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2007 Fiscal Year Final Research Report Summary

3D Manipulation and surface-processing of non-spherical micro-objects using laser beams

Research Project

Project/Area Number 17560241
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

TANAKA Yoshio  National Institute of Advanced Industrial Science and Technology, AIST, Health Technology Research Center, Senior Research Scintist (30357454)

Co-Investigator(Kenkyū-buntansha) HIRANO Ken  AIST, Research Scintist (80392653)
Project Period (FY) 2005 – 2007
KeywordsOptical Tweezers / Micro Manipulation / Image Processing
Research Abstract

Laser manipulation is an important technique suitable for controlling/handling fluid-borne objects at length scales ranging from sub-micrometers to micrometers in a closed space such as Lab-on-a-Chip. However, almost all previous works have been limited to two-dimensional(2D) space or spherical objects such as beads, droplets and others. Furthermore, the control system and user-interfaces of conventional optical tweezers system is insufficient to manipulate objects in 3D working space, if the intention is to manipulate dexterously or automatically the objects in real time. The manipulation of arbitrarily shaped objects in 3D space is essential and of widespread importance, since many naturally occurring objects as well as microfabricated objects are not spherical. Automatic manipulation based on image processing techniques will be also important for Lab-on-a-Chips.
In our project, we have developed a personal computer(PC) controlled 3D laser trapping-ablation system combined with real-t … More ime image processing techniques and mouse-controlled user-interfaces and have carried out several demonstrations using samples with various optical properties and shapes. We have also proposed a new non-contact 3D manipulation technique based on 'optical lever effect' for non-spherical micro-objects. The three-beam optical tweezers, the line-scanning laser trap and the optical-lever manipulation using our system have enabled real-time orientation control in 3D space. Tilt angle control translation and rotation of the non-spherical micro objects were demonstrated by various manipulation schemes. Although we have dealt only with a few samples with non-spherical shape, these results, we believe, could open up new possibilities for positioning and orienting arbitrarily shaped objects in 3D space using laser trapping. Furthermore, it is expected that the manipulation schemes coupled with computer vision techniques will perform fully-automated dexterous manipulations of non-spherical objects in various research fields as well as MEMS and Lab-on-a-Chip. Less

  • Research Products

    (36 results)

All 2008 2007 2006 2005

All Journal Article (11 results) (of which Peer Reviewed: 5 results) Presentation (23 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Real-time three-dimensional orientation control of non-spherical micro-objects using laser trapping2007

    • Author(s)
      Yoshio Tanaka, et. al.
    • Journal Title

      Electronics Letters Vol.43-7

      Pages: 412-414

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Hideya Nagata, et. al.
    • Journal Title

      Proceedings of MicroTAS2007 Vol.2

      Pages: 1176-1178

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Single molecule analysis of condensed DNA(Measurement of condensation speed and single molecule size using laser trapping)2007

    • Author(s)
      Tomomi Ishido, et. al.
    • Journal Title

      Proceedings of MicroTAS2007 Vol.2

      Pages: 1399-1201

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Hideya Nagata, et. al.
    • Journal Title

      Proc. MicroTAS2007 Vol. 2

      Pages: 1176-1178

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Single molecule analysis of condensed DNA (Measurement of condensation speed and single molecule size using laser trapping)2007

    • Author(s)
      Tomomi Ishido, et. al.
    • Journal Title

      Proc. MicroTAS2007 Vol.2

      Pages: 1399-1201

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Development of PC Controlled Laser Manipulation System with Image Processing Functions2006

    • Author(s)
      Yoshio Tanaka, et. al.
    • Journal Title

      Proc.of SPIE(Optomechatronic Actuators, Manipulation, and Systems Control) Vol.6374

      Pages: 63740P1-8

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Development of PC controlledcaser manipulation system with image processing functions2006

