Atmospheric behavior and health effect of polycyclic aromatic compounds formed via reactions on Asian dust surface

2011 Fiscal Year Final Research Report

• Project/Area Number: 21200031
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
• Allocation Type: Single-year Grants
• Research Field: Risk sciences of radiation/Chemicals; Environmental pharmacy
• Research Institution: Kanazawa University
• Principal Investigator: KAMEDA Takayuki 金沢大学, 薬学系, 助教 (50398426)
• Co-Investigator(Renkei-kenkyūsha): HAYAKAWA Kazuichi 金沢大学, 薬学系, 教授 (40115267) ; TORIBA Akira 金沢大学, 薬学系, 准教授 (50313680) ; TANG Ning 兵庫医科大学, 医学部, 助教 (90372490)
• Project Period (FY): 2009 – 2011
• Keywords: 黄砂 / PAH / 越境大気汚染 / 健康影響

Research Abstract

The aim of this study is to elucidate atmospheric formation of toxic polycyclic aromatic hydrocarbons (PAH) derivatives on the surface of Asian dust particles transported from the Asian Continent to Japan and to evaluate adverse health effects induced by the compounds. We performed chemical reaction experiments of PAHs on the Asian dust particle surface using a reaction-chamber, and investigated the formation of substituted PAHs on the particles.

