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2009 Fiscal Year Final Research Report

Abdominal obesity measured by multiple sliced CT, plasma adiponectin and colorectal adenoma

Research Project

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Project/Area Number 19689014
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionNational Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

Principal Investigator

SASAZUKI Shizuka  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん予防・検診研究センター 予防研究部, 室長 (50392337)

Project Period (FY) 2007 – 2009
Keywords内臓脂肪 / 大腸腺腫 / アデイポネクチン
Research Abstract

Among 1,205 eligible subjects who underwent PET-CT for cancer screening in Tokyo, visceral fat volume was associated with the prevalence of colorectal adenoma independently of body mass index in both sexes. Plasma level of C-peptide and IGFBP-1 were associated with colorectal adenoma among men but not women. An inverse and positive association of adiponectin and leptin was observed with colorectal adenoma, respectively.

  • Research Products

    (6 results)

All 2009 2008 Other

All Journal Article (4 results) Presentation (1 results) Remarks (1 results)

  • [Journal Article] Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Sakamoto H, Yoshida T, Tsugane S.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev. 18

      Pages: 267-274

  • [Journal Article] Visceral fat volume and the prevalence of colorectal adenoma.2009

    • Author(s)
      Yamaji T, Iwasaki M, Sasazuki S, Kurahashi N, Mutoh M, Yamamoto S, Suzuki M, Moriyama N, Wakabayashi K, Tsugane S.
    • Journal Title

      Am J Epidemiol. 170

      Pages: 1502-1511

  • [Journal Article] Dietary isoflavone and the risk of colorectal adenoma: a case-control study in Japan.2009

    • Author(s)
      Akhter M, Iwasaki M, Yamaji T, Sasazuki S, Tsugane S.
    • Journal Title

      Br J Cancer 100

      Pages: 1812-1816

  • [Journal Article] Development of an automated 3D segmentation program for volume quantification of body fat distribution using CT.2008

    • Author(s)
      Ohshima S, Yamamoto S, Yamaji T, Suzuki M, Mutoh M, Iwasaki M, Sasazuki S, Kotera K, Tsugane S, Muramatsu Y, Moriyama N.
    • Journal Title

      Nippon Hoshasen Gijutsu Gakkai Zasshi. 64

      Pages: 1177-1181

  • [Presentation] Methionine synthase A2756G多型と大腸腺腫との関連2009

    • Author(s)
      山地大樹、岩崎基、笹月静、坂本裕美、吉田輝彦、津金昌一郎
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      20091001-20091003
  • [Remarks]

    • URL

      http://epi.ncc.go.jp/mstudy/

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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