制御2018

    • Author(s)
      小松雅明
    • Organizer
      第6回がんと代謝研究会
    • Invited
  • [Presentation] 側頭葉てんかんモデルマウスにおける代謝変化2018

    • Author(s)
      太田 真菜美, 藤田明子, 加藤啓子
    • Organizer
      第140回関西実験動物研究会
  • [Presentation] 大脳皮質神経細胞におけるアクチン細胞骨格制御因子Fhod3の機能解析2018

    • Author(s)
      根本隆行、Hikmawan Wahyu Sulistomo、武谷 立
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム若手支援技術講習会
  • [Presentation] 超解像度顕微鏡による成長門錐の3次元細胞内構造解析2018

    • Author(s)
      野住 素広
    • Organizer
      第41回日本神経科学大会
  • [Presentation] 天然物の迅速合成・構造多様化・新機能創出を目指して2018

    • Author(s)
      大栗博毅
    • Organizer
      昭和薬科大学講演会
    • Invited
  • [Presentation] 天然物の迅速合成・骨格改変による創薬候補分子群創製を目指して2018

    • Author(s)
      大栗博毅
    • Organizer
      創薬談話会2018 次世代を担う若手のためのメディシナルケミストリーフォーラム
    • Invited
  • [Presentation] 転写と共役した選択的ポリ(A)付加調節の分子機構2018

    • Author(s)
      竹田深雪, 京角啓太, 寺田公介, 畑山光, 大熊芳明, 廣瀬豊
    • Organizer
      第20回日本RNA学会年会
  • [Presentation] 転写と共役した選択的ボリ(A)付加調節機構2018

    • Author(s)
      廣瀬豊, 竹田深雪, 京角啓太, 寺田公介, 畑山光, 大熊芳明
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 転写共役因子Vestigial-like family 3のHippo pathwayにおける機能.2018

    • Author(s)
      堀 直人, 高倉勇気, 岡田和之, 竹洞裕貴, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第62回日本薬学会関東支部大会
  • [Presentation] 転写共役因子VGLL3によるオートファジーの機能解明.2018

    • Author(s)
      町田萌香, 高倉勇気, 岡田和之, 竹洞裕貴, 尾間萌歌, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第62回日本薬学会関東支部大会
  • [Presentation] 転写共役因子YAP/TAZを分解する新規シグナル伝達解析.2018

    • Author(s)
      岡田和之, 高倉勇気, 竹洞裕貴, 堀 直人, 平井直人, 高野博之, 山口直人, 山口憲孝.
    • Organizer
      第41回日本分子生物学会年会
  • [Presentation] 脳・神経細胞におけるアクチン細胞骨格制御因子Fhod3の機能解析2018

    • Author(s)
      根本隆行、Hikmawan Wahyu Sulistomo、武谷 立
    • Organizer
      第13回トランスポーター研究会
  • [Presentation] 脳腫瘍形成におけるミクログリアの役割の解析2018

    • Author(s)
      高祖秀登
    • Organizer
      次世代脳プロジェクト 冬のシンポジウム
  • [Presentation] 分泌性p53標的遺伝子p53PAD7の新規受容体の同定と細胞増殖停止機能の解明2018

    • Author(s)
      滝川 雅大、石川 冬木、大木 理恵子
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] 変異型インフルエンザウイルスH3N2のHA開裂におけるTMPRSS2利用能と病原性解析2018

    • Author(s)
      酒井宏治、永田直也、須崎百合子、竹原一明、網康至
    • Organizer
      第161回日本獣医学会学術集会
  • [Presentation] 報酬学習の履歴とストレス反応性-行動と結果の随伴性の学習によるレジリエンス生起-2018

    • Author(s)
      井口善生
    • Organizer
      次世代脳プロジェクト冬のシンポジウム
  • [Presentation] 未分化がんにおける 多能性関連遺伝子の発現2018

    • Author(s)
      柴田 博史, 大橋 敏充, 林 寿光, 西堀 丈純, 久世 文也, 青木 光広, 山田 泰広, 伊藤 八次
    • Organizer
      第174回 日本耳鼻咽喉科学会 東海地方部会連合講演会
  • [Presentation] 野生型THおよびS40E変異型THの過剰発現による線条体ドーパミン量の変化2018

    • Author(s)
      岩下由佳, 宗実悠佳, 原怜, 村松慎一, 一瀬宏
    • Organizer
      第33回日本大脳基底核研究会
  • [Presentation] すい臓がん細胞と間質細胞の共培養によるキナーゼ阻害剤抵抗性の解析2018

