2009 Fiscal Year Final Research Report
Investigation on the methods that will overcome crossing-fiber problem of diffusion tensor tractography.
| Project/Area Number |
19591429
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
YAMADA Kei Kyoto Prefectural University of Medicine, 医学研究科, 講師 (80315960)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMURA Tsunehiko 京都府立医科大学, 大学院・医学研究科, 教授 (70237733)
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| Co-Investigator(Renkei-kenkyūsha) |
SAKAI Koji 京都大学, 大学院・医学研究科, 助教 (20379027)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 交差線維 / 神経機能 / magnetic resonance imaging / 拡散強調画像 / 拡散異方性 / fiber tracking / tractography / fractional anisotropy |
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| Research Abstract |
The purpose of this investigation was to conduct a research on methods that will overcome the crossing-fiber problem on diffusion-tensor tractography. More specifically, we tested the feasibility of using high angular resolution diffusion imaging (HARDI)-based multi-tensor tractography to depict motor pathways. We tested this on patients with brain tumors. Ten patients were scanned using a 1.5T clinical MR unit. Data postprocessing was performed using both the conventional single- and multi-tensor methods. Motor fibers on both lesional and contralesional sides were successfully depicted by both the single-tensor and multi-tensor techniques. However, with the single-tensor model, the depiction of motor pathways was typically limited to the fibers of trunk areas. We also assessed the value of using high b-factor. This investigation indicated that the b factor between 1000 and 3000 will have less effect on the depiction of crossing fibers.
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[Journal Article] Multitensor tractography enables better depiction of motor pathways: Initial clinical experience using diffusion-weighted MR imaging with standard b-value.2007
Author(s)
Yamada K, Sakai K, Hoogenraad F.G. C, Holthuizen R, Akazawa K, Ito H, Oouchi H, Matsushima S, Kubota T, Sasajima H, Mineura K, Nishimura T
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Journal Title
AJNR Am J Neuroradiol 28
Pages: 1668-1673
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[Presentation] MR imaging of ventral thalamic nuclei.2010
Author(s)
Yamada K, Akazawa K, Yuen S, Goto M, Matsushima S, Takahata A, Nishimura T
Organizer
18th annual meeting of International Society of Magnetic Resonance in Medicine
Place of Presentation
Stockholm, USA
Year and Date
2010-05-05
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[Presentation] Multi-tensor tractography enables better depiction of motor pathways 15th annual meeting of International Society of Magnetic Resonance in Medicine2007
Author(s)
Yamada K, Sakai K, Hoogenraad FG, Holthuizen R, Akazawa K, Ito H, Oouchi H, Matsushima S, Kubota T, Nishimura T
Organizer
Proc. Intl. Soc. Magn Reson Med 15 p1546
Place of Presentation
Berlin, Germany
Year and Date
2007-05-22
