2010 Fiscal Year Final Research Report
Molecular mechanism of urothelium regulating bladder function
| Project/Area Number |
20390425
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kyoto University |
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Principal Investigator |
NISHIYAMA Hiroyuki Kyoto University, 大学院・医学研究科, 准教授 (20324642)
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| Co-Investigator(Kenkyū-buntansha) |
OGAWA Osamu 京都大学, 大学院・医学研究科, 教授 (90260611)
NAKAMURA Eijiro 京都大学, 大学院・医学研究科, 講師 (90293878)
KANEMATSU Akihiro 京都大学, 大学院・医学研究科, 講師 (90437202)
YOSHIMURA Kouji 京都大学, 大学院・医学研究科, 講師 (40397542)
SODA Takeshi 京都大学, 大学院・医学研究科, 助教 (50422928)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 排尿障害 / 膀胱機能 / 尿路上皮 / 分子生物学 |
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| Research Abstract |
In this project, we engaged in clarification of the mechanism underlying change in bladder function with the molecules secreted from urothelium under stimuli. We demonstrated the physiological role of urothelium and the clinical condition of the bladder disease related with dysfunctional urothelium with combination of conventional pharmacological analysis, molecular biological analysis and new voiding behavior analysis.
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