Research Products

• [Journal Article] Atmospheric formation of hydroxynitrofluoranthene from photo chemical reactions of 2-nitrofluoranthene (2012)
  • Author(s): T. Kameda, A. Akiyama, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: Polycyclic Aromat. Compd. Volume: (in press)
  • DOI: DOI:10.1080/10406638.2011.654307
  • Peer Reviewed
• [Journal Article] Determination of Benzo[a]pyrene-7, 10-quinone in Airborne Particulates by Using a Chemiluminescence Reaction of Hydrogen Peroxide and Hydrosulfite (2012)
  • Author(s): R. Li, T. Kameda, Y. Li, A. Toriba, N. Tang, K. Hayakawa, J.-M. Lin
  • Journal Title: Anal. Chem. Volume: 84 Pages: 3215-3221
  • DOI: DOI:10.1021/ac2032063
  • Peer Reviewed
• [Journal Article] Hydrogen peroxide-sodium hydrosulfite chemiluminescence system combined with high-performance liquid chromatography for determination of 1-hydroxypyrene in airborne particulates (2011)
  • Author(s): R. Li, T. Kameda, Y. Li, A. Toriba, N. Tang, K. Hayakawa, J.-M. Lin
  • Journal Title: Talanta Volume: 85 Pages: 2711-2714
  • DOI: DOI:10.1016/j.talanta.2011.08.005
  • Peer Reviewed
• [Journal Article] Atmospheric formation of hydroxynitropyrenes from a photochemical reaction of particle-associated 1-nitropyrene (2011)
  • Author(s): T. Kameda, A. Akiyama, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: Environ. Sci. Technol. Volume: 45 Pages: 3325-3332
  • DOI: DOI:10.1021/es1042172
  • Peer Reviewed
• [Journal Article] Atmospheric chemistry of polycyclic aromatic hydrocarbons and related compounds (2011)
  • Author(s): T. Kameda
  • Journal Title: J. Health Sci. Volume: 57 Pages: 504-511
  • DOI: DOI:10.1248/jhs.57.504
  • Peer Reviewed
• [Journal Article] Mutagenicities and endocrine-disrupting activities of 1-hydroxy-2-nitropyrene and 1-hydroxy-5-nitropyrene (2011)
  • Author(s): T. Kameda, A. Akiyama, M. Yoshita, C. Tachikawa, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: J. Health Sci. Volume: 57 Pages: 372-377
  • DOI: DOI:10.1248/jhs.57.372
  • Peer Reviewed
• [Journal Article] Determination of particle-associated hydroxynitropyrenes with correction for chemical degradation on a quartz fiber filter during high volume air sampling (2010)
  • Author(s): T. Kameda, A. Akiyama, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: Intern. J. Environ. Anal. Chem. Volume: 90 Pages: 976-987
  • DOI: DOI:10.1080/03067310903359484
  • Peer Reviewed
• [Journal Article] Determination of airborne particle-associated benz[a]anthracene-7,12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection (2009)
  • Author(s): T. Kameda, T. Goto, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: J. Chromatogr. A Volume: 1216 Pages: 6758-6761
  • DOI: DOI:10.1016/j.chroma.2009.08.009
  • Peer Reviewed
• [Presentation] 越境輸送中の黄砂粒子表面におけるニトロ化多環芳香族炭化水素の二次生成 (2011)
  • Author(s): 亀田貴之, 安積愛理, 松木篤, 唐寧, 福島杏希, 鳥羽陽, 早川和一
  • Organizer: 第52回大気環境学会年会
  • Place of Presentation: 長崎大学(長崎県)
  • Year and Date: 2011-09-14
• [Presentation] 黄砂粒子表面における多環芳香族炭化水素のニトロ化と越境輸送 (2011)
  • Author(s): 亀田貴之, 安積愛理, 唐寧, 松木篤, 福島杏希, 鳥羽陽, 早川和一
  • Organizer: 第20回環境化学討論会
  • Place of Presentation: 熊本県立大学(熊本県)
  • Year and Date: 2011-07-14
• [Presentation] 越境輸送中の黄砂粒子表面におけるニトロ化多環芳香族炭化水素の二次生成 (2011)
  • Author(s): 亀田貴之, 安積愛理, 松木篤, 唐寧, 鳥羽陽, 早川和一
  • Organizer: 日本薬学会第131年会
  • Place of Presentation: 静岡県立大学, ほか(静岡県)
  • Year and Date: 2011-03-28
• [Presentation] 黄砂粒子表面における多環芳香族炭化水素のニトロ化と越境大気汚染の可能性 (2010)
  • Author(s): 安積愛理, 亀田貴之, 松木篤, 唐寧, 鳥羽陽, 早川和一
  • Organizer: 第51回大気環境学会年会
  • Place of Presentation: 大阪大学(大阪府)
  • Year and Date: 2010-09-08
• [Presentation] 日本および中国における大気粒子中多環芳香族炭化水素キノンの観測:濃度レベルの把握と発生要因の検討 (2010)
  • Author(s): 亀田貴之, 後藤知子, 鳥羽陽, 唐寧, 早川和一
  • Organizer: 第19回環境化学討論会
  • Place of Presentation: 中部大学(愛知県)
  • Year and Date: 2010-06-21
• [Presentation] 光反応により生成する大気粒子中新奇ニトロピレン水酸化体の同定および定量 (2009)
  • Author(s): 亀田貴之, 秋山鮎子, 鳥羽陽, 唐寧, 早川和一
  • Organizer: 第50回大気環境学会年会
  • Place of Presentation: 慶應義塾大学(神奈川県)
  • Year and Date: 2009-09-16
• [Book] Photochemical degradation of selected nitro-and oxy-polycyclic aromatic hydrocarbons on airborne particles under simulated solar UV-irradiation, Airborne Particulates, (Ming Cheng and Wen Liu, eds.) (2009)
  • Author(s): T. Kameda, Y. Nakayama, T. Goto, T. Koyanagi, H. Bandow, K. Fujimori, A. Toriba, N. Tang, K. Hayakawa
  • Total Pages: 291-307
  • Publisher: Nova Science Publishers
• [Patent(Industrial Property Rights)] 砂塵飛来有害物質及び微生物除去剤,砂塵飛来有害物質及び微生物除去セルロース繊維及び繊維構造物 (2011)
  • Inventor(s): 山田丸, 亀田貴之, ほか 6名
  • Industrial Property Rights Holder: 金沢大学, ダイワボウホールディングス(株), ダイワボウノイ(株)
  • Industrial Property Number: 特許, 特願2011-155806
  • Filing Date: 2011-07-14
• [Patent(Industrial Property Rights)] 芳香族ニトロ化合物の製造方法 (2009)
  • Inventor(s): 亀田貴之, 松木篤
  • Industrial Property Rights Holder: 金沢大学
  • Industrial Property Number: 特許, 特願2009-246879
  • Filing Date: 2009-10-27