2009 Fiscal Year Final Research Report
Novel chaperonin-encapsulation system for aggregation-prone proteins.
| Project/Area Number |
19687010
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biophysics
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
HOSHINO Masaru Kyoto University, 薬学研究科, 准教授 (70304053)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Keywords | NMR / 分子シャペロン / GroE / 会合・凝集 / 構造生物学 |
|---|
| Research Abstract |
The protein has a central role in "vital activities", including digestion of foods, conversion of nutrients nto energy, and sensing external stimulations such as light or smell. These function of proteins depend n their specific tertiary structure, which could be visualized by nuclear magnetic resonance pectroscopy. A novel method which will allow the investigation of aggregation-prone proteins by NMR as developed.
|
