2010 Fiscal Year Final Research Report
Change in blood pressure in hyperacute stroke patients evaluated using ambulatory blood pressure monitoring
| Project/Area Number |
20591039
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurology
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
TOYODA Kazunori National Cardiovascular Center Research Institute, 脳血管内科, 部長 (50275450)
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| Co-Investigator(Renkei-kenkyūsha) |
KOGA Masatoshi 独立行政法人国立循環器病研究センター, 脳血管内科, 医長 (30512230)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 脳梗塞 / 急性期 / 血栓溶解療法 / 血圧 / 降圧 |
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| Research Abstract |
Low levels of systolic blood presssure (BP), diastolic BP, and heart rate (HR) on day 2, as well as low HR level on day 8, assessed using ambulatory BP monitoring were associated with 3-month favorable outcomes in acute stroke patients. Low levels of systolic BP, pulse pressure, and HR during the initial 24 hours after rt-PA therapy, especially at 8 hours thereafter, were associated with 3-month favorable outcomes in the patients treated with rt-PA.
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