    • Author(s)
      立田大輔、吉田潤次郎、川田 学
    • Organizer
      第22回がん分子標的治療学会学術集会
  • [Presentation] Analysis of the mechanism of kinase inhibitors resistance by Pancreatic tumor-stromal cell interactions2018

    • Author(s)
      Daisuke Tatsuda, Junjiro Yoshida, Manabu Kawada
    • Organizer
      第77回日本癌学会学術総会
  • [Presentation] Coccoquinones, new anthraquinone derivatives, suppress p53-dependent growth of cancer cells2018

    • Author(s)
      Daisuke Tatsuda, Isao Momose, Masahide Amemiya, Kengo Sumiyoshi, Takumi Watanabe, Manabu Kawada, Masakatsu Shibasaki
    • Organizer
      30th EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium
    • Int'l Joint Research
  • [Book] 内分泌機能検査実施マニュアル 改訂第3版2019

    • Author(s)
      鈴木佐和子、龍野一郎、横手幸太郎
    • Publisher
      診断と治療社
  • [Book] 生化学2018

    • Author(s)
      岩崎信太郎
    • Pages
      211-215
    • Total Pages
      6
    • Publisher
      公益社団法人日本生化学会
  • [Book] 臨床消化器内科(8月号 : 特集膵神経内分泌腫瘍update)2018

    • Author(s)
      冨永 航平、チン ヨ、大木 理恵子
    • Total Pages
      1099-1109
    • Publisher
      日本メディカルセンター
  • [Book] ラング・デール薬理学 原書8版2018

    • Author(s)
      Rang HP, Rittter JM, Flower RJ, Hnederson G 原著 渡邉直樹 監訳
    • Pages
      295-316, 413-426, 505-512, 853-858
    • Total Pages
      878
    • Publisher
      エルゼビア・丸善出版
  • [Book] Plasma Medical Science2018

    • Author(s)
      Toyokuni S, Ikehara Y, Kikkawa F, Hori M
    • Pages
      1-438
    • Total Pages
      438
    • Publisher
      Academic Press
  • [Book] Handbook of Clinical Neurology (Thermoregulation : From Basic Neuroscience to Clinical Neurology Part I)2018

    • Author(s)
      Nakamura, K.
    • Pages
      263-279
    • Total Pages
      463
    • Publisher
      Elsevier
  • [Book] 実験医学増刊 Vol. 362018

    • Author(s)
      本園 千尋
    • Pages
      125-130
    • Total Pages
      242
    • Publisher
      羊土社
  • [Book] 栄養2018

    • Author(s)
      森 亮一、朴 盛浚、下川 功
    • Pages
      4-8
    • Total Pages
      46
    • Publisher
      ジェフコーポレーション
  • [Book] 生化学2018

    • Author(s)
      昆 俊亮
    • Pages
      715-718
    • Total Pages
      4
    • Publisher
      日本生化学会
  • [Book] アップコンバージョンプロープー生体深部のイメージングや光操作に向けて、実験医学増刊 Vol. 36 No. 20「生きてるものは全部観る! イメージングの選び方・使い方100+」, 原田慶恵, 永井健治/編,2018

    • Author(s)
      八尾寛
    • Pages
      188-189
    • Total Pages
      236
    • Publisher
      羊土社
  • [Book] Chemical Assembly Lines for Skeletally Diverse Indole Alkaloids” Molecular Technology : Live Innovation, Volume 22018

    • Author(s)
      Hiroki Oguri
    • Pages
      43-70
    • Total Pages
      370
    • Publisher
      WILEY-VCH Verlag GmbH & Co. KGaA
  • [Book] 天然有機化合物の全合成 : 独創的なものづくりの反応と戦略(日本化学会 CSJカレントレビュー)2018

    • Author(s)
      難波康祐、楠見武徳、井上将行、山口潤一郎、石川勇人、占部大介、横島聡、平井剛、菅敏幸、中田雅久、石川勇、西川俊夫、谷野圭持、長友優典、大森建、竜田邦明、徳山英利、田上克也、不破春彦、廣瀬友靖、大栗博毅
    • Pages
      167-174
    • Total Pages
      208
    • Publisher
      化学同人
  • [Remarks] 北海道大学大学院薬学研究院生化学研究室ホームページ