    • Author(s)
      Yoshio Tanaka, et. al.
    • Journal Title

      Proc. of SPIE (Optomechatronic Actuators Manipulation, and Systems Control) Vol.6374

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 光ピンセットレーザビームのパソコン制御による生体関連物質のマイクロ操作・加工2005

    • Author(s)
      田中芳夫, 他
    • Journal Title

      電子情報通信学会技術研究報告 Vol.105,No.222,MBE2005-54

      Pages: 61-64

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] ガラスキャピラリを用いた極微量溶液の描線法2005

    • Author(s)
      田中芳夫, 他
    • Journal Title

      計測自動制御学会論文集 Vol.41-11

      Pages: 942-944

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Micro manipulation and processing system for bio materials using PC controlled laser beams2005

    • Author(s)
      Yoshio Tanaka, et. al.
    • Journal Title

      IEICE Technical Report MBE2005-54

      Pages: 61-64

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] A drawing method of an ultra small amount of liquid onto a grass plate using glass capillary2005

    • Author(s)
      Yoshio Tanaka, et. al.
    • Journal Title

      Trans SICE Vol.41-11

      Pages: 942-944

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] レーザートラップによる円形加速度運動を用いたDNA1分子のサイジング2007

    • Author(s)
      平野 研, 他
    • Organizer
      第16回化学とマイクロナノシステム研究会
    • Place of Presentation
      つくば市
    • Year and Date
      2007-10-31
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Ken Hirano, et. al.
    • Organizer
      13th Microoptics Conference(MOC'07)
    • Place of Presentation
      Takamatsu,Japan
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Single molecule analysis of condensed DNA - Direct measurement of condensed speed and single molecule sizing by laser trapping -2007

    • Author(s)
      Ken Hirano, et. al.
    • Organizer
      13th Microoptics Conference(MOC'07)
    • Place of Presentation
      Takamatsu,Japan
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 光学顕微鏡下における非球状物の非接触3次元マニピュレーション2007

    • Author(s)
      田中芳夫, 他
    • Organizer
      第16回化学とマイクロナノシステム研究会
    • Place of Presentation
      つくば市
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 実時間画像処理による微粒子認識と光ピンセット捕捉2007

    • Author(s)
      川田博之, 他
    • Organizer
      第16回化学とマイクロナノシステム研究会
    • Place of Presentation
      つくば市
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 光圧力駆動マルチ細胞回収マイクロチップ2007

    • Author(s)
      長田英也, 他
    • Organizer
      第16回化学とマイクロナノシステム研究会
    • Place of Presentation
      つくば市
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Ken Hirano, et. al.
    • Organizer
      13th Microoptics Conference (MOC'07)
    • Place of Presentation
      Takamatsu Japan.
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Single molecule analysis of condensed DNA (Direct measurement of condensed speed and single molecule sizing by laser trapping)2007

    • Author(s)
      Ken Hirano, et. al.
    • Organizer
      13th Microoptics Conference(MOC'07)
    • Place of Presentation
      Takamatsu Japan.
    • Year and Date
      2007-10-30
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Optical multi-cell sorting on micro fluidic chips2007

    • Author(s)
      H.Nagata, et. al.
    • Organizer
      International Symposium on Microchemistry and Microsystems(ISMM2007)
    • Place of Presentation
      Tsukuba,Japan
    • Year and Date
      2007-10-29
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Optical multi-cell sorting on micro fluidic chips2007

    • Author(s)
      H. Nagata, et. al.
    • Organizer
      International Symposium on Microchemistry and Microsystems(lSMM2007)
    • Place of Presentation
      Tsukuba Japan.
    • Year and Date
      2007-10-29
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Single molecule analysis of condensed DNA - Measurement of condensation speed and single molecule size using laser trapping -2007

    • Author(s)
      Tomomi Ishido, et. al.
    • Organizer
      MicroTAS2007
    • Place of Presentation
      Paris,France
    • Year and Date
      2007-10-10
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Single molecule analysis of condensed DNA (Measurement of condensation speed and single molecule size using laser trapping)2007

