Evaluation of Magnetic Stimulation on Oral Tissue by Genomic Response

2010 Fiscal Year Final Research Report

• Project/Area Number: 20592293
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Aichi Gakuin University
• Principal Investigator: TANAKA Yoshinobu Aichi Gakuin University, 歯学部, 教授 (60014271)
• Co-Investigator(Kenkyū-buntansha): OZAWA Shogo 愛知学院大学, 歯学部, 准教授 (50323720) ; NAKAMURA Yoshinori 愛知学院大学, 歯学部, 准教授 (70308782)
• Project Period (FY): 2008 – 2010
• Keywords: 変動磁揚 / 骨芽細胞 / 遺伝子発現 / マイクロアレイ

Research Abstract

This experimental study describes extremely low magnetic fields (ELMF) of 0.4T and 0.17Hz stimulated mouse osteoblast-like cell proliferation at early stage, and differentiation to mature osteoblasts, whereas fibroblasts did not show significant differences in proliferation by the exposure. These results suggested that osteoblasts have specific response on the magnetic fields, and then bone formation could be accelerated through stimulated osteoblasts by ELMF. Microarray gene analysis revealed that ELMF stimulated genes expressions were extracted.

Research Products

• [Journal Article] 歯冠外アタッチメントとしての有髄歯への適応 (2010)
  • Author(s): 岡田通夫, 中村好徳, 田中貴信
  • Journal Title: 日本磁気歯科学会雑誌 19(1) Pages: 29-38
  • Peer Reviewed
• [Journal Article] 鋳造用磁性合金で作製されたキーパーの厚径に対する吸引力の影響 (2010)
  • Author(s): 岩井孝充, 宮田利清, 中村好徳, 吉原健太郎, 熊野弘一, 大野芳弘, 大野友三, 今井勢喜, 高田雄京, 田中貴信
  • Journal Title: 日本磁気歯科学会雑誌 19(1) Pages: 47-53
  • Peer Reviewed
• [Journal Article] 三次元有限要素法を用いた磁性アタッチメントの吸引力特性について-キーパーサイズの変化が吸引力に及ぼす影響- (2010)
  • Author(s): 熊野弘一, 増田達彦, 中村好徳, 神原亮, 岩井孝充, 秦正樹, 松川良平, 大野友三, 今井勢喜, 高田雄京, 田中貴信
  • Journal Title: 日本磁気歯科学会雑誌 19(1) Pages: 54-60
  • Peer Reviewed
• [Journal Article] Influence of the measuring methods on the attractive force of magnetic attachments. (2010)
  • Author(s): 中村好徳, Shoji K, Kanbara R, Kumano H, Ando A, Iwai T, Kogiso T, Ohno Y, 田中貴信, Tanaka Y
  • Journal Title: J J Mag Dent 19(2) Pages: 10-15
• [Journal Article] Influence of cast magnetic alloy keeper thickness on the attractive force of a magnetic attachment. (2010)
  • Author(s): Iwai T, Nakamura Y, Shoji K, Masuda T, Kanbara R, Yoshihara K, Hata M, Ohno Y, Takada Y, Tanaka Y
  • Journal Title: J J Mag Dent 19(2) Pages: 16-18
• [Journal Article] Stress analysis of an abutment tooth with extracoronal magnetic attachment -Introduction of nonlinear property into three-. (2010)
  • Author(s): Kanbara R, Nakamura Y, Ando A, Kumano H, Masuda T, Sakane M, Ohno Y, Matsukawa R, Takada Y, Tanaka Y
  • Journal Title: J J Mag Dent 19(2) Pages: 44-51
• [Journal Article] Attractive force analysis of magnetic attachment using three dimensional finite element method-Influence of the keeper thickness on attractive force-. (2010)
  • Author(s): Kumano H, Masuda T, Nakamura Y, Miyata T, Iwai T, Kogiso T, Ohno Y, Matsukawa R, Takada Y, Tanaka Y
  • Journal Title: J J Mag Dent 19(2) Pages: 52-55
• [Presentation] Effect of Magnetic Fields on Osteoblasts and Fibroblasts in vitro. (2011)
  • Author(s): Fukuzawa R, Ozawa S, Kubo K, Sugita Y, Yoshida W, Maeda H, Tanaka Y.
  • Organizer: The 3rd Academy of Advanced Applied Science in Oral Medicine.
  • Place of Presentation: Tokyo
  • Year and Date: 2011-01-22
• [Presentation] 骨芽細胞と線維芽細胞における磁場刺激に対する反応について (2010)
  • Author(s): 福澤蘭, 尾澤昌悟, 前田初彦, 久保勝俊, 杉田好彦, 吉田和加, 田中貴信
  • Organizer: 第20回日本磁気歯科学会
  • Place of Presentation: 名古屋
  • Year and Date: 20101030-20101031
• [Book] スタンダード部分床義歯補綴学 第2版(藍稔 五十嵐順正編)(第23章その他の義歯) (2010)
  • Author(s): 尾澤昌悟,田中貴信
  • Total Pages: 239-245
  • Publisher: 学建書院
• [Book] 無歯顎補綴治療学第2版(細井紀雄, 平井敏博, 大川周治, 市川哲雄編)(顎義歯による治療) (2009)
  • Author(s): 尾澤昌悟,田中貴信
  • Total Pages: 294-301
  • Publisher: 医歯薬出版