    • URL

      http://www.pharm.hokudai.ac.jp/seika/index.html

  • [Remarks] 北海道大学遺伝子病制御研究所分子腫瘍分野ホームページ

    • URL

      http://www.igm.hokudai.ac.jp/oncology/

  • [Remarks] 福島県立医科大学研究成果情報ページ

    • URL

      https://www.fmu.ac.jp/univ/kenkyuseika/research/1709.html

  • [Remarks] 公益財団法人微生物化学研究所

    • URL

      https://www.bikaken.or.jp

  • [Remarks] 東京理科大学 生命医科学研究所 昆 俊亮 研究室 ホームページ

    • URL

      https://konshunsukelab.wixsite.com/rs-tus

  • [Remarks] 新潟大学脳研究所 動物資源開発研究分野 ホームページ

    • URL

      http://www.bri.niigata-u.ac.jp/field/lab_animal/index.html

  • [Remarks] 新潟大学脳研究所 脳研コラム ホームページ

    • URL

      http://www.bri.niigata-u.ac.jp/result/lab_animal/000126.html

  • [Remarks] 新潟大学脳研究所 研究成果・実績 ホームページ

    • URL

      http://www.bri.niigata-u.ac.jp/result/lab_animal/000833.html

  • [Remarks] 新潟大学大学院医歯学総合研究科機能制御学分野のホームページ

    • URL

      https://www.med.niigata-u.ac.jp/mit/

  • [Remarks] 新潟大学医歯学系神経生化学(生化学第二)ホームページ

    • URL

      https://www.med.niigata-u.ac.jp/bc2/index.html

  • [Remarks] 新潟大学脳研究所 研究業績ホームページ

    • URL

      http://www.bri.niigata-u.ac.jp/result/surgery/001033.html

  • [Remarks] 富山大学薬学部分子神経生物学研究室ホームページ

    • URL

      http://www.pha.u-toyama.ac.jp/biochel/index-j.html

  • [Remarks] 金沢大学広報ホームページ

    • URL

      https://www.kanazawa-u.ac.jp/latest-research/64909

  • [Remarks] 金沢大学がん進展制御研究室腫瘍分子生物学研究分野ホームページ

    • URL

      http://omb.w3.kanazawa-u.ac.jp/index.html

  • [Remarks] 名古屋大学大学院医学系研究科統合生理学ホームページ

    • URL

      https://www.med.nagoya-u.ac.jp/physio12/

  • [Remarks] 基礎生物学研究所神経細胞生物学研究室ホームページ

    • URL

      http://www.nibb.ac.jp/neurocel/index.html

  • [Remarks] 滋賀医科大学分子病態生化学ホームページ

    • URL

      http://www.shiga-med.ac.jp/~hqbioch2/

  • [Remarks] 京都大学医学研究科 小川正晃研究室ホームページ

    • URL

      https://sites.google.com/view/ogawagroup/

  • [Remarks] 老化とアンチエイジング研究室ホームページ

    • URL

      http://www.anti-aging.jpn.com/

  • [Remarks] 大阪大学微生物病研究所分子免疫制御分野 山崎研究室ホームページ

    • URL

      http://molimm.biken.osaka-u.ac.jp

  • [Remarks] 大阪市立大学大学院医学研究科分子病態学研究室ホームページ

    • URL

      http://osaka-cu-lseika.umin.jp/

  • [Remarks] 広島大学 神経生理学ホームページ

    • URL

      https://home.hiroshima-u.ac.jp/physio12/index.html

  • [Remarks] 香川大学医学部薬理学研究室ホームページ

    • URL

      http://www.kms.ac.jp/~yakuri/

  • [Remarks] 九州大学生体防御医学研究所 分子医科学分野 ホームページ

    • URL

      http://www.bioreg.kyushu-u.ac.jp/saibou/index.html

  • [Remarks] 九州大学大学院薬学研究院 創薬腫瘍科学講座ホームページ

    • URL

      http://shuyo.phar.kyushu-u.ac.jp/

  • [Remarks] 福岡大学てんかん分子病態研究所ホームページ

    • URL

      http://www.med.fukuoka-u.ac.jp/epilepsy/index.html

  • [Remarks] 熊本大学発生医学研究所脳発生分野ホームページ

    • URL

      http://www.imeg.kumamoto-u.ac.jp/bunya_top/brain_morphogenesis/

  • [Remarks] 熊本大学国際先端医学研究所ホームページpublication欄

    • URL

      http://ircms.kumamoto-u.ac.jp/publications/2017/01/identification-of-stem-cells-in-the-epithelium-of-the-stomach-corpus-and-antrum-of-mice.html

