2009 Fiscal Year Final Research Report
Role of astrocyte in synaptic maturation during postnatal developing nucleus tractus solitarius
| Project/Area Number |
19700323
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Mie University (2008-2009)
Jikei University School of Medicine (2007) |
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Principal Investigator |
TASHIRO Yasura Mie University, 大学院・医学系研究科, 講師 (10398787)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 神経回路形成 / ニューロン・グリア相互作用 / アストロサイト / シナプス |
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| Research Abstract |
In developing nervous system, unnecessary synapses are eliminated. In the present study, the timing for glial coverage of small cell soma appears to be consistent with the decrease of axosomatic synapses on the small cells. Axosomatic synapses remained in adult stages under pharmacological inhibition of astrocytic processes extension during neonatal stages. These observations indicats that astrocytes could participate actively in regulating the decrease of axosomatic synapses on small cells in the caudal nucleus tractus solitarius during postnatal development.
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