    • Author(s)
      Tomomi Ishido, et. al.
    • Organizer
      MicroTAS2007
    • Place of Presentation
      Paris, France.
    • Year and Date
      2007-10-10
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Hideya Nagata, et. al.
    • Organizer
      MicroTAS2007
    • Place of Presentation
      Paris,France
    • Year and Date
      2007-10-09
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Multi-cell sorting on micro fluidic chip using optical gradient force2007

    • Author(s)
      Hideya Nagata, et. al.
    • Organizer
      MicroTAS2007
    • Place of Presentation
      Paris, France.
    • Year and Date
      2007-10-09
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] レーザマニピュレーションによる非球状物の3次元操作2007

    • Author(s)
      田中芳夫, 他
    • Organizer
      平成19年度電気関係学会四国支部連合大会
    • Place of Presentation
      徳島市
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 画像処理と光ピンセットの融合による微粒子自動操作2007

    • Author(s)
      川田博之, 他
    • Organizer
      平成19年度電気関係学会四国支部連合大会
    • Place of Presentation
      徳島市
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] レーザマニピュレーション技術と高度自動化技術の融合化によるマイクロ操作の高度化2007

    • Author(s)
      田中芳夫
    • Organizer
      四国テクノサイエンス研究会第94回研究会
    • Place of Presentation
      高松市
    • Year and Date
      2007-06-06
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 光学顕微鏡下における非球状物の非接触3次元操作2007

    • Author(s)
      田中芳夫, 他
    • Organizer
      ロボティクス・メカトロニクス講演会2007(ROBOMEC2007)
    • Place of Presentation
      秋田市
    • Year and Date
      2007-05-11
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Development of PC Controlled Laser Manipulation System with Image Processing Functions2006

    • Author(s)
      Yoshio Tanaka, et. al.
    • Organizer
      OpticsEast2006
    • Place of Presentation
      Boston,USA
    • Year and Date
      2006-10-03
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Development of PC Controlled Laser Manipulation System with Image Processing Functions2006

    • Author(s)
      Yoshio Tanaka, et. al.
    • Organizer
      OpticsEast2006
    • Place of Presentation
      Boston, USA.
    • Year and Date
      2006-10-03
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] レーザ光を用いた生体関連マイクロ物質の位置・姿勢の制御2006

    • Author(s)
      田中芳夫, 他
    • Organizer
      第45回日本生体医工学会大会(生体医工学)
    • Place of Presentation
      福岡市
    • Year and Date
      2006-05-15
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] ガラスキャピラリを用いた溶液微細描線の物理モデル2005

    • Author(s)
      田中芳夫, 他
    • Organizer
      平成17年度電気関係学会四国支部連合大会
    • Place of Presentation
      高松市
    • Year and Date
      2005-09-28
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 光ピンセットレーザビームのパソコン制御による生体関連物質のマイクロ操作・加工2005

    • Author(s)
      田中芳夫, 他
    • Organizer
      MEとバイオサイバネティックス研究会
    • Place of Presentation
      徳島市
    • Year and Date
      2005-07-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Patent(Industrial Property Rights)] 微粒子アレイの作成方法および装置2008

    • Inventor(s)
      田中芳夫, 川田博之, 平野研, 石川満, 北島博之
    • Industrial Property Rights Holder
      産業技術総合研究所
    • Industrial Property Number
      特許,特願2008-101060
    • Filing Date
      2008-04-09
    • Description
      「研究成果報告書概要(和文)」より
  • [Patent(Industrial Property Rights)] 極小線状柔軟物の切断方法及び切断装置2005

    • Inventor(s)
      田中芳夫, 平野研
    • Industrial Property Rights Holder
      産業技術総合研究所
    • Industrial Property Number
      特許,特願2005-330536
    • Filing Date
      2005-11-15
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2010-02-04  

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