  • [Remarks] 鹿児島大学大学院医歯学総合研究科分子腫瘍学分野ホームページ

    • URL

      http://www.kufm.kagoshima-u.ac.jp/~molonc12/

  • [Remarks] 北海道大学青沼研究室ホームページ

    • URL

      http://ncmac2.es.hokudai.ac.jp/index.html

  • [Remarks] 新潟大学オートファジー、代謝と神経変性疾患ホームページ

    • URL

      https://www.med.niigata-u.ac.jp/bcl/A3/index.html

  • [Remarks] 大阪大学分子病態生化学研究室ホームページ

    • URL

      http://www.med.osaka-u.ac.jp/pub/molbiobc/index.html

  • [Remarks] 日本糖尿病学会ホームページ きらり女性医師

    • URL

      http://www.jds.or.jp/modules/education/index.php?content_id=19

  • [Remarks] 先端モデル動物支援プラットフォームホームページ

    • URL

      http://model.umin.jp/

  • [Remarks] 東京大学医科学研究所 学術研究基盤支援室ホームページ

    • URL

      http://academicsupport.jp/index.html

  • [Remarks] 東京大学大学院薬学系研究科プレスリリース

    • URL

      http://www.f.u-tokyo.ac.jp/topics.html?page=1&key=1535624631

  • [Remarks] 東京大学医科学研究所井上研究室ホームページ

    • URL

      http://www.f.u-tokyo.ac.jp/inoue/

  • [Remarks]

  • [Remarks] 関西医科大学

    • URL

      http://www.kmu.ac.jp/facully/medical/calegory2/unit4.html

  • [Remarks] 京都大学生命有機化学研究室ホームページ

    • URL

      http://www.orgchem.kais.kyoto-u.ac.jp/

  • [Remarks] 可変型遺伝子トラップクローンデータペース(EGTC)

    • URL

      http://egtc.jp

  • [Remarks] 生理学研究所古瀬研究室ホームページ

    • URL

      http://www.nips.ac.jp/dcs/

  • [Remarks] 礒村宜和Researchmap

    • URL

      https://researchmap.jp/yoshikazuisomura/

  • [Remarks] 東京医科歯科大学ホームページ(プレスリリース)

    • URL

      http://www.tmd.ac.jp/press-release/20180213_1/index.html

  • [Remarks] 東京医科歯科大学ホームページ(プレスリリース)

    • URL

      http://www.tmd.ac.jp/english/press-release/20180319_1/index.html

  • [Remarks] 鳥取大学医学部生命科学科細胞工学研究室ホームページ

    • URL

      https://saiboukougaku.jimdo.com/

  • [Remarks] 鳥取大学 染色体工学研究センター

    • URL

      http://www.med.tottori-u.ac.jp/chromosome/

  • [Remarks] 東京農工大学 栗研究室ホームページ

    • URL

      http://web.tuat.ac.jp/_h_oguri/index.html

  • [Remarks] プレスリリース(2019年1月23日)「光ファイバーを用いない「ファイバーレス神経活動操作」の開発とその応用による長期間のマウス行動制御の達成」

    • URL

      https://www.tohoku.ac.jp/japanese/2019/01/press-20190122-02-hikari.html

  • [Remarks] プレスリリース(2019年3月12日)「触覚パターンを瞬時かつ鋭敏に把握するメカニズムの解明-光を用いて脳の多変量計算論理を理解する」

    • URL

      https://www.tohoku.ac.jp/japanese/2019/03/press-20190312-02-syokkaku.html

  • [Remarks] 長崎国際大学薬学部 教員・研究紹介 支援に関する結果を、1月の発表会にて報告したのち、本学のHPに内容を掲載予定

    • URL

      https://wwwl.niu.ac.jp/about/teacher/detail.html?tid=188

  • [Remarks] 名古屋市立大学 分子毒性学分野ホームページ

    • URL

      http://www.med.nagoya-cu.ac.jp/moltox.dir/

  • [Remarks] 名古屋大学環境医学研究所 神経系分野Ⅱホームページ

    • URL

      http://www.riem.nagoya-u.ac.jp/4/drofl/nr/

  • [Remarks] 新潟大学小松雅明研究室ホームページ

    • URL

      http://www.med.niigata-u.ac.jp/bcl/index.html

  • [Remarks] 東京工業大学一瀬研究室ホームページ

    • URL

      http://www.bh4.bio.titech.ac.jp/index.html

  • [Remarks] 岩崎研究室ホームページ

    • URL

      http://iwasakirna.com/

  • [Remarks] 岩崎研究室ホームページ

    • URL

      http://www.riken.jp/research/labs/chief/rna_sys_biochem/

  • [Remarks] 京都産業大学教員紹介

    • URL

      http://www.kyoto-su.ac.jp/faculty/professors/nls/kato-keiko.html

  • [Remarks] 大阪市立大学大学院医学研究科分子病態学研究室ホームページ

    • URL

      http://osaka-cu-lseika.umin.jp/link

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    • URL

      http://www.bioa.eng.osaka-cu.ac.jp/biointerface/Biomedical_Advanced_Materials/2017Sympo_report.html

  • [Remarks]

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    • URL

      https://www.osaka-cu.ac.jp/ja/news/2016/160824

  • [Patent(Industrial Property Rights)] パーキンソン病の診断指標2019

    • Inventor(s)
      山本融、正木勉、出口一志、鎌田正紀、高田忠幸、國土曜平、野中和香子、青江真吾、et al.
    • Industrial Property Rights Holder
      香川大学・北海道大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2019-033661
  • [Patent(Industrial Property Rights)] テトラヒドロイソキノリン環含有化合物の製造方法2019

    • Inventor(s)
      大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道大)
    • Industrial Property Rights Holder
      大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道大)
    • Industrial Property Rights Type
      特許権
    • Industrial Property Number
      PCT/JP2019/009128
    • Overseas
  • [Patent(Industrial Property Rights)] 第四世代EGFRチロシンキナーゼ阻害剤2018

    • Inventor(s)
      岩尾正倫、福田勉、石橋郁人、上原至雅、西谷直之、奥裕介、旦慎吾、矢守隆夫
    • Industrial Property Rights Holder
      国立大学法人長崎大学、学校法人岩手医科大学
    • Industrial Property Rights Type
      特許権
    • Industrial Property Number
      PCT/JP2018/13370
    • Overseas
  • [Patent(Industrial Property Rights)] 抗膵がん剤2018

    • Inventor(s)
      長澤和夫、松田未沙子、馬悦、清宮啓之
    • Industrial Property Rights Holder
      国立大学法人東京農工大学、公益財団法人がん研究会
    • Industrial Property Rights Type
      特許権
    • Industrial Property Number
      特願2018-136579
  • [Patent(Industrial Property Rights)] 第四世代EGFRチロシンキナーゼ阻害剤2018

    • Inventor(s)
      岩尾正倫、福田勉、石橋郁人、上原至雅、西谷直之、奥裕介、旦慎吾、矢守隆夫
    • Industrial Property Rights Holder
      国立大学法人長崎大学学校法人岩手医科大学公益財団法人がん研究会
    • Industrial Property Rights Type
      特許権
    • Industrial Property Number
      PCT/JP2018/13370
    • Overseas
  • [Patent(Industrial Property Rights)] マウスのてんかんバイオマーカー2018

    • Inventor(s)
      加藤啓子、藤田明子
    • Industrial Property Rights Holder
      京都産業大学
    • Industrial Property Rights Type
      特許権
    • Industrial Property Number
      特願2018-233113
  • [Patent(Industrial Property Rights)] がんの予後判定および診断方法2018

    • Inventor(s)
      中川将利、吉村 徹、吉田栄作、清木元治、越川直彦
    • Industrial Property Rights Holder
      東京大学、アボットジャパン
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2017-648**
  • [Patent(Industrial Property Rights)] SPRをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物2018

    • Inventor(s)
      一瀬宏、原怜、吉田勇輝、村松慎一、加藤節子
    • Industrial Property Rights Holder
      東京工業大学、自治医科大学、加藤節子
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2018-206643
  • [Patent(Industrial Property Rights)] HTLV-1挿入部位同定方法2018

    • Inventor(s)
      斎藤益満、長谷川寛雄
    • Industrial Property Rights Holder
      ヒューマンサイエンス財団、長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2018-128683
  • [Patent(Industrial Property Rights)] アルカロイド骨格を有する両親媒性化合物2018

    • Inventor(s)
      大栗博毅(東京農工大)、村岡貴博(東京農工大)、土屋菜奈(東京農工大)、笠勇之介(東京農工大)
    • Industrial Property Rights Holder
      大栗博毅(東京農工大)、村岡貴博(東京農工大)、土屋菜奈(東京農工大)、笠勇之介(東京農工大)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2018-206817
  • [Patent(Industrial Property Rights)] テトラヒドロイソキノリン環含有化合物の製造方法2018

    • Inventor(s)
      大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道大)
    • Industrial Property Rights Holder
      大栗博毅(東京農工大)、谷藤涼(東京農工大)、及川英秋(北海道大)
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2018-144906

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Published: 2020-03-17   Modified: 2023-03